Epin024533.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Euzophera pinguis
Gene Symbol
egg
Assembly
GCA_947363495.1
Location
OX376183.1:3067823-3124563[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 2.7 1.2e+04 -3.4 0.0 29 38 1625 1634 1599 1635 0.70
2 2 1.8e-14 8.2e-11 42.0 0.0 4 75 1666 1730 1663 1732 0.89

Sequence Information

Coding Sequence
ATGAGTTCCGACCACCAGGAACTAATCGCAGTAAAAGATGATGAGAAATTCAAGTCTCCCCAACCATCCGATACAGTAGTAAAATCAAAAGACAGCCCTGATTCAACACCAAGAGATTGTGGAGATATTAACAATCAAAAACTAGACAATTTGATCATCAAACCTGTTGAATCGAATAAAACATCAGAATTTGATGAAGAAGATGATTTTAACAGTGACGAGCTGCAGTTGAGATGGGATGAGGATGATGAGTCAAATATTGATGGAACACCAACTACTACTAGTAATAGTAATGTGAAAGAATCAGAGAGTCATAATGAAGATAATGTAGTGTCAAATGAAACAGGAACTATAGAAAACCCAGAAACATTGTTGGTTACAGCAGTGGTAGAATTAGAAAATGCTTTGAAAAATACCAATGATGAAGATGTTGTTCTTCTCGGTTCAGATCATTTGAAAAGTGCTATTGATGCTGAACATGATCAAAGTGTAAAGGATGCGGCCAATTCTTCCAAGGAAATTCTACAAAATATTGATGAATTTATTGGCAAGGACACAGATGTAGTTGAAGTATCCAATAATTCAGATGAAAATCTTGAAAATAAAGTACCAATTGATTCTGAACATAATATCATTGATTCTAAGCTCATCTCTGAGTCTAATTTAGATCCTAATAATAAAAGTCAAGATCCAGAAGGTAAAGTTGATTCAAACACAACTAAAATGGATGTAGATACTCCAATTATTTTGTCAAAAGATGTCAGCAATGTTGATGGTGTAACGGAACATAAAAAACCCACACATAGAATTAATCTGGATGAAAGCTTCAATAATCTTGACAAAAGTAATATTCTTTCAAGCACTATGAATGAATCTTTTGTAGACAGCGACGTCAAATTCGAACATGGGTTGAAACGACCAGACATGATGTTGGAAATACCAACTCAAGAAATAATCGACTGTTTGGATGATTTTGATGACTCAGATTGTGAAAATAATAAAGAGGACACAGAGCAGAGTGTGGATATTAGTAAACAAATTGATAGTCTAAAGGAAGATGTTGATCCGAAAAAGCTGGACAATGAAAATGATATTATTGATCAACATATAATAGGAAATGTCCCAGAAATAGTCAAAACAGATAGAGTCAAGTCTGCTGATGTCAATGCGGTAAATTTAGATGAAAAGGAAGATTCCGAAAATGATGTGGAAATGGCAGAAGTTTCCCTAAAAGAAGCTAGTGCGAAAGAAAATCCAGAAATTCTTGAGAAAGAAAAATGTCCAGTATCAAGTAAACCTGTTAAAATTTCATGTGTCAGTGATGAACATAAAACCTTATCTGAAGAAGACAATGCGATGGAAGTGGATGAAATTAAAACAATCGAAGAAAAACTAGCTCCTGGACAAAATGTGACTTCTGATTTGTATAAACCTTCCGAAACAACTATTTCAAATGTAGAATTAAAATCAAAAATTGTATCGAATAAGATTGAATGTGAATCTTCAATAACTAAATTCGTAGAAGAAGATTCAAATAAAGATATTAAAATGATTGATGTAAAGAAAACTGAACAAATCAAGATACAAGATACTTGTGGTAACTCTGAACAAATTGTGTCAGAAGTGACCAAAACTGTAGAACTGATTGAAACAAAATCTACTGAACAGCATTCAGATAAAACACAGAATGAAAATTTATCAAGTGATTTAAAGACACCAATAATTGAAGTTGCGGTAAATATTGATTTACCCATTGACCAAAAATCGCAAAATGTAGACCCAAATGACACTCAAATTTCAAGTGTAGATCAAATAGTCCCATCAAATAAAACACAAATTGTTGACAAAGAGATAGATTCAGAACACAGAACGGTATCAAAAAAATCTGAAAATATAGAAGTAGAAGTTGCACATATAGATAAAAATAAAGAATCAGACAACCAATTAGAAACTGATACAGAACAATCAGTTCAAGTTTTAAAATTATCAGAAGAATTAACATCAACTTCAATAATAGATAATAAATCTGACACAGACATGCAGCCAAGCAATACAGCGCAAAATACTGGACCAACATCACAAATATTGGAGCCAAAAGCAGATGAAGAACAACCACCAAATAAGTCTGAAGACAAACCAATCGACCAAGTGTCTCAAACTGAATCACCAAATACTGAACCAACAACACCAATATTGGAGCCAAAAGCAAATGCAGATCAAAAATCAAAGGCATCTGAAGACACAATGCAAATCGACCAACCAATATTAGATCAATTTGATACAAACAAAACTGAATCGCCAAATACTGAACCAACAACACCATTATTGGAACTAAAAGTAGATACAGAAAAGCCATCAACATCTGATCAAACATTGGATCAAATTCCCTATACGACAGATGAAGTACCAGAGGTAGAAGATAGTTTGGGATTGTTGGCCGAATCTTCAAGGGTAGTGGAAGATGATGAAGAAGTCGAGGATGATGAGGAAGCTGATGCCGATGATGATGAAGACTTTGACCAGGATGATGAAAGCAGCAACCAAATGACAGCGGAACATTCAGAAGACTCGAGCGCTCAGCCCGACAAGGAAGATGGACAGACAGACAAGGAGGACGACCTTGAAAAAGATATAAATGTAGATAAAGATGAACAACTCTCTTCCAAAGAGTTTGGTGCTATTGTCAGTGTCACTACAGATGCCGATATGGAAATAACCGCGGAAGAAAGTAAGATCGCCGACGACGTAACAGTATCTAAAGATATCAGGCCCTCAGAACTGGATGCTGCCGAGACTAAAGTGGATAAATTGACTCCGTCAGAACAGTCAATAGACATAGAGACAGTCAAACTGTCGGACACATCGGATAACGAGACCGACACAGACCAATACAAACCTAACAGTATATTGAAGAGGCTGTTAGACAAACAAGGTGGGTTTCAAGCCGTTCTGCCTCCGGACATGTTAAAGGTTGCCGGTGTTTCAGAAGGCGTAGTGGATGTGGAAGGCAGCTCGTCTGAAGATGATGTCCAAGAGATAAACAAAAAGTCAGTTGACCAAGAGGCGACATCTGTCGTCCAAAAGGAAAAAACGAAACCGCAAGAAGTAATAAGCAAGCCGACAACTCCTGAGAAAGATGATGCTGCAAAAAAAGAAGAGGATCAGGTAAAGGCAGATTCTGAAGTATTAAATTTGGATTCAGACGACGATGTTGTGCCAACGATAACTGACGGCGCACCGCTAGGCAAGCCCGAATCGAACAAGTGTATAAACCCTTGTTGTCCGAGCGGCGCTCGCGCTACTTACGTAATGGCTGATGTGTCCGCTCGCGCGTACTACGACGCGGACAAGCGTAAGCGGTACCGAGTGTGCGTGCCATGTGCCGAGAACGCCGCTAGGAGGACTGAGGGCCTCGTGACAGGAATCAAGGAGCTGACCCCACTCCTCCAGTTGGATCTTCGCAAGGTGTCTTCGGAAACTGTTGAGATCTCAGACTCGGACTCTGACGATGGTGGGGAAGACGAAAAACCCGAAGTTCTTGGCGATGGAGGCGTGAAATTTTTGGAAGAACATTTGTCCGACGTAATCAACGAGACGTGGCTCAAGTACAAGTTGGACGAGAGGCTTACTGACGCCCAGAGCGAGCTGAACAATGAATTGGAGAAATTGGAAGCGGAAAGCAAAGAGATCGACAGCATGCTGAACGAGTGCCAAGTAGCCACGGATCTCCTACGGAACCAGTTGTACGCGACTTTTGAACCCGAGAGGCGGGAATTGGCCTCCATTTGTATTGTAGACACGCCTGTTGAAAAGAAGAGTTTGAAACGTCGAACTTCGGCCCCAAGCGAACAATCCGCCAAACGGGCCGCCATACCACTGGGGTATACGCCTCTCGATGTTGACAAAGACGTCTCAGTAGTGAAGTTGTCTGCCGAAGCCGCGCCTTTAGATCTACCGCCGCCAGGGGAGATAATCCGGGCCCCGCTTCGCATCGGCTTGCCTGTTTTCGCTATGAGAAATTCCTTCTGCACCTGGGTACCTGGAAGAATCATAGACGTACACCCTAAGAATCCAGCGAACCCGTTCACGATGTGCCGAGTCCGATTTGAAATTCGAACTAAAATCGCGACTCGCGTTCTAGCGGGCCGCTGCCTCGCGTACTTGGAGCCTGCTGACGTCAGACTGACTATCGGCACTCGCGTCATAGCGTTATCAAAAGAGAACGCAAAAAGAGAGGAAGTAGATAAGGGCAAGAAGAGCTTCTACTCCGGCATAGTAGCAGAGATACCAAACCCAGTCAACAATTACAGATATCTAGTATTCTTCGACCACGGCTACGCGCAATACGTCCAACATCGCGACACTCGCGTAGTCTGCGAGAGTTCCACCCTAGTTTGGGAAGAAGTTCATCCGAACTCCAGAGAATTCGTGAAACAATACCTTCTAGCGTACCCCGAGAGGCCCATGGTGCGACTGCATGCTGGACAGAGCCTCAAGACCGAGTGGAACGGAAAATGGTGGGTAACGAAGGTTTTACAAGTGGACGCGTCGCTAGTGGAAGTGTCCTTCGAAGACAACCGCACGGAGTGGATATACCGGGGCTCCACCAGGCTGGCACCCTTGTTCCTGGAACTGCAGGCAGCAGAGAGACAGAGGGCCAGGCCTTTGCCCAGGAGCAATCAGAGGAGGATGAACATGCCATACGTAGAGTATACTCGTTCAGAGGAACAGAACAAAGCTGAAGCCTTAGCGTTGGAACAAGCAAAACAACAACAACATAATGAGGAGATGCGTCGCCAACGTGCCGTGGCTAAGAAATCGACCGCCTTACCAGTTCCAGCGAATCAAACCGCACATTCTAATCTCGACAGCGTCACCAGCAGAGTCGTGTATTACACGCCCAAAAATGCGGTGAAACCGCACAAGATGTCGCCGCACACTTGTTCGGCGAAGTGCAAACGTGCCGACGTGCTGTCTCTGAAGGAATTGCGGACCTACAACCCGCTGGCCAAACCCTTGCTGAGCGGCTGGGAGAGACAAATAGTCCGTTACAAAGGACACAAAGAAGTAATGTACCGCGCACCGTGCGGTAGAAGATTAAGAAACATGCGGGAACTGCACAAGTACTTGCAGGCTGTTCAGTCGGACATGGCGGTAGATCTGTTCGACTTCAGCGCGAACACGCACTGCCTCGCCGAGTTTGTGCTGAACAAGTGTCTCGTCGGCAAGAAGGACCTCTCTCATGGCAAAGAGAACGTGCCGGTCCCATGCGTGAACTACTACGACGAGTCTCTACCAGAGTTTTGTTCGTACAACACCGAGCGTACGCCCACTGCTGGGGTACCGCTTAACCTTGACCCGGAGTTCTTGTGCGGCTGCGACTGTACTGATGATTGTGAGGACAAATCGAAATGCGCCTGCTGGAAGATGACGCTAGAGGGCGCTCGCACAATCGGCCTTCAAGGGACCAACGTTGGCTACGAGCACAAGAGGCTGCCAGACCCGCTGCCTTCCGGGATATACGAGTGTAAATGTAAGCAGACGTGTCTAAACAGAGTGGCGCAACATCCATTGCAGCTAAAGTTACAAGTGTTCAAGACGATGAACCGTGGTTGGGGCATCCGAGCTTTGAACGACGTGCCTAAAGGATCATTCCTTTGTGTATATGCCGGGAATTTATTGACGGACGCTACGGCTAACTTGGACGGTCTAAACGAAGGCGACGAATATTTAGCTGAGTTGGACTACATAGAAGTAGTGGAACAGATGAAGGAAGGATACGAGGAGGATATTCCTGACGAAGACAAGAAACTCGACCGGAGATCGTCAAAATCATCTGAAGAAGAATCGGCATCCGAGGAAGAAGATACTGAGCCCAAAGATGATCAAGACGACGACTTTCAACCGGGGTACATCGGCATGGGGCTCACTGAATTCAGTAAGCGTCTGAGGAAAAGAGACAGGACGAGGAAGAAAGACGCAGAGAAAGAGAAAGGGAAAGAGATAGATAAGGGAATGGAGGACGATGGCTGCATCACTATTAGTGATGACGAAGAAGCAAAAGAGCCGACACGGTTTATGGCGCAAGCTGGCATCGGCGGGAAGGAATTTGTATCTAAATATAGttctgttcgtacactattcggcaaggacgaggcgtgttacatcatggacgctaaagttcagggcaacattggaaggtatctcaatTTATATACCCAATGGCGAGCCAAGAACGGTAAAAGTAGAGAATGGAACAAGTGGCGAAAAAAATTAGAGGATAGAACGAGTTGCGAACGGGACAAGCTGCGAGTGGGACGGACTGCGGGTGGGACGGGTTGCGATTTGGACGAGTTGCGAATGGGACGACCTGCTTCCGACCCGTTATGCAACGGGTCTTGCAACAAGCGCGCGGGCGGGGCTATAGCGGTACCGCGCGTGCGACAAAATGCTCAAATATTGAGTATTTTACGATTGTTTAATACCATGTTGAAAAAGCATCATTAG
Protein Sequence
MSSDHQELIAVKDDEKFKSPQPSDTVVKSKDSPDSTPRDCGDINNQKLDNLIIKPVESNKTSEFDEEDDFNSDELQLRWDEDDESNIDGTPTTTSNSNVKESESHNEDNVVSNETGTIENPETLLVTAVVELENALKNTNDEDVVLLGSDHLKSAIDAEHDQSVKDAANSSKEILQNIDEFIGKDTDVVEVSNNSDENLENKVPIDSEHNIIDSKLISESNLDPNNKSQDPEGKVDSNTTKMDVDTPIILSKDVSNVDGVTEHKKPTHRINLDESFNNLDKSNILSSTMNESFVDSDVKFEHGLKRPDMMLEIPTQEIIDCLDDFDDSDCENNKEDTEQSVDISKQIDSLKEDVDPKKLDNENDIIDQHIIGNVPEIVKTDRVKSADVNAVNLDEKEDSENDVEMAEVSLKEASAKENPEILEKEKCPVSSKPVKISCVSDEHKTLSEEDNAMEVDEIKTIEEKLAPGQNVTSDLYKPSETTISNVELKSKIVSNKIECESSITKFVEEDSNKDIKMIDVKKTEQIKIQDTCGNSEQIVSEVTKTVELIETKSTEQHSDKTQNENLSSDLKTPIIEVAVNIDLPIDQKSQNVDPNDTQISSVDQIVPSNKTQIVDKEIDSEHRTVSKKSENIEVEVAHIDKNKESDNQLETDTEQSVQVLKLSEELTSTSIIDNKSDTDMQPSNTAQNTGPTSQILEPKADEEQPPNKSEDKPIDQVSQTESPNTEPTTPILEPKANADQKSKASEDTMQIDQPILDQFDTNKTESPNTEPTTPLLELKVDTEKPSTSDQTLDQIPYTTDEVPEVEDSLGLLAESSRVVEDDEEVEDDEEADADDDEDFDQDDESSNQMTAEHSEDSSAQPDKEDGQTDKEDDLEKDINVDKDEQLSSKEFGAIVSVTTDADMEITAEESKIADDVTVSKDIRPSELDAAETKVDKLTPSEQSIDIETVKLSDTSDNETDTDQYKPNSILKRLLDKQGGFQAVLPPDMLKVAGVSEGVVDVEGSSSEDDVQEINKKSVDQEATSVVQKEKTKPQEVISKPTTPEKDDAAKKEEDQVKADSEVLNLDSDDDVVPTITDGAPLGKPESNKCINPCCPSGARATYVMADVSARAYYDADKRKRYRVCVPCAENAARRTEGLVTGIKELTPLLQLDLRKVSSETVEISDSDSDDGGEDEKPEVLGDGGVKFLEEHLSDVINETWLKYKLDERLTDAQSELNNELEKLEAESKEIDSMLNECQVATDLLRNQLYATFEPERRELASICIVDTPVEKKSLKRRTSAPSEQSAKRAAIPLGYTPLDVDKDVSVVKLSAEAAPLDLPPPGEIIRAPLRIGLPVFAMRNSFCTWVPGRIIDVHPKNPANPFTMCRVRFEIRTKIATRVLAGRCLAYLEPADVRLTIGTRVIALSKENAKREEVDKGKKSFYSGIVAEIPNPVNNYRYLVFFDHGYAQYVQHRDTRVVCESSTLVWEEVHPNSREFVKQYLLAYPERPMVRLHAGQSLKTEWNGKWWVTKVLQVDASLVEVSFEDNRTEWIYRGSTRLAPLFLELQAAERQRARPLPRSNQRRMNMPYVEYTRSEEQNKAEALALEQAKQQQHNEEMRRQRAVAKKSTALPVPANQTAHSNLDSVTSRVVYYTPKNAVKPHKMSPHTCSAKCKRADVLSLKELRTYNPLAKPLLSGWERQIVRYKGHKEVMYRAPCGRRLRNMRELHKYLQAVQSDMAVDLFDFSANTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDESLPEFCSYNTERTPTAGVPLNLDPEFLCGCDCTDDCEDKSKCACWKMTLEGARTIGLQGTNVGYEHKRLPDPLPSGIYECKCKQTCLNRVAQHPLQLKLQVFKTMNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPDEDKKLDRRSSKSSEEESASEEEDTEPKDDQDDDFQPGYIGMGLTEFSKRLRKRDRTRKKDAEKEKGKEIDKGMEDDGCITISDDEEAKEPTRFMAQAGIGGKEFVSKYSSVRTLFGKDEACYIMDAKVQGNIGRYLNLYTQWRAKNGKSREWNKWRKKLEDRTSCERDKLRVGRTAGGTGCDLDELRMGRPASDPLCNGSCNKRAGGAIAVPRVRQNAQILSILRLFNTMLKKHH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-