Agra002480.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Anoplolepis gracilipes
Gene Symbol
zfh1
Assembly
GCA_031304115.1
Location
JAPWJP010000294.1:1888237-1894462[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 0.6 1.1e+02 4.8 1.5 2 23 73 95 73 95 0.91
2 7 2.5e-05 0.0046 18.6 0.6 2 23 114 135 113 135 0.97
3 7 6e-06 0.0011 20.6 7.8 1 23 144 166 144 166 0.99
4 7 0.00013 0.024 16.3 1.8 1 20 172 191 172 193 0.96
5 7 8.2e-05 0.015 17.0 4.7 1 23 637 659 637 659 0.95
6 7 7.5e-05 0.014 17.1 7.1 1 23 665 687 665 687 0.98
7 7 0.0016 0.29 12.9 4.3 1 21 693 713 693 714 0.96

Sequence Information

Coding Sequence
ATGTCGATATCAGTTATAAGGCACACAGGCTGCAGCGAGGACGACGCAGGTGTCGTGGATACAAAGGTGGGCGGAGGTTGCGCGGGTGAAGCGCCAACCGCAGGAGGTGGCAATGCTGCCGGAGATGGAGGTGGTAGCGGTGGAACGCGCGGGGATGGTGGCGGCGACAGCGAGGGCGGATCATCCACgaagcagcagcagcagcagggTGGCGAAAGATGCCCTCAGTGCGGCATCCTCTGTCGGGACGTTCGTGTCCTGCAGCATCATCTCGAGGACACGCACAAAACGTCCTATACCATCGATAAGCACGATCTCAACGCCCAGTTCTCCCAAGTGTCTTGCAAGGTGTGCAGTAAAACCTTTGCCAACGTCTACCGGTTACAAAGGCACATGATTAGTCATGACGAAAGTGCCGTTTTACGAAAGTTCAAGTGTCCTCATTGTGAGAAGGCCTTCAAGTTCAAGCATCATCTTAAGGAACACCTACGCATTCACAGCGGTGAGAAGCCATTCCAATGTAACAATTGCAGCAAACGTTTCTCTCATTCGGGTTCGTATTCGAGCCACATGACGGCAAAGAAGTGTTTGATAATGAATCTAAAAAAGTCAAGacaaaatactataaataatgtCGATCGGGGACCGAAAAAGACGTATCAGCCGTTATCGGGACGACGCGAGGTTGATCTGCTGAcagctaataataatactttcttGCCGATCTTGCCGAAATTGTCACCTTCGGATTATCAGGAAATACAAAGGGAAGCTGCGGCAGgtATTTATGACGTACCGACCTTGCTACCTCAGATGATTACGGGATACGGAAATTATATCTTGCAGTCTTCGATAGGCAAGTTGCTAAACCAATTGCACTCTAAGCGGCTCGACGAGATCGCCGAGCAGTTTGAGACGCATCGAGAAGTGATGAGTCCATCGACAGCGGATTCCGAGGGAACGGAAGGTACTGAAGGTAAAGAATCTCCCGCGCCAGCGGATCCAATGCAGAGTCTCGATGCTGTTCGGCGAATTCTGGAAACCGTAAATACTTCCGTGACGAAACAGCTACTTGAAGCAAATGTACGGAAGCTCTCCACGTCTCCGGCTACAATGAAGCGAGAGCTGGAGGAAGATTATCAGGATCAAGATAGCGAAATGTCTAGTGAGATGACACATTGTTCGGATTGGGCTGCATTAGATCAATATGACTCACAGAGTGAGGGTCTAGCTGCGAAATTAGAAAATGTCAATCATCCGACATCGAGATCAACCAGTAAGAGAAAAATGGAGGACAGTTCTGAGGTGGATTCGGAGGATGAGGATGAAGGCAACCACACTCACAACGACAACGGTAGAAGGGTTAGAGCTAGGTCGCTCATAGATGATGAACAATTGGCCATTCTGAAAGGTTACTACTCCATCAATCCGCGACCTAAAAAAGAGGAAATCATCATGATCgctaattgtattaattttcctaCTCGCGTGGTACAGgttTGGTTTCAAAATTCTCGAGCCAGGGATCGAAGGGAATCAAAAATGCCACCGGCTTTGGTACCTTTAGCCCTGGGAAATCTAACTGTTGTCGAGCAGCCTTTGGATTTGTCTAAAAAGGAAGCACTTGTATCAACAACTATAGAAAGTGAAATATCGAGCAGAAATACCTCATCTCCTTGCGAGCAGAAGGACGATAATCCAGCTCCAAACGTTGACAACGATGACCTCGAGGATTCGCCTCTCGTTATAGACGAAGAGACTGCTACTGATCCTATTGAATCAAAACGTACGCCTACAAATGGAGAGATAATAACAAagAgtcaaaatcaaataaatgcaaaaagtgAAAGTGAAGCTGCACCTCAGTCGGAAACAACCCCTGTAACAACAGAAACCGAGCAAGGTCTTTATTCCTGTGATCGGTGTGACAAAACATTTTCCAAACACAGTTCTCTTATGAGACACAAGTATGAACATTCCGgGCAAAGGCCGTACAAATGCGTGGAGTGTCCAAGAGCGTTCAAGCACAAGCATCATCTAACTGAACACAAGCGGCTGCACAGCGGCGAAAAACCTTTCCAGTGCTCCAAGTGCCTCAAGCGCTTCTCTCACTCCGGCTCCTATAGTCAGCATATGAATCATCGTTACTCTTATTGCAAGCCCTACAGAGAATAG
Protein Sequence
MSISVIRHTGCSEDDAGVVDTKVGGGCAGEAPTAGGGNAAGDGGGSGGTRGDGGGDSEGGSSTKQQQQQGGERCPQCGILCRDVRVLQHHLEDTHKTSYTIDKHDLNAQFSQVSCKVCSKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFQCNNCSKRFSHSGSYSSHMTAKKCLIMNLKKSRQNTINNVDRGPKKTYQPLSGRREVDLLTANNNTFLPILPKLSPSDYQEIQREAAAGIYDVPTLLPQMITGYGNYILQSSIGKLLNQLHSKRLDEIAEQFETHREVMSPSTADSEGTEGTEGKESPAPADPMQSLDAVRRILETVNTSVTKQLLEANVRKLSTSPATMKRELEEDYQDQDSEMSSEMTHCSDWAALDQYDSQSEGLAAKLENVNHPTSRSTSKRKMEDSSEVDSEDEDEGNHTHNDNGRRVRARSLIDDEQLAILKGYYSINPRPKKEEIIMIANCINFPTRVVQVWFQNSRARDRRESKMPPALVPLALGNLTVVEQPLDLSKKEALVSTTIESEISSRNTSSPCEQKDDNPAPNVDNDDLEDSPLVIDEETATDPIESKRTPTNGEIITKSQNQINAKSESEAAPQSETTPVTTETEQGLYSCDRCDKTFSKHSSLMRHKYEHSGQRPYKCVECPRAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE