Basic Information

Insect: Glossina austeni
Gene Symbol: -
Assembly: GCA_000688735.1
Location: Scaffold8:1542036-1547800[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 5.2 3.9e+02 1.9 0.2 2 23 32 54 31 54 0.87

2 20 0.027 2.1 9.1 5.7 2 23 164 189 163 189 0.90

3 20 3.5e-06 0.00026 21.4 0.2 1 23 271 294 271 294 0.97

4 20 2.4 1.8e+02 3.0 0.4 5 19 312 326 309 327 0.90

5 20 0.33 25 5.7 5.3 1 23 334 356 334 356 0.94

6 20 0.0002 0.015 15.9 2.6 1 23 362 386 362 386 0.95

7 20 0.0096 0.72 10.5 1.7 1 23 392 416 392 416 0.96

8 20 8.4e-05 0.0064 17.0 1.3 1 23 422 444 422 444 0.98

9 20 1.4e-06 0.00011 22.6 0.3 1 23 450 472 450 472 0.98

10 20 0.34 26 5.7 0.2 2 23 515 537 514 537 0.90

11 20 3.6e-05 0.0027 18.2 1.4 1 23 643 666 643 666 0.95

12 20 8e-05 0.0061 17.1 0.2 1 23 747 770 747 770 0.97

13 20 2.2 1.7e+02 3.1 0.7 2 19 785 802 784 807 0.92

14 20 0.079 6 7.7 7.5 1 23 810 832 810 832 0.97

15 20 5.9e-05 0.0044 17.5 0.8 1 23 838 862 838 862 0.96

16 20 0.00022 0.017 15.7 2.3 1 23 868 892 868 892 0.98

17 20 1.1e-05 0.00087 19.7 1.7 1 23 898 920 898 920 0.98

18 20 5.8e-06 0.00044 20.7 0.3 1 23 926 948 926 948 0.97

19 20 0.017 1.3 9.8 3.3 1 23 954 976 954 976 0.91

20 20 0.00012 0.0093 16.5 0.1 1 23 982 1004 982 1004 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	5.2	3.9e+02	1.9	0.2	2	23	32	54	31	54	0.87
2	20	0.027	2.1	9.1	5.7	2	23	164	189	163	189	0.90
3	20	3.5e-06	0.00026	21.4	0.2	1	23	271	294	271	294	0.97
4	20	2.4	1.8e+02	3.0	0.4	5	19	312	326	309	327	0.90
5	20	0.33	25	5.7	5.3	1	23	334	356	334	356	0.94
6	20	0.0002	0.015	15.9	2.6	1	23	362	386	362	386	0.95
7	20	0.0096	0.72	10.5	1.7	1	23	392	416	392	416	0.96
8	20	8.4e-05	0.0064	17.0	1.3	1	23	422	444	422	444	0.98
9	20	1.4e-06	0.00011	22.6	0.3	1	23	450	472	450	472	0.98
10	20	0.34	26	5.7	0.2	2	23	515	537	514	537	0.90
11	20	3.6e-05	0.0027	18.2	1.4	1	23	643	666	643	666	0.95
12	20	8e-05	0.0061	17.1	0.2	1	23	747	770	747	770	0.97
13	20	2.2	1.7e+02	3.1	0.7	2	19	785	802	784	807	0.92
14	20	0.079	6	7.7	7.5	1	23	810	832	810	832	0.97
15	20	5.9e-05	0.0044	17.5	0.8	1	23	838	862	838	862	0.96
16	20	0.00022	0.017	15.7	2.3	1	23	868	892	868	892	0.98
17	20	1.1e-05	0.00087	19.7	1.7	1	23	898	920	898	920	0.98
18	20	5.8e-06	0.00044	20.7	0.3	1	23	926	948	926	948	0.97
19	20	0.017	1.3	9.8	3.3	1	23	954	976	954	976	0.91
20	20	0.00012	0.0093	16.5	0.1	1	23	982	1004	982	1004	0.99

