Basic Information

Insect: Glossina fuscipes
Gene Symbol: zfh1
Assembly: None
Location: Scaffold383:318888-323607[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00052 0.041 14.5 1.6 1 23 342 365 342 365 0.97

2 11 0.0099 0.8 10.4 0.4 1 21 433 453 433 454 0.95

3 11 0.00016 0.013 16.1 0.1 1 23 462 484 462 484 0.98

4 11 0.0067 0.54 11.0 0.6 2 23 489 511 488 511 0.95

5 11 2.6e-06 0.00021 21.7 1.5 2 23 518 539 517 539 0.98

6 11 2.8e-08 2.2e-06 27.9 1.7 1 23 545 567 545 567 0.95

7 11 0.0018 0.14 12.8 0.6 1 23 573 595 573 595 0.99

8 11 3.8e-07 3.1e-05 24.3 1.9 1 23 601 623 601 623 0.98

9 11 0.015 1.2 9.8 0.6 1 23 629 651 629 651 0.98

10 11 8.3e-05 0.0067 17.0 7.3 1 23 657 679 657 679 0.99

11 11 0.00091 0.073 13.7 1.7 5 23 687 706 685 706 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00052	0.041	14.5	1.6	1	23	342	365	342	365	0.97
2	11	0.0099	0.8	10.4	0.4	1	21	433	453	433	454	0.95
3	11	0.00016	0.013	16.1	0.1	1	23	462	484	462	484	0.98
4	11	0.0067	0.54	11.0	0.6	2	23	489	511	488	511	0.95
5	11	2.6e-06	0.00021	21.7	1.5	2	23	518	539	517	539	0.98
6	11	2.8e-08	2.2e-06	27.9	1.7	1	23	545	567	545	567	0.95
7	11	0.0018	0.14	12.8	0.6	1	23	573	595	573	595	0.99
8	11	3.8e-07	3.1e-05	24.3	1.9	1	23	601	623	601	623	0.98
9	11	0.015	1.2	9.8	0.6	1	23	629	651	629	651	0.98
10	11	8.3e-05	0.0067	17.0	7.3	1	23	657	679	657	679	0.99
11	11	0.00091	0.073	13.7	1.7	5	23	687	706	685	706	0.95

