Basic Information

Insect: Glossina morsitans
Gene Symbol: TRERF1
Assembly: None
Location: scf7180000640591:10774-52521[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 4.3e-05 0.0023 17.8 0.3 2 23 392 413 391 413 0.97

2 6 1.9e-06 0.0001 22.0 1.5 1 23 419 441 419 441 0.99

3 6 0.00011 0.0059 16.5 2.6 1 23 447 471 447 472 0.95

4 6 0.00037 0.02 14.8 1.3 2 23 706 727 705 727 0.97

5 6 0.0015 0.083 12.9 0.2 1 23 1839 1863 1839 1863 0.97

6 6 8.6e-05 0.0047 16.8 0.8 1 23 1926 1948 1926 1948 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	4.3e-05	0.0023	17.8	0.3	2	23	392	413	391	413	0.97
2	6	1.9e-06	0.0001	22.0	1.5	1	23	419	441	419	441	0.99
3	6	0.00011	0.0059	16.5	2.6	1	23	447	471	447	472	0.95
4	6	0.00037	0.02	14.8	1.3	2	23	706	727	705	727	0.97
5	6	0.0015	0.083	12.9	0.2	1	23	1839	1863	1839	1863	0.97
6	6	8.6e-05	0.0047	16.8	0.8	1	23	1926	1948	1926	1948	0.98

