Basic Information

Insect: Eristalinus aeneus
Gene Symbol: BCL11A
Assembly: GCA_955652365.1
Location: OY019132.1:77714628-77730545[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.015 2.1 9.6 2.2 1 23 237 260 237 260 0.95

2 6 4.8e-05 0.0069 17.5 1.6 1 23 641 663 641 663 0.98

3 6 0.021 3 9.2 5.7 1 23 669 691 669 691 0.99

4 6 1.3e-07 1.9e-05 25.5 2.9 2 23 919 940 918 940 0.97

5 6 9.2e-06 0.0013 19.7 3.3 1 23 946 968 946 968 0.99

6 6 1.7e-05 0.0024 18.9 0.4 1 22 976 997 976 997 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.015	2.1	9.6	2.2	1	23	237	260	237	260	0.95
2	6	4.8e-05	0.0069	17.5	1.6	1	23	641	663	641	663	0.98
3	6	0.021	3	9.2	5.7	1	23	669	691	669	691	0.99
4	6	1.3e-07	1.9e-05	25.5	2.9	2	23	919	940	918	940	0.97
5	6	9.2e-06	0.0013	19.7	3.3	1	23	946	968	946	968	0.99
6	6	1.7e-05	0.0024	18.9	0.4	1	22	976	997	976	997	0.97

