Basic Information

Insect: Formica exsecta
Gene Symbol: zfh1
Assembly: GCA_003651465.1
Location: NW:1537218-1558832[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.59 40 4.3 0.4 2 23 76 98 76 98 0.89

2 7 1.7e-05 0.0011 18.6 0.6 2 23 117 138 116 138 0.97

3 7 4e-06 0.00027 20.6 7.8 1 23 147 169 147 169 0.99

4 7 8.1e-06 0.00055 19.6 1.3 1 20 175 194 175 196 0.96

5 7 5.5e-05 0.0037 17.0 4.7 1 23 640 662 640 662 0.95

6 7 5.1e-05 0.0034 17.1 7.1 1 23 668 690 668 690 0.98

7 7 0.0011 0.072 12.9 4.3 1 21 696 716 696 717 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.59	40	4.3	0.4	2	23	76	98	76	98	0.89
2	7	1.7e-05	0.0011	18.6	0.6	2	23	117	138	116	138	0.97
3	7	4e-06	0.00027	20.6	7.8	1	23	147	169	147	169	0.99
4	7	8.1e-06	0.00055	19.6	1.3	1	20	175	194	175	196	0.96
5	7	5.5e-05	0.0037	17.0	4.7	1	23	640	662	640	662	0.95
6	7	5.1e-05	0.0034	17.1	7.1	1	23	668	690	668	690	0.98
7	7	0.0011	0.072	12.9	4.3	1	21	696	716	696	717	0.96

