Basic Information

Insect: Gastrophysa polygoni
Gene Symbol: topi
Assembly: GCA_963576655.1
Location: OY755091.1:7183439-7191079[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0036 0.33 12.0 2.0 2 21 98 117 97 118 0.94

2 14 3.6e-06 0.00033 21.5 1.3 1 23 146 168 146 168 0.96

3 14 0.0088 0.81 10.8 3.5 3 23 176 196 175 196 0.95

4 14 1.8 1.7e+02 3.5 0.1 2 13 215 226 214 230 0.89

5 14 0.00028 0.026 15.5 0.8 2 23 291 312 290 312 0.97

6 14 0.39 36 5.6 0.0 1 21 318 338 318 339 0.90

7 14 0.024 2.2 9.5 3.4 3 22 356 375 355 378 0.90

8 14 0.0013 0.12 13.4 0.2 1 23 500 523 500 523 0.97

9 14 0.0012 0.11 13.5 0.1 1 23 527 549 527 549 0.97

10 14 7.7e-07 7e-05 23.6 2.4 1 23 555 577 555 577 0.98

11 14 0.022 2 9.6 0.2 1 23 583 608 583 608 0.96

12 14 0.075 6.9 7.9 2.9 1 23 614 636 614 636 0.86

13 14 4.8e-06 0.00044 21.1 0.3 1 23 642 664 642 664 0.98

14 14 1.6e-06 0.00015 22.6 1.9 1 23 670 693 670 693 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0036	0.33	12.0	2.0	2	21	98	117	97	118	0.94
2	14	3.6e-06	0.00033	21.5	1.3	1	23	146	168	146	168	0.96
3	14	0.0088	0.81	10.8	3.5	3	23	176	196	175	196	0.95
4	14	1.8	1.7e+02	3.5	0.1	2	13	215	226	214	230	0.89
5	14	0.00028	0.026	15.5	0.8	2	23	291	312	290	312	0.97
6	14	0.39	36	5.6	0.0	1	21	318	338	318	339	0.90
7	14	0.024	2.2	9.5	3.4	3	22	356	375	355	378	0.90
8	14	0.0013	0.12	13.4	0.2	1	23	500	523	500	523	0.97
9	14	0.0012	0.11	13.5	0.1	1	23	527	549	527	549	0.97
10	14	7.7e-07	7e-05	23.6	2.4	1	23	555	577	555	577	0.98
11	14	0.022	2	9.6	0.2	1	23	583	608	583	608	0.96
12	14	0.075	6.9	7.9	2.9	1	23	614	636	614	636	0.86
13	14	4.8e-06	0.00044	21.1	0.3	1	23	642	664	642	664	0.98
14	14	1.6e-06	0.00015	22.6	1.9	1	23	670	693	670	693	0.98

