Basic Information

Insect: Glossina brevipalpis
Gene Symbol: -
Assembly: GCA_000671755.1
Location: Scaffold24:419768-424449[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0013 0.081 13.1 0.0 1 23 130 153 130 153 0.97

2 14 0.00054 0.033 14.4 2.8 2 23 202 224 198 224 0.94

3 14 0.0073 0.44 10.8 0.5 1 23 349 372 349 372 0.90

4 14 0.46 28 5.1 0.4 2 23 421 443 420 443 0.90

5 14 0.017 1 9.7 0.1 1 23 504 527 504 527 0.88

6 14 7.9 4.8e+02 1.2 0.0 2 14 546 558 545 562 0.82

7 14 0.00058 0.035 14.3 1.5 2 23 578 600 578 600 0.97

8 14 0.0001 0.0062 16.6 1.1 1 23 691 714 691 714 0.96

9 14 1.5e-05 0.00094 19.2 0.1 1 23 772 795 772 795 0.95

10 14 0.041 2.5 8.5 2.7 2 23 845 867 844 867 0.95

11 14 0.06 3.7 7.9 0.8 1 23 939 962 939 962 0.92

12 14 0.36 22 5.5 0.8 1 20 1014 1033 1014 1035 0.94

13 14 0.003 0.18 12.0 0.1 3 23 1121 1142 1119 1142 0.95

14 14 0.81 50 4.4 3.8 2 23 1192 1214 1191 1214 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0013	0.081	13.1	0.0	1	23	130	153	130	153	0.97
2	14	0.00054	0.033	14.4	2.8	2	23	202	224	198	224	0.94
3	14	0.0073	0.44	10.8	0.5	1	23	349	372	349	372	0.90
4	14	0.46	28	5.1	0.4	2	23	421	443	420	443	0.90
5	14	0.017	1	9.7	0.1	1	23	504	527	504	527	0.88
6	14	7.9	4.8e+02	1.2	0.0	2	14	546	558	545	562	0.82
7	14	0.00058	0.035	14.3	1.5	2	23	578	600	578	600	0.97
8	14	0.0001	0.0062	16.6	1.1	1	23	691	714	691	714	0.96
9	14	1.5e-05	0.00094	19.2	0.1	1	23	772	795	772	795	0.95
10	14	0.041	2.5	8.5	2.7	2	23	845	867	844	867	0.95
11	14	0.06	3.7	7.9	0.8	1	23	939	962	939	962	0.92
12	14	0.36	22	5.5	0.8	1	20	1014	1033	1014	1035	0.94
13	14	0.003	0.18	12.0	0.1	3	23	1121	1142	1119	1142	0.95
14	14	0.81	50	4.4	3.8	2	23	1192	1214	1191	1214	0.94