Sequence Information

Coding Sequence: ATGAGCATGACTCTCGTCCGAAATTCGTTCAAGGGCTGCAGCGAGGACGACGCAGGTGTCGTGGATACAAAGGTGGGCGGAGGTTGCGCGGGTGAAGCGCCAACCGCAGGAGGTGGTGATGCTGCCGGAGATGGAGGTGGTGGTAGCGTTGGAACGCGCGGGGATGGTGGCGGCGACAGCGAGGGCGGATCATCCGCgaagcagcagcagcagcagagTGGCGAAAGGTGCCCTCAGTGCGGCATCCTATGTCGGGACGTCCGTGTCCTGCAGCTTCATCTCGAGGACACGCACAAAACGTCCTATACCATCGATAAGCACGATCTCAACGCCCAGTTCTCCCAAGTGTCCTGCAAAGTGTGTAGCAAAACCTTTGCCAACGTCTACCGGTTACAGAGGCACATGATTAGTCATGACGAAAGTGCCGTTTTACGAAAGTTCAAGTGTCCCCATTGCGAGAAGGCCTTCAAGTTCAAGCATCACCTTAAGGAACACCTGCGCATTCACAGCGGTGAGAAGCCATTCCAATGCAACAATTGCGGCAAACGTTTCTCTCATTCTGGTTCATATTCGAGCCATATGACGGCAAAGAAGTGTTtgataatgaatttaaaaaagtcaaGACAAAATACCATAAGTAATGTCGATCGGGGACCGAAAAAAACGCATCAACCGTTATCTGGACGACGCGAGGTTGATCTTCTGACAGCTAATAATAACACGTTCCTACCGATCTTGCCGAAATTGTCACCTTCGGATTATCAAGAAATACAAAGGGAAGCTGCGGCAGgTATCTATGATGTGCCGACCTTGCTGCCTCAGATGATGGGGTACGGAAATTATATCCTGCAGTCTTCGATAGGCAAGCTGCTGAACCAATTGCACTCTAAACGGCTCGACGAAATCGCCGAACAGTTTGAGACGCATCGAGAAGTGATGAGTCCATCGACAGCGGATTCCGAGGGAACCGAAGGCACTGAGGGTAAGGAGTCCCCTGCACCAGCGGATCCAATGCAAAGTCTCGATGCTGTTCGCCGAATTCTGGAGACCGTAAATACTTCCGTGACGAAACAGCTACTTGAAGCGAATGTGCGAAAACTCTCCACGTCTCCGGCTACAATGAAACGAGAACTTGAGGAAGATTATCAGGATCAAGATAGCGAAATGTCCAGTGAGATGACACATTGTCCAGACTGGGCCGCATTAGACCAATATGACTCGCAAAGCGAGGGTCTGGCTGCGAAATTAGAAAATGTCAATCACCCGACATCGAGATCATCCAGTAAGAGAAAGATGGAGGACAGTTCTGAGGGAGATTCAGAGGATGAGGATGAGGGCAACCACACTCACAACGATAACGGTAGAAGGGTTAGAGCTAGATCGCTTATAGATGATGAACAATTGGCCATTCTGAAAGGTTACTATTCCATCAATCCGCGACCTAAAAAGGAGGAAATCATCATGATTgctaattgtattaatttcccTACTCGTGTGGTACAGgtTTGGTTTCAAAATTCTCGGGCCAGGGATCGAAGAGAATCAAAAATGCCACCGGCCTTGGTACCTTTAGTCTTGGGAAATCAAACTGTTATCGAGCAGCCTTTGGATTTGTCTAAAAAGGAAGCATTTGTTGCATCAACGACCAAAGAAAGTGATATATCGAGCAGAAATATCTCGTCTCCTTGCGAGCAAAAGGACGATAATTCAGTCTCGAACGTCGACAACGACGATCTCGAGGATTCGCCTCTTGTCATAGATGAAGAAACTGCTATTGATCCTATTGAACCAAAGCGTACACCTACAAATGGAGAGATAATCACAAagagacaaaatcaaataaatgcgaaaagtGAAAGTGAAGCTGCACCTCAATCGGAAGCAACCCCTGTAGCAGCAGAAACTGAGCAGGGTCTTTATTCCTGCGATCGATGCGACAAAACATTCTCCAAACACAGTTCTCTTATGAGACACAAGTATGAACATTCCGGGCAAAGGCCGTACAAATGCGTGGAGTGTCCAAGAGCGTTCAAGCACAAGCATCATCTGACTGAACACAAGCGGCTACACAGCGGCGAAAAACCTTTCCAGTGCTCCAAGTGCCTAAAGCGCTTCTCTCACTCCGGCTCCTATAGCCAGCACATGAATCATCGTTACTCTTATTGCAAGCCCTACAGAGAATAG
Protein Sequence: MSMTLVRNSFKGCSEDDAGVVDTKVGGGCAGEAPTAGGGDAAGDGGGGSVGTRGDGGGDSEGGSSAKQQQQQSGERCPQCGILCRDVRVLQLHLEDTHKTSYTIDKHDLNAQFSQVSCKVCSKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFQCNNCGKRFSHSGSYSSHMTAKKCLIMNLKKSRQNTISNVDRGPKKTHQPLSGRREVDLLTANNNTFLPILPKLSPSDYQEIQREAAAGIYDVPTLLPQMMGYGNYILQSSIGKLLNQLHSKRLDEIAEQFETHREVMSPSTADSEGTEGTEGKESPAPADPMQSLDAVRRILETVNTSVTKQLLEANVRKLSTSPATMKRELEEDYQDQDSEMSSEMTHCPDWAALDQYDSQSEGLAAKLENVNHPTSRSSSKRKMEDSSEGDSEDEDEGNHTHNDNGRRVRARSLIDDEQLAILKGYYSINPRPKKEEIIMIANCINFPTRVVQVWFQNSRARDRRESKMPPALVPLVLGNQTVIEQPLDLSKKEAFVASTTKESDISSRNISSPCEQKDDNSVSNVDNDDLEDSPLVIDEETAIDPIEPKRTPTNGEIITKRQNQINAKSESEAAPQSEATPVAAETEQGLYSCDRCDKTFSKHSSLMRHKYEHSGQRPYKCVECPRAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01421778;
90% Identity: iTF_00110078;
80% Identity: iTF_00729956;