Sequence Information

Coding Sequence: ATGGCAACCATAAACTCGGTACCGAAAAGTATACACCTGCCGTTAGCTGGTCTCCCTGCGACGCCGCGTGTGCTCATGTGCAGTGCTTCAGTGGGCACGGAAGGTTCGGTTACTTTAAAATTACGCGATGCCAATTCATCGTCCTCGCCTTCGTCCGATTCCAATCAATCAGTGTCGACAGTCGCATCAAACGCTTCAAATGCAGTCAGCAGTTTGGATAATGCGTTAACCATTGGCTATCCGGATCCGGAAATGTTGGCTGATGTATTGGGCACTTTGCAAACGGCTTCCCTAAATAATAATAATCATTATCGTAGTAATGGTAATGAATGCAATAGCAAAGTGCAAATAAATAAATTAaacacaatcgtaacaacaggagcggcaacaccaacaacaacagcagcaacagcaacagcaacgacaattaacagtgataacaatcccaataatatcaataccaatcatggtaataatcaaaataacaatgttgcgaatactaataattgcattaacaacattaaaaacTGTGCGAATAATTTAAAAAGTCGTGTAACCATTAGTCGTCGTACCTCAAACGTAGCGCACAGTTCACAAACCCAAAAAGATTCCCCTAAATGTACGATAGCGGCCGCTGTTCAAACTGTATCcatctcaacaaataccaccaacaagactaacagttatattaaaaattgcttgatacgcagtagcagttgcaataataccaccaatattacatcattggctcaaataatgagcaatagcagttcgagtaacagcaacagcaacagcaacatcaacagcaacagcaacagtaacagcaacaacaataacaataacaacaacaataacaacaacaacagcaacagcagcagcaacaacaataataacgctagcagtacctttcaacaatttcaaagcagtagcaacagtaatttgtcatgcagcaatagcaacagcaattgcagcagtaacagtaactacagttcaaacagtaacgatagttgttttagtataactagtagcagcaatagcagcagtggcaacaTAAGTGTACGTTGTGCCCCCATTCCCTGTAATCGCAAAGTTCCTGTTTCATTAACAAATCCACCGAAAATACTGaaaaaaaaCCGTTCAAAACTATCTTCGCCTAGCCGTCACGGTCCACAACAGTGTCAGatttGCAATAAAATATTTGGAAATGCATCAGCACTGGCTAAACATAAATTGACGCACAGTGACGAACGGAAATACGTGTGTGTTATGTGCTCAAAAGCATTTAAACGGCAGGATCATTTAAACGGTCACATGATGACGCATAGAAATAAAAAACCATACGAATGTAAAGCTGAGGGCTGCGGTAAATCTTATTGTGATGCACGTTCCCTTCGTAGACATACCGAAAATCATCATGCTGGCGTTATAACCCCGCAAAATCAAAACTTATCATCTATTAACGTCAATTGTTCATCAGCAAATCTAAGTTTATCACCAGCTACCGCAAACGGGGATGCAAGCTCACCAGATGGTGCAACATGTTTGGGTACGTATCTTTCGAATGGCGGTACAGTGGTTGACGCTTCAACTGGTTTAGCTTTAACTGAAGACGAGGTGAAGGCTTTAAAGACCAATGTTACATTGCTATCACCCACCTCTACTCTTTCTTCTTCTTCGTCGTCGGCTAGTAGTATCGCCTCGACATCGACTGCAGCCACTATAACTTTAACAGATAGCGGTGGCAATATGGAGGGCGAAGGTCTAACCCCCGAACAGTTAGACTTGATTAGTAAAATTATGCGTCAGACTAAGCAAACAACAGCACAGGTAACCGTGTCCTCACACTCCAGTTCACAATCCTATAAAATCGACACATCACCGGCCCAGACGCAAACTCAGAATCCAAGACCACGAACCTGGAATATGCAATTGCTAAACACCACTCAGAACTTGGCCATTACCGTGGATGAGGTGTCCAATGATGCTATACCTCGCAATATAGATTCACCACTATTGGCCATGGACGCTAAAGAAGAGGAAGTCAAGATAGATTTGACTTCCGGCCTGAACTCCTCTTCGTTATTAAATGTAGTTAAAATTGATCAAAAGCCAGTGGAATGTAATTTATGCCATCGCAAATTTAAGAACACGCCGGCCTTAAACGGTCACATGCGTTTGCATGGCGGTTATTTTAAAAAAGATCCCGAGACTaaaaaaaGCGAGAAAAAGGAGAATAATGGTCCGCCCTTGCAAACAGCTAGCATTGGTGTTCGAGCCCTAATCGAAGAGAAAATTATTAACAAGCGAAGTAGAGATATAAATAAGGGTTCTTTTGCCGTACCTGCTCCGCCTACCAATAATTTAGCCAATAATCCGATCTTGCGGAGATCAATTAGCGATTTGGAAAATTTCCTAAGTTCTAAAAATCAGACAAGTTCTGGTAGTTGCATATCATCGAATCTGAACACGATGTCTACCCCTTCAGTCGCTTTTAAAAATAATAATAGAACTATGCTTAATGCCCAGGATATGGGTTTACCTCAGAGTATTGAAATCTTCAGTACCAAACAACAAAAACCAATGAATAATGTGAGCGTGGGAGTGGGCACGAATCTCACTCAGCTGAATAGCGGTGAATGCAGTTCAGTGACAACGACAGAAAAACCAGTAACAACGACGTTGAACACAACGACTTCTACAGGAACAACAACCCGCAGCACATCAACTGATCCAAAAGATTCCACTTTAATAGAATTACTAAAGAGAGGAACACGTATCGCTGTCACGTCCAAGCAAGCATCAAACGCGCCATTGGGTGGCGTGACGCGCCAAATCGTTAATACCACCACCACAACAAATTCTCCTTCAAGGGCAGTACTTATACCCTCCGATGTACAAGTTATTAATAACAAGGTAAAGCTGGCAACCACAACCCAAGAAATCGAGAATTCATTAAACAATTGCCCAGAATCCACTGGTATATCGCTAGCGCAAAGTTCCCCGTTGTCCTTGACATTATCGCAGAATGGAGATGTCAACGCAGAAGTGTACACTGTCACTTATGCCAGTGACAATTCTAATTTGTTTGAAGAAACTGAGGTTTACAATGTCAGTGAGGCCGAAATGCTATTGCAAACAGTAGACACAATGCAATTGTTGAATGATTCCAATCATGAAAACCTGCTCAAATCTTCTGAACATTCCGAACAATATGAAATTATAGATAATAATGGTCAAGTATTGCAGCCCTCTTGTCCAACGGATATTAATAATGGCTCAGAATGTAAGCAACAACAAATTTTGCCGAATTTTCAACATTTCCATTCCAAAGAACTACTAATGAATCCTTTAACTCAATCCAATGGAAGTTTAAACTCCTTGTCCATGCCATTAGTTGAAAGGAAACAACTTTATGGGAGGCTGAATTCTCCTTTGCATTCTCCATTAGCCTATCCGACTCCTCCCTCCAGCCACGAAAATGTTACTCAAACTTCTCCTTACGTAGACGATAATCAACAGTATGGCGAAACATCGAATGTCTTTTTTAGCGAATCGTTAATAAGTAACGCTTCAACAAGTGCAACTGGAGAAATGGAGAATGAAAAACTAACAAAGCTAGGAAATATTATGGGAGATAACAATTTCGATAATAATAATATTAAGATGGAGGATTTACTTAGTGATACCAATACGGATGCGGAACGTGATTTAAGGGAATTCGCCGAAGCCAATCTTTCATTTCTAGATGAGGAACAGGAGTTTCTAAATGATTCGGGCAACGCTGCGTCTCCGTTATCGGAGTCTTTCTTTAGCGGGGGCATAGGTTCAGTAGAAGAGGTGAAAGAAGTATTACGTGAGGTCTTAACCGAAGATCAAATACAAATCAATTGCGAAAGTCAATCAGAGAACATAATCGATTTGTATTACTTGCCTTGCTTAAGTTTGCAGTCACAAATGATGCCAAATTCGGAAGATCCGTTGCTGTCATCTTCACCTCGTGATTTTGGTCAGCAGAAATTGACTCAAACAGCAAATAATACAAGCCAACACATTCCTCACCAACAACAACCAAACCTAAATCCAAATGCCTCGACCAATACAAGCCAGAATCCATACCTGCAGAGTAATAAtgctgcgatttcagtacaactacaacaacagcagcagcagcatcagcatcagcagcagcagcaaccaccacaacagcagcaAGGCGTATTAAAGATGCAGCCACTGCAAACGCAACAAATGCCTTCAGAGATTAATCAGGTTATTGTAACAGTACCGGCCAATGGTTGTGGCAATACGGCCTCTATCATGCAGTACAATTTTCAAAACACACCGCAAGTACAAATTCCAACAAATACCCAGCAATATATTGACTCCGCCAATCAATCACATACACAAGCTAGCAATAGCACCAGTAGCAATAGAACAATAACAGCGCAGTTAAATGAGGCCTTAACGCAGCCCCTTGTTTACACAGGAACCACCGAAAGATCAGAAATGAAATTAATGCCAACACAAAATCACAACCGCCTTAATTTAAATATTGAGCAAAGGCAACAAGAGACCCAACAACGGTTGCAAATTACTGATGTCTTAAATAATTCTAATATTTATTATGGACAAATCGCGTCCAATGAGCAACAGCAAACGCCTCAGTATTGTCAGACGTCAAATGCGATGAATAGCACATCAGTGTTGACTACCATTCTACAGCCATTATCCAATCAAACTAATTCCATATTAAAAAGACGTCTAAGAGGGTATAATTCCTCGGATTCGGGCTCTTCTGGTTATCAGTTAAAGTTCCAAACTTTATCTCCGTACCGTTCTAAATTAAGGAAACCCTCAAGGACTCATTACACACCTGCTCCAATTTTAAACCCCGCCCGCAAAGGCCACGGTTTGTATTGCAACATTCTTAAGGAATCGAATGGTAATCTTTCAGCATTTGATGCCTTCGACGATGATTTCGAGGACTCAGTGGGCTTAGTGGATTTCTCAGATGTGTCTAAAGTTAATTTAGGATCAGCATATCAAGCTGCCATACCAATTTTTAAAGAGCGATCCGCATTAACAGCAATTGACGAGCCCGTAAAAGCGGAACTCATGTGGAATCCGGACATTCAAAGGGATGAAAATATATTGATGCGTTTTATAGATCTTAGCAAATCATCGGCGACGCCTTCGGGAAGTCATACAGAAGAAATAGCATTAAAGACACTGCTTAAATCCCATGGTAACACCGCTTCAGCAGTTTTAACTCTACTACAAACCCAGTCAAATCCATTCCAAATGAAATGGTCCGCTCAAGAATTGGAAACTTTCCTGAAGGGATTGGAGAAATATGGCAAGGAATTTAGCAAAATTTCCAAAGAGCTTGGTTCTAAAACAACTGGAGAATGTATACAAATCTATTACTTTTGGAAGAAGCTGTGTGTAGATTACAAGGTCACCCACCTAAAAACTGAAACACCGCCGGTCAACCACAGCAATGAAGTGAAACCATACGTATGTGAACAACCTGATTGCTCAGCGAGCTTCTCTTCAAAAGCTGCTCTGCATGGCCATACTCGCATACATACCTATGGTCGCAATAGCCACAATAATAATCACAGTGCCACTAATCCAAACGCTAACAACTCCTTACCCGGCTCGATCAGTTCAACTAGTGCATGTACCGCCTCATCTCAGGCACTTAGTCACTCAGTAAATTTAGTAAATAAAGATAACACCACTGCAACCAATACCAAAGATATCAACAACGATTTCCCCTGCAAGGTGTGCGGCAAAGTATTTAATAAAATCAAAAGTCGTAGCGCTCATATGAAGACCCATCGTGTACCGGAGAATGaaacaactgtacaaaatgctaatcaaaatcaaacacatcaacaacaacaacaacaacaaGCTAATAACCACTAA
Protein Sequence: MATINSVPKSIHLPLAGLPATPRVLMCSASVGTEGSVTLKLRDANSSSSPSSDSNQSVSTVASNASNAVSSLDNALTIGYPDPEMLADVLGTLQTASLNNNNHYRSNGNECNSKVQINKLNTIVTTGAATPTTTAATATATTINSDNNPNNINTNHGNNQNNNVANTNNCINNIKNCANNLKSRVTISRRTSNVAHSSQTQKDSPKCTIAAAVQTVSISTNTTNKTNSYIKNCLIRSSSCNNTTNITSLAQIMSNSSSSNSNSNSNINSNSNSNSNNNNNNNNNNNNNSNSSSNNNNNASSTFQQFQSSSNSNLSCSNSNSNCSSNSNYSSNSNDSCFSITSSSNSSSGNISVRCAPIPCNRKVPVSLTNPPKILKKNRSKLSSPSRHGPQQCQICNKIFGNASALAKHKLTHSDERKYVCVMCSKAFKRQDHLNGHMMTHRNKKPYECKAEGCGKSYCDARSLRRHTENHHAGVITPQNQNLSSINVNCSSANLSLSPATANGDASSPDGATCLGTYLSNGGTVVDASTGLALTEDEVKALKTNVTLLSPTSTLSSSSSSASSIASTSTAATITLTDSGGNMEGEGLTPEQLDLISKIMRQTKQTTAQVTVSSHSSSQSYKIDTSPAQTQTQNPRPRTWNMQLLNTTQNLAITVDEVSNDAIPRNIDSPLLAMDAKEEEVKIDLTSGLNSSSLLNVVKIDQKPVECNLCHRKFKNTPALNGHMRLHGGYFKKDPETKKSEKKENNGPPLQTASIGVRALIEEKIINKRSRDINKGSFAVPAPPTNNLANNPILRRSISDLENFLSSKNQTSSGSCISSNLNTMSTPSVAFKNNNRTMLNAQDMGLPQSIEIFSTKQQKPMNNVSVGVGTNLTQLNSGECSSVTTTEKPVTTTLNTTTSTGTTTRSTSTDPKDSTLIELLKRGTRIAVTSKQASNAPLGGVTRQIVNTTTTTNSPSRAVLIPSDVQVINNKVKLATTTQEIENSLNNCPESTGISLAQSSPLSLTLSQNGDVNAEVYTVTYASDNSNLFEETEVYNVSEAEMLLQTVDTMQLLNDSNHENLLKSSEHSEQYEIIDNNGQVLQPSCPTDINNGSECKQQQILPNFQHFHSKELLMNPLTQSNGSLNSLSMPLVERKQLYGRLNSPLHSPLAYPTPPSSHENVTQTSPYVDDNQQYGETSNVFFSESLISNASTSATGEMENEKLTKLGNIMGDNNFDNNNIKMEDLLSDTNTDAERDLREFAEANLSFLDEEQEFLNDSGNAASPLSESFFSGGIGSVEEVKEVLREVLTEDQIQINCESQSENIIDLYYLPCLSLQSQMMPNSEDPLLSSSPRDFGQQKLTQTANNTSQHIPHQQQPNLNPNASTNTSQNPYLQSNNAAISVQLQQQQQQHQHQQQQQPPQQQQGVLKMQPLQTQQMPSEINQVIVTVPANGCGNTASIMQYNFQNTPQVQIPTNTQQYIDSANQSHTQASNSTSSNRTITAQLNEALTQPLVYTGTTERSEMKLMPTQNHNRLNLNIEQRQQETQQRLQITDVLNNSNIYYGQIASNEQQQTPQYCQTSNAMNSTSVLTTILQPLSNQTNSILKRRLRGYNSSDSGSSGYQLKFQTLSPYRSKLRKPSRTHYTPAPILNPARKGHGLYCNILKESNGNLSAFDAFDDDFEDSVGLVDFSDVSKVNLGSAYQAAIPIFKERSALTAIDEPVKAELMWNPDIQRDENILMRFIDLSKSSATPSGSHTEEIALKTLLKSHGNTASAVLTLLQTQSNPFQMKWSAQELETFLKGLEKYGKEFSKISKELGSKTTGECIQIYYFWKKLCVDYKVTHLKTETPPVNHSNEVKPYVCEQPDCSASFSSKAALHGHTRIHTYGRNSHNNNHSATNPNANNSLPGSISSTSACTASSQALSHSVNLVNKDNTTATNTKDINNDFPCKVCGKVFNKIKSRSAHMKTHRVPENETTVQNANQNQTHQQQQQQQANNH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00750397;
90% Identity: iTF_00749955;
80% Identity: iTF_00748912;