Gmel010553.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Galleria mellonella
Gene Symbol
-
Assembly
GCA_958496185.1
Location
OY292293.1:11057021-11074836[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 3.4e-05 0.0022 18.8 2.9 1 23 426 448 426 448 0.97
2 20 0.0035 0.23 12.5 0.6 1 20 454 473 454 476 0.94
3 20 2.4e-05 0.0016 19.2 5.6 1 23 495 517 495 517 0.98
4 20 9.6e-06 0.00063 20.5 4.9 1 23 523 545 523 545 0.99
5 20 4.1e-05 0.0027 18.5 5.3 1 23 551 573 551 573 0.97
6 20 9.6e-06 0.00063 20.5 7.4 1 23 579 601 579 601 0.97
7 20 5.9e-07 3.8e-05 24.3 3.0 1 23 607 629 607 629 0.98
8 20 0.00012 0.0077 17.1 6.7 1 23 635 657 635 657 0.97
9 20 0.00012 0.0076 17.1 6.5 1 23 663 685 663 685 0.97
10 20 5.6e-07 3.7e-05 24.4 1.9 1 23 691 713 691 713 0.98
11 20 5.8e-05 0.0038 18.1 7.9 1 23 719 741 719 741 0.98
12 20 5e-05 0.0032 18.3 6.6 1 23 747 769 747 769 0.98
13 20 1.6e-06 0.00011 22.9 5.2 1 23 775 797 775 797 0.98
14 20 3.2e-06 0.00021 22.0 6.3 1 23 803 825 803 825 0.97
15 20 2.7e-05 0.0018 19.1 7.3 1 23 831 853 831 853 0.97
16 20 3.5e-06 0.00023 21.9 6.0 1 23 859 881 859 881 0.98
17 20 6.6e-05 0.0043 17.9 7.8 1 23 887 909 887 909 0.97
18 20 7e-06 0.00046 20.9 3.2 1 23 915 937 915 937 0.96
19 20 0.00033 0.022 15.7 0.5 1 23 944 966 944 966 0.96
20 20 0.94 61 4.8 5.2 1 23 976 998 976 998 0.98

Sequence Information

Coding Sequence
ATGAATCCAGAACATCATAATATCAATACGGGTGGTGGCCAACCTCCTGGAAGTTCAGAGTCTCAGAGTCAAAGAGTGCAAAATGCACAGCAGCAACAAGCAAGTAATATGCCTGCAACAACCTCTGCGACGGACTTGAGAGTGAATTCGGCGGCCGTAAACGTTGCTTTGTCTAGCGTCGCCAAATATTGGgtgtttacaaatttatttccgAGCCCCATCCCACAAGTTTCTGTTTACGGACTACCAACTGGAACACGAATAGAAAATGGAAAACCAGTTCagGATTTGGGACAGGCACATGCCAGTATACTTAATGGAGACCCCAACATCATCTTGGGCCATCATGCAGGTCAACCACAAGTCACTGTTTCTGCTGGGGCCCAACAAATTCCTGTGTCCCAAATTATTGCTACACAATCAGGACAAGCACATgAAGCACTGGTGGCACATAATCAACAGCAAGAGCTAGCACAGCAAGCCTCAAGTGCTGGAGCACAGGTCACTGTTACTCCAGGCCAACCCACTCATCAGCAGGTACCCAATAATCGGGTCGAGTTTGTACAACACCATAACATTGATATGGTAAATCATGTGGGGCATCATTCACAGCAGCATTTGATGCAACAACAACTGATGGCTAGTACTCGGCCAGAGCATACGAATCAACAGATACAATTAACTGTCAGTGAAGATGGCATTGTAACAGTTGTGGAGCCAGGTGGAGGGAAGCTTGTGGATAAGGAGGAATTACACGAGGCAATCAAAATGCCCACAGACCACACACTCACAGTACATCAATTGCAGCAGATAGTTGGACAACAGgtattgGACAGCGTGGTTCGTATAGAGCAGGCAACCGGTGAACCGGCCAATATTTTGGTGACGCATAACCCTGACGGAACCACTTCCATAGAAGCCAGCGCGGCTGACCCGTTGGCAATAGTCAAAGATGAAAAAAGCGCTAGCAAAATGGAGACAGCTCAGTTTGCTATACCTGCAGATATAAAGGACATTAAGGGTATTGATTTGAAAAGTGTTGGTGCAATGGGTATGGAGGGTGCAGTGGTGAAGATTTCTGCAGGATCATCAGAGCATGATCTCCATGCTATGTACAAAGTAAATGTGGAAGATCTCTCCCAATTACTTGCTTACCATGAAGTGTTTGGCAAACTCAATGCTGAAGGACAACAGCAAACAAAGgtaataaatgAAGTGGAGGTAGAGCCAGGTACCAGTGGCACCCTGGCAGAATCCGAGTCCTCCCCGGGCCACCACTCCTGTGACATTTGCGGGAAGTCCTTCCAATTTCGCTACCAACTTATTGTTCACagGCGATATCATGGCGAAAGCAAACCATACACGTGTCAAGTATGCGGTTCGGCGTTTGCTAATCCCGTCGAACTGTCACGACACGGAAAATGTCATCTTGCTGGAGATCCAGCTGAGAGACATGCAAAGAGGTCAACTCAAGACAAACCGTATGCCTGCACCACTTGCCACAAAACATTTTCTCGGAAAGAGCATCTCGACAACCATGTCCGCAGCCATACTGGAGAGACTCCATATAGATGTGAATATTGCTCGAAAACATTCACGCGTAAGGAGCATATGGTAAACCATGTGCGAAAACATACGGGCGAGACGCCGCATCGCTGCGAGATATGCAAGAAGAGCTTCACTAGGAAGGAGCACTTCATGAACCACGTTATGTGGCACACTGGTGAAACGCCGCATCATTGTCAAATTTGCGACAAGAAGTTCACTAGGAACGAGCATTTAGTGAACCATATGAGATCGCATACAAACGATACTCCGTTCCGATGCGAACTGTGTGGCAAGTCTTTTACAAGAAAAGAACACTTCACCAATCACATTATGTGGCACACGGGTGAAACACCTCATAGATGCGACTTTTGCTCTAAAACATTTACTCGTAAAGAGCATCTGTTGAATCATGTCCGCCAACATACGGGCGAATCGCCACATCGCTGCAACTTCTGTTCCAAATCGTTCACGCGCCGTGAGCATCTCGTGAACCACGTCCGACAACACACTGGAGAGACACCCTTTCAGTGTGGATATTGTCCCAAAGCATTCACCAGGAAAGACCACCTAGTGAACCATGTCCGTCAGCACACGGGCGAATCACCACATAAGTGTTCTTTCTGCACTAAATCGTTCACGCGGAAGGAGCATTTGACGAATCACGTGCGCCAACATACCGGAGAGTCGCCCCATCGTTGTTCTTTCTGCGCTAAGTCGTTCACAAGGAAAGAACATCTTACAAACCATATCAGACAGCATACGGGCGAAACGCCACACAAGTGCACGTACTGCCCGCGCGCGTTCTCCCGCAAGGAACACCTCAACAACCACATTCGCCAGCACACCGGCGACATGCCGCACTCTTGCACCTACTGCAACAAGAGTTTCACGAGAAAAGAGCATCTCGTTAATCATATCAGACAACATACCGGAGAGACACCGTTCAAGTGTACATATTGCACGAAATCCTTTTCACGGAAGGAGCACCTAACGAACCATGTGCACCTCCATACTGGCGAAACACCGCACAAGTGCCCGTTCTGTACTAAGACATTCTCTCGGAAGGAGCATTTGACCAACCATGTCAGGATCCACACGGGCGAGTCTCCGCACCGGTGCGAATTTTGCCAGAAAACATTCACTCGTAAGGAGCATCTCACCAACCACTTGAAGCAGCATACTGGCGACACACCGCACGCCTGCAAAATCTGCGCCAAACCCTTTACCAGAAAAGAACACCTTGTTACTCATATGAGATCGCACAGTTGCGGCGAACGCCCATTCAGTTGTAACGAGTGCGGTAAATCATTCCCGTTGAAAGGCAACCTACTATTCCACGAACGGTCACATAACAAGGGCAATGGCGGTGCGAGGCCCTTCAGGTGCGATGTCTGTTCGAAGGACTTCCTGTGTAAAGGACACCTGGTATCTCACCGTCGCACGCACGCGGAAGCGGGAGGTGCCGCAGGCGGGGCAGCGGGCGGAGCACCCACTGCGGCGGAATGCGGCTGCGACACGGCGCCCGATGCTGAGTGCACTAAGTGCGACAAGGGAGACGTCGAGCGGCCGGAGAGAAAACACGACATTAGCCGGACAACAACAGAAAACAGACCTGCTGAAAGTAGTATCACACAAAACCCCCAGAATAGCACAACTGTGATGCAAATAACAAatcaaCAAGTTCGCGCGGGCGTCGCGACGAGCGGTTCCGATGTAGCGGGTGTGACAGGCGTGGCGAGCGTGTCGGGCGTGGCGAATGTGGCTGCTAGCGGTACGTTCGCGCATCCCGCCGCCGCCACACACCACGCCGGCGCCGCTATACACCACCCCGTCACTGTGAACTACTAG
Protein Sequence
MNPEHHNINTGGGQPPGSSESQSQRVQNAQQQQASNMPATTSATDLRVNSAAVNVALSSVAKYWVFTNLFPSPIPQVSVYGLPTGTRIENGKPVQDLGQAHASILNGDPNIILGHHAGQPQVTVSAGAQQIPVSQIIATQSGQAHEALVAHNQQQELAQQASSAGAQVTVTPGQPTHQQVPNNRVEFVQHHNIDMVNHVGHHSQQHLMQQQLMASTRPEHTNQQIQLTVSEDGIVTVVEPGGGKLVDKEELHEAIKMPTDHTLTVHQLQQIVGQQVLDSVVRIEQATGEPANILVTHNPDGTTSIEASAADPLAIVKDEKSASKMETAQFAIPADIKDIKGIDLKSVGAMGMEGAVVKISAGSSEHDLHAMYKVNVEDLSQLLAYHEVFGKLNAEGQQQTKVINEVEVEPGTSGTLAESESSPGHHSCDICGKSFQFRYQLIVHRRYHGESKPYTCQVCGSAFANPVELSRHGKCHLAGDPAERHAKRSTQDKPYACTTCHKTFSRKEHLDNHVRSHTGETPYRCEYCSKTFTRKEHMVNHVRKHTGETPHRCEICKKSFTRKEHFMNHVMWHTGETPHHCQICDKKFTRNEHLVNHMRSHTNDTPFRCELCGKSFTRKEHFTNHIMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSFCTKSFTRKEHLTNHVRQHTGESPHRCSFCAKSFTRKEHLTNHIRQHTGETPHKCTYCPRAFSRKEHLNNHIRQHTGDMPHSCTYCNKSFTRKEHLVNHIRQHTGETPFKCTYCTKSFSRKEHLTNHVHLHTGETPHKCPFCTKTFSRKEHLTNHVRIHTGESPHRCEFCQKTFTRKEHLTNHLKQHTGDTPHACKICAKPFTRKEHLVTHMRSHSCGERPFSCNECGKSFPLKGNLLFHERSHNKGNGGARPFRCDVCSKDFLCKGHLVSHRRTHAEAGGAAGGAAGGAPTAAECGCDTAPDAECTKCDKGDVERPERKHDISRTTTENRPAESSITQNPQNSTTVMQITNQQVRAGVATSGSDVAGVTGVASVSGVANVAASGTFAHPAAATHHAGAAIHHPVTVNY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01030446;
90% Identity
iTF_00008211;
80% Identity
-