Basic Information

Insect: Galleria mellonella
Gene Symbol: -
Assembly: GCA_958496185.1
Location: OY292310.1:2274070-2275893[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.085 5.6 8.1 1.2 1 23 25 47 25 47 0.95

2 16 0.0074 0.48 11.4 0.1 2 23 76 98 75 98 0.93

3 16 0.066 4.3 8.4 0.1 3 23 120 141 118 141 0.92

4 16 0.00026 0.017 16.0 2.6 2 23 147 169 146 169 0.95

5 16 0.00089 0.058 14.3 1.2 1 23 174 197 174 197 0.96

6 16 0.39 26 6.0 0.1 2 23 200 222 199 222 0.93

7 16 0.012 0.79 10.8 2.5 2 22 229 249 228 249 0.93

8 16 0.0024 0.16 13.0 0.6 1 23 310 333 310 333 0.93

9 16 0.19 13 7.0 0.3 2 23 361 383 360 383 0.93

10 16 0.0088 0.58 11.2 0.9 2 23 406 429 405 429 0.96

11 16 0.00042 0.028 15.3 0.6 3 20 436 453 434 457 0.90

12 16 0.0067 0.44 11.6 0.4 1 23 462 485 462 485 0.97

13 16 0.00067 0.044 14.7 0.1 2 23 491 513 491 513 0.94

14 16 3e-05 0.0019 19.0 4.9 1 23 517 540 517 540 0.98

15 16 0.00013 0.0088 16.9 0.6 2 23 547 568 546 568 0.96

16 16 0.0021 0.14 13.1 2.3 1 23 574 596 574 596 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.085	5.6	8.1	1.2	1	23	25	47	25	47	0.95
2	16	0.0074	0.48	11.4	0.1	2	23	76	98	75	98	0.93
3	16	0.066	4.3	8.4	0.1	3	23	120	141	118	141	0.92
4	16	0.00026	0.017	16.0	2.6	2	23	147	169	146	169	0.95
5	16	0.00089	0.058	14.3	1.2	1	23	174	197	174	197	0.96
6	16	0.39	26	6.0	0.1	2	23	200	222	199	222	0.93
7	16	0.012	0.79	10.8	2.5	2	22	229	249	228	249	0.93
8	16	0.0024	0.16	13.0	0.6	1	23	310	333	310	333	0.93
9	16	0.19	13	7.0	0.3	2	23	361	383	360	383	0.93
10	16	0.0088	0.58	11.2	0.9	2	23	406	429	405	429	0.96
11	16	0.00042	0.028	15.3	0.6	3	20	436	453	434	457	0.90
12	16	0.0067	0.44	11.6	0.4	1	23	462	485	462	485	0.97
13	16	0.00067	0.044	14.7	0.1	2	23	491	513	491	513	0.94
14	16	3e-05	0.0019	19.0	4.9	1	23	517	540	517	540	0.98
15	16	0.00013	0.0088	16.9	0.6	2	23	547	568	546	568	0.96
16	16	0.0021	0.14	13.1	2.3	1	23	574	596	574	596	0.97

Sequence Information

Coding Sequence: ATGCGCAGAAGGAAAAATCTACAAATTGTGTTTAACAACACAAGCATACTACCATTCAAATGGCGAGGAAAGTATCTCTGCTTCTACTGCAGCAAAGATATCGCCGAATACACAGAATTGAGGAAACACACGAAATCGCACGGGAGCTGTTCTACTAAAGATCATTCCCTAAAAGTTTTGAAAGGTGGTCAAAACATGGAAATAAAATTGGACGTCTCGGAAATTACTTGTGAGATCTGCAACGAATCTTTCCCTTCATTCGATGAGATTTTAAACCATTTGTACATTAAACATAAGTTAGAATACGACAAAGCCGTGGACATGGCTATAGAAGAGTACAGATTGGTGGACTTGGCTTGTTTGGCGTGCGGTGAGAAATTTTCGTACTTCGGTTACTTAGTATCACACGTGAATAATAATCACCCCAAAAACTGTCTAATTTGTGACAAATGTAATCAGAAGTTTAACAAAAAGAGAGATCTGTTCTCCCACATGAAGAATTACCATCGAGAAGGTGGTTATCAGTGTGAAATGTGCCCACAAACATTCAGCTCTTTAAATATCTTGCGCAAACATAGAAATAACAGGCATTTGACTAGATGTAATATATGTCAATTGAAGTTACCGTCAGCTGCTTTAAAACAAAAGCATATAGAGTTAGAACATCCAGATGACGGGTCTCTGCAGTGTGATAATTGTTACAAGGAATTCCACACAAAGCATGGTCTAAAAATGCACGCTAGAAAATGCAAAGGCGAGGCAGATTTGTTcgaatttacaattaaaaaagagGGCTACGATGTTATGGACCTTGATGATAACTACGAGGATAAAGTGAAACGACCTAGTGTCAAGCAAATCCGTGAAAACATTCTCATAGTCATAAACATGTCCACAGCaataccatttaatttttacaagaaCAAATTTAATTGTTTCTACTGCTCCAAAGATTTCCCTGACTCTGATTCCATGAGAGAGCACACAGTTATGGAACACCCGGTATGCGATATGAAACAGAAATGCATCAGGAagtgcagggagtcagtggctTGCGTGAAAATCGATGTATCTTCACTCACTTGTAAAATTTGCTTCGAATCCATGAGTGATTTGGAAAAGTTACTGGACCATTTAATGTTGAAACATGAGGCTAACTATGATAAGTCTATTACGACCTGTCTGCAACCGTTTAGATTGATCAAAGACCATATGGAATGCCCGCATTGTCCCGGGGAAGTGTTTCGATTCTTTGGGACTTTACTAAAACACatgaataaaaaacatacaaacaacaatattatttgtgtatacTGCGGCCAGACTTTCAGACGCGATCAGAATCTGCGTGTTCACATTTGGAGACACCACAGAGATGGGCGCTTCAAATGTAACATTTGCGGTGCTGAGTGTAATATTCCTTCAAGACTGTACATGCATATGGCGAAAGCGCACGGAGTGAAAGCGGCCAAATGTCCAAAATGCCCTGAAGCGTTTGCAACGCAATATCTGAGACAGAAACATTTGATCGAAGCCCACGATTCAGGACACAAATGTACATATTGCGGTAAACTCTTCACACGAAACTCTTTCATGCGAGATCACATAAGACGGACACATTTGAAGGAGAAAAATGTGGAATGTTCCATTTGTAATATGAAATTCTTCAACAATATACTGTTGAGGCGGCATATGGTGAAACACAGCGGTGAAAAGAATTTTCACTGTGACATTTGCGGGGAAAGATTCTTCTGGAGAAAGAGTCTACGAACGCACATGGCTAGACATAATAAGAATTTGCATTCAATACAATTATTAAGTTAG
Protein Sequence: MRRRKNLQIVFNNTSILPFKWRGKYLCFYCSKDIAEYTELRKHTKSHGSCSTKDHSLKVLKGGQNMEIKLDVSEITCEICNESFPSFDEILNHLYIKHKLEYDKAVDMAIEEYRLVDLACLACGEKFSYFGYLVSHVNNNHPKNCLICDKCNQKFNKKRDLFSHMKNYHREGGYQCEMCPQTFSSLNILRKHRNNRHLTRCNICQLKLPSAALKQKHIELEHPDDGSLQCDNCYKEFHTKHGLKMHARKCKGEADLFEFTIKKEGYDVMDLDDNYEDKVKRPSVKQIRENILIVINMSTAIPFNFYKNKFNCFYCSKDFPDSDSMREHTVMEHPVCDMKQKCIRKCRESVACVKIDVSSLTCKICFESMSDLEKLLDHLMLKHEANYDKSITTCLQPFRLIKDHMECPHCPGEVFRFFGTLLKHMNKKHTNNNIICVYCGQTFRRDQNLRVHIWRHHRDGRFKCNICGAECNIPSRLYMHMAKAHGVKAAKCPKCPEAFATQYLRQKHLIEAHDSGHKCTYCGKLFTRNSFMRDHIRRTHLKEKNVECSICNMKFFNNILLRRHMVKHSGEKNFHCDICGERFFWRKSLRTHMARHNKNLHSIQLLS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01198043;
90% Identity: iTF_00833335;
80% Identity: -