Fcup006806.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ferdinandea cuprea
Gene Symbol
BCL11A
Assembly
GCA_963576555.1
Location
OY754958.1:119954916-119972986[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 6 0.034 5.1 8.6 2.3 1 23 223 246 223 246 0.95
2 6 4.9e-05 0.0074 17.5 1.6 1 23 593 615 593 615 0.98
3 6 0.014 2.2 9.8 5.5 1 23 621 643 621 643 0.99
4 6 1.3e-07 2e-05 25.6 2.9 2 23 871 892 870 892 0.97
5 6 9.4e-06 0.0014 19.8 3.3 1 23 898 920 898 920 0.99
6 6 1.7e-05 0.0026 18.9 0.4 1 22 928 949 928 949 0.97

Sequence Information

Coding Sequence
atgaaaaataaaacaataacaatgcTGTCTGTTAGTGAAGATGCTGGATTTCGTTCGCTTAGCCATTCAGATTCTTCTGATGCGGACCCAGCTGCTCAGGACATTTTAACCTGCGGATCATGTCAGAAAGCCTTTGCGTTATCTGATATTGTTCGATTTATTCAACACAAAGTTTTACAATGCAATAAGGAAAACTATGGACAATGTTTAACACAAGGTCCTGCCAGTGACAGAGACGCCGATGATGGGCGGCCTCTTAGTCTAGTTAATCGTAGACCATCCATATCAGCTCCGATAACAAATCGTAAGCCATCCGGAACCCGAATTCATACACCGCCTCCTAGTCCAGCTGATTTGTTAGCCGATGGAGCATCGAGCACTCCAAAGCGGCTTGTTGATGaaaatgatAACACAACACCCAAGGGTGACAGTTCATCAACAAACCGAACTGAAGATGAACAAACAGAAAAATCCTCAAACGATACAGAAAACGAAAAGCCTAGCAGTGTACTGGACATCAAGCGAGAGCATACAGATTGCGGCCTAAATCTGGAAGAAGATAGTCAATCACCCTTAGCGGTCAATGATGGTCAGCCGCCCagtaaaaaaccaaaaattgaaGTCGCTGACGCCGAATCAAATACTTTGAATAGTGAGCCCAGCAACTATACTTGTTCCACCTGCAAAACACGATACAACTCCGCCTGGAGACTGATCCAGCATGTGCAGCACTCGCATGGAGTTAAAATTTACGTGGAATTCTCATCATCGACATCGCCATCGTCGTCGGCGTCCTCATCGCTGTCGACGTCCACATCGTTGTTATCTTCGTCCGCAAATTCGTTATCTCTGGGTCATTCGACACAGAAACTGTTGGGTGGTGTTGCCAATAGTAcaatcaacaacaacaccagctgCGCCAGTTCCCTTTGCTCGTCAACGTCCCCGGTTAGCCAAAGTAAGAACATTATTGAAACACAACAGcaccagcaacaacaatctCAGCAGCAAAACAGCCTAACCACAGCCATGCAGAATGCTCAAAATTTAGCCGCGGCGGCAGCAGCTGGTATGAGACATCATCCTTTGTTACCTCCACCAGATATGCATGCAAATCCTTTCAACTTGCTGCGAATGCCATTGCCGCCCCTAGCACAAGGTCCAGTAGTTCCTCCGGTTGCGCCGCTTTTCTCGCGACCACATGCGGCCGATCACTACCGCATGGAACAACTCGTTTCGGAGCAATTTCGCCACCATGGCCTTAATTTGGCGGCAGCAGCTGTAGCTGCAGCCAACTCACTAGCACCCCATTCGAGCCAATCCTTCAATGCGGCAGTTAACCACTCCGCAAGCAATAAAGAGCGCCCGCCATCGTCGAGCAGTAGTCACAGTTCGATACCGCCACTACAGCAGACGCGCCTCAATAATAGACAGCCAAACAATCTTTCACTTGAACCGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCAGGAACAACAAGTCCTGGAGCTGGAAACACTGGTAACTCGAACTCGCCGAGTCCCAGGCAAAAGCAGTCGCCGTCTAATTTCGCGAGCCCAACACCCTCTCAGCTACCTCCAACACCGGTCACAAGCAATTCCCGTCCCCAGAGTTTGACTCCTCCAGAGAAGAGCTGCACTATACTCGGTGAAACTGATCTTGGAAATGGTACCAACCACCTAAATACAACTCCTCGCTCTGCGTCGACACCGCCCTCCAAGCCTAGTCAGGACAGTGGTGCCGCTGTATACTCGTGTGACTTCTGCGAAAAGAACTTTCGCTTTGAGAACAACCTAATCATTCACCGTCGTATGCATACAGGGGAGAAACCGTATAAGTGTGTACAGTGCGAATTCGAGTGCTCTCACATCAACAAACTGAAGCGTCACATGAAAGTGCACATTAAACCTGAAGATGGCGCTAGCAACGCCGGCTCAGTGGAGACCCTCGATGGTGAAGACTCTGGCGAGGAGGATATGGCGGAAGAAGAAATTCTCGATGAAGACGAAGATGATGACATGGAAGACGGAGAGGATGGCGAATATGAAGCTGAAGACCTCAGCGTAAATAGCCGAACAATGGACGTTAAGCCAGGAATGAATATGGGCAATCCTACGTCCAACTCATTGGTCGGCGAATTGATGGATAAGTTTGGTCTGTCCAACATCGCCCAATACTCCGAGGCCTATAAACAAGCCCTCCAAGAGTCTGGTAATGCAATGAAGATGCAACTCAACAGCAAGGACtgcgacaacaacaacgacggTGCGTCTCTACAAAAGTTAAACGGCCTGCCAGCAGCTCTGCGTCTCCGACAAGAATTTGCCAAGAGCATGCTTCATTCGCCCAACCAAGGACATCCACAATCTCAGGTTGCCCCGCTATTTAACCCCTTCGAGAATCCCTTCGAGATGTCGAAAAGAATGAAAATGGAAAGCGCCGAGTGGTGGGGAATGTCCGCCCTCCATCGAAATGAATCCCTCTTCGAAAATCTCAAAATGAAACCTCTCTCATCTCTCGGCTCCAACAGTTCGCAGCTACTGCAAAATCCTCTCGTCAAAAAGGAGAGTAAACGCAACGACACCTGCGAATACTGCGGCAAAGTCTTCAAGAACTGCTCCAATCTGACCGTCCACCGGCGCAGTCACACTGGCGAGAAGCCCTACAAGTGCGAACTCTGCTCATACGCATGTGCCCAATCGTCGAAATTGACACGTCACATGAAGACACACGGTCGCACTGGCAAAGACGTCTACCGATGTCGATTCTGTGATATGCCATTTAGTGTTCCGTCAACACTTGAAAAACACATGCGAAAGTGTGTCGTTAACCAGGGCAAAGCAGCAGCGGTCTCCGCGTCTAATCTCGTCCAAGGTGGACAGCATCCCTCACCATCACCCCTGTCATCGCATCTACCACAAATGCCAATGATTTCGAGCAGCGGCAGTGTGGGCGGACTCACCGCTGACGATGACTCTAGTGCGTCAGTAATCAGTAAAGAAGGGGCATGA
Protein Sequence
MKNKTITMLSVSEDAGFRSLSHSDSSDADPAAQDILTCGSCQKAFALSDIVRFIQHKVLQCNKENYGQCLTQGPASDRDADDGRPLSLVNRRPSISAPITNRKPSGTRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKGDSSSTNRTEDEQTEKSSNDTENEKPSSVLDIKREHTDCGLNLEEDSQSPLAVNDGQPPSKKPKIEVADAESNTLNSEPSNYTCSTCKTRYNSAWRLIQHVQHSHGVKIYVEFSSSTSPSSSASSSLSTSTSLLSSSANSLSLGHSTQKLLGGVANSTINNNTSCASSLCSSTSPVSQSKNIIETQQHQQQQSQQQNSLTTAMQNAQNLAAAAAAGMRHHPLLPPPDMHANPFNLLRMPLPPLAQGPVVPPVAPLFSRPHAADHYRMEQLVSEQFRHHGLNLAAAAVAAANSLAPHSSQSFNAAVNHSASNKERPPSSSSSHSSIPPLQQTRLNNRQPNNLSLEPQMDFYSQRLRQLAGTTSPGAGNTGNSNSPSPRQKQSPSNFASPTPSQLPPTPVTSNSRPQSLTPPEKSCTILGETDLGNGTNHLNTTPRSASTPPSKPSQDSGAAVYSCDFCEKNFRFENNLIIHRRMHTGEKPYKCVQCEFECSHINKLKRHMKVHIKPEDGASNAGSVETLDGEDSGEEDMAEEEILDEDEDDDMEDGEDGEYEAEDLSVNSRTMDVKPGMNMGNPTSNSLVGELMDKFGLSNIAQYSEAYKQALQESGNAMKMQLNSKDCDNNNDGASLQKLNGLPAALRLRQEFAKSMLHSPNQGHPQSQVAPLFNPFENPFEMSKRMKMESAEWWGMSALHRNESLFENLKMKPLSSLGSNSSQLLQNPLVKKESKRNDTCEYCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAVSASNLVQGGQHPSPSPLSSHLPQMPMISSSGSVGGLTADDDSSASVISKEGA