Basic Information

Insect: Eutolmus rufibarbis
Gene Symbol: ftz-f1
Assembly: GCA_963920795.1
Location: OY987204.1:48227878-48249681[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 1.8e-19 1.8e-15 58.4 0.8 1 86 16 101 16 137 0.60

2 2 6.6e-72 6.7e-68 231.1 1.3 150 408 176 421 150 423 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	1.8e-19	1.8e-15	58.4	0.8	1	86	16	101	16	137	0.60
2	2	6.6e-72	6.7e-68	231.1	1.3	150	408	176	421	150	423	0.90

Sequence Information

Coding Sequence: ATGAGATCGTGTGACGAACTGCGACGGCGCGAACTTGTTGCGGCAGCTGTGAGAGCCGATCGCATGCGCGGTGGACGGAATAAGTTTGGACCAATGTACAAAAGGGATAGGGCgcgaaaattacaaