Basic Information

Insect: Glossina morsitans
Gene Symbol: -
Assembly: None
Location: scf7180000650874:45697-54004[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 1.8e-06 0.0001 22.1 0.8 3 23 212 232 211 232 0.98

2 22 4.3e-06 0.00023 20.9 0.5 1 23 336 358 336 358 0.94

3 22 0.0012 0.064 13.2 1.5 1 23 364 386 364 386 0.98

4 22 9.5e-06 0.00052 19.8 0.3 1 23 404 426 404 426 0.99

5 22 0.029 1.6 8.9 0.2 1 23 435 458 435 458 0.95

6 22 0.0014 0.077 13.0 4.8 1 23 464 486 464 486 0.98

7 22 0.00014 0.0079 16.1 0.3 2 23 493 514 492 514 0.97

8 22 2.2e-08 1.2e-06 28.1 0.7 1 23 520 542 520 542 0.96

9 22 0.008 0.44 10.6 0.9 1 23 548 570 548 570 0.98

10 22 0.00037 0.02 14.8 3.0 1 23 576 598 576 598 0.96

11 22 0.0016 0.089 12.8 3.3 1 23 777 800 777 800 0.97

12 22 0.59 32 4.7 5.1 2 23 864 885 863 885 0.96

13 22 0.00059 0.032 14.2 5.4 1 23 891 914 891 914 0.96

14 22 0.022 1.2 9.2 4.5 1 23 938 961 938 961 0.96

15 22 1.4e-05 0.00074 19.3 1.7 1 23 967 989 967 989 0.99

16 22 3.1e-06 0.00017 21.3 5.4 1 23 995 1017 995 1017 0.99

17 22 5.4e-08 2.9e-06 26.9 1.5 1 23 1023 1045 1023 1045 0.96

18 22 0.028 1.5 8.9 2.9 1 23 1051 1073 1051 1073 0.96

19 22 3e-05 0.0016 18.3 1.3 1 23 1079 1101 1079 1101 0.97

20 22 1.6e-06 8.5e-05 22.3 0.6 1 23 1107 1129 1107 1129 0.99

21 22 3.2e-07 1.7e-05 24.5 1.3 1 23 1135 1157 1135 1157 0.99

22 22 3.6e-05 0.0019 18.0 1.6 1 23 1163 1185 1163 1185 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	1.8e-06	0.0001	22.1	0.8	3	23	212	232	211	232	0.98
2	22	4.3e-06	0.00023	20.9	0.5	1	23	336	358	336	358	0.94
3	22	0.0012	0.064	13.2	1.5	1	23	364	386	364	386	0.98
4	22	9.5e-06	0.00052	19.8	0.3	1	23	404	426	404	426	0.99
5	22	0.029	1.6	8.9	0.2	1	23	435	458	435	458	0.95
6	22	0.0014	0.077	13.0	4.8	1	23	464	486	464	486	0.98
7	22	0.00014	0.0079	16.1	0.3	2	23	493	514	492	514	0.97
8	22	2.2e-08	1.2e-06	28.1	0.7	1	23	520	542	520	542	0.96
9	22	0.008	0.44	10.6	0.9	1	23	548	570	548	570	0.98
10	22	0.00037	0.02	14.8	3.0	1	23	576	598	576	598	0.96
11	22	0.0016	0.089	12.8	3.3	1	23	777	800	777	800	0.97
12	22	0.59	32	4.7	5.1	2	23	864	885	863	885	0.96
13	22	0.00059	0.032	14.2	5.4	1	23	891	914	891	914	0.96
14	22	0.022	1.2	9.2	4.5	1	23	938	961	938	961	0.96
15	22	1.4e-05	0.00074	19.3	1.7	1	23	967	989	967	989	0.99
16	22	3.1e-06	0.00017	21.3	5.4	1	23	995	1017	995	1017	0.99
17	22	5.4e-08	2.9e-06	26.9	1.5	1	23	1023	1045	1023	1045	0.96
18	22	0.028	1.5	8.9	2.9	1	23	1051	1073	1051	1073	0.96
19	22	3e-05	0.0016	18.3	1.3	1	23	1079	1101	1079	1101	0.97
20	22	1.6e-06	8.5e-05	22.3	0.6	1	23	1107	1129	1107	1129	0.99
21	22	3.2e-07	1.7e-05	24.5	1.3	1	23	1135	1157	1135	1157	0.99
22	22	3.6e-05	0.0019	18.0	1.6	1	23	1163	1185	1163	1185	0.97

