Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.033 4.6e+02 2.2 0.0 21 44 138 161 132 165 0.88

2 7 0.00035 4.7 8.6 0.2 21 44 166 189 162 197 0.87

3 7 0.028 3.8e+02 2.5 0.1 21 44 194 217 190 221 0.84

4 7 0.0015 20 6.5 0.0 21 45 222 246 217 249 0.91

5 7 0.012 1.7e+02 3.6 0.1 22 45 251 274 246 281 0.83

6 7 0.0015 21 6.5 0.0 23 46 280 303 276 309 0.86

7 7 2.5e-05 0.34 12.2 0.1 21 45 306 330 302 336 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.033	4.6e+02	2.2	0.0	21	44	138	161	132	165	0.88
2	7	0.00035	4.7	8.6	0.2	21	44	166	189	162	197	0.87
3	7	0.028	3.8e+02	2.5	0.1	21	44	194	217	190	221	0.84
4	7	0.0015	20	6.5	0.0	21	45	222	246	217	249	0.91
5	7	0.012	1.7e+02	3.6	0.1	22	45	251	274	246	281	0.83
6	7	0.0015	21	6.5	0.0	23	46	280	303	276	309	0.86
7	7	2.5e-05	0.34	12.2	0.1	21	45	306	330	302	336	0.88

Coding Sequence: ATGTTTACGAAGCAAGTAGACTTTTCTTGGCACTTGTTAACCAGTCACCGTTTAAAAGGAAGGAAATTATATAAGACTAAAATCAAGCAGAAACAAATCAACAATACTAAAACTACAATTAGTTGTAAAACAATTCCTATTGATCGTAATATAGTTGTAaaagaagaaattgaaatagTCGAACACGAATTAAAAGAAGAATTACAGGAGACAGATCAATTGAATAACGTTGATGATTTTAAATCATGCTTTGAcgaaaatgttattaataaCCACATTAATGCTGACAACTGTGATACAGATGAAAAGacacatttaaatgaaaaagaaaagcCTGTTATGAAGTGTGATTTTTGTGCAAACACTTTTTTACACCAAAGTCAGTTAATTGTACATATGCGACTCCATACAGATGAAAAGCCATATAAATGCGAAGTTTGCTTGAAATCATTTAAATTCACATACAATTTGAATTTACATATGCGCTGCCACACAGGGGAAAAACCATATGAATGCAAAGTTTGTTTAAAATCCTTTAGAAGAAGTGACCAAGTGAGAAAACACATGCTTTGTCACACAGGAGAAAAACCGTATAAATGTGACATTTGTTTGAAATCATTCTCGCAGAAAATTCAGTTGACTGTACATATGCGTTACCATACAggtgaaaaaccattcaaatgcgAAATTTGTTCAAAGTCATTTGGAGAGAAAAGAGCTTTGAATAGACATATGCGTTGTCACACAGATGAAAAGTCAATCAAATGCGAAATATGCTCAGAGTCATTTGGAGAGAAAAGAGCATTGAATAGACATATGCTTTGTCACAAAGGATTAAAACCGTACAAATGCGAAATTTGCTTAAAGTCATTTGGAGAGAAAAGAACTTTGAAAAGACACATGCATTGCCACACAggtgaaaaaccattcaaatgcgAAATTTGCTTAAAGTCATTTGGAgagaaaagaaatttgaaaagaCATATGCGTTGTCACGCAAAGGAAAAAACCatataa
Protein Sequence: MFTKQVDFSWHLLTSHRLKGRKLYKTKIKQKQINNTKTTISCKTIPIDRNIVVKEEIEIVEHELKEELQETDQLNNVDDFKSCFDENVINNHINADNCDTDEKTHLNEKEKPVMKCDFCANTFLHQSQLIVHMRLHTDEKPYKCEVCLKSFKFTYNLNLHMRCHTGEKPYECKVCLKSFRRSDQVRKHMLCHTGEKPYKCDICLKSFSQKIQLTVHMRYHTGEKPFKCEICSKSFGEKRALNRHMRCHTDEKSIKCEICSESFGEKRALNRHMLCHKGLKPYKCEICLKSFGEKRTLKRHMHCHTGEKPFKCEICLKSFGEKRNLKRHMRCHAKEKTI

Sequence clustering based on sequence similarity using MMseqs2