Gale019470.1
Basic Information
- Insect
- Glaucopsyche alexis
- Gene Symbol
- L
- Assembly
- GCA_905404095.1
- Location
- FR990051.1:14837474-14841737[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.61 67 5.4 5.8 1 23 3 25 3 25 0.97 2 17 8.2e-06 0.0009 20.7 4.1 1 23 31 53 31 53 0.99 3 17 2.5e-05 0.0028 19.2 0.1 1 23 59 81 59 81 0.98 4 17 2.7e-05 0.003 19.0 0.2 2 23 97 119 96 119 0.95 5 17 5.8 6.4e+02 2.3 0.1 9 23 150 165 146 165 0.93 6 17 0.29 32 6.4 0.0 3 23 220 240 219 240 0.97 7 17 2.3 2.5e+02 3.6 0.0 3 23 255 275 254 275 0.87 8 17 0.00012 0.013 17.1 1.1 1 23 283 306 283 306 0.94 9 17 0.01 1.1 10.9 0.2 1 23 311 334 311 334 0.93 10 17 0.0001 0.011 17.2 0.2 1 23 394 418 394 419 0.96 11 17 0.00019 0.021 16.4 0.1 2 23 475 496 474 496 0.96 12 17 1.4 1.5e+02 4.2 0.0 1 23 504 526 504 526 0.94 13 17 7.7 8.4e+02 1.9 0.4 2 23 534 555 533 556 0.89 14 17 8.8 9.6e+02 1.7 0.0 3 23 563 583 562 583 0.94 15 17 0.45 49 5.8 0.6 1 23 630 652 630 652 0.94 16 17 0.0052 0.57 11.9 0.1 1 20 660 679 660 682 0.95 17 17 0.098 11 7.9 0.3 1 23 689 711 689 711 0.94
Sequence Information
- Coding Sequence
- ATGCCATTTCGCTGCGAGTTCTGCTCCCGACTGTTCAAGCACAAACGGTCCCGGGACAGACACGTCAAGCTGCACACCGGGGACAGGAAATATCGTTGTGCGCATTGCGAGTCTGCCTTCTCGAGGAGTGATCATTTGAAGATCCATATGAAGACGCACGACAACCAGAAGCCGTTTCAGTGTACGGTATGCAACCGCGGGTACAACACGGCGGCCGCGCTGACATCACACATGCAAGGTCACAAGCGGGACCGGGAGGGGCGGGAGTCTGACAGGAGACGAGCCCTACGCTGCCTGAGATGCGGAGAAGGGTTCAGGAGATCTGATTTGCTGcagGCTCATATGTCCAGTGCTCACGGAGTGGAAACAACATCCATGACTCCCCCTCGTAGAGTCGCATCGCAGCCCCCACCCACTCTACTGGCCTGCATCTACTGCACCAGAGACACTTTCACGAGTATGGAGCAATTGCAATTACACGTGCGAGCAGCTCACTCTGCAATTTTGAATGGCGAAGCTCCTGCGCAATTTACAGTAGATCAGCCCGCTCCCACGGATCTAAGCAGACGAGGGACCGATGAACCGATCGCTAAGCGTCCACGATCAAGTGCAGGCTCTGTTACCTCAAAAACAACACTTTCTCCAAGTACTCTACTGTGTAATCAATGCGATGCTGCCTTACCAGATTTTGAGGCATTCCGAGCCCATTTAAAGGGACATCTCGAAGAAGGAGGCGAATTAAATCGCACGAGCCCAAACCCTTGTATTCATTGTGGAGCGACTTTTGCTGACGCAGCAGCTTCTGAGAGACACTTAGCCGCTCATTACCTAGCCGTGTCCTGTGAATACAATTGTCATAGCTGTGCCCGAAGTTTTCCTACGTCCGATGATCTTCAGAAACATTTACTAGAAATGCATACTCATCACATGTATCGGTGTTCACTATGCAAAGAAATGTTCGATTCGAAAGTTACTATACAGGCTCACTTTGCAATTGCACACAGCGGGGAAAATAAAGTGTGGGTATGTCGTTCGTGCGGCAGTGCCGGTGGGGCTCTACGAACGGAGGCAGAAGGCGCGGCCCATGTGCGGGCGAGACACGCAGCATCTAGGTGTGCTTGTGGGGCGGTGTTACCCGGGGCTAGAGCACTCAGAGCACACACCGCCGCGCACCACGCCTATCGATGCCCAGTACCGAACTGCACTGAATCGTTTGCCGTGCAGTATCTACTTGAAAGACACATACAGGCTCACCATGCTGTTGGGCAAACGGGTGTAAACGGTGACTTGTCCAGAGTAAAACGAGGTGAAAATAATAATGGACTGGAAGATGACAATTGTTCGCCCTGTGTTACCGGGCCTGAAAGCAATGGGCCCGTGTCCATTGATGACAGGCGACGCAAGAACGGCGCTGTGGCACTACAGTGCGCTTACTGCGGGGAGCGCACACGCAGTCGCGCAGAATTAGAGGCCCATACCCGCGCCCATTCCGGCACTGCTGCAACTCGCCACAAGTGCCTCATATGCGATGAAATACTTCCCTCGGCTGCGATACTCGCTGAGCATAAATTGACACATTGTAAGgtcATAGCTGGAGATGTATGCGCACGATGTCGTTCACGACTACCTTCAGAGGAGGCCTTTCTGAGCCACATGGCACGTCATCATCCTACTTTACCAGCGCCCTGCGTGATATGTCGCCAGACGTTAGCGTCGGAGGGTGAGGCACGATTGCATGCCAGATTCCACTTGCGTCCAAACGAGGACGAACAACGTTGTGCGATTTGTCTCCGAGCGCTAACTGATAGTGAAGCTGGTGACGGTGCAAGAGCTTGCTCGTCGTGTTACGCTCGACACGCAACCCCCAGACCACCGCCTCCAGCAGACCACGACTGTCGATTGTGCCGTAGAACCTTAGGCTCACCGACCCGATTACAAGCCCATCTCATTGAGCATACGTTCGCTGGCATTGGAGCGTTCACATGTTACTTGTGCTCAGCTATGTTCACTAGCGCCGCTGGTCTACAACGACATCTACCGGAGCACGCAGCGGCTCCGAGACCTTATGATTGTGGTCGATGCGGGCTAAAGTTTTTCTTCCGAGCCGAACTAGACAACCACGCCTTTGTACATTTGGAAGAGGCTGAAATTGCCCAAAGAGCGTTCTATGAGGCTTACGCCCGTGGTGCGGTTTCTGCATGGGCAGCTTTACAAACTCCAGAACCTACGCCACAACCACCAGTGACGTCACCTTCGCAAACAGTAGAGGTTCCGGTGAAACAGGAACCAGAAATAAAGGAGGAACGCCTAGATGAATACATAGAAGTTTCTTCGCCGCCTCCGCCTCAAGAAACACCGGCAAGCCCGAAGCCTGTCGTAAAACAGGAGAAGCCTGATGAAGAATGA
- Protein Sequence
- MPFRCEFCSRLFKHKRSRDRHVKLHTGDRKYRCAHCESAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQGHKRDREGRESDRRRALRCLRCGEGFRRSDLLQAHMSSAHGVETTSMTPPRRVASQPPPTLLACIYCTRDTFTSMEQLQLHVRAAHSAILNGEAPAQFTVDQPAPTDLSRRGTDEPIAKRPRSSAGSVTSKTTLSPSTLLCNQCDAALPDFEAFRAHLKGHLEEGGELNRTSPNPCIHCGATFADAAASERHLAAHYLAVSCEYNCHSCARSFPTSDDLQKHLLEMHTHHMYRCSLCKEMFDSKVTIQAHFAIAHSGENKVWVCRSCGSAGGALRTEAEGAAHVRARHAASRCACGAVLPGARALRAHTAAHHAYRCPVPNCTESFAVQYLLERHIQAHHAVGQTGVNGDLSRVKRGENNNGLEDDNCSPCVTGPESNGPVSIDDRRRKNGAVALQCAYCGERTRSRAELEAHTRAHSGTAATRHKCLICDEILPSAAILAEHKLTHCKVIAGDVCARCRSRLPSEEAFLSHMARHHPTLPAPCVICRQTLASEGEARLHARFHLRPNEDEQRCAICLRALTDSEAGDGARACSSCYARHATPRPPPPADHDCRLCRRTLGSPTRLQAHLIEHTFAGIGAFTCYLCSAMFTSAAGLQRHLPEHAAAPRPYDCGRCGLKFFFRAELDNHAFVHLEEAEIAQRAFYEAYARGAVSAWAALQTPEPTPQPPVTSPSQTVEVPVKQEPEIKEERLDEYIEVSSPPPPQETPASPKPVVKQEKPDEE*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01437318;
- 90% Identity
- iTF_01178881;
- 80% Identity
- -