Basic Information

Gene Symbol
-
Assembly
GCA_963978555.1
Location
OZ021711.1:11452451-11458952[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.04 6.2 8.6 1.2 2 23 148 169 147 169 0.96
2 16 0.055 8.4 8.2 4.9 3 23 177 197 175 197 0.96
3 16 0.0014 0.22 13.2 0.6 1 23 204 226 204 226 0.96
4 16 0.0004 0.062 14.9 0.9 1 23 333 355 333 355 0.99
5 16 0.00019 0.03 15.9 8.6 2 23 362 383 361 383 0.97
6 16 0.0013 0.2 13.4 5.7 2 23 407 429 406 429 0.94
7 16 3.1e-06 0.00048 21.6 2.3 2 23 500 521 499 521 0.96
8 16 0.00076 0.12 14.1 0.9 1 23 527 550 527 550 0.92
9 16 1.3e-06 0.00021 22.7 0.8 1 23 555 577 555 577 0.98
10 16 2.6e-06 0.00041 21.8 2.2 2 23 588 609 587 609 0.97
11 16 1.1e-07 1.7e-05 26.2 0.9 1 23 616 638 616 638 0.97
12 16 2.4e-05 0.0037 18.8 1.6 3 23 650 670 648 670 0.92
13 16 7.9e-05 0.012 17.1 4.4 1 23 676 698 676 698 0.99
14 16 3.3e-05 0.0052 18.3 1.7 1 23 704 726 704 726 0.96
15 16 5.1e-07 7.9e-05 24.0 0.4 1 23 732 754 732 754 0.99
16 16 0.00012 0.018 16.6 0.1 1 23 760 784 760 784 0.93