Sequence Information

Coding Sequence: ATGTTAAAAACTTTACCGATAATTAAATTCAATGATGTTTCTAAAGAGAAATGTGGCGAGATTTTTTGCCACCGTCCTAAGGAATTTACAATATATTGTACACTTTGCGAGATGAAGTCCTTTGATTTTACTGATTTTTTAATTCATATTGAAAATGTGCACTTCAATACCGATTTATTGAAATTGGAAAATCCAGGTATGGGTTATGCGGATTTGTTTGAAATGAATGTTAAAAAGGAGAACGTCTTTGCCGAATACGAAACTCCAATGGAAGAGATATGCTGCGACAATAGGTCAGATATTTTAAATGCCAGCAGTCATGTTGAAAGTGGAAATGAAGATAGTGAAGAAGTGTTAACTGTATTAAAGAGAACTAAAGGGAGATCAAGAGTAACAAGTAGTAAAAGGAAACATAATAAAGCTAAAGTGAATTGCAATCATCCAGATGCCGATAAAAATAGTAAGTCACCGAATATGACCAAGGGCTTAAAGTGTCATCAATGCATTCATTGTAGTAAAACTTTCATTAACCATGGCCTGCTAAAAATACACGTCGCTAGAGTTCACAAAAGTTTAGCTAAAGAGAAGGAGAGCAATGCCGGCATAAACTTGATAAATAATGAAACACCTGTGGATGAGCAAGTCTTTGGACACCAGAAACTGTTAGACGAGTTAGTGATTGCTGAAAATACGAATGAAAAGTATAGCAAAGATGTTGAAAATATTAATTCAGAGGAGCGTGATGATAACCAGGCTTCAGATGGTGATTATGAACCCGATTTAGACAACACTGTCGATAACAAGAAGAGCTTTCAATGCGAAGATTGCGACAAAACTTTAAGTAGTTCCGCTTCTCTAAGAGCACACATTGCTAGATATCACGAGACAAGGAGTAAGAAACCAAAGGAATCAAACAATGGAATGCCATGCATTGAATGCGAGGAGATGTTTACAAATCAAAAACTTTACGATCGTCATTGCGTTGAGGTACACGACGGTTTCAAATGTTCCTTGTGTGAGAAAAGGTTCAAAATACGTTATAGCTGTAAACGTCATGAACTGCTGCATAATAAGATAAAAGAATTCATTTGCTCCTTTGAAGGTTGCAATAAAAGTTTCACGGAACATTATTACCTAAAGCGTCATCAAGACGTACATCAAACTGAACGTAACTTTATATGTAATTTTGAAAATTGTGGTAAGGCATTCCATGCGAAACGTCGTTTATGGCAACATCAGAAAATACATACTAAACCGAAAAATTTTATTTGCGATATGTGCGGCTATAGTTGCCGCGAAAGAGTCACATTACGCGTCCATCAACGCATACATACGGGTGAGAGACCATACGTTTGTAAGATCTGCAATAAAACATTCATATCCAGCTCGTCGCTAGGAGATCATATGGCGTCACATGCGAGTACTCGAACACATGTATTCAGTAAAGCTATGTTGAAGACTTTACCAACAATAAAATTTAACGAAGCTCCTAAAGCGAAATGTGGTGAGATTTTCTGCCACAGTTCCAGGGACTTTACAATATATTGCACACTCTGCGACATGAAATCTTTTGATTTTTCCGATTTTATAATGCATATTGAGAATGTCCACTTCGATGGTGATTTGTTAAAGTTGGAAGCTTCAAAAATAGATTATGCGCAATTTTTGGAATTGAATGTGAAAGATGAAAACAGCTGTGCCGAACAAGAAGTTTCAGTTGATGAAATGTCCTGGGAGGATATGCCAGACATTTTGAATAGGAGCAGCAGTACAGAAAGTAGTAAAGAAGATGTTGAAGAAGTCTTGACGGTTCTTAAGAGAAATAGGGGaaaaacaaaagaaagcaacaataaaaaaGCACGCCATAGTCAGGGTAGCTTGGGCAGAGGTAGTAAGGAAACAAATGCAACAGAGATGTTGAAATGCCATCAATGCGAGCATTGTAATAAGATTTTCGTTAATCCTGGCCTATTGAAAATACACAAAGCGAGGATTCATAAAACGTTTGTAAATGaaaaaaaGAACGACAGGGAGTTAGATGACATACTCGTTGAAGACCGTGCTGATAGCAGAATGGATGAAAATCTGGAAACGTTAGAAGAATTAACGGTCACAAAAGACACATTTAAAAAGTACAATAAATATGCAAACATCGTTATATCAGAAGGTGATGAAAGTCAGGATTCAGATGAGAACTATGAACCTGAGTCAGAAAATAAGACCAACAATAAGAAGAGTTATCAATGCGAAAACTGCGGGAGAAGCTTAAGTAGCGTTGGGTCTCTAAAATCGCATATTGCTAGATTTCATAAAACAAGCAATAAAAAGCCAAAAGAATTGGATATCGAAACTCCATGTGCCGAATGTAATGAACTATTCGAAAATCAAAAGTTATACGATCGCCATTGCATTGACGTGCACGACGGCTTCAAATGTTCCATGTGTGACAAAAGATTCAAATTACGCCATCAGTGTAAACGCCACGAATTAATACATAAGGAAGCCAAACAGTTTGTTTGCTCCTTTGAAGGTTGCAATAAAGGTTTTACGGAGCAGTATTACCTGAAAAGACATCAAGATATACATCAAACTGAACGTAACTTCAAATGTGATTTTGAGAATTGCGGCAAAGCATTTCATACGAAGCGTCGCTTATGGGCCCATCAGAAAATACACACTAAGCCGAAAAATTTTATTTGCGATATTTGTGGATACAGTTGTCGCGAAAGGGAAACGTTGCGCGTCCATCAGCGCACCCATACAGGAGAAAGACCGTATGCTTGCAAAATCTGTAATAAACGTTTTATATCGAGCTCCTCGTTAGGTGAACATATGGCCTCTCATGCTAGTAGTCGAACGCATGTTTGTAAAGTTTGCAATGCGCGCTTTGCCCGCCAAAAGGCTCTATACCATCATAGTTTTTTACATTTGGACACAAAGAAATTCAAATGTAGAATATGCGGTAGTGCATATAAACAAGCAGCAGGATTGGCCGGTCATATGCGAAAACATCGGGAAGAAGACATGATAAAGGTGATGCCACTCGAATCAGAAATACCTTTATCGTCCGGTAATAATAACCTATTTGATGGATTTCTTAGTTAA
Protein Sequence: MLKTLPIIKFNDVSKEKCGEIFCHRPKEFTIYCTLCEMKSFDFTDFLIHIENVHFNTDLLKLENPGMGYADLFEMNVKKENVFAEYETPMEEICCDNRSDILNASSHVESGNEDSEEVLTVLKRTKGRSRVTSSKRKHNKAKVNCNHPDADKNSKSPNMTKGLKCHQCIHCSKTFINHGLLKIHVARVHKSLAKEKESNAGINLINNETPVDEQVFGHQKLLDELVIAENTNEKYSKDVENINSEERDDNQASDGDYEPDLDNTVDNKKSFQCEDCDKTLSSSASLRAHIARYHETRSKKPKESNNGMPCIECEEMFTNQKLYDRHCVEVHDGFKCSLCEKRFKIRYSCKRHELLHNKIKEFICSFEGCNKSFTEHYYLKRHQDVHQTERNFICNFENCGKAFHAKRRLWQHQKIHTKPKNFICDMCGYSCRERVTLRVHQRIHTGERPYVCKICNKTFISSSSLGDHMASHASTRTHVFSKAMLKTLPTIKFNEAPKAKCGEIFCHSSRDFTIYCTLCDMKSFDFSDFIMHIENVHFDGDLLKLEASKIDYAQFLELNVKDENSCAEQEVSVDEMSWEDMPDILNRSSSTESSKEDVEEVLTVLKRNRGKTKESNNKKARHSQGSLGRGSKETNATEMLKCHQCEHCNKIFVNPGLLKIHKARIHKTFVNEKKNDRELDDILVEDRADSRMDENLETLEELTVTKDTFKKYNKYANIVISEGDESQDSDENYEPESENKTNNKKSYQCENCGRSLSSVGSLKSHIARFHKTSNKKPKELDIETPCAECNELFENQKLYDRHCIDVHDGFKCSMCDKRFKLRHQCKRHELIHKEAKQFVCSFEGCNKGFTEQYYLKRHQDIHQTERNFKCDFENCGKAFHTKRRLWAHQKIHTKPKNFICDICGYSCRERETLRVHQRTHTGERPYACKICNKRFISSSSLGEHMASHASSRTHVCKVCNARFARQKALYHHSFLHLDTKKFKCRICGSAYKQAAGLAGHMRKHREEDMIKVMPLESEIPLSSGNNNLFDGFLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00749132;
90% Identity: iTF_00749132;
80% Identity: -