Sequence Information

Coding Sequence: ATGGCTTTGGATTTTACATTAATGTGTCGCACTTGCTTGAGTGAAAATAATGTGTATCACAAATTACAAGATGCCCCCTTGGAAAACTATAAAATTTTGGAAATGTTAACAGCATTGGTGCCGCAGTTAAATATTGATAAAGAAGATCTTACTTTCCCGGTTTTAGTGTGTGACTCTTGTGTGGATCAACTGCTAAAAGCATTTAAATTTCAGCAACAATGCTTGCAAAGTAATAAAATTTTTATGACTCTGGTGGCAAATAATCCCAGCACTACCACCAACGCGGCTACTGGAGTAGTGGTTTTAAATTGTAACAAAATGAAAATGGAGGTAGAAGACGATATCCATTTGCCAGAGAACAATAACTTTAAAGTAGAAATGGATATTGGGGAAGAGGCGAAACAAGAAAATTTTCCAAGTGAGATGAATCCCCAAGAAATAGAGATGGTCCTAAATGCTAACAGTGTTGACTGGTTTCATAATAATGATAGCGTCGAAGACGATGCTTTTAGTGCTAAAGATATTTTAGACATTTCATCTAAAGATAAGGATACAAGTATCGAAACCATTGCTAGTAAACTTAGAGCTCTAGAACGAGCTAATCATAAGGATGCACAAACTGCGAAGCTATTATGTCCCCAGTGTCCGAAAACGTTTAAGACTCAAAAGCTTTTAAATAAACATATTGCTCGACATGCTAACAAACACCCCAAGATGAAACCAATTACAAGAAAAAAGAATAGCTTAGATAAGAAATTAAAATCGGACACAATTGGAGACGTTGAAAAAATTAGAATAAAAACGGATGCTGCTGACGATGCTGCGGCGAATATACTGGAGAAAGGTCAAGATGGGAAAGATGCAAAGAACCAAGAAAACGAAAATCCCACTAGTGAAAATGAAGTAAAATCAGAAATTTTACATGATGATGATAACAAGGATTTTATAGATACTGGCATTGGCGAGATAGAGAAACCGAACAGCAATAATCGTCGTAATGGTTGTTATCAATGTCAAGAATGTGGTAAAGTATTCGATCGCCCGTATCGTTTGAAACGCCATAGCGGGGTTCACTCTTTAGAGCGTCCTTATCAATGTGAACAATGCAAATATCGATTTTTAACCCAGGCTTTGTTGAAAGCCCATAAACAGATGCATGACAATGAAAAGAGAGGTATTCAAATTACCCACCCCACTCCTATTAATGGCTTCAAATGCCCCGATTGTCCTAGACGCTTTGAAAAGCAAGCCTCTATGGCGGCTCATCGGCAAACACATACGCGTAATGCTGGTTTGGCCAGTTATCCATGTCCGGCTTGTGAACGCAAGTTCATGAAAATTCGCTCTTTGGCAGAACACATGTCAAATAAACATCCGGAAATAGAAAAACACCAGTGTAATCAATGTGAGAAATCATTTGTTCTACATGCTCATCTAGTTGAGCATCTAAATCGACATATGGGTAACAAAAATCTTGTTTGCCTGGTATGTGAGAAAGAATTTAGTTATGGCAATACCCTAAAGGAGCATATGCGTACGCACAGCGGTGAAAGCCCTTACTTATGTCCCCAGTGCGGTAAAACTTTTCGCAGTGCTAGTAATTTACGTCAACATATGGAACGTCATGGTAATGAGAAACGTTATCAGTGCCCAGAATGCCCAAGTCGTTTTGCCTGCCAATCGGATCGCATTAAACACATGTCGATACACACTAATCACAAACCACACGTCTGTGATTTATGTGGTTCAAGATTTACACGCTCCTACTCTTTGTCCAAACACAAACAATTACATACCGGCGAAAGGCCCCACAAATGTGACCAATGTAATATGGCAGCTCAAACATATTACAGTTTACACGATACAATTGTCCGTATAAAGGATGACGAGAATCTATCATTACAAGTGATGCTAGAACAAATTATAATAGATTGTAAAACGTTGCCGGAAGATTTAAAGATGCCGGAAGAAATTTGTGAGTTATGTATGGAGCAATTAAAAATCTCCTTCAAATTTCAACAGCTTTACAGACATACAAATGAGCAACTGTTGAGAATATGGGAACAAATGCGAACTTCTTCAATTACAGTTAGCGATGGTATCGAAAATGTTAAAAGCCAAGAAACTGGAACTGATTTAATTGAAGAAGAGTTTCGGCAAATTCAACAATCAAAAAATATTATATTTGATATAAATTCTCATAATTCAAGTATGGAATGTAATATAACGCATTCTGGGCACAATGGCTATCTTAATTGTAATGTTGTTACAGTTACTAAAACTCATCAATTTTTCAGGCATAACAAACAGCCATCATTAGAGAATAATTTTGTATGTAAAATTTGTTTCTACCGTTGTACCACAAACACTCTGCTTGAGGAACACGTGCGAAAAACTCATCAACCAAGGATTTTATTGAAAATAATAGATTTGAAAAGATTTTGGAATAAAGAATTATTGGAAGAGCAACGTGAGGGAATACCAAGTATAATTAGTGAAAATGTGGAAAGCTCGGAAAAGTTGTCAGGAAGTAATGAATCAGACAATAACGATACGAACGATTATTTGAGATCATGTAAACCATTACTTTCATGTACCGAATGCAGAGCTACGTTTAAAACTGCAAAACGTTTAAAGTGCCATaaaaaaaCTCACGTGAAATGCTATCGTTTCGTTTGTCACGTATGTGATCATCGATTTAAATTTCCTCATCTTTTAAAACAACATCTGATCAAAGTTCATGCGCAATTCCCTAATAGTAAAAATAGTAATGGATCAGTTGATAAATTAACGGTTGAGAAGCAAGTGCAATTCCATTGCAATTACTGCAAATGTGCTTATAATTCGGTAGGCAGTTTGGCACAGCACATGAGTAAGAAACATCCGACCATAAAACCATTCaaatgcgataaatgcgataaaGCGTTTGTAGTGGAAGAACACTTTAAAATCCATATAAATCGTCATAATGGCATAAAAAATTTCAAATGCGAGCATTGCGATAAATCATTTTCTTTTAAATTTGCGATGAAACAGCATATGCGTATGCATACAGAACCAGCACCTTATTTATGCACGCTGTGCGGTAAAACTTTTTATCGTCCCAGTAATTTACGTCAACACATGCAACGGCACGGCGAAGATAAACCTTACGCCTGCCCGCATTGTCCTAGACGTTTCAAATGCCCTTCAGATCGTTACATACACTTAATGTCGCATAATGCGGGTAAAGTGCATGTTTGCTCAATATGCGGTAGTCGTTTTTCACGTCTCGATACCCTAAACAATCATCAGATGTTACATTCCGGCAAAAAGCCCTACAAATGCGATCAATGTTCTATGGCCTTTGCTTCTCCAGTTAATCTAAATCGTCACAAACGCACTCATACTGGGGAAAAACCGTATAAGTGTCAATATTGCGATCGTGCTTATGCTCAAAGCAATGATTTAACCAAACATTTGCGGACGCATTTGGGCGAAAAAGTGTATATTTGCAATAAATGCCCGGAAGCCTTTAAATATCATGCAGAATTGAAAAAACATCAACTGCAACATTACCATGAAGAACAAGAATTACAAATATCAGCAAATTCCACCGATATAAAATGTGATGTTGAAAAATGTTGA
Protein Sequence: MALDFTLMCRTCLSENNVYHKLQDAPLENYKILEMLTALVPQLNIDKEDLTFPVLVCDSCVDQLLKAFKFQQQCLQSNKIFMTLVANNPSTTTNAATGVVVLNCNKMKMEVEDDIHLPENNNFKVEMDIGEEAKQENFPSEMNPQEIEMVLNANSVDWFHNNDSVEDDAFSAKDILDISSKDKDTSIETIASKLRALERANHKDAQTAKLLCPQCPKTFKTQKLLNKHIARHANKHPKMKPITRKKNSLDKKLKSDTIGDVEKIRIKTDAADDAAANILEKGQDGKDAKNQENENPTSENEVKSEILHDDDNKDFIDTGIGEIEKPNSNNRRNGCYQCQECGKVFDRPYRLKRHSGVHSLERPYQCEQCKYRFLTQALLKAHKQMHDNEKRGIQITHPTPINGFKCPDCPRRFEKQASMAAHRQTHTRNAGLASYPCPACERKFMKIRSLAEHMSNKHPEIEKHQCNQCEKSFVLHAHLVEHLNRHMGNKNLVCLVCEKEFSYGNTLKEHMRTHSGESPYLCPQCGKTFRSASNLRQHMERHGNEKRYQCPECPSRFACQSDRIKHMSIHTNHKPHVCDLCGSRFTRSYSLSKHKQLHTGERPHKCDQCNMAAQTYYSLHDTIVRIKDDENLSLQVMLEQIIIDCKTLPEDLKMPEEICELCMEQLKISFKFQQLYRHTNEQLLRIWEQMRTSSITVSDGIENVKSQETGTDLIEEEFRQIQQSKNIIFDINSHNSSMECNITHSGHNGYLNCNVVTVTKTHQFFRHNKQPSLENNFVCKICFYRCTTNTLLEEHVRKTHQPRILLKIIDLKRFWNKELLEEQREGIPSIISENVESSEKLSGSNESDNNDTNDYLRSCKPLLSCTECRATFKTAKRLKCHKKTHVKCYRFVCHVCDHRFKFPHLLKQHLIKVHAQFPNSKNSNGSVDKLTVEKQVQFHCNYCKCAYNSVGSLAQHMSKKHPTIKPFKCDKCDKAFVVEEHFKIHINRHNGIKNFKCEHCDKSFSFKFAMKQHMRMHTEPAPYLCTLCGKTFYRPSNLRQHMQRHGEDKPYACPHCPRRFKCPSDRYIHLMSHNAGKVHVCSICGSRFSRLDTLNNHQMLHSGKKPYKCDQCSMAFASPVNLNRHKRTHTGEKPYKCQYCDRAYAQSNDLTKHLRTHLGEKVYICNKCPEAFKYHAELKKHQLQHYHEEQELQISANSTDIKCDVEKC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00746872;
90% Identity: iTF_00746872;
80% Identity: -