Basic Information

Insect: Exephanes ischioxanthus
Gene Symbol: Hr39
Assembly: GCA_958510785.1
Location: OY294017.1:13042555-13048019[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.46 2.6e+03 -2.2 7.8 40 163 230 345 197 359 0.67

2 4 4 2.3e+04 -6.4 8.3 76 129 363 423 330 462 0.51

3 4 7.2e-08 0.00041 20.2 0.0 1 21 530 550 530 555 0.92

4 4 2.4e-72 1.4e-68 232.6 0.0 89 408 588 905 561 905 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.46	2.6e+03	-2.2	7.8	40	163	230	345	197	359	0.67
2	4	4	2.3e+04	-6.4	8.3	76	129	363	423	330	462	0.51
3	4	7.2e-08	0.00041	20.2	0.0	1	21	530	550	530	555	0.92
4	4	2.4e-72	1.4e-68	232.6	0.0	89	408	588	905	561	905	0.84

Sequence Information

Coding Sequence: ATGTCGGAGCAAAACGGGCCCACGGAGGGCCCGGGCTGGTGGCCTCCGGCGCAATCGTGGAAGTCATCCACcacctcgtcgtcgttgccgATTCCATCGTCCCGCACACTCGAGACGGGAAAGAACGTTTCCGTCACGACTATCAACGTACCACCGGCCCAGGAAATGCACGATGGTAAAAGCGTCTGCAAGTTTGTGGGCGGACAGAACGGCGTGACCGTATCGGTGGTCTCGAGTTGCGGCAGCGGTACCGGCAACGGAATGGGCACAGGACCCGGCGGAGGCGGAGGAGGTGGCGCGTCCTCCTCGTGTCCGGATTCGAGTTCGCTCGACGATCTCGGGGACAGTGACGGTGAAGTTAGCAAAATCGACTTTCGCGGTGTTAATCTGCGAACGAAGAAGAAGCGCGATGCCTCCGGCGGATCGGAGAACGAGTGCGGCGCCGTCGGCGCCGACAATCTCGAGCATCAGCAGCCCGAGAGACCGATGTCATGGGAGGGCGAGCTTTCCGATCAGGAAATGTCGTCGAACACGATCACCAATCAGGACCACGAGGAGACATCGATGGAGGGTGTCCAAGTGTGCGGTGCGAGTCCAGGACCTCAGGAGCAAAAGTTCCCGATAAAACCGGAGCCGGATTTTCGGTCGAGTCCAGGTCTCATGATCGGTTCGCACAGCGACGTGAACCTGACACTGTCGCACGCCCAGCCGCTtcagcagcaccagcagcacCAGCACCGCGGCATCGACTCTCTCGAGCAGACCCAGCAGAGTGACTTGCCGTTGCTCGTCGGCAAGCTCCTCGGCGGTTACAACAGTTCGACGCCGAACCACAGTCCGATACTGAATCCCCGACATCACCTCACGAAGCACGGTCACACGAGGTCTCAGGTGCCGTCGCCGGACTCGGCGATACACTCGGCCTACAGCGTATTCAGTTCGCCGACCCAGAGTCCTCACGCCGCTCGTCATTCCGCCCTCGGTCCCGGTAGTCCGGTGCCGTCCTCGTCTCTATCGCTCTCGCGTCACAGTTTCAACAACTCGACGTCCTCCCTGTCGCTGTCGTTGTCCCACTCTTTGTCCCGCAACAATTCCGACGCCTCGAGCAGCTGCTACAGCTACGGCTCGCTCAGTCCTCCGACGCATTCGCCGGTCCAGCAGCCGAGACACTCTCACGCCCAGcaccatcatcatcaccatcaGCAATTGCCGCAGGGCAGTCCGTTGCATCTGCCCTCGGCCTCGGTGAGCAACGCTCATCACTACTCGACACCGGGCTCGGAAATTTCCTCCGAGGGCCATCCGGAGGACCAGGAGGATTGCAAGATCCCATCGGCGCCCTCGGGAATATCGACGAGGCAGCAGCTAATTAACAGTCCTTGTCCGATATGCGGCGACAAGATCAGCGGCTTTCACTACGGTATATTCTCGTGCGAGTCCTGCAAGGGTTTCTTCAAGCGTACCGTGCAAAATCGAAAGAATTACGTCTGCCTGCGCGGCGCCGGCTGTCCGGTGACCGTCGCCACGAGAAAGAAATGCCCCGCTTGCCGCTTCGACAAGTGTCTCAACATGGGAATGAAACTTGAGGCGATTCGGGAGGACAGAACGCGTGGCGGCAGAAGCACCTATCAGTGCACTTACACCCTACCGGCGAATCTGATCGGCAGTTCCGCCGGTGGAATGCCCGGGGACAAGATGACCGGAGGCACGTGCAGTCCCGCCCCGCCGGGCTCCGAGCATCATCATTCCGCGAGACATCACTGGAATCACTCGCACAAGATGCAAGTCGTGCCCCAGTTGCTGCAGGACATAATGGACGTTGAGCATCTTTGGCActacaacgacaacgacagaACGTCGGCGGGCAGTCAGAGCTCCAGTCTCGGTGGAAACGGCGGCGGGATGACGAACGAAATACCCGGGGGTCTCGGTTCGAGTGCTGGCAGTGGAAGCGGTGCGAGTAGCAACGGCAATGTCGACAATCGTTGCGAACCGGCGAGATCGAGCCCGCCCGGAAACGCCGGCAACAACGAGCATCAGCAACAGCAGGCGAATTCACCGACGAACAACCAATCGAGCGGCGGCACAAACGCCACCAATCCCAATGGAAATTCGACTCAGAATCCCGACTTCCTGTCGAACCTTTGCAACATTGCCGATCACAGATTGTACAAGATCGTTAAGTGGTGCAAGAGTTTGCCACTcttcaaaaatatatcgatcgacgatcaGATATGCCTGTTGATTAATTCGTGGTGCGAACTCCTGCTGTTCTCGTGCTGCTTCAGGAGCATGAGCACTCCCGGGGAGATCAGAGTCTCACTCGGCAAATCCATCACCCTCGAGCAAGCGAGACAACTGGGACTGGCCACTTGCATCGAAAGGATGCTCGCGTTCACGAATAATCTCAGGAGGCTCAGGGTCGATCAGTACGAATACGTGGCGATGAAGGTGATCGTTCTGTTGACTTCGGACACGAGCGAATTGAAGGAACCCGAGAAAGTACGAGCATCGCAGGAAAAGGCTTTGCAGGCTCTACAGCAGTACACGATCGCCAAGTATCCGGAAATGCCGGCAAAATTCGGTGAGCTTCTCCTGCGGATACCGGACCTGCAGAGAACTTGCCAAGCCGGCAAGGAGTTGCTGAGTGCTAAGCGCGCCGAGGGCGAGGGCAGCTCTTTCAATCTATTGATGGAATTGCTTCGTGGAGATCACTGA
Protein Sequence: MSEQNGPTEGPGWWPPAQSWKSSTTSSSLPIPSSRTLETGKNVSVTTINVPPAQEMHDGKSVCKFVGGQNGVTVSVVSSCGSGTGNGMGTGPGGGGGGGASSSCPDSSSLDDLGDSDGEVSKIDFRGVNLRTKKKRDASGGSENECGAVGADNLEHQQPERPMSWEGELSDQEMSSNTITNQDHEETSMEGVQVCGASPGPQEQKFPIKPEPDFRSSPGLMIGSHSDVNLTLSHAQPLQQHQQHQHRGIDSLEQTQQSDLPLLVGKLLGGYNSSTPNHSPILNPRHHLTKHGHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGPGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHSHAQHHHHHHQQLPQGSPLHLPSASVSNAHHYSTPGSEISSEGHPEDQEDCKIPSAPSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLIGSSAGGMPGDKMTGGTCSPAPPGSEHHHSARHHWNHSHKMQVVPQLLQDIMDVEHLWHYNDNDRTSAGSQSSSLGGNGGGMTNEIPGGLGSSAGSGSGASSNGNVDNRCEPARSSPPGNAGNNEHQQQQANSPTNNQSSGGTNATNPNGNSTQNPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIAKYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00059522;
90% Identity: iTF_00057987;
80% Identity: iTF_00721289;