Sequence Information

Coding Sequence
ATGATTAATAAAGACTCCGATCTTATTATAGACAAAATATGTCGGTGTTGCATGTGTGAAAATGAAAACATGCTCAACATGTTTGAGCAGAATGATGAAGAGGAGGCGGAAGATTCTACGACACTTCTATCAGATATGCTAGTGGCTTGTGCTTCAATTGAGgTTTCCTCTGGGGATGGTTTGCCAAATAAGTTGTGTAAAAGTTGCGAAGAAAAGTTGAAAACTGCCTATGAGTTCAGGAAATTATGTCAAAAATCAGATACAACTTTAAAGGATCTCACTCAGGATACAAAAAAAGGAATTCGGCAAGAAGAAAATATTGTTGTACAACCAGATCTACATGATGATGTTTTTATTGAAGATGAAGATAATGTTCCCCTTTTAGAAAGAGGTATTAAACGAAAACGAGGTAGACCTAGAAAGAAAGATGTGGAGCATTTAACGTGTCAGTTTTGTAATAAAGTAATGCAGACTAAGAAAGGTCTAAGAATACATCTTAGTTCTCATGCAGGTGAAAAGTTACAACATTGCTTATTTTGTGAAGCTAAATATACTAGAACTAATCACTTGCTAAAGCACATTAATACTCATGATAAACCTGGTTTAATACATCCTTGTGAAAGTTGTGAAAAAACCTTCACTGTGGCAGCTGAGCTATATCAACATACTAAAGATCATGAGGAGCCTGAGAACAATATATCAGggaacataattaaaataaaaaaagaaattaaaacagAAGGACCTGAACTTTTCGATATAATCAGGGAAGAGAAAAGATTTGAGAACCAAATACTAACTGATCAAGATCAAGTTGTAAGTCATTATAGTGATCAAGATGATAATGGCTTCAATGATTTTGCAGCCAGTGATGGGGATGATAGTAAAGGTAGCGATGAAGACTTTACCATAGCACTTGATGAAAAAAAGACtaaaggaaggaagaagaagaaagtgAAGACTGAAGATGCAGGACAAGATAAAGATAAAGCATTGTATGAATGTAAGGAGTGTTCTAAAGTAATGACAACATATTTAGGACTTAAAATCCACATGAGGAAACATACTGGAGCTGATTTATCTACATGCaatCTATGCAACAAGTCTTTCACTAAACATAGTCATCTTGTAAGACATTTACACACTCATGGCATAGTTGACGAAGAGAAAATGAATGCTTTCAAGAAATATACAGACTCAAAAGGGAAAAAGATCATGGAATGTGAATATTGCGATCGAAAATTCAAATACAAGAAGAGTTTTTTACACCACATGCACCAGGAACATGGTATGGATGAGTTTGATAGTGATTTTGATAAACTAGAAGGCGAGAAATCCAAGAAATTAAAATCTGAATCGAGAGATGAATTTAACAAAATGGAAAACGATTTGAAACATGATGAGCTTCACATTGATAACAAGCAAGAAGATGATGATGGTGATATTGGCATAGATGCTGAAAATGTATTCATAAAGAAAGCAAGAAGTAAAAATCAAGTTTGTCATGTATGCGGTGCATCATTTTCAAGAGCAAACCATCTTACCAGACATATGACATTACATCGTGCTGTTCTTGTTCATCAGTGTGATAgATGTGAAAAGGCATTTGCTACAGATGAACATCTTAAAGTTCATGTTGAAGAGGAACATATCAACAAACCCTATGTATGCACAGTTTGTAACAAACCATTCAGCAGAGGCGAGCATTTAATAAGACACTTGAAAGTACATCAGAATACTACCGATAAAGATACTAATTTGAAATGTTCCATATGTGAAACTAGCTTCACAAGaTCTGATCATTTGGCACGGCACACGAAAATCCATTTACTTCAAGACAAGCGCCACGTATGCGGGGAATGTGGCAAAGCTTTTAACCGTTTAGACAACCTAAAGACTCACCAGAGGATCCACACCGGCGAAAAGGATACCTCAAAGTTGCATTTGTGCATCTATTGTGGAAAGGAATTCAATAATTCCAGCAACATGattGTCCACATGAGGCGTCATACAGGTGAAAGACCCTACAAATGCAGTGAATGCGGTAAAGGTTTTCCAAGATCCCATGATTTGAAATGCCATGAACGTACACATTCAGGTGAAAAGCCGTATCTTTGTACTTTATGTGGCAAATCATTTAATAAGAGCAATAAATTGTTGCGTCACAGTAGAGTTCACACCGGAGAGCGTCCTTATGTATGTAATATTTGTAGCCGAGCATTTACACAATCCAACGATCTAGCGTTACATATGCGTAGACATACTGGAGCCCGACCGTACGCTTGTGGTGTATGTCCGGCACGATTTATACAATCCGGACAATTGAAAACGCATAGAAGAACAACTGGTCATTGGATGGATGTACAACCGGATCTTAAAGGAGGACATCGGGTTGAACCAGTGACTCCTGCACATGAACCTATGCCTATTAGGTTTAAAGTTCACagGGCTATGAAGAAAGAACAAAATATTCTTGAACAAGCTGGTCTGATGACAACTCAACCTTCAACTTCTGAAGGCATTTCCATGAACAATCAAATCCCGACCATCCAAAGTGAACCTCATCGAATTGTAATGGGGATTATGGGCAATTTAAAGATCCCCGGACCAGATTCCAGCATCCAACCGCTGCTAATTGACAGCGCTAAGTTAGCAGAACTGCAAAACGCAGGATTAGTGAACCTACCATCAGTTATACAAACAACGAATGGCGATGAAATCAAATTGAAATCGGAAGTGGGAAACTTTGGTATGCCTCAAGAAATCGAAAAACGGGAAGGTAACACAAACAACTCGTATCAGGACGATGTAGTGATTTATTCGAGTGTAGGGCATACTTCGACTACTTATACAAGcagtgaaaatttcaattttcaaagttttCATTAG
Protein Sequence
MINKDSDLIIDKICRCCMCENENMLNMFEQNDEEEAEDSTTLLSDMLVACASIEVSSGDGLPNKLCKSCEEKLKTAYEFRKLCQKSDTTLKDLTQDTKKGIRQEENIVVQPDLHDDVFIEDEDNVPLLERGIKRKRGRPRKKDVEHLTCQFCNKVMQTKKGLRIHLSSHAGEKLQHCLFCEAKYTRTNHLLKHINTHDKPGLIHPCESCEKTFTVAAELYQHTKDHEEPENNISGNIIKIKKEIKTEGPELFDIIREEKRFENQILTDQDQVVSHYSDQDDNGFNDFAASDGDDSKGSDEDFTIALDEKKTKGRKKKKVKTEDAGQDKDKALYECKECSKVMTTYLGLKIHMRKHTGADLSTCNLCNKSFTKHSHLVRHLHTHGIVDEEKMNAFKKYTDSKGKKIMECEYCDRKFKYKKSFLHHMHQEHGMDEFDSDFDKLEGEKSKKLKSESRDEFNKMENDLKHDELHIDNKQEDDDGDIGIDAENVFIKKARSKNQVCHVCGASFSRANHLTRHMTLHRAVLVHQCDRCEKAFATDEHLKVHVEEEHINKPYVCTVCNKPFSRGEHLIRHLKVHQNTTDKDTNLKCSICETSFTRSDHLARHTKIHLLQDKRHVCGECGKAFNRLDNLKTHQRIHTGEKDTSKLHLCIYCGKEFNNSSNMIVHMRRHTGERPYKCSECGKGFPRSHDLKCHERTHSGEKPYLCTLCGKSFNKSNKLLRHSRVHTGERPYVCNICSRAFTQSNDLALHMRRHTGARPYACGVCPARFIQSGQLKTHRRTTGHWMDVQPDLKGGHRVEPVTPAHEPMPIRFKVHRAMKKEQNILEQAGLMTTQPSTSEGISMNNQIPTIQSEPHRIVMGIMGNLKIPGPDSSIQPLLIDSAKLAELQNAGLVNLPSVIQTTNGDEIKLKSEVGNFGMPQEIEKREGNTNNSYQDDVVIYSSVGHTSTTYTSSENFNFQSFH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01106593;
90% Identity
iTF_01106593;
80% Identity
-