Sequence Information

Coding Sequence: ATGAGTCCCAAACTAAACAGACCGACACCGCCCCCGACAGCACAACACCAGTCAACGGTCGCCCTATCCTTCGCCACAGATTCAGATTCGTCTGAGGCGGACCCAGCTGCTCAGGACATTTTAACCTGCGGATCGTGTCAGAAGGCCTTCGCGCTATCCGACATCGTTAGATTTATTCAACACAAAGTTTTACAATGCAATAAAGAGAACTATGGGCAATGTCTTACACAAGgtCCCACAAGTGATAGAGACGCCGACGATGGACGGCCTCTCAGTTTAGTGAATCGCAGACCATCCATATCAGCTCCAATAACAAATCGTAAGCCATCCGGTACCCGAATACATACACCGCCCCCTAGTCCAGCTGATTTGTTAGCCGATGGAGCATCAAGCACCCCCAAACGGCTTGTTGATGAAAATGACAACACAACCCCAAAGGGTGACAGTTCGGCAACAAATCGAACAGAGGCCTCCCAAGAGGAGGGCCCACAGACAGCCGAAAAATCGCAAAACGATACAGAAACCGAACAACCAGACACCGGAGGACTGGACATCAAACAGGAACAAATCGATTGTGGCCTCAATCCCGACGATGAGGAGAACAGTCAGCCACCGTCGACGTCCAATGATGGTCAGCCGCCGagtaaaaaaccaaaaattgaaGTTGCCGACGCCGAATCGAATACCTTGAACAGTGAGCCCAGCAACTATACCTGCTCCACCTGCAAGACGCGATACAGCTCCGCCTGGCGACTGATCCAGCACGTGCAGCACTCGCACGGTGTCAAAATCTACGTGGAATTCTCATCGTCTGCGTTAGCGTCATCGTCTACGTCGTCTGCCGCTGCTGCCGCATCCACGTCATCAGCGtcctcgtcatcatcgtcactggcctcgtcatcgtcatcgacGTCCTCGTCACTGTCTACGTCCACATCGCTGTTACCCTCCTCGGCAGCGTCCGCAAACCTTGGCTTGTCGGCCCAAAAGATGCACAGCACTGCTGCCAATAGTACAATCAATCAAAACAATAGCTGCGCCAGCTCGCATTGCTCCTCCACATCGCCAGTCAGTCAGAGCAAGGGCgagcagcagccacagcaacagcaacagcagcagcagactcCACAGCacacacagcagcagcagaacagCCTGACAACAGCCATGCAGAACGCACAGAATCTGGCCGCTGCAGCAGCTACCGGCATGCGCCACCATCCACTGCTGCCTCCACCAGACATGCATGCAAACCCCTTCAACATTCTACGAATGCCACTGCCGCCACTAGCACAAGGTCCAGTAGTTCCTCCGGTTGCGCCACTCTTCTCACGGCCGCACGCAGCCGATCACTATCGCATGGAGCAACTCGTTTCGGAGCAGTTTCGCCACCACGGCCTTAATCTAGCGGCAGCGGCTGTAGCAGCAGCCAACTCACTAGCACCGCATTCCAGTCAGTCCTTCAACGCGGCTGTGAACCACTCGGCCAGCAATAAGGAGCGCCCGCCCTCGTCGAGCAGCAGCCACAGTTCCATACCGCCACTGCAGCAAACGCGTCTGAACAACAGACAGTCCAACAACTTACCACACGAGCCGCAGATGGATTTTTACTCGCAGCGATTGCGTCAGCTTGCAGGAACAACAAGTCCTGGAGCTGGAAACACTGGTAACTCGAACTCGCCGAGTCCCAGACAAAAGCAATCGCCGTCGAATTTTGCGAGTCCATCCCCCTCCCAGTTACCTCCGACGCCGGTCACAAGCAACTCCCGTCCCCAGAGCCTCACTCCGCCGGAGAAGGGCGGCAGTCTCGGTGAGACCGATCTGATGGGCGGCGGCAACGGAACAACCCACCTGAACACCACTCCACGCTCTGCGTCCACGCCACCAACCAAGCCTAGTCAGGACACCGGTGCCGCAGTGTACTCGTGCGACTTCTGCGAGAAGAACTTTCGCTTTGAAAACAACCTGATCATCCACCGCCGCATGCACACCGGCGAGAAGCCATACAAGTGCGTGCAGTGCGAGTTCGAGTGCTCCCACATCAACAAGCTCAAGAAGCACATGAAGGTGCACATCAAGCCGGAGGATGGCGCTAGCAACGCCGGCTCCGTGGAGACCCTCGACGGCGAGGACTCCGGCGACGAAGACCTGCCAGAAGATGAAGACATGGCcgaggatgaggatgacgagATGGACGAGGGCGAAGATGGAGACTACGAAGCGGAGGACTTGAGCGTAAACAACAGGACAATGGACGAGAAGCCGGGCATGGGCATGGGAAACTCCACCTCCAACTCGCTGGTCGGAGAGCTGATGGACAAATTCGGTCTCTCGAACATCGCCCAATACTCCGAGGCCTACAAGCAGGCCCTGCAGGAATCTGGCAACGCCATGAAGATCCAACTGAGCAACAAGGATTGCGACAATAACAACAGCAGCTCGTCCCTGCAGAAGCTGAACGGCCTCCCAGCAGCCCTGCGCCTGCGCGAGGAGTTCGCTAAGAGCATGTTGCACTCCCCCAATCAGGGTCACTCCCAGTCGCAAGTCGGCCCTTTGTTCAACCCCTTCGAGAACCCCTTTGAGATGTCGAAGCGCATCAAGATGGAAAGCGCCGAGTGGTGGGGTATGTCAGCCCTCCACCGGAACGAGTCCCTCTTCGAGAACCTCAAGATGAAGCCCCTCTCCTCGCTGGGCGCAAACAGCGCCTCCCTGCTGCAGAGTCCCCTAATCAAGAAGGACAGCAAGCGAAACGACACCTGTGAGTACTGCGGCAAGGTCTTCAAGAACTGCTCCAATCTGACCGTCCACCGACGAAGTCACACCGGCGAGAAGCCCTACAAGTGCGAGCTCTGCTCCTACGCCTGCGCTCAATCCTCCAAGCTGACCCGTCACATGAAGACACACGGCCGCACCGGCAAAGATGTCTACCGATGTCGATTCTGTGATATGCCATTCAGTGTTCCATCAACGCTCGAGAAGCACATGCGCAAGTGCGTGGTCAACCAGGGTAAGGCGGCCGCCGTCAACGCGTCCAACCTCGTCCAGGGAGGCCAGCACCCATCCCCATCATCACTCTCCTCGCACCTGCCTCAGCTGCCCATGATCTCGAGCAGCGGCAGCGTGGGTGGCCTCACCGCCGACGACGACTCCAGCGCGTCAGTGATCAGTAAGGAAGGAGCATGA
Protein Sequence: MSPKLNRPTPPPTAQHQSTVALSFATDSDSSEADPAAQDILTCGSCQKAFALSDIVRFIQHKVLQCNKENYGQCLTQGPTSDRDADDGRPLSLVNRRPSISAPITNRKPSGTRIHTPPPSPADLLADGASSTPKRLVDENDNTTPKGDSSATNRTEASQEEGPQTAEKSQNDTETEQPDTGGLDIKQEQIDCGLNPDDEENSQPPSTSNDGQPPSKKPKIEVADAESNTLNSEPSNYTCSTCKTRYSSAWRLIQHVQHSHGVKIYVEFSSSALASSSTSSAAAAASTSSASSSSSSLASSSSSTSSSLSTSTSLLPSSAASANLGLSAQKMHSTAANSTINQNNSCASSHCSSTSPVSQSKGEQQPQQQQQQQQTPQHTQQQQNSLTTAMQNAQNLAAAAATGMRHHPLLPPPDMHANPFNILRMPLPPLAQGPVVPPVAPLFSRPHAADHYRMEQLVSEQFRHHGLNLAAAAVAAANSLAPHSSQSFNAAVNHSASNKERPPSSSSSHSSIPPLQQTRLNNRQSNNLPHEPQMDFYSQRLRQLAGTTSPGAGNTGNSNSPSPRQKQSPSNFASPSPSQLPPTPVTSNSRPQSLTPPEKGGSLGETDLMGGGNGTTHLNTTPRSASTPPTKPSQDTGAAVYSCDFCEKNFRFENNLIIHRRMHTGEKPYKCVQCEFECSHINKLKKHMKVHIKPEDGASNAGSVETLDGEDSGDEDLPEDEDMAEDEDDEMDEGEDGDYEAEDLSVNNRTMDEKPGMGMGNSTSNSLVGELMDKFGLSNIAQYSEAYKQALQESGNAMKIQLSNKDCDNNNSSSSLQKLNGLPAALRLREEFAKSMLHSPNQGHSQSQVGPLFNPFENPFEMSKRIKMESAEWWGMSALHRNESLFENLKMKPLSSLGANSASLLQSPLIKKDSKRNDTCEYCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRTGKDVYRCRFCDMPFSVPSTLEKHMRKCVVNQGKAAAVNASNLVQGGQHPSPSSLSSHLPQLPMISSSGSVGGLTADDDSSASVISKEGA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00725071;
90% Identity: iTF_00672429;
80% Identity: -