Basic Information

Insect: Glossina brevipalpis
Gene Symbol: -
Assembly: GCA_000671755.1
Location: Scaffold2:946221-952020[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0028 0.17 12.1 0.3 3 23 33 53 31 53 0.96

2 16 0.0047 0.28 11.4 3.1 1 23 59 82 59 82 0.96

3 16 0.15 9.3 6.6 0.4 3 23 87 109 85 109 0.89

4 16 0.0046 0.28 11.4 0.2 1 22 117 138 117 138 0.95

5 16 8.4e-06 0.00051 20.1 2.0 1 23 146 168 146 168 0.97

6 16 0.00018 0.011 15.9 3.2 1 23 174 196 174 196 0.98

7 16 1.8e-05 0.0011 19.0 3.9 1 23 202 224 202 224 0.96

8 16 3.1 1.9e+02 2.5 0.4 2 23 654 676 653 676 0.93

9 16 0.29 18 5.8 1.2 1 23 700 722 700 722 0.88

10 16 1.4 86 3.6 3.7 1 23 730 754 730 754 0.91

11 16 3.1 1.9e+02 2.5 1.1 3 23 760 781 760 781 0.92

12 16 0.0084 0.51 10.6 0.3 1 21 796 816 796 817 0.94

13 16 0.00015 0.009 16.1 0.9 1 23 825 847 825 847 0.98

14 16 1e-05 0.00062 19.8 1.9 1 23 853 876 853 876 0.97

15 16 3.2e-05 0.002 18.2 1.2 1 23 882 904 882 904 0.98

16 16 0.0011 0.066 13.4 1.1 1 21 910 930 910 931 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0028	0.17	12.1	0.3	3	23	33	53	31	53	0.96
2	16	0.0047	0.28	11.4	3.1	1	23	59	82	59	82	0.96
3	16	0.15	9.3	6.6	0.4	3	23	87	109	85	109	0.89
4	16	0.0046	0.28	11.4	0.2	1	22	117	138	117	138	0.95
5	16	8.4e-06	0.00051	20.1	2.0	1	23	146	168	146	168	0.97
6	16	0.00018	0.011	15.9	3.2	1	23	174	196	174	196	0.98
7	16	1.8e-05	0.0011	19.0	3.9	1	23	202	224	202	224	0.96
8	16	3.1	1.9e+02	2.5	0.4	2	23	654	676	653	676	0.93
9	16	0.29	18	5.8	1.2	1	23	700	722	700	722	0.88
10	16	1.4	86	3.6	3.7	1	23	730	754	730	754	0.91
11	16	3.1	1.9e+02	2.5	1.1	3	23	760	781	760	781	0.92
12	16	0.0084	0.51	10.6	0.3	1	21	796	816	796	817	0.94
13	16	0.00015	0.009	16.1	0.9	1	23	825	847	825	847	0.98
14	16	1e-05	0.00062	19.8	1.9	1	23	853	876	853	876	0.97
15	16	3.2e-05	0.002	18.2	1.2	1	23	882	904	882	904	0.98
16	16	0.0011	0.066	13.4	1.1	1	21	910	930	910	931	0.92

