Basic Information

Insect: Gerris lacustris
Gene Symbol: E2F7
Assembly: GCA_951217055.1
Location: OX578280.1:7979221-7993583[-]

Transcription Factor Domain

TF Family: E2F
Domain: E2F_TDP domain
PFAM: PF02319
TF Group: Helix-turn-helix
Description: This family contains the transcription factor E2F and its dimerisation partners TDP1 and TDP2, which stimulate E2F-dependent transcription. E2F binds to DNA as a homodimer or as a heterodimer in association with TDP1/2, the heterodimer having increased binding efficiency. The crystal structure of an E2F4-DP2-DNA complex shows that the DNA-binding domains of the E2F and DP proteins both have a fold related to the winged-helix DNA-binding motif. Recognition of the central c/gGCGCg/c sequence of the consensus DNA-binding site is symmetric, and amino acids that contact these bases are conserved among all known E2F and DP proteins.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 3.3e-17 4.8e-13 50.3 0.1 3 65 81 147 79 147 0.93

2 3 2.8e-11 3.9e-07 31.3 0.0 5 61 208 272 204 275 0.85

3 3 2.4 3.4e+04 -3.7 0.0 21 35 426 440 421 442 0.75

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	3.3e-17	4.8e-13	50.3	0.1	3	65	81	147	79	147	0.93
2	3	2.8e-11	3.9e-07	31.3	0.0	5	61	208	272	204	275	0.85
3	3	2.4	3.4e+04	-3.7	0.0	21	35	426	440	421	442	0.75

Sequence Information

Coding Sequence: ATGGGTTTTTACGAGTATTTCGGTGAAAGAATGGAGTCTTCGTCTTTTCATGTTTTGGGAACTCCTAAGAGAGTGGTTTTGAGCCCTGTAGACAACCGTAATAATGGCTCGCCTATTTCACCCATGGCAAATTTGAAGCTTTTGACAAAGGTCGCTACAAGTTACATGGATGAAAACTCGATTGACGTATCTTATCCttataagataaagaaaacaccTGTAAAAAATCAGCGCCAACTTAGATCTCTtggttatatttgtaaaaaATTTTTAGCATTGTATAATTTGAATATTCCTACGGGCCATTCAAAACAGATCTCTTTAGGAAACCTAACTTTACTTTTGGATATAGAAAAGAGGAGAGTGTATGATATCATAAACATAATTGCTAGTCTTCGCTATGCTTCTAAAGTCTGTAAAGATAAATATTCTTGGTTCGGTGACCAATATCTTGTGGCAACATTATGCGAGTTAAGAAATCTTGCATTCAGCAGAAATTATCATCTACATcttCAGAAGTGCTTTAATAACAATACACTGTTAGACATTTATGACCACAACCAAAATGCTGCAGACAACTTCTTTGATAATGATGAAAGGCAGATATTTGATGATAATAGAATCGGAGCTCTGTGCCAAAAGAGCATGATGTTGTTCCTAATTGCACCTAAGggtgaACCACTGAACTTCAGAATTATTTCTCAGATAATTCTTCCTCGAGATGTTCAAGATAAGACTGGTATGAGACGTTTGTATGATATTTCGAACGTGCTTGAATCGTTGGGACTGATACGCCGCTGTGATAGCAAGCACATGAAGAGACCGACATTTGTTTACTCTGGTCCTGAACTTCCCACTGAAACCTCTGaTAGTTTACCTGTTCCTGAAACTAAGCTAACTGATATAGAACACTTATCTGACACAAGTTTGGACGGTAGTGATTCAAAAATTTCATCCAACATCTTGGACGTAGTATCTAATGAGTTTCAACAAGAATTGGAGAAAATGAATTCGAAATTCATCGAGCCTCAACTTAGCGCTATATCCGCCAAGAAACAGCTGTTTCCTGATAATACTAAATCGGAAAACGGTTTTATAAAAGCTCCTCAATCCTCGTTTAAATTCACTTCCGCCGGTTTGGTTAAAGTGAACACGGATGAGAACATCCATCAATATTTGAAGATGGAGACTCATGCCGTCTTAACTCCGGCGTTTTCTCGTCTTTCCGATGTTAACAGTAACATACATCCTAAATTTAATGTGTCGCAGAGAGACGGTAGCatcattagaataaataaaatagccaGGCCTTTAAATGTGTATAAAATTGCGTCTGCTCAGAATTCATCCATTCAAAACGGCGGTATTTATAGAGTAGTTAAAAAGgggaatattataaatttagtgCAAATTAAATCTGCTCAATAG
Protein Sequence: MGFYEYFGERMESSSFHVLGTPKRVVLSPVDNRNNGSPISPMANLKLLTKVATSYMDENSIDVSYPYKIKKTPVKNQRQLRSLGYICKKFLALYNLNIPTGHSKQISLGNLTLLLDIEKRRVYDIINIIASLRYASKVCKDKYSWFGDQYLVATLCELRNLAFSRNYHLHLQKCFNNNTLLDIYDHNQNAADNFFDNDERQIFDDNRIGALCQKSMMLFLIAPKGEPLNFRIISQIILPRDVQDKTGMRRLYDISNVLESLGLIRRCDSKHMKRPTFVYSGPELPTETSDSLPVPETKLTDIEHLSDTSLDGSDSKISSNILDVVSNEFQQELEKMNSKFIEPQLSAISAKKQLFPDNTKSENGFIKAPQSSFKFTSAGLVKVNTDENIHQYLKMETHAVLTPAFSRLSDVNSNIHPKFNVSQRDGSIIRINKIARPLNVYKIASAQNSSIQNGGIYRVVKKGNIINLVQIKSAQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00742574;
90% Identity: iTF_00742574;
80% Identity: -