Sequence Information

Coding Sequence: ATGGATGTTGAAAAGATCTGCAGAACGTGTTTAACATTAAGTGGTCCATTGCTTTCAATTTATGATGATGGTAAGGGTGGTTCTGGTTGTTTGGCTGATATGTTACGGGAATTCACTAAAACCAAGCCTCAGTGTAACGACAACCTACCGGAACGCGTATGCCTTTCATGCATAAGCGAAATTAACCGCTGTTATTCATTTAAATTGAAATGTGAAAATTCCAGCAAAACACTCCAACAATTAATACCGAATGCCAAAGGCTTGCCAGACGTTACCGAAAAGTCGGTATCTAACTGTGAAAAGGCAGTGCAGACAAACAAAAGAGCACTTATCTCTACATATGTTCAGACGTTTGCTTTGTTCAAGGACAAGGAAATACAAACTGAAGCACGAGATGCAATGCAAAATTTTAAATTTGAAAGATCTTCAGAGCTCTCAAACGCTCCACGCTCAAACAATCCCGTCCGTTGTTTTAAGCGTTCGACAGACTTAGAAGCAAACGTTCACACGTTGTCTCGTCaaaaaaaTCCTGATAAAGTTTGCAATAGACTGTGCTTTGACACTAATTTAAAAGATACTGCTCTGAAAGCAGCGGAAATGGCGCGGGAGGAAGCCTATATTCTATTAGATAACAGTTCAACAGAAAATGATAAGTTTTACATACGTAGTGAATCAGATAATATAGGAGCGCAGGATTCGATCAACGTTGTTTTATCGAATCATTTCGAATTTTACAATGACGAAGACGAACTCGATGAAGATAATCGAACGGAGGAACATGATTACTCTTGTGGAAATGTGGACATTCCTGACATCAATTGTGCAACAGATCAATCACTAGTCGCCAACGGTGTGTTGTGTAAAATTAATAGACACTTTGATTCCGCTTCTGATGAAGATGGCCACAGCTGGGATAAGGAGGAACACAGAGCAACAAACTCTGCCAGCTCGCAACTCACGGACAAGCAGTCTGGTCCTGTAGCAATCATTAGCTCAAGTCGTTTGGATTCAAATAGGGAAGAGTACCGATGCCCATACTGTATTATGACTTTCGTCAGCTTGAAAACTCTCAGGCGTCATTTATCCAAACGCCACAACCTAGAACTTGAACCATCCCAAATTATTATTGAGaaaaaagtaaaaaaGTCTGTTGAAACCATAGAGGAGAAGATTGATGAATCTGCAGGCAATGAGCAGAAAAACTTGACAAAGGGAAATGTACTAAAGCCTCACTTAATGCCGCGAGACCGTGTTTCAACTTCTAAATCGGACGAAGCCGCATTAACCACTTTTCAATACTTTTGCGATTATTGTAAAGCTGGCTTTGCATTGCGCAAAACTCTAACTTTGCATATGAATCAAAACTTGTGCACCTCCAATAATTTTAAGTGCGACGCATGTGGAAAAATTTTCTTAACCGAAAAGAATTTAGAAGCACATATCGCTACGCACACGAATGAACAAACTTGTTTGGAGTGCAAGAAAACATGTGGGAGCATAGAGGAACTTAGCGCACACATGATTAGTGAACATAATCGAAATCCCCGCAATCAGTGCAAAGTTTGCAAAAAAGTATTCACTATGAAGACATCACTTATGGATCACATGCGCATACATTCCGGTGAAAAGCCATTTCTCTGTACAATATGTGGGAAAAGCTTTCGTCAAAACTCAAACTTACGACAACACTTAATGCGACATACGAATGAGAAAAATTTTAAGTGTGATGTATGTTTAAACGCTTATGTAACCAAAGCTGAATTGTTTTCTCATAAACGTTCACACACTGGTGATCATCCGTTTAACTGTGAAATATGTGGATCGAGTTTCACATCTTCAAGCTCTTTGCAGAAACATCGTCGCAAACACACTGGAGAGCGGCCGTATGCCTGCGAGTTTTGTCCCATGCGTTTTACTGCTTTAAATATATTGAAAAATCATCGTCGTACTCACACCGGCGAAAAGCCCTTCAAATGTGAACATTGTAATAAAAGTTTTTCACAAAAGGGCGATTGTCAGATGCATCAAAGGACTCATGGTGAAAAGGATTTCAGCTGCGTGTGCGGCGCTAAATTTTCGAAGTCCTCTAATTTACGTTATCATAGGCGAAGACAACATTGCCGATTTTCAGATGGAGATGCCGCAAGTGAACAAGATGCTATGGATAATGCAGAAATGCATATAACTTTAGTAAAAGATGAAGATGGCGACGAACTTATTACTATCTCTACAAAGGGAGAACGAGAGAACGCAAATAAACATAAGCTCGGACTTGGTATACAAAACGAAGAGGAATTGTTGGACATTGCCATGGAAGATATATGTTAA
Protein Sequence: MDVEKICRTCLTLSGPLLSIYDDGKGGSGCLADMLREFTKTKPQCNDNLPERVCLSCISEINRCYSFKLKCENSSKTLQQLIPNAKGLPDVTEKSVSNCEKAVQTNKRALISTYVQTFALFKDKEIQTEARDAMQNFKFERSSELSNAPRSNNPVRCFKRSTDLEANVHTLSRQKNPDKVCNRLCFDTNLKDTALKAAEMAREEAYILLDNSSTENDKFYIRSESDNIGAQDSINVVLSNHFEFYNDEDELDEDNRTEEHDYSCGNVDIPDINCATDQSLVANGVLCKINRHFDSASDEDGHSWDKEEHRATNSASSQLTDKQSGPVAIISSSRLDSNREEYRCPYCIMTFVSLKTLRRHLSKRHNLELEPSQIIIEKKVKKSVETIEEKIDESAGNEQKNLTKGNVLKPHLMPRDRVSTSKSDEAALTTFQYFCDYCKAGFALRKTLTLHMNQNLCTSNNFKCDACGKIFLTEKNLEAHIATHTNEQTCLECKKTCGSIEELSAHMISEHNRNPRNQCKVCKKVFTMKTSLMDHMRIHSGEKPFLCTICGKSFRQNSNLRQHLMRHTNEKNFKCDVCLNAYVTKAELFSHKRSHTGDHPFNCEICGSSFTSSSSLQKHRRKHTGERPYACEFCPMRFTALNILKNHRRTHTGEKPFKCEHCNKSFSQKGDCQMHQRTHGEKDFSCVCGAKFSKSSNLRYHRRRQHCRFSDGDAASEQDAMDNAEMHITLVKDEDGDELITISTKGERENANKHKLGLGIQNEEELLDIAMEDIC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00749874;
90% Identity: iTF_00749874; iTF_00750645;
80% Identity: -