Basic Information

Insect: Glaucopsyche alexis
Gene Symbol: RFX3
Assembly: GCA_905404095.1
Location: FR990052.1:22993618-23003951[+]

Transcription Factor Domain

TF Family: RFX
Domain: RFX domain
PFAM: PF02257
TF Group: Basic Domians group
Description: RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 3.4e-37 7e-33 114.2 0.0 3 78 91 166 89 167 0.97

2 9 0.012 2.4e+02 3.6 0.2 68 78 247 257 237 258 0.89

3 9 0.013 2.7e+02 3.4 0.1 69 78 286 295 283 296 0.86

4 9 0.01 2.1e+02 3.8 0.4 68 78 373 383 361 384 0.84

5 9 0.013 2.7e+02 3.4 0.1 69 78 412 421 409 422 0.86

6 9 0.013 2.7e+02 3.4 0.1 69 78 450 459 447 460 0.86

7 9 0.013 2.7e+02 3.4 0.1 69 78 488 497 485 498 0.86

8 9 0.013 2.7e+02 3.4 0.1 69 78 526 535 523 536 0.86

9 9 2 4.1e+04 -3.6 0.0 24 32 874 882 862 888 0.69

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	3.4e-37	7e-33	114.2	0.0	3	78	91	166	89	167	0.97
2	9	0.012	2.4e+02	3.6	0.2	68	78	247	257	237	258	0.89
3	9	0.013	2.7e+02	3.4	0.1	69	78	286	295	283	296	0.86
4	9	0.01	2.1e+02	3.8	0.4	68	78	373	383	361	384	0.84
5	9	0.013	2.7e+02	3.4	0.1	69	78	412	421	409	422	0.86
6	9	0.013	2.7e+02	3.4	0.1	69	78	450	459	447	460	0.86
7	9	0.013	2.7e+02	3.4	0.1	69	78	488	497	485	498	0.86
8	9	0.013	2.7e+02	3.4	0.1	69	78	526	535	523	536	0.86
9	9	2	4.1e+04	-3.6	0.0	24	32	874	882	862	888	0.69

Sequence Information

Coding Sequence: ATGGAAGTGCCTCGATACCGCGCGTACTACCCCTGTGAGGGCGGTACAGGAGTGAACTACCATGTCCAGTATGTGGAGTCCCAAGACATATACACGCAGCCCGGCCCGCAGCCGCAAATGGAGACGCTGCGCACCGCGTACCCGGTGTACAGCGTCACGgaggcgggcggcgcgggcggggcgGGCGCGGAGGCGGGCGCGGGCGAGTGGTGCGAGTTCTACGCCGCGCCCGAGCGGCCCGcctcgcccgcgccgccgcgcaTGCCGCCCGCCACCGTGCAGTGGCTGCTCGACCACTACGAGACCGCCGAGGGCGTGTCGCTGCCGCGCTCCACCCTCTACGCGCATTACCTGCGCCACTGCGGCGCGCATCGGCTCGAGCCCGTCAACGCGGCGTCGTTCGGCAAGCTCATCCGCTCCGTGTTCGTGGGCCTGCGCACGCGCCGCCTCGGCACGCGCGGCAACTCCAAGTACCACTACTACGGCATCCGCGCCAAGCCCGCCGCGTCCGCCGACCCGCTGTACAAGCCCGACGACGTCGCCGCGCCCACCGACGACGCGCCGCCGGCCGTAGACGAGCTCAAGGTGAGTACGGGCGTCACACAAGTACCACTACTACGGCATCCGCGCCAAGCCCGCCGCGTCCGCCGACCCGCTGTACAAGCCCGACGACGTCGCCGCGCCCGCCGACGACGCGCCGCCGGCCGTAGACGAGCTCAAGGTGAGTACGTATGGCGACACAAGTACCACTACTACGGCATCCGCGCCAAGCCCGCCGCGTCCGCCGACCCGCTGTACAAGCCCGACGACGTCGCCGCGCCCGCCGACGACGCGCCGCCGGCCGTAGACGAGCTCAAGTACCACTACTACGGCATCCGCGCCAAGCCCGCCGCGTCCGCCGACCCGCTGTTCAAGCCCGACGACGTCGCCGCGCCCGCCGACGACGCGCCGCCGGCCGTAGACGAGCTCAAGGTGGCGACACAAGTACCACTACTACGGCATCCGCGCCAAGCCCGCCGCGTCCGCCGACCCGCTGTTCAAGCCCGACGACGTCGCCGCGCCCGCCGACGACGCGCCGCCGGCCGTAGACGAGCTCAAGGTGAGTACGGGTGGCGACACAAGTACCACTACTACGGCATCCGCGCCAAGCCCGCCGCGTCCGCCGACCCGCTGTTCAAGCCCGACGACGTCGCCGCGCCCGCCGACGACGCGCCGCCGGCCGTAGACGAGCTCAAGTACCACTACTACGGCATCCGCGCCAAGCCCGCCGCGTCCGCCGACCCGCTGTTCAAGCCCGACGACGTCGCCGCGCCCGCCGACGACGCGCCGCCGGCCGTAGACGAGCTCAAGTACCACTACTACGGCATCCGCGCCAAGCCCGCCGCGTCCGCCGACCCGCTGTTCAAGCCCGACGACGTCGCCGCGCCCGCCGACGACGCGCCGCCGGCCGTAGACGAGCTCAAGTACCACTACTACGGCATCCGCGCCAAGCCCGCCGCGTCCGCCGACCCGCTGTTCAAGCCCGACGACGTCGCCGCGCCCGCCGACGACGCGCCGCCGGCCGTAGACGAGCTCAAGTACCACTACTACGGCATCCGCGCCAAGCCCGCCGCGTCCGCCGACCCGCTGTTCAAGCCCGACGACGTCGCCGCGCCCGCCGACGACGCGCCGCCGGCCGTAGACGAGCTCAAGGAGGCGCGCGGCGGTTCGGTGGACACGGCGGCGGCGAACGCGCACAGCGAGTACCTGGGCACGGTGGTGCCGCCCGACCCGCCCGAGCTGGAGGTGGCCGACCTGCCCGACGACATCCCGCCCGACAGCCTGCAGCTGCTGCGGGACCAGCACCGGTCCCACGGCGCGGAGTTCCTGGCGGCGGTGGCGGCGCTGGACACGGGCGGCGTGGAGCGCGCGCGGCGCGGCTTCTGGCGGCGCGGGGTGCGGCGCGCGGTGCTGTGGCGgctggcggcgcggcgcgacgTGTGCGCGTGGCTGCGGCGCGCCGACCTGCGCCTGTACCAGCGCGCCGTCGACCTGCTGCTGCCCGACGTGCTGCGCCCCATCCCGCCCGCGCTCACGCAGTCGATCCGCAACTTCGCGAAAGGTCTGGAGGCGGCGCTGGCGGCGGGCGGGGCGGGCGCGCCGGCTCGGGccgcgcgggcggcggcggcggcggcgggcgcgctCGCGGCCGCACTGCGACGTTACACCTCGCTCAACCATCTCGCGCAGGCGGCGCGCGCGGTGCTCAACAACCAGCACCAGATCCAGCAGATGCTGTCGGACCTCAACCGCGTGGACTTCCGCGTGGTGCGCGAGCAGGCCACGTGGGCCTGCGCCGCCGGCAGCGCGGCCGCCGCGCACCGACTGGAGGCCGACTTCAAGTCGTCGTTCGCGGCGACGCTGGGCCGCGGGCTGGGGCTGGAGGCGTGGGCGGCGTGGCTGGAGGGTTGCGTGCGCGCCGCGCTGGCGCCGCACgagcccgcgccgcccgcgcgcTCCGAGCGGTACGTGCCGCGCGCGCGCCGCCTGCTGCTCGACTGGTCCTTCTACTCCTCGCTCGTCATTCGCGAACTCACGCTCAGGTCGGCGGCGTCGTTCGGCTCGTTCCACCTGATCCGGCTGCTGTACGACGAGTACGTGTCGTTCCTCATCGAGCGCCGCGTCGCCGCGCACGACCGCCGCGCGCCTATCGCCGTCATGCGTCGCGACGAGGACGACGAGGAAGGCGACGGGGACTCCCCCGGCGAGGGTGAGGACCCCGAGGGCGAGGGCGCCGGTGGCTCCGGCGGCGACGAGCCCGACGACGACTGGGACTGGGGCGACGAGGAGGATGATGAGCCGGACGCCAAGCGCGCGCGCCGGGACGACTAG
Protein Sequence: MEVPRYRAYYPCEGGTGVNYHVQYVESQDIYTQPGPQPQMETLRTAYPVYSVTEAGGAGGAGAEAGAGEWCEFYAAPERPASPAPPRMPPATVQWLLDHYETAEGVSLPRSTLYAHYLRHCGAHRLEPVNAASFGKLIRSVFVGLRTRRLGTRGNSKYHYYGIRAKPAASADPLYKPDDVAAPTDDAPPAVDELKVSTGVTQVPLLRHPRQARRVRRPAVQARRRRRARRRRAAGRRRAQGEYVWRHKYHYYGIRAKPAASADPLYKPDDVAAPADDAPPAVDELKYHYYGIRAKPAASADPLFKPDDVAAPADDAPPAVDELKVATQVPLLRHPRQARRVRRPAVQARRRRRARRRRAAGRRRAQGEYGWRHKYHYYGIRAKPAASADPLFKPDDVAAPADDAPPAVDELKYHYYGIRAKPAASADPLFKPDDVAAPADDAPPAVDELKYHYYGIRAKPAASADPLFKPDDVAAPADDAPPAVDELKYHYYGIRAKPAASADPLFKPDDVAAPADDAPPAVDELKYHYYGIRAKPAASADPLFKPDDVAAPADDAPPAVDELKEARGGSVDTAAANAHSEYLGTVVPPDPPELEVADLPDDIPPDSLQLLRDQHRSHGAEFLAAVAALDTGGVERARRGFWRRGVRRAVLWRLAARRDVCAWLRRADLRLYQRAVDLLLPDVLRPIPPALTQSIRNFAKGLEAALAAGGAGAPARAARAAAAAAGALAAALRRYTSLNHLAQAARAVLNNQHQIQQMLSDLNRVDFRVVREQATWACAAGSAAAAHRLEADFKSSFAATLGRGLGLEAWAAWLEGCVRAALAPHEPAPPARSERYVPRARRLLLDWSFYSSLVIRELTLRSAASFGSFHLIRLLYDEYVSFLIERRVAAHDRRAPIAVMRRDEDDEEGDGDSPGEGEDPEGEGAGGSGGDEPDDDWDWGDEEDDEPDAKRARRDD*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -