Basic Information

Transcription Factor Domain

TF Family: CBF
Domain: CBF_beta domain
PFAM: PF02312
TF Group: Beta-Scaffold Factors
Description: Core binding factor (CBF) is a heterodimeric transcription factor essential for genetic regulation of hematopoiesis and osteogenesis. The beta subunit enhances DNA-binding ability of the alpha subunit in vitro, and has been show to have a structure related to the OB fold [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 3.2e-15 3.6e-11 42.3 0.1 1 27 34 60 34 75 0.95

2 2 5.5e-34 6.2e-30 103.4 0.0 93 163 142 212 139 216 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	3.2e-15	3.6e-11	42.3	0.1	1	27	34	60	34	75	0.95
2	2	5.5e-34	6.2e-30	103.4	0.0	93	163	142	212	139	216	0.96

Coding Sequence: ATGATGCATACCATGAGCGAGCACGCCGGCGTCGGCGTGCTGCCCTTTGACGGGATGGGTCTCTATGAGCAACCGCGACCACCCCGGCTTGTTTTCAAGATGCCGCGGGTCGTACCTGACCAGAAGTCCAAATTCGAGAGCGACGAGCTTTTTAGGAGACTGAGCCGCGAGAGCGAGGTGAGTCCGCTGGGGAACAcCCACGTTCGTCTCAAGACGCATCCGAAGTCCTTCCATCATCGAAACCTCGTCAAGCCAGAAATCTTCTCCATcaatctaattgtaagaccATCCAAGACCTTTCCAAGGAGCATCCCAATCATCCACCGAGACCGAGATCGAGATCGAGACCGACGAGTATCGACGTTTCCACACGTGGACACAGCATCAGCACTGAAATTTTCCGTCCCGCCGATTGCGGTGTTTCAGGTACACCTGCGCTCGCATCTCATCATGAACGGCGTATGCGTGAGGTGGCGCGGTTGGATCGATCTGGATCGGCTCGACGGCGTCGGATGCCTCGAGTACGACGAGGAGCGCGCCGCTGAGGAGGACGCGCTGTTACGGGATCAACTCGAGCGTTACAACCAGCGGCTGCGCGACTTCGAGGAGAAGCAGCGTGCTTATCGTAGCGGCGCGGCATCAGCCGCGCAACCACCGCATCTCAATCATCATTATCACCACGACACGCATCACGCGGCGAGCCATCACCATCACCATCACGGCCACCACAGCCGACACGTGGGCGGCGCGGGCGCCACCGGCGCCACCGCCACCGGTATCGAACCCCACCTGCCGCATCGCCAGGACCCCGACATGGAGGTGCGACTGCGAGCCTACTGA
Protein Sequence: MMHTMSEHAGVGVLPFDGMGLYEQPRPPRLVFKMPRVVPDQKSKFESDELFRRLSRESEVSPLGNTHVRLKTHPKSFHHRNLVKPEIFSINLIVRPSKTFPRSIPIIHRDRDRDRDRRVSTFPHVDTASALKFSVPPIAVFQVHLRSHLIMNGVCVRWRGWIDLDRLDGVGCLEYDEERAAEEDALLRDQLERYNQRLRDFEEKQRAYRSGAASAAQPPHLNHHYHHDTHHAASHHHHHHGHHSRHVGGAGATGATATGIEPHLPHRQDPDMEVRLRAY

Sequence clustering based on sequence similarity using MMseqs2