Epin022749.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Euzophera pinguis
Gene Symbol
-
Assembly
GCA_947363495.1
Location
OX376169.1:8476252-8489574[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 9.7e-05 0.0076 17.3 0.1 3 23 132 152 131 152 0.97
2 17 8.8e-07 6.9e-05 23.7 1.2 1 23 158 180 158 180 0.99
3 17 5.5e-06 0.00043 21.2 2.7 1 23 186 208 186 208 0.99
4 17 3.6e-06 0.00028 21.8 2.6 1 23 223 245 223 245 0.98
5 17 0.00022 0.017 16.2 0.7 1 23 260 282 260 282 0.98
6 17 5e-05 0.0039 18.2 3.1 1 23 297 319 297 319 0.98
7 17 3.4e-07 2.6e-05 25.0 1.4 1 23 334 356 334 356 0.99
8 17 1.1e-05 0.00086 20.2 2.1 1 23 362 384 362 384 0.99
9 17 0.035 2.8 9.2 1.8 1 23 391 413 391 413 0.98
10 17 5.9e-07 4.6e-05 24.2 2.3 1 23 419 441 419 441 0.99
11 17 0.041 3.2 9.0 1.8 1 23 448 470 448 470 0.98
12 17 2.4e-06 0.00019 22.3 1.5 1 23 476 498 476 498 0.99
13 17 0.00046 0.036 15.1 0.7 1 23 505 527 505 527 0.99
14 17 2.7e-06 0.00021 22.2 1.9 1 23 533 555 533 555 0.98
15 17 0.002 0.15 13.2 0.3 1 20 561 580 561 583 0.93
16 17 3.8e-05 0.003 18.6 1.4 2 23 590 611 589 611 0.96
17 17 3.4e-06 0.00027 21.8 1.4 1 23 617 640 617 640 0.97

Sequence Information

Coding Sequence
ATGTTCGAGCAGCAGATCAAAGCAGAGCCTATGAGCTTCTACTCCTCCCACGCTCACATCCACTCCGGCCCCCCAACAATAGTCCGATCAGACTCCAACCATGCCATCATAAACATGAACCAGCACCATGCACACCAAGAAGACTCCAAGGACAGTCTGATAGTACAACACCAAGTACAACACCAACAAGAGCTCATGGAACAGCACCAGCAACAAGAAATGCAACAACAGGATGATGAGTTAAGCTTTAAAGGAATTGACGATGAAGGGGTTGAAATGGATATGGATGGCAGGCAATGTTCTCAGGGTATGGGTGTCGACATGGGATCAGTTCAAACCAAAATGGAAGTGTCAAATGGAGGCGGCCAGGCAACTCGTTCAAAACCACAGGCTTGTAAAGTATGTGGCAAAGTACTGTCTTCTGCTTCCTCATATTACGTCCATATGAAGCTACATTCTGGAAACAAGCCCTTTCAGTGCACTGTTTGCGATgcagccttctgccgcaagccgtacctggaagtacacatgcgcacccatacaggcgaacgtccgttccaatgcgacctttgtctcaaacggttcacacagaagtctagccttaatacgcacaaacgcgtacatacagatgagcacatgcgggcgttgatggtgaaggaccggccctacaagtgcgaactctgtcagatgcggttcacgcagagttccagcctcaaccgccacaagaaaatacacacggACGACCACAAACGCGCCCTCCTAGCCAAGGACCGGCCTTTTCAATGCGGCGTCTGCTTTGTGAGATTCACCCAGAAATCGAGTTTGGGCCGGCATGGAAAAATACATACCGAGGAGCACAGACGAGCCCTGTTAGAGAAAGTgcggccgtaccagtgccacatctgttttatgcgcttcactcagaagtccagcctgggccgacatgggaaaatacacactgAGGAGCACATCCAATCGCTGATCAACAAAGTGCGCCCCTATCAGTGCGAGATCTGTGACAAGCGGTTCACTCAGAAGTCAAGCCTTGGCACTCATAAACGTATACACACTGgcgagcggccgtatcagtgcgacgcgtgtctgaagcgcttcacgcagaagtccagcctgaatatacataaacggacgcacacagtccaggggagaccgttccagtgcctgtcgtgcccggccgccttcacctgcaagcaatacctggagatacacacgcgcacccacaccggcgagcggccgtatcagtgcgacatctgcctgaagcgcttcacgcagaaatcaagcctcaacattcacaagcggacgcactcagtgcagggccggccgttccagtgcctgcagtgcccggctgccttcacctgcaagcaatacctagaaatacacaaccgcacgcacacgggcgagcggccctaccagtgtgacgtatgcctcaagagattcgcgcaaaaatcgacactcaatatacacaaaagaacgcacacagtgcaagggcggccgtatcaatgcatggagtgcccagcggcgttcacatgcaagccttacttggagatacacatgcgcacgcacacaggcgagcgcccgttcgagtgtgatgtctgttacaaacgcttcacgcagaaatcgacgctcaacatacacaagcgaatccataccgGTGAACGTCCATACGCTTGTGATATTTGCCAAAAACGATTTGCAGTGAAGAGCTATGTAACAGCGCACAGGTGGTCGCACGTGGCGGATAAGCCGCTGAACTGCGACCGGTGCTCGATGACGTTCACCAGCAAGTCGCAGTTCGCGCTGCACATCCGCACGCACTCCGCCGGCTCCTGCTACGAGTGCAGCGTCTGCGGACGAACATTCGTCAGGGACAGCTATCTTATAAGGCACCACAATCGTGTCCACCGCGAGAATCACAGCAACGTATCTGCTAACAGCATCGGCACCATCAACAGCGTGGCCACCAACACTAACAATTCCAACAGCAACTTCGACTCGCCCGGCGTCTGTGACTTAAGCTTCGTGCCCATGGTGAACCGGTATATGACGTCACAGGGCACGCAGGTGTCAATGCAAGACAGCAAAATGTCGGCGATGTCTCCGCAGTCTATAGCTTCTATATCTTCGCCCCCTCCCCCGCACACGCCCACCCCGCAGCCACAGATGTCTGGTCAAATGCATCTAGCAGACTGA
Protein Sequence
MFEQQIKAEPMSFYSSHAHIHSGPPTIVRSDSNHAIINMNQHHAHQEDSKDSLIVQHQVQHQQELMEQHQQQEMQQQDDELSFKGIDDEGVEMDMDGRQCSQGMGVDMGSVQTKMEVSNGGGQATRSKPQACKVCGKVLSSASSYYVHMKLHSGNKPFQCTVCDAAFCRKPYLEVHMRTHTGERPFQCDLCLKRFTQKSSLNTHKRVHTDEHMRALMVKDRPYKCELCQMRFTQSSSLNRHKKIHTDDHKRALLAKDRPFQCGVCFVRFTQKSSLGRHGKIHTEEHRRALLEKVRPYQCHICFMRFTQKSSLGRHGKIHTEEHIQSLINKVRPYQCEICDKRFTQKSSLGTHKRIHTGERPYQCDACLKRFTQKSSLNIHKRTHTVQGRPFQCLSCPAAFTCKQYLEIHTRTHTGERPYQCDICLKRFTQKSSLNIHKRTHSVQGRPFQCLQCPAAFTCKQYLEIHNRTHTGERPYQCDVCLKRFAQKSTLNIHKRTHTVQGRPYQCMECPAAFTCKPYLEIHMRTHTGERPFECDVCYKRFTQKSTLNIHKRIHTGERPYACDICQKRFAVKSYVTAHRWSHVADKPLNCDRCSMTFTSKSQFALHIRTHSAGSCYECSVCGRTFVRDSYLIRHHNRVHRENHSNVSANSIGTINSVATNTNNSNSNFDSPGVCDLSFVPMVNRYMTSQGTQVSMQDSKMSAMSPQSIASISSPPPPHTPTPQPQMSGQMHLAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01246112;
90% Identity
iTF_01076785;
80% Identity
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