Sequence Information

Coding Sequence: ATGAACAGCAGCCTTGATAAACTTGATATAAACGTTCATAAAATATCAGACAATGAAGCAGTGGTCTGGTCATTACAATTCATATTGGATCCACACACAAGAGAACCGATTTCTAGGACATACCTCAACTCAGctgaaatcatttttaattGTTCTGGCGAAAACAAATTGAACCTCGCTTATGAAAGATTGAGAAAATACGAGGATGAGGTCAATTGTGTTGAAgtcgaagaattcgaaaattctGGGATGATAGTAGGTAAACCTGTATTGAATATTCCAACAATGATAAGGTGCCAAAATTGTGAGACTAATTTTCCAACAAGATACCAATATCAACGACATCAATGTGAATTCAACGCTGAAAAAGTGATTTTAAAACCTGAAACCGACCCTAACAGTATTGAACCGAATGATACGAATAAAGGCGAGAAACACATTTGCGAACTTTGTGATAAGCAATTcgtaaacaaaaataatttagaaCGTCATCAGGCTagtcatgaaattattcaaaagaaTATCTGCGAGCATTGCGATAAACATTTCGTTACTGAAAACAGATTGAGAATACATAAAGAAAATCACTGCAAGAAAGCAGGTGATGTTTCCAAATTCTATAGAAGCGATGTAGCTGTATGGAAGTGTATGAGATGCCACGAAGTTTTTTCTTCTCCATTGTCCGCGAAGTTCCATGTCTCAGTGTGTatggaattcattgaatatgaatctGCTGAACCACTGGAATGTAAGCAGACAATTATTTCGCAAAGTGGAGAAAAATGTTCTATCAACGCTGGGAATGGAAGCgaaaatatatatcaagatGAAGATAAAACCGTTGAAAAAGTGCAAACGGAACTGTTGTTACAATGTGAATTTTGCAATAGAACCTATGCCGAAAAGAATCTACTTCTGATACATCAACGAAAACATACAacagcaaaaaattatgaatgcgTGAATTGTTCTCAAGTGTTCGATTCTTACATCAATGCTGCACAGCATTGGATGAAAAAATGCACCGAATACGTGAGCCTATTTTATTTgccaaaattcattttatgtgaGAACTGCAACAGAACTTTCAAGTCCCATGAATTACTTTATACTcacaaaataaaaaagaagCATTATACTTCGAAATACCATGAATCGAATTCATGTGATTCAGAGAAGGACGTTATCGAAAGtagcattgaaaaaaaatccatggaTAATAAGGAAATTTTAAACAAACTCATAGAAGACGTCCTAAAAACACTCGATGTTCCGGTTACCAAACTATCGAACACTTATATAtccaatattcaaatgaataataacaatcaGCCTATGATTGATATTGCGAAAATCAAGATGGAAAATGTAGACTGCGAACATAATCATAGCTTCGAGCTGACAGAAAAGAGGAAGCgaggaagaaaaaggaaatacCCTAAAGGAATGATCACAAAATGTAGTAAACTCAGCTGTGAGATTGAAGAAGGATTCAGATATCAGTGCGAACGATGTGTCGAAGTTTTCGAAAACATCATCAATCTTGAAAAACACCGTGAAAAGGAACATGCAGCCAATTTCACATGTGAGGACTGTGGTCAGGTTCTTCAGAGCTCCAAAGCATTGATGATCCACAGTCGTGCCCACAAATGTTTGAAGCCGTATGTGTGTGAAACATGCGGAAGAAGTTACTCTCAGACTTCTCATCTGTGGCAACATATGAGGTTCCATCAAGGAATAAAACCGTTCGCTTGTCCTCACGAGGGCTGTGAGGCGAGATACACCATCAGACCGGACTTGAAGGATCACATAAGGAAAGTTCATACTCGAGAGAGACCTTTCAAGTGCAATGTTTGCGACAAATGCTTCTTGACTGGCTCTGTATATTACCAGCACCGACTGATACACACTAACGACAGAAGATATGCTTGTGATCTTTGCCCGAAGAGGTTTTTTCGAGCTGACGCCCTCAACAACCACAGGAGAATCCACACAGACGAACGGCCATATCCTTGCCATGTCTGTGGACGGGAATTCAGGCAAAAAGGGGATCGGAATAAGCACATCAGAACTCAGCATCCTGATGCCATCCTGATGATGTGA
Protein Sequence: MNSSLDKLDINVHKISDNEAVVWSLQFILDPHTREPISRTYLNSAEIIFNCSGENKLNLAYERLRKYEDEVNCVEVEEFENSGMIVGKPVLNIPTMIRCQNCETNFPTRYQYQRHQCEFNAEKVILKPETDPNSIEPNDTNKGEKHICELCDKQFVNKNNLERHQASHEIIQKNICEHCDKHFVTENRLRIHKENHCKKAGDVSKFYRSDVAVWKCMRCHEVFSSPLSAKFHVSVCMEFIEYESAEPLECKQTIISQSGEKCSINAGNGSENIYQDEDKTVEKVQTELLLQCEFCNRTYAEKNLLLIHQRKHTTAKNYECVNCSQVFDSYINAAQHWMKKCTEYVSLFYLPKFILCENCNRTFKSHELLYTHKIKKKHYTSKYHESNSCDSEKDVIESSIEKKSMDNKEILNKLIEDVLKTLDVPVTKLSNTYISNIQMNNNNQPMIDIAKIKMENVDCEHNHSFELTEKRKRGRKRKYPKGMITKCSKLSCEIEEGFRYQCERCVEVFENIINLEKHREKEHAANFTCEDCGQVLQSSKALMIHSRAHKCLKPYVCETCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCNVCDKCFLTGSVYYQHRLIHTNDRRYACDLCPKRFFRADALNNHRRIHTDERPYPCHVCGREFRQKGDRNKHIRTQHPDAILMM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00330962;
90% Identity: -
80% Identity: -