Sequence Information

Coding Sequence: ATGGATGAACTCGAACCTTGGCATCTTTTTACCAATGATTTTATGCCCGATGTATCAAATAATGCGAATCAAGAACAAAATTCATATAACGATCCAACGCCCAATCTTCCAAATATGCAGGTAAAAGAGGAGCCCGTAGAATCTTTAGATATTATTAATGATGATCAAAGCTCCTCCTATGGTTATATGAATCATTCATCATTTAGTAATACTCAGTGTCAACAATATGAGCGTTGTGATGACGATAACACAATATTTGATTTTGGACTTGATTCGTCTTCAGGTGGCAAGGATTCGACTGTCAAAACTTCTTCTAATGATTTCAAACCTTTGTCTGCTGAAGATCAATATTATCATTCGCTTATTAAATTTGAGGATGCAATTGTTTATATATGCCCAGCCTGCGGTCAAGAATTCAAAGCTCAGGAGTTATGGAAACGTCATTTGAATGTAATCCATCGTTACAATACGCGCAATGGCCTAAATTTTATGCAATTAGATAAATTATATCATCAATGCATGGAGTGTAATAAGCGTATTGCCATGCACAGCATGGAAAATTTATTAAAACACAAATTTACTCATCTGCCTTATAGATGCAGTAAATGTAGCATTTGCCAACGTCAGTACAAGTATCGGCAAGATTTGATGGTGCATATACGGATGATGCATCGAGATGATTTATTAGCTGCTATCAAAGCCGAACATCAAAACAAACCGAAAACGAGTTTAACTGTAAAAGCTGAAGGTAATAACAATAGCAGTAAACCATGTTTAACTATAGGTGACGTGAAAGAGAATGCTTTCGAAATTTTTGACAATACTGTGGATAGTAACATCGAAGTGAAGAACGAGTTTATTGACCCTAATGAAGTCGATGATGATCAGGTATCGCTTACTAAAAAGCCGGCAATCAAATCATCTACATCTGCTTTAGCTGCTTTGTTGGACGAAGGTTCCTCCAATGGTTCAGCAGCTGAAGAAAAGCCTCTTAATCAAGCAAATGTCAATGTTGACGATGATTCTCTAGAAGAATATATATTGTTTTTGTGCCCTCAATGCGGCACCGAATGTGAAACCCAAGCTCAGTGGCGTCAACATATTGAATTCGTTCATGATTTTGGTTCTTATAAAGCCTTAAACTTCAAGGAATTAAATTCTCAAGCACAGTGTGTAGAATGCAATCAGATTATCCCTTCCATTGCTTTACGTAATTTGCAGGTGCATAAATTCACTCATTTACCGCACAAAGAGTGGTTGACCTGTAAGTTATGTTTTGCAACGTATTCCGTACAAAAGGATATAATCAAGCACTTGGACGATAAGCATCATCTACAGGGGGAGAATTCGAAATGCGTAAGCGCTACTACGAATAATGCAGCTTCCATGCATAACGAAGAAGACAGCCAAGACTTCGAAGACTATGATAGTGGTATGGGAGCAGCGGATGTTAAGGAAATTCAACGTTCAAAAAGTGACGAACGTGATGCTTTCGAACAGCATATCGATTATTTGTGCCCTCAGTGCGGTAAAGAGTATAATGATaaaaaaaTATGGCGCAAGCATATTGCCGACGTTCATCAATTGGCCGATTTAGAGAAATTAAATTTTGAAGTCCTTAATGATCGTCAGCTACGATGTCGCGAATGTGACAAGATTATAACAAATGCTTACGGTATACAAAATGCTCAACAGCATCGCATTACTCATATGCGATTCAAATCTTTTGCTCGGTGCCGTTTATGTCGAAAAGCGTATACTGATCGCAAAGGTTTAATTAAGCATTTGCGTAGCTCACATCGCGTTGGTATGCGGGGTGTGCCGATACGCATGTTATCGCCTTCGCCCATGGCGATTACAAGCAATAGTTTTCTGCGTTCGGGTACTAAGATTAAATCATATCATAAATCCTATGGACAAAAGGAAGTAGTACGTTTGGCCGAAGGTACCTATGAAATACACTATTTAGACGAAGATGACGACGACTTGGGTAATGCTGACGAAGAATTTGGTGAGAATGCCGACAAAAAATATTCCCCTAATAATCATCAACTAGAGCAAATGACGAGACACAGGTGTGTGGATTGTGGCTCACAGTTCTCGACGCAGAATGCTTTACAAAATCACATTAAAAATGAACATGACTTCATGGAGTTCGACAATTCGCCCAGTGAGCACAAGCCGCAAATAGCAGCGTCAGCAGCCGGTAACGACGATGACCAATCAAATGACACAGATGCCGATTTACTTGTGCCAACTGGTGATGTTGATATACGACCCGAGGAAAATACCAGTATTGAAATCAATTTTATTTATTTATGCCCACAGTGCGGCGAGGAATTCCGCACTCAAGCTCTATGGCGTCGTCATATCAATGTCGAGCATAATTTCGATAAACGTGAGTATCTTGGCTTTCGCCCAGTTGACAGATTTCGTTATCAATGCAAAATGTGCAAGGATACCGTGCAATGTTCTAAATTGAAGGGCTTGCAAGATCATAAATTTCGTCATTGCCCATATAAATTATATTTGAAATGTCTATTGTGTAGTACTAGTTACAATCATAAACCCAATATGCTAACGCACTTACGACAGCGACACAATATTATTGAGGCCTATGAATTTGGTGCAAATAACCAAAGTGGCAACAATTCTGCTACCGGTTACGAAGAGCTAAGTTCCTCATCAACGAAGATTGGACGAAAAGTCAATGAAAATAGCAGTGCGAATAACAACGGCTCTCGCCCACCAGGTTTAAGAACTGTAGAAGATGTTATTTCATTTCATAATGCTGTCGATCACGATACTATCACATATTATTGTCCATCATGCTATGAAAATTTTGAATCGCATGTCTATTGGCGTAAACACATAGTTGAGGTGCACAATCTTAATAGTCGAGAAGGCTTGAATTTCCGCCAGTTAGATGAACATCACTATATATGCTTACAGTGTTATAAGCGTGTAACTGTTACTCATACTAAGGGAGCTATCGGCCAGTTGCAGTCTCATAAATTCCGGCATTTGCCTTACAAATCATTCCGTTGCACTGCCTGTCAAGGAGAATTTGTTCGAAAACAAATGTTCTTTAAGCACTTGGATAAAAATACCAATAAATGCAATGGTGTTAATCCAAATGAAAACGCTTCCGATGAATTCTCTAGTGGCAAAGCGCAAGAAACCAGCCAACAGCATTCAGAGCAGTTTGATGATGATTTGGATTTGAGTGGCGCGTTAGTTCAGCGTAATGGAGCTGATTTTGGTAACAGCAATATGTCTTGGCCGTCGCGCGATACCGGGGCTGGCAGTAGCAGCAGTGTTAATTCATATAACGATACTGTTAGTTGTTTTACCATAAATTGTCCACAATGTGGCATTAAATTTGATACAACGCAAACTTGGCGGGAACATATTAACATTGAACATCAACTTAACAATCGTACGGTACTAAATTTTAAAAGAATCTCACCCAAGCTTCATCAATGTTTGGAGTGCAAAGAACATGTTAATGGTCGGAAGTTGCGCGACTTACAAGTACACAAATTCAAACACCTACCGCACGGCGCTTACATACACTGTCGCTACTGTTCCATGGCTTATTTCCATATAAGTAACATGCAGGAGCATTTGAAAAATAAACATCCGCAGATGTTAAATAAAATGTATTCGACAGACACGCGTCGTTACGACGAAGAGAACATTATGATAGAGGGTGAGGATGAAGAGGATGCAGACGAAAATCCCGAAGTGGACGAAGAGGAGGGTGATATATTGTATGGAGAAGAAATTGATCCTGCCGATCTGTTAGAAGCCGAAGCTGAAATTGAAGAGGTCGATCCTGATGCCGCCGAATCAGAAGAACAATATCTATTAGGTTAA
Protein Sequence: MDELEPWHLFTNDFMPDVSNNANQEQNSYNDPTPNLPNMQVKEEPVESLDIINDDQSSSYGYMNHSSFSNTQCQQYERCDDDNTIFDFGLDSSSGGKDSTVKTSSNDFKPLSAEDQYYHSLIKFEDAIVYICPACGQEFKAQELWKRHLNVIHRYNTRNGLNFMQLDKLYHQCMECNKRIAMHSMENLLKHKFTHLPYRCSKCSICQRQYKYRQDLMVHIRMMHRDDLLAAIKAEHQNKPKTSLTVKAEGNNNSSKPCLTIGDVKENAFEIFDNTVDSNIEVKNEFIDPNEVDDDQVSLTKKPAIKSSTSALAALLDEGSSNGSAAEEKPLNQANVNVDDDSLEEYILFLCPQCGTECETQAQWRQHIEFVHDFGSYKALNFKELNSQAQCVECNQIIPSIALRNLQVHKFTHLPHKEWLTCKLCFATYSVQKDIIKHLDDKHHLQGENSKCVSATTNNAASMHNEEDSQDFEDYDSGMGAADVKEIQRSKSDERDAFEQHIDYLCPQCGKEYNDKKIWRKHIADVHQLADLEKLNFEVLNDRQLRCRECDKIITNAYGIQNAQQHRITHMRFKSFARCRLCRKAYTDRKGLIKHLRSSHRVGMRGVPIRMLSPSPMAITSNSFLRSGTKIKSYHKSYGQKEVVRLAEGTYEIHYLDEDDDDLGNADEEFGENADKKYSPNNHQLEQMTRHRCVDCGSQFSTQNALQNHIKNEHDFMEFDNSPSEHKPQIAASAAGNDDDQSNDTDADLLVPTGDVDIRPEENTSIEINFIYLCPQCGEEFRTQALWRRHINVEHNFDKREYLGFRPVDRFRYQCKMCKDTVQCSKLKGLQDHKFRHCPYKLYLKCLLCSTSYNHKPNMLTHLRQRHNIIEAYEFGANNQSGNNSATGYEELSSSSTKIGRKVNENSSANNNGSRPPGLRTVEDVISFHNAVDHDTITYYCPSCYENFESHVYWRKHIVEVHNLNSREGLNFRQLDEHHYICLQCYKRVTVTHTKGAIGQLQSHKFRHLPYKSFRCTACQGEFVRKQMFFKHLDKNTNKCNGVNPNENASDEFSSGKAQETSQQHSEQFDDDLDLSGALVQRNGADFGNSNMSWPSRDTGAGSSSSVNSYNDTVSCFTINCPQCGIKFDTTQTWREHINIEHQLNNRTVLNFKRISPKLHQCLECKEHVNGRKLRDLQVHKFKHLPHGAYIHCRYCSMAYFHISNMQEHLKNKHPQMLNKMYSTDTRRYDEENIMIEGEDEEDADENPEVDEEEGDILYGEEIDPADLLEAEAEIEEVDPDAAESEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00748518; iTF_00749233; iTF_00746997; iTF_00749978; iTF_00750752;
90% Identity: iTF_00750752;
80% Identity: -