Sequence Information

Coding Sequence: ATGAGTAATTCCGCACTTGCCAACGCATCTATTGTCTCGGAAACTCAACCAATGCTAGTGAAACTCTCTACTGGTGATGGTATCCCAAAACTTTTTTGTCCCATTTGCAATAAAGCCTTGACATCCTTAAATGGTTATGTGAAACATGTTAAAAAACATGAATCACCTGGTGGCtttttttGTCGTTATTGTGAAGCACGCTTTTGCACGGATGAAGATTTAAAAAGGCATCGTGATACGGTTCATGTGACGATTGCATGTCGCCTCTGCAAAAATACAACATTTACTAACGAAGAAGAATATCGAACTCACATACGTGATGTACATAAAGGAGTTGATCGCGAATTATTCAAATGTGATAAATGTGGAGCCGAATATAAGACAATTGATCCATATCGCCGGCATATATCTACTGAATGCGGTACTAAAAAACCATACAAATGTGAACAGTGTTCAATGACGTTCGTAACTAAATATAATCTGAAACAACATATAGAATTTCATACAGGCGAATTGAAATACTGTTGCAGTTATTGTGGTAAAAATTTCTATCAAAAGGGACGTTTAGTAGAGCATGAAAGATCACATACTGGAGAGAAGCCTTATAAATGCGATGTTTGCGGCAAATGTTTTTCGCATCGTGAGAGTTTAGTTACCCATTCAACAGTGCACACAGGTATACGTTTGGTAGAATGCAGATGTTGCCAATCTCGTTTCTCCTGTTATTCTAATCTCATTAAACATCGCCGTACACGACCTGATACTTGCGGCCTTCCCGATTATGATCCACCAAAAAATCGTGTTCGCAAATTTACTTCGAGAATTCCCGCAACACTTAATCCCACCTCGGAAATAAAAGTCAGTAATGTTAACAAAATTATTAAACCCGATGATCAAGAGAAAATTGCTTCCCAAAAGAAAGAGAACGATTGCAAACCTAAAACCAAATTAATAGGGAGAAATCGTAAAGAAGGCCTAAGTAAAAGAGTCGCCAGAAAACCTAAACTTAGCGATGACACTGAAAATGTAGAGTCTTCAGATGCAACCGAAGAAGAAGAAGACAATGATGCGGAAAAATCAAACAAAGCATTAAGACCTAAATTaaaaaaaCATTGCACTATAAAACCGAAATGTTCtgatggtgatgatgataatgatgatgctgatgatgatgacgacgatatggtagattttcaacctgacgaaactgacgaggacgaagataatACGGACTTTAAATTACCCACCCCTGCAGCAACTAAACCTGAAATTAAGAAAGAAACTTTAGAAGAAGAACTGAACAATACAATAACGTTGCAAGTTCAACCTTTCGAAGATTTTCAGTATTCAGCTACAACAAATAGCGTGAATGTTAAATCAGAAGATGAAGAAGaaaaaaaTAGAATGTTAGAATGTTTAAATTTTTTAAATGAATGCGATTACCCAATACTAGATGATGATGTTCCTTTGAAAAATTATCAGaaaaaaaaGGTACCTTTAAAATTTCAACTGACCGAAAATGTTATAGATGATATTTTAGAAGAAACCGAATTAATATTGATTAAAGATGAAGAAGGTAATCAAGATGCAACATCTTTTGAAGAAGATGTATTAGAAGTCAAACCGACTGTTTCGATCGATGAAACTCACGCTTGTAAAGTCCTCTTAGAAGATGTTATCAAATATTATCCTCAACTTAAAGGTACTAAAACGGTCAAATTGTCTCGCAATGCTTTTAAAGCAGGACCAAAATGTAAAAAATTAGCAAAATCCACAAAGTCCTGTACTCCTGTTCCAAACAAATATAAAACAAAACGAATCCGTCAAACTAATTACAATTCTTTAGaaaacgataccaatgaaaaagaacaaaaaaggaaaacatttcgtttatcaaaaatatctcaaaaagaacttaaagaacGTCTTAAGATGGCCAAAAAACAAGAGAAAAGTTGGCAATGTTTATATTGTATTAAAATTTATTATATGCGTAAGCCGTATGAAAAGCATTTGCGCGATGATCATAAACGATCTGAAGAAGAAATACGAGAAATATTTAAATCGGAAGATACGGCTTTATCCAGTGAGGATGTATTCAAATGTCATATATGCGAGAAAATTTATTTGATGGAGAAACGCTTAGTTGATCATATTGAAAAACATGGACCCGATGGTAATTTAATACATAAGTGCCCTTGTTATTGTAGCTTATACTTTGCAACTCGTGAAGAAGCCATTAAACATGCGCATCAAATTCATAAAGATTTATTATGGTGTGAGATTTGTCAAAAATTCATGACCGGGTGTGATGCTTTGAAATCTCATAATGCTCGCGTGCACGGCCAGACTATGAAAGAATCCCAAATTAATAGTAAAAGGAATTTTGTATGCGATAAATGTGGAAGAAAATTTTTAGGCCGTACACAACTAACTGATCATGTACGATCGGATTGCGGTCGTCTACCAATATATCAATGTCAGGAATGTGGCAAATGTCTTACTACGGCTGGGATATTAAAAACTCATATGTTATTACATAAGGCAGATAGACCATATCAATGTGATCAATGTGGTAAAACGTTTAAAATTAAGGCTCAATACAAGGCGCATCTTAAGTACCGACATTCGGATGAGAAACATTTCAAATGTCACCTTTGCCCCAAAGCCTATCCTTATCGTGAAAGTTTATTAACTCATATGACGGTGCATACGGGTATTAAACGTTTCCTCTGCAATGGTTGTGGAAAACGTTTTACTTGTGTCTCGAATTTGCAAGCACATCGCAAAGTTCAGGCAGACACCTGTGGCTTGTTACCATTAAATGCCAAAGCTACCCAATATATGGGTGTTCAGAAAGGTAATTTATTAATGGGAGCGAAACCAGAAGCTGGTTTAGATTATATAGAAACTAACACTTTGGTGGCAAAAGATGTATTAAATCAAGATCAACCGATGGCTCAGGAATTAAATAATGGACCATCGGATAGTTCCTTACCGTTGGCGACTGCCCCGTTACATTATGCACATTCAACACCACCAGCACTGATAATGCCTACTTTAATAATTCAAGATTCTCATCAAGCATGGAATAATTACAATTAA
Protein Sequence: MSNSALANASIVSETQPMLVKLSTGDGIPKLFCPICNKALTSLNGYVKHVKKHESPGGFFCRYCEARFCTDEDLKRHRDTVHVTIACRLCKNTTFTNEEEYRTHIRDVHKGVDRELFKCDKCGAEYKTIDPYRRHISTECGTKKPYKCEQCSMTFVTKYNLKQHIEFHTGELKYCCSYCGKNFYQKGRLVEHERSHTGEKPYKCDVCGKCFSHRESLVTHSTVHTGIRLVECRCCQSRFSCYSNLIKHRRTRPDTCGLPDYDPPKNRVRKFTSRIPATLNPTSEIKVSNVNKIIKPDDQEKIASQKKENDCKPKTKLIGRNRKEGLSKRVARKPKLSDDTENVESSDATEEEEDNDAEKSNKALRPKLKKHCTIKPKCSDGDDDNDDADDDDDDMVDFQPDETDEDEDNTDFKLPTPAATKPEIKKETLEEELNNTITLQVQPFEDFQYSATTNSVNVKSEDEEEKNRMLECLNFLNECDYPILDDDVPLKNYQKKKVPLKFQLTENVIDDILEETELILIKDEEGNQDATSFEEDVLEVKPTVSIDETHACKVLLEDVIKYYPQLKGTKTVKLSRNAFKAGPKCKKLAKSTKSCTPVPNKYKTKRIRQTNYNSLENDTNEKEQKRKTFRLSKISQKELKERLKMAKKQEKSWQCLYCIKIYYMRKPYEKHLRDDHKRSEEEIREIFKSEDTALSSEDVFKCHICEKIYLMEKRLVDHIEKHGPDGNLIHKCPCYCSLYFATREEAIKHAHQIHKDLLWCEICQKFMTGCDALKSHNARVHGQTMKESQINSKRNFVCDKCGRKFLGRTQLTDHVRSDCGRLPIYQCQECGKCLTTAGILKTHMLLHKADRPYQCDQCGKTFKIKAQYKAHLKYRHSDEKHFKCHLCPKAYPYRESLLTHMTVHTGIKRFLCNGCGKRFTCVSNLQAHRKVQADTCGLLPLNAKATQYMGVQKGNLLMGAKPEAGLDYIETNTLVAKDVLNQDQPMAQELNNGPSDSSLPLATAPLHYAHSTPPALIMPTLIIQDSHQAWNNYN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00746921; iTF_00749163; iTF_00749900; iTF_00748436; iTF_00750686;
90% Identity: -
80% Identity: -