Basic Information

Gene Symbol
Aef1
Assembly
GCA_963920795.1
Location
OY987204.1:17276635-17277045[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.021 1.7e+02 3.6 0.2 22 46 9 33 5 36 0.88
2 4 8e-06 0.065 14.5 0.1 21 51 36 66 33 67 0.88
3 4 0.0025 21 6.5 0.0 21 51 64 94 62 95 0.87
4 4 8.2e-05 0.67 11.3 0.1 21 47 92 118 90 123 0.89

Sequence Information

Coding Sequence
ATGACTGTAGCCAACGGCCCCGTAGACAAGCCTTTTCAATGCAACGTGTGTGAAAGGCGATTTCGTCAGCTAAGCACATTGACGAACCATGTGAAAATCCACACTGGCGAAAAACCCTATAAATGTACAATATGCGAGAAGCACTTCCGGCAATCCAGCACCCTAACGAATCATCTGAAAATACATACTGGTGAAAAACCTTTCAACTGCACCTACTGTGGCAAGCAATTTCGTCAGTTGAGCACACTCACGAATCATCTTAAGATCCACACGGGGGAAAAGCCATTCGAGTGTGCCGTATGCAAGAAACAATTTCGGCAGTCGAGCACACTGAACAATCACATAAAAATCCACGTTATGGACAAACTCTACATACCTTTCGAAATAAAGGCTGAAGAAGAGGAGGGCTGA
Protein Sequence
MTVANGPVDKPFQCNVCERRFRQLSTLTNHVKIHTGEKPYKCTICEKHFRQSSTLTNHLKIHTGEKPFNCTYCGKQFRQLSTLTNHLKIHTGEKPFECAVCKKQFRQSSTLNNHIKIHVMDKLYIPFEIKAEEEEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00203877;
90% Identity
iTF_01540912;
80% Identity
iTF_01461411;