Fcup021960.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ferdinandea cuprea
Gene Symbol
Ibtk
Assembly
GCA_963576555.1
Location
OY754961.1:9966789-9972591[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 3.3e-09 1.3e-06 29.4 0.3 1 86 564 644 564 648 0.87
2 3 8.8e-14 3.3e-11 44.2 0.0 7 104 703 805 697 811 0.75
3 3 1.5 5.7e+02 1.6 0.1 62 109 797 842 787 843 0.81

Sequence Information

Coding Sequence
ATGGATCAATCAAGAGCAGAAAATGTCAGTTCGCAACATTCACCGTACAATATCAACAACTACGAGTACGATTGCacaaaaaagtgcaaaagtCGCTCCCATGGGCAGGAAATTACTGCTGCATTAACAAAACGAGCCGTTGTGGACAGCAAACTAGCAGCTTATATTGCTAAAACATGCTGTAACTTCACTGACATCACAGATCGTCTAGGCCGATCTGCAGTTCATATGGCAGCGTCGGTGGATCGCTACGCAATACTGGAGTGGCTTTTGAATcagGGTGCGATAATCAACAGCAAAGATAAGGAATCGGGTAGTAGTGCCTTGCATCGTGCCATCTACTATGGGTGCATCGACTGCGCAGTTCTGTTGATATGCTACGGGGCAAGCTTAGACCTTCTCGATGATGACACTCGAAGTCCTCTACAAAGCTGTTGCCGGCTTTGTGATAGCAAAACAGTGCCACGTAAAACAGAATTTCAGTCTATAAATAACGAGTTGTTAGTCTGGGGATCTAACAAAAACTACAATTTGGGAATTGGCAATGAAGAAGGTGCTGCTGCTCCTCAATTTATTGACTTCTTTCGCAGGGAGCATATGTCAATAGAATTGATTTCGTTGGGCGCTTTTCACAGTTTATTTGTCAACACTAAAGGCCAACTGTACGCAGTTGGACATGGTAAAGGTGGTCGATTAGgcaatGGGACAGAGAACAGCTTACCAGTGCCAAATAAGGTTAAAGTTCCAATAAAAAATGCCGGCGAGAAGATAATTTGCGTAAGCACATCACGAAAGCATTCTCTAATTCTCACTAATAAGAGCACAGTGTTTGTTTGTGGTCTGAATGAGGACGGCCAGCTGGGAATTCGGGAGGCTCCTGAGAAGTTGTCTGTTTTCAAAGAGGTTGTCACTTTGAGAGACTTTGGTGTCGAGAATCTGACGGCGGTAATAGCCAGGGACTTTCACTCAATTGCATATTCAAGTAGTGTGCTGTATGTATGGGGAACGAATCATGGACAATTTAAGTGCAATAGCAAAAAACCTGTTGTTCCACTGCCAACGCAGGTCTTGCTGCCTGAGGGGACAAACCTTAAATTCGTTGAATCGAATAACTTCGCCATCGCATGTTATACAACAAGTAAAGCAGTGTTACTTTACTATAATCACAAACTAAGGACTATTAAACCACCGCAAATAGAGGCAATAAAAAGCATATCAATCGTTGGAGGCGATAACACAAAAATGGCCAAGGGTTCAGTTTCTGCCTTAAAACTGCTAATTCTCACTGAAACAAATGTCGTTTTCATCTGGTATGAAATGACTCAGCAGTACCTAAGATGCTCCTTTTCGCACATTTTTGTGAATCAAATCGACAAAATCTTCTACAAATCTAATCAGGTGTTAATACTGTCACAGGGCGATGTGTACACAGGCAAATGTCATCAGTTGCCAGTAAAAAACTTTCAGGAAAGCAGTGCAGACGCTTGGTTTACCCATGCCCAGTCGCGCAAGGACATTTGCAATGAACAGAAAATACGCATCGAGCTGAGTCGAATTGCACACATCGATCGAGCGGTGGAGATCTTCTGCGACGACAGCTTCAGTTCGTTTGCTGTGCTGCAGGAGGGATGTACGAAGTATTTTACACTACCGACAATAGTCGCGGAAGAGTACAGCCTAAAAAATCTGTTCAACGATGCGAGCGAGTTTGACGAAACTCATGATGTCACCTTTCATGTGGATGGGGAGGTTTTCTACGCTCATAAGTTTGTCGTGTTTTCGCGATCGGCCGGCCTGAGTGAGATAGTGCAATCGTATCCTGACAAGAAtatctatttaaattttaagggaTTGACGGGAAAGATGTTTCAACTGATCCTGCAGAATATCTACACGAACTATTTCGTGACGGAAGATGATATTGACGATATAGAGCAATCATTGGGGCCAAAGTGTCCCGCTGAGAGGTGGAAGGTACTGCAGTTATTCTTGAGTTTTGTTGAGAAATTTCAACTAAACAGCCTGGCCAACTTTATAAAGAGTCATGAGGACCAACTGCCAATGTCTGTGGATAGATCGAAATATCGCTTTAATCGCCTCAAGCGCAAGGACTATCCTAATCTGTACGACGTCACCATACGATGTGCTGGCGATGTCGAGATCCCCGCTCATAAATGCATTTTAGTCGCTCGGCTAGAATACTTCAGCCTGATGTTGTCCCAAACCTGGTCAGAGAAGAGCGTCATCAATCTGACAACCGTCCCACCAGAGTACATGATTCCCATCGTGGACTTTCTCTACACATCCGATGGCGATCACTTTCGGAAGCAAAACTACTCGGAGGTTTTTCTCTACAACATGATCGTGTTCTGCGATCAATTCTTCATTGAACGCCTTCGGAAGGTTTGTGAAGTTTTGATTTTGGAGAAGATCAACATTCGCAAATGTGGTGAAATGCTAGACTTTGCTTGTCTTTACAACTGTAGCATTTTAAAAACTGGTTGCATGGACTTCATATGTCAGAACTTGTATCGAGTTTTGTCGCAGAAAAGTCTGGAATGCTGTGAGCCGGAAGTTTTAAGCTGCATTAACGCACACTATAGGCGAATGTTCAAGGACGTCTTTGACTATCGGATGATAACTCCCGACTCATCGGCAGTGGACGATGATATTTTGTTGAGCTTTGTTGATGACTTTTACGTCGACTTGGATCATAGGATGGAAGAGACTGTTAAAGCAGAGGCTAAGCACAAACAGCGGGAAAATAGGATAAAGCAAAGTACGAGGCAATATGAAAAGGACGCTATAAACTCTATGAGAGAGTTGAGTTTGCGTGACTCCAAGAGAGACAGTTTCTCAGAGAAATTCAATGTCGAAAAAGAAGCTGAAGAGGCGTCGGCAAAGGTTCATGCTGAATTTAAGACATGGATGAAAGTGTCTGAGAAGAAAGAGACTAAAAAACCAGCGCCAGTCGCAGTTTTGAATGCAAATGAAATTCTGAAAGTTGAACCTAAACCGAGAGAAGAGTTCTTCAGCCTCAATCAACCGGTGGAGAAAGCTATTCCCATACCCACCACTCCGACTACACCCTCGAAAGAATTCAATATCAGTTTGGCGGACATTACACcaataaaaagcgaaaaactCTCTCAAAAGCAAAGGAAACGCTTATCGTCGAATAGCTGGCGAAGTGGTGATCAGCCTGCTATAATCACTCCCACGAAACCGATAGCACTGCCTAAAAAGGAAACACCCAACGCTTGGGGTATTAGTAGCCCGCCAGTGACTGGTAGTGACAACGATCCCTCATCCTTTGCCAATATCATGAGGTCACCGTCAAGCTTTCCACAGGAATCTCCATCAAATCGAATGGGATCGGGACAATCTCCATCGACAAGTGGTACACGATTTACGAATATCCTCCAGGAAGAAAAGCAGCAGCGAGAGTATGTCGATAGGATGAAGAACAAGTCCCTAGTGCTGACGCAAATAGAAGAGACTGCCATTACAGAACTGCGCATTTTTTACAATGTGGACAATGCCGACGATGAGATTATAACAATTGAGCGTATGAAACGACCAGTTACTGTGAATTTTGCCACTTGGCAAAGAAAATCGGAGTATTCATaa
Protein Sequence
MDQSRAENVSSQHSPYNINNYEYDCTKKCKSRSHGQEITAALTKRAVVDSKLAAYIAKTCCNFTDITDRLGRSAVHMAASVDRYAILEWLLNQGAIINSKDKESGSSALHRAIYYGCIDCAVLLICYGASLDLLDDDTRSPLQSCCRLCDSKTVPRKTEFQSINNELLVWGSNKNYNLGIGNEEGAAAPQFIDFFRREHMSIELISLGAFHSLFVNTKGQLYAVGHGKGGRLGNGTENSLPVPNKVKVPIKNAGEKIICVSTSRKHSLILTNKSTVFVCGLNEDGQLGIREAPEKLSVFKEVVTLRDFGVENLTAVIARDFHSIAYSSSVLYVWGTNHGQFKCNSKKPVVPLPTQVLLPEGTNLKFVESNNFAIACYTTSKAVLLYYNHKLRTIKPPQIEAIKSISIVGGDNTKMAKGSVSALKLLILTETNVVFIWYEMTQQYLRCSFSHIFVNQIDKIFYKSNQVLILSQGDVYTGKCHQLPVKNFQESSADAWFTHAQSRKDICNEQKIRIELSRIAHIDRAVEIFCDDSFSSFAVLQEGCTKYFTLPTIVAEEYSLKNLFNDASEFDETHDVTFHVDGEVFYAHKFVVFSRSAGLSEIVQSYPDKNIYLNFKGLTGKMFQLILQNIYTNYFVTEDDIDDIEQSLGPKCPAERWKVLQLFLSFVEKFQLNSLANFIKSHEDQLPMSVDRSKYRFNRLKRKDYPNLYDVTIRCAGDVEIPAHKCILVARLEYFSLMLSQTWSEKSVINLTTVPPEYMIPIVDFLYTSDGDHFRKQNYSEVFLYNMIVFCDQFFIERLRKVCEVLILEKINIRKCGEMLDFACLYNCSILKTGCMDFICQNLYRVLSQKSLECCEPEVLSCINAHYRRMFKDVFDYRMITPDSSAVDDDILLSFVDDFYVDLDHRMEETVKAEAKHKQRENRIKQSTRQYEKDAINSMRELSLRDSKRDSFSEKFNVEKEAEEASAKVHAEFKTWMKVSEKKETKKPAPVAVLNANEILKVEPKPREEFFSLNQPVEKAIPIPTTPTTPSKEFNISLADITPIKSEKLSQKQRKRLSSNSWRSGDQPAIITPTKPIALPKKETPNAWGISSPPVTGSDNDPSSFANIMRSPSSFPQESPSNRMGSGQSPSTSGTRFTNILQEEKQQREYVDRMKNKSLVLTQIEETAITELRIFYNVDNADDEIITIERMKRPVTVNFATWQRKSEYS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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