Basic Information

Insect: Glossina morsitans
Gene Symbol: L
Assembly: None
Location: scf7180000648122:122534-138672[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 4.9e-06 0.00027 20.7 1.7 1 23 222 244 222 244 0.98

2 19 0.39 21 5.3 5.7 1 23 250 272 250 272 0.98

3 19 2.1e-07 1.1e-05 25.0 3.1 1 23 278 300 278 300 0.99

4 19 9.7e-06 0.00053 19.8 0.3 1 23 306 328 306 328 0.98

5 19 0.58 32 4.8 1.0 2 23 393 416 392 416 0.90

6 19 0.0067 0.37 10.8 0.3 3 23 444 465 442 465 0.96

7 19 0.033 1.8 8.7 0.5 1 23 563 585 563 585 0.96

8 19 0.0024 0.13 12.2 0.8 2 23 593 614 592 614 0.96

9 19 2.2e-05 0.0012 18.7 0.9 1 23 622 646 622 646 0.93

10 19 0.13 7 6.8 0.0 1 19 651 669 651 671 0.96

11 19 8.4 4.6e+02 1.1 0.4 1 23 681 704 681 704 0.91

12 19 0.0013 0.069 13.1 2.9 1 23 743 765 743 766 0.96

13 19 2.8 1.5e+02 2.6 0.9 1 23 921 945 921 945 0.89

14 19 0.00092 0.05 13.6 4.6 2 23 954 976 953 976 0.96

15 19 0.11 5.8 7.1 0.1 1 23 982 1004 982 1004 0.92

16 19 0.26 14 5.8 0.3 2 20 1012 1030 1011 1033 0.93

17 19 3.6 2e+02 2.3 0.6 2 23 1124 1145 1124 1145 0.93

18 19 0.00043 0.024 14.6 0.1 1 23 1155 1177 1155 1177 0.97

19 19 0.0091 0.5 10.4 0.7 1 23 1184 1206 1184 1206 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	4.9e-06	0.00027	20.7	1.7	1	23	222	244	222	244	0.98
2	19	0.39	21	5.3	5.7	1	23	250	272	250	272	0.98
3	19	2.1e-07	1.1e-05	25.0	3.1	1	23	278	300	278	300	0.99
4	19	9.7e-06	0.00053	19.8	0.3	1	23	306	328	306	328	0.98
5	19	0.58	32	4.8	1.0	2	23	393	416	392	416	0.90
6	19	0.0067	0.37	10.8	0.3	3	23	444	465	442	465	0.96
7	19	0.033	1.8	8.7	0.5	1	23	563	585	563	585	0.96
8	19	0.0024	0.13	12.2	0.8	2	23	593	614	592	614	0.96
9	19	2.2e-05	0.0012	18.7	0.9	1	23	622	646	622	646	0.93
10	19	0.13	7	6.8	0.0	1	19	651	669	651	671	0.96
11	19	8.4	4.6e+02	1.1	0.4	1	23	681	704	681	704	0.91
12	19	0.0013	0.069	13.1	2.9	1	23	743	765	743	766	0.96
13	19	2.8	1.5e+02	2.6	0.9	1	23	921	945	921	945	0.89
14	19	0.00092	0.05	13.6	4.6	2	23	954	976	953	976	0.96
15	19	0.11	5.8	7.1	0.1	1	23	982	1004	982	1004	0.92
16	19	0.26	14	5.8	0.3	2	20	1012	1030	1011	1033	0.93
17	19	3.6	2e+02	2.3	0.6	2	23	1124	1145	1124	1145	0.93
18	19	0.00043	0.024	14.6	0.1	1	23	1155	1177	1155	1177	0.97
19	19	0.0091	0.5	10.4	0.7	1	23	1184	1206	1184	1206	0.95

Sequence Information

Coding Sequence: ATGATGGCTTTAAAAATGTTATATCGAGGACCCAGTTCAAGACTTGAAAACCTAATCGAAAAAATCCAAGCCACTAAGGAAATTGTTAATGCTGATATGTACTCTACGCACACTTCTTCCAGTTACTCGCCTTCAATATCGGATGGTACTCTTACACCGAATTCTTTACATCATCAGCATCTTGGTGTTGTTTCGCACCTAAACTCCATGTATTCACATAGCGAAGAAGATGCTGCCTTACAGACGCAACGTCTTTCTCAAACGCAAAAATCCAATGGTTGTTTAATGGATGGCGCTGACTATGAAGACAACGAGGAGAATTTACGCAAAAATAATGATACAAAGACAAACAATGATGGTACGCCAACTACAAATGCTGCCGACAATAATAATGGAGAACAACAACGCCAGCACCAACATTCCCATCATCAACAACTAAAACAGCGTCAGGGACGTCATCATCGTCATGCAGAGCATGTCATGAGAATTCCTACAAAATTACGAAAAATCGATAGGGATTCAGAAGTTTGCAGTGGTAGTGTTGGTGGCGTTGTTGGTGGTGGTACCACCGGCAGCGGTAACAGTAGCAGTAACAATGCCACTAAATTTGATAAGTTGACAGGCGATGGCATTAAGCACAGTGGCAATACGGCCGACGGATCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCACGTCTTGGTTACTTaaaaaaaCACGAGCAGAGTCATGCCGAACACTTGCCTTTTAAATGCGAATATTGCGCTCGCCTATTTAAGCATAAACGCTCACGGGATCGTCACACAAAATTACATACCGGAGATCGTCGTTATCGCTGTCCTCACTGTGAGGCAGCATTTTCCAGAAGCGATCATTTGAAAATTCATATGAAAACCCATGACAATCAGAAACCATTCCAGTGTACGATTTGTAATAGAGGTTATAATACGGCGGCCGCTCTCACTTCTCATATGCAAAATCATAAGAAACAAGCCGCTCTCTTAGCCGCCGGTGGCAATCCTCAAACTCTTAGCTATAGTCCTCGATCTACTGGGTCTGCGTCTAGTAATGGCAGTTTGCATAAACGCCGTTACAATCTCGCAATTGAACCGGAAAATAGTCCAAGTCGTTTGGATTTTCCCAAACGAGTGCGCTGTTCGTCGTCTAACTTTCTCAAGTGTACATTTTGTACTAAATCCGATTTTGTTAATATGGAACAACTGAACTCTCACATCCAGCGTATGCATGAGAAAGAGTTAATTAATACGATGCCTCAAGCTTCCACCAACACTACACTGCCTGCCGATGGTAACGCTTTCCAGTTGGCTTGCGAGTATTGCACTATGAAATTCCCAAATATACCGACAATGTTCCAGCATATGCGTTCCACTCATATCGATCGTCTTGCAAGCCCGAATTCCTATTTCGAGCATTTGAATCGTTTGGCAGCGTCAGGTACATTCAGTCCACGTTTACTTACTAACCCACCATTAAGAAGTTCTGCTAGCACCGAGGAGAATTCCATTAAGGAAGAAACTCAAACCAACAGTCCCAAGACCGTAGAAAATTCGGCAAAAACCAATGAAGATGAACCCACAGATCTAAGCCAAAATAATAGGCATCAGCACTCCCCGCCTGCTGCACTGCAGGATCCTCCTTCAACAGCCAGCGAAAAGCCGGGCGTCTACCTTTGCAATCAATGCAATGCCGGTTTACCAAATTTCGATAGTTTTCGTACTCATTTGCAGACTCACTTGGCCCAAAGTCTTAATTTAGTTTGTCATCATTGTGGCTTAGTACTGCGAGAGCTATCTGACTACGAAAGACATGTTATATCGCATTTCCTTATCACAAACTCCGAATACAATTGTCCGAGCAATTGTCAGAAGACTTTTACTAAATCGGATGATTTGCAAAAACATTTAATCGATCAGCATACAGTTACAGTCTACAAGTGCGGAATATGCTCGGATATATTTGACACTAAAGTTGCTTTGCAGGTTCATTTCGCCTGCACGCATGCGGAAGAAATTAAAATTTTTCGTTGCTCCGCTTGCATGGATGTCTTTCGCAATGAAAACGATTTCGGTGTACATGTGAAAACACGTCATCAGGCTGTCAACCCAAATCCAGCCCCTATTAACAATTTGCAATGCATGTTTTGTACGGCAGTGTGTTCATCGGATCTCGAAATGCAATTTCATTTGGCTGCGCATGCCCGACAATTCCGTTGCCCCTCGTGTCCGGAAACATTTCATGTTGAATTTCTTTTGGATAGACATATGCAAACGCATCATGGTGAACGTGTAGCCGTCGCTCAAAAGGACGGTTTCGATGAAAGTTCCACGTCCACATCGAGAAATAATAGCTTGGCGCCTATGAACTCTTTATATGTCAATGCTTTATTTGGTAAGGCACCGCTAGTGCCTTTGGCGACTCAAAATAATAACAACACAATTTTGGATTACAATATGGCTTTTGCTACGCATATTAATAAAGGTTTGTTCCCTAACGTTGCTGCCCAAAAGTTTTATAATCCTTTGCAAATCGATACGAATGCTATGAAACACTCAGCCTTAATGTACGGTTTAAGTCAACGTTACTTTGATACAAATCGCTCGGTAATAGATCTATATAATCAGAATCATGCCGAAAAGAATGCAATGGCGGGAAATTACTTCATTAGCCCGAAACAGCCAACAAATGCAGAAGTGCTTAACCGTCCCGAATTGTCGGCTTCACCGTTAACGTCTGCCGGTTTCAGTTGTGGTATATGTGAACGCAATGATTTCCGTACGGAATCTGAGGTACACTCACATCGTAAAATAGTTCATAATTTGAAAACTGGTGTCAGTTTACGTTGCGCTTATTGCTCGGGTAATTTTAAATCACGCAGTGAACTAGAACATCATATGAAAACCTGCCACAATTCCACTGGTAAACATAAATGTTTGATATGCGATGAAATCTTCCCCTCACCTGCCATATTGGCCGAGCATAAGTTGCAGCATTCAAAAGTGGGACAATCAGGCAAATGTTCACATTGTTCGAAAGTTTTGCCTGACGTAGCAGCGTTTAAGTCTCATCTACCCGAGCACAACAACGAAGGTCAAATGCCAGTACAATGCATATGCTGCCGGCAAACTCTGCATTCCGAGTTCGAGGTTGGATTGCACGCCAAATTCCATGTGAAGTCTTCACAAGTATCCGAGAGCGTTTGCGCTTTATGTTTAGAACCAATAGCACCTGGGTCTCCGACGGAGGCTAAAGTTTGCGAGAAATGTTGCCGTAAGCATAACCTGAACAATAAATTCAAGCAACCGGAAAACTTTGAACGGCCGTCCATACATCGACAATATGTTGAAAATCGATGCAACCTATGCAAAATGATTTTGCCTCATGTCCAAAAATTGCAAGAACACCTCGTGGAGCATACGTTCGCGGGCTGCGAAGATCGGGGATTTAATTGTTATATTTGCTCCGCGGTGTTTACGGTACCGAGCGGTTTACTTAATCACATGAACGATCACGGTTTGAATGCTCGTCCGTACGATTGCAATTTATGTCCAGAGAAATTCTATTTTCGAGCCGAACTTGATCATCATCTAATTGATCATGATGTACGTGATAAAGGTCCCATAAAAAATGAACTGGATCGACCTCTAATAAATGAAAATAAAAACGTTGCGACAAAAGGCTGTACAACGGCCAAGTCAGAAGTTCCTTTAAAGCTTACGGAGGTTAAACAAGAGATTATTGATGCCGAGGAAACAATTAATGCAAACGAAGATGATGAATATATTGAGGTAGAGAAAATCAATGAAACAACAACACTGGAGGTAAGAAAGCAAGAGAAGTCAGATTCGGAGAATTCCTCGGATGAGAAGTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEIVNADMYSTHTSSSYSPSISDGTLTPNSLHHQHLGVVSHLNSMYSHSEEDAALQTQRLSQTQKSNGCLMDGADYEDNEENLRKNNDTKTNNDGTPTTNAADNNNGEQQRQHQHSHHQQLKQRQGRHHRHAEHVMRIPTKLRKIDRDSEVCSGSVGGVVGGGTTGSGNSSSNNATKFDKLTGDGIKHSGNTADGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQAALLAAGGNPQTLSYSPRSTGSASSNGSLHKRRYNLAIEPENSPSRLDFPKRVRCSSSNFLKCTFCTKSDFVNMEQLNSHIQRMHEKELINTMPQASTNTTLPADGNAFQLACEYCTMKFPNIPTMFQHMRSTHIDRLASPNSYFEHLNRLAASGTFSPRLLTNPPLRSSASTEENSIKEETQTNSPKTVENSAKTNEDEPTDLSQNNRHQHSPPAALQDPPSTASEKPGVYLCNQCNAGLPNFDSFRTHLQTHLAQSLNLVCHHCGLVLRELSDYERHVISHFLITNSEYNCPSNCQKTFTKSDDLQKHLIDQHTVTVYKCGICSDIFDTKVALQVHFACTHAEEIKIFRCSACMDVFRNENDFGVHVKTRHQAVNPNPAPINNLQCMFCTAVCSSDLEMQFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHGERVAVAQKDGFDESSTSTSRNNSLAPMNSLYVNALFGKAPLVPLATQNNNNTILDYNMAFATHINKGLFPNVAAQKFYNPLQIDTNAMKHSALMYGLSQRYFDTNRSVIDLYNQNHAEKNAMAGNYFISPKQPTNAEVLNRPELSASPLTSAGFSCGICERNDFRTESEVHSHRKIVHNLKTGVSLRCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSKVLPDVAAFKSHLPEHNNEGQMPVQCICCRQTLHSEFEVGLHAKFHVKSSQVSESVCALCLEPIAPGSPTEAKVCEKCCRKHNLNNKFKQPENFERPSIHRQYVENRCNLCKMILPHVQKLQEHLVEHTFAGCEDRGFNCYICSAVFTVPSGLLNHMNDHGLNARPYDCNLCPEKFYFRAELDHHLIDHDVRDKGPIKNELDRPLINENKNVATKGCTTAKSEVPLKLTEVKQEIIDAEETINANEDDEYIEVEKINETTTLEVRKQEKSDSENSSDEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00746926;
90% Identity: iTF_00746926;
80% Identity: -