Basic Information

Insect: Frankliniella fusca
Gene Symbol: MBD-R2
Assembly: GCA_029379305.1
Location: JAHWGI010001033.1:1599082-1606692[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.8e-16 1.7e-12 47.5 0.2 5 73 361 428 357 432 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.8e-16	1.7e-12	47.5	0.2	5	73	361	428	357	432	0.93

Sequence Information

Coding Sequence: ATGTCTGACAGAAGAGTAAAGTCAAAGCAAAGTTCCTCTGCTGATCCCAAACTGGCGGATATAGAATCTCAGAGTGATAGATCCAAGCCTGTGGAAAGGCGTTTTAAAGTTGGAGAACAGGTTATGGCAACTTGGACTAACAATCGAAAGTATCCTGCTACTATTGCCAATCACCAACCGAATGACCGTTACGAAGTAATATTCTATGACGGGTTTGCCAAATCTGTGAGAGGCAGCAAGATTTCTAAAATGAAAGACTCTGATTTGATGTCAAAGCATCCAATGAGTCATTTGAGTAGCAAGGTGCCACCCAGCCATAGTAATCATCTCCAAATGCAACCCCAGTTTTTATCGCAACACTCTATTCACAATAATCAACTAAAAAGTCAGCTGTTAAATGGCAGTTTAAGTAATGGGAGCCCTATGCTGTCATCAAAATCAAGCCTTCAAGTTGGCCATAGCCAACTTGAGAAACAACTTCTTCAACCTTCACCACTCCCTGGAAGTCTTCATTATCCGTCTCAAAACTCTTCTGTCAATGGTTTGTCACCTTTTGGTGAGAACATTGGTACTAAGGAACAaaggagagaaaggaaaagaaaacacaatgTGAAAGAACTCTTCTCGACAAAGCGACCCAGGGGAACTGAAAAAGTACCATCCTCTAAAGTGCGGGCTGATAAGAAATCTCTTGCTGGAGCCTTCCAAGACTCTTCAGCTTCTTCAGGGTCAACGCCAAGTAACAATGATCATCGTCTAGGTAATGGACTGTTGCTAGGTGTTGATCCGATGTTTCCTGCAAATCCTATGAAGGTAGAGGGAATTCCACCTCCATCTTTGAGTGTCAAAGATAAATCCTTCTCAGATCTTTCTGAAACTGATGGAAAGAAGAAGCGGAAAAGGTTAAAGAAGAAGCAAGATGGATTTGGCTCTGACACCACAGAACTCTCCTCATCCCTTAAACGCTCCAAACCTGCATCATCTGATGATGATGAATGTAGCATTCAGTGGACTAATGGGGAGCCTCAGGGTGAAGCTGCCTATGTAATTGAAAGCGCTGAGGGATTGAGAAAATCCATTATTGTAGATGATCGAAGGTTGCCTGTAGGCTGGAGCAAGCACGCAATCCGTCGCCAAGGTGGAACGTCAGCAGGAAAGTGGGATGTCTTTTTAGTGAGCCCGAGGGACGGGCGCAAGTTCCGTTCTCGCAACGAACTTCGGTCATACCACGATGAACGTGGTCTACAGTTCCAAGTGGAGCGTTTTGATTTCTCCCTTGGTCGCAAAAAGATGTATCGTCAgaaagctgcagcagcagccagggcaGCTGCTCAAGAAGATAGaCCCGATTCATCTTCACCAGCTCCAAGTGCTCAAGGCTCAGAGTCTTTGAATGTACCTCTGTCTCCATCTTCCTTGGCTGATCATTCAGCAGCACAAACATCAGCTCTTCATCCTCCTGCTCCTCACTCAATGACTCCCCAAGTGGCTGCCCATGGTGTCCAGCGTGTCAAAACTCTGCTTCCAAGGcgaacatcatcatcatcaggaTCTCCGAACCGCCGAGTACTCTCGCCACCTCCACCTCATGCAATCACTCCTCAGCCTATTATGCCTGTCTTCCCTTCAATTGAATCTCTAAACAAAAAGAGTTTGTCTGCTGGTAGTGATGGGTATATATGTCCTAAAGATGGTTGTGGGAAGAGATTCAGAAAGGAAAATTTACTTCAAATGCACATCAAACATTATCATCCCGAGTACACTGCTTTCATGGGCTCCACTCCCAATGTTGCTGATCTTGCATATGCAAGAACGGTTGGTGAGTCAGCAACTGATGCTCCAAACAGAAACAGGCCAGGTCAAAGCTCATTCATGGAGAAACTAGAAAAGATTTCTCGCATGGAGGCTAATCGGAAagctggaggggagggtgtaGCAGAAGTGCCTAGCAGTCTGGAGGCCCGGTCCCCTACCCTGGGACAGTTGCTGAAGAAAGGCCCAATGCGCAAAGACTCTCTGGATGGCACCACTGCAGCAGCACAAGCTGCTGCAGCCTGGATGGTTGAAACTGCGAGTGATTCAGCTTCTAGCCATATTCCATTACCTGACTCTTTAAGTGACAAAGCAAACCTTATTTCCCAAAGTGGCGCTGCAGAAACTGCCTTGAAAGACAAGATGGAGTGTTTGAGCAGGCCTTTGTCAAGAGCTGCTGGTCTTCCTTCTGACTGTGACCAAGACTCCTTCACTGAACAAAATGGTAACAGAAGCCCATGGAAAGGAGGAAGTCATGATGGATTAATCTCAGCCAGTGCTTCGTCAAGCCCTGTTACTATTCAACCTCCTCCATCATATTTCTacagcaaaaagaaaaagaatcgaATGCCAGCTGAAAAACAGAACTCTCCACCTATTAAACTTGAGGGAGGTAAACCAGTTACCCCACCCATGGAACACTTGCGCCGAGAAGAGCTTATCAACTGTACTTGTGGCTTCACGGAAGAGGATGGACTCATGATTCAGTGTGATTTATGTCTTTGTTGGCAACATGGGCTTTGTAATcaaattgaaaatattgaagATGTACCCCAGAAATATGTATGCCAGATTTGTCAAAATCCTATCCGTGAGCGCAAAAGCCGACATTTCATCCATGATCAAGATTGGCTTAAAGAAGGAGTCTTGCCAAGCCTCTCATTTACGGTGAAGGACTCTGAAAAAGTTCAGCAGCGTGAGGACATATTGAAAAGATCTCATGACCTTTGCTCTTTGTTACTTTTGACTCAAAAAGTTATTCATAGTCTCAGAGTCAAAGTTCACATTGCAGAACAAAAAGATCATCCCAAACTTTATCTTTGGGCCAATAGCTGGCAGACAGAATCCATGGGATGTCCCACACCTCCCTCATCTCCTATGCCAGAGGCAGATCAAAAGCAAGAAAATTTTGGTGTCATGGGGAAAGGCAAGAGCCTGCTTCAGGAGGCTTTGCTAAATGGCAGTCCccttcaacagcagcagcagcaacagaacTTCTCTCAACCTCTTCCGTCTGTGGATGCTCCGAGAATACCTCAACCCGAAGCACCTATTGACCCCAGTGAATGTCGACTCAAACTATTGGATCACATTGAGCATTACCAAACACTAATTGATGCTCGTCTCACTACTCTGGAACAAATGATTGATGAGCTGGAACATGAAGATCCCTCTCTCCTGGATGGTAAACATTCTGATCCAGGTCAAACAAGTATCAAACAAGgTGTGGATGCAGAGGAGACTAACCAGTCAGAGGAAGATTCTGCTCTTGATTTCCTGCCACAAACAAAGGAGACTGTTCAAATGATCTTACGGGACTTATTGAATCTGAGGAAAATATCCATGTTCTGCTAA
Protein Sequence: MSDRRVKSKQSSSADPKLADIESQSDRSKPVERRFKVGEQVMATWTNNRKYPATIANHQPNDRYEVIFYDGFAKSVRGSKISKMKDSDLMSKHPMSHLSSKVPPSHSNHLQMQPQFLSQHSIHNNQLKSQLLNGSLSNGSPMLSSKSSLQVGHSQLEKQLLQPSPLPGSLHYPSQNSSVNGLSPFGENIGTKEQRRERKRKHNVKELFSTKRPRGTEKVPSSKVRADKKSLAGAFQDSSASSGSTPSNNDHRLGNGLLLGVDPMFPANPMKVEGIPPPSLSVKDKSFSDLSETDGKKKRKRLKKKQDGFGSDTTELSSSLKRSKPASSDDDECSIQWTNGEPQGEAAYVIESAEGLRKSIIVDDRRLPVGWSKHAIRRQGGTSAGKWDVFLVSPRDGRKFRSRNELRSYHDERGLQFQVERFDFSLGRKKMYRQKAAAAARAAAQEDRPDSSSPAPSAQGSESLNVPLSPSSLADHSAAQTSALHPPAPHSMTPQVAAHGVQRVKTLLPRRTSSSSGSPNRRVLSPPPPHAITPQPIMPVFPSIESLNKKSLSAGSDGYICPKDGCGKRFRKENLLQMHIKHYHPEYTAFMGSTPNVADLAYARTVGESATDAPNRNRPGQSSFMEKLEKISRMEANRKAGGEGVAEVPSSLEARSPTLGQLLKKGPMRKDSLDGTTAAAQAAAAWMVETASDSASSHIPLPDSLSDKANLISQSGAAETALKDKMECLSRPLSRAAGLPSDCDQDSFTEQNGNRSPWKGGSHDGLISASASSSPVTIQPPPSYFYSKKKKNRMPAEKQNSPPIKLEGGKPVTPPMEHLRREELINCTCGFTEEDGLMIQCDLCLCWQHGLCNQIENIEDVPQKYVCQICQNPIRERKSRHFIHDQDWLKEGVLPSLSFTVKDSEKVQQREDILKRSHDLCSLLLLTQKVIHSLRVKVHIAEQKDHPKLYLWANSWQTESMGCPTPPSSPMPEADQKQENFGVMGKGKSLLQEALLNGSPLQQQQQQQNFSQPLPSVDAPRIPQPEAPIDPSECRLKLLDHIEHYQTLIDARLTTLEQMIDELEHEDPSLLDGKHSDPGQTSIKQGVDAEETNQSEEDSALDFLPQTKETVQMILRDLLNLRKISMFC*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00733117;
90% Identity: -
80% Identity: -