Basic Information

Insect: Gerris lacustris
Gene Symbol: Hr39
Assembly: GCA_951217055.1
Location: OX578276.1:60527569-60541803[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.29 8.3e+03 -2.5 7.0 57 172 143 285 99 301 0.68

2 3 2.4e-09 6.7e-05 24.1 0.0 1 46 399 444 399 471 0.77

3 3 1.5e-69 4.2e-65 222.4 0.0 165 408 431 667 420 667 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.29	8.3e+03	-2.5	7.0	57	172	143	285	99	301	0.68
2	3	2.4e-09	6.7e-05	24.1	0.0	1	46	399	444	399	471	0.77
3	3	1.5e-69	4.2e-65	222.4	0.0	165	408	431	667	420	667	0.93

Sequence Information

Coding Sequence: ATGTATGCAGACAAATGCTGGTTCGTTTGTGGTTTTTGTTGCTTGGAGCGGCAGCCGGCAGGCGGTGGAAAAACTAGGAGAAACGACTTCTCATGTGCCACTTTTACTGATAACATGTTAAGCTTGGTATACAATGTTGGAGGAGGAGGCTGCTCTGTAGTTGTCGGCGAGAAATCAATCGTTGATGAGGACTCATCGGCTGCTGATGCAGAAGTTACAAATTTCACCAATGATGCAGTTAATTTGCGGCACAAGAAGAACGATGATGAAATCATCGAAAGGCCAATGTCATGGGAGGGGGAGCTCTCAGACTCCCAGCTAGCCACAATTAAACCTGAACCTAATGAGACATGCATCGAAAATTCAGTTCAAATTCCTCATGGGACCAATGATCCATCTATAGCTCACAGCGAAGATGAAAAGCACCATACTGTTAAATATGCTTTGGATCCTGTTaatgaaAAGACTGCAGAGAGTCTAAGATCCAGCACCTTAAGCTCTCAGACTGAACTTCCCCTCTTGGTGGATAAGCTATTAAGTAATGGTGTGTACTGTCGAAGTGGTCCAGTGGCTACTGCAAGCCCAGATTCAGCTGTATATTCCTGCTACTCACCTGGAGCGAGTCCTGTCACATCGAGGCATTTCCTATCTTCCTCTTCAGGTATCTCGAGTCCTTTTACACCTTCTCTGTCTAGGAATAACAGCGATGCCTCACAGTATGGTGGTTCCAATCATTCTTCTTGTTATTCGCACAGtTATTCATCAGTGTCTGTATCACCTACACAATTTTCTCCAACTCATTCACCTATCCAGGGTAGGCATATCCAGAGGACTAACTTCCCTTCACCTGTACTTAGTGCAAGAACAAGTTCACATAGTGAATTCCCAAACCATGatgAGGCTATAATTGTAGATGATAAAGTCTCTGGAGATCCTTTAGCTCATGCCTCCCCTGCTATTAGTAGACAACAATTAATTAACAGTCCTTGTCCTATTTGTGGAGATAAAATATCTGGGTTCCACTATGGTATATTTTCCTGTGAGAGCTGTAAAGGTTTTTTCAAGAGGACAGTCCAGAATAGAAAGAACTATGTTTGCTTAAGAGGTTCATCTTGCCCTGTCAGTATAGCTACGAGGAAGAAATGTCCTGCTTGTAGGTTTGACAAGTGTCTTACCATGGGCATGAAGTTGGAAGctATAAGAGAGGACAGAACGAGAGGTGGTAGAAGTACATACCAGTGTTCCTACACAGTACCTCCAGGTCTAGCTGAGCCTAAAGATACAACCTCTCATCACCCTAATGTACCCACCTTACTTCagGAAATCATGGAAGTAGAGCACCTGTGGCAATACAAGGAGAGTGAAGGTGGCGTTTCTCAACAACCTCCTCCCCCTATACAGATCAACAACTCTGACCCAAGTGCCAACCTTTGTAACATTGCAGACCACCGTCTCTACAAGATAGTCAAGTGGTGTAAATCACTTCCCttgtttaaaaacatatctATAGACGATCAGATTTCATTGCTAATCAATGCGTGGTGTGAGCTGTTACTATTCTCATGCTGTTACCGGTCCATGTCGAGTCCAGGTGAGATCAGGGTGTCTCTAGGTAAAAGCATATCTCTTGGTGAGGCACGTGCCCTAGGCTTGGCTCCACCTATAGAAAGAATGCTTAACTTCACTGATCACCTGCGCCGGCTTCGTGTTGACAACTATGAGTACGTTGCCATGAAAGTCATCCTTCTTCTTACATCAGATACAAGTGAGCTGAGAGAGCCAGAGAAAGTGCGTGCATCTCAGGAAAAGGCACTCCAAGCACTTCAGCACTATACCCTGGCTCATTATCCTGACATTCCTTCAAAATTTGGAGAACTTCTTCTCAGGATACCTGAGCTTCAAAGAACTTGCCAAGTTGGAAAGGAAATGCTTTCAGCTAAGAGTAAAGAAGGAGAAGGACCCAGCTTCAACCTACTTATGGAGCTTTTAAGAGGAGACCACTGa
Protein Sequence: MYADKCWFVCGFCCLERQPAGGGKTRRNDFSCATFTDNMLSLVYNVGGGGCSVVVGEKSIVDEDSSAADAEVTNFTNDAVNLRHKKNDDEIIERPMSWEGELSDSQLATIKPEPNETCIENSVQIPHGTNDPSIAHSEDEKHHTVKYALDPVNEKTAESLRSSTLSSQTELPLLVDKLLSNGVYCRSGPVATASPDSAVYSCYSPGASPVTSRHFLSSSSGISSPFTPSLSRNNSDASQYGGSNHSSCYSHSYSSVSVSPTQFSPTHSPIQGRHIQRTNFPSPVLSARTSSHSEFPNHDEAIIVDDKVSGDPLAHASPAISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGSSCPVSIATRKKCPACRFDKCLTMGMKLEAIREDRTRGGRSTYQCSYTVPPGLAEPKDTTSHHPNVPTLLQEIMEVEHLWQYKESEGGVSQQPPPPIQINNSDPSANLCNIADHRLYKIVKWCKSLPLFKNISIDDQISLLINAWCELLLFSCCYRSMSSPGEIRVSLGKSISLGEARALGLAPPIERMLNFTDHLRRLRVDNYEYVAMKVILLLTSDTSELREPEKVRASQEKALQALQHYTLAHYPDIPSKFGELLLRIPELQRTCQVGKEMLSAKSKEGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00743850;
90% Identity: iTF_00743850;
80% Identity: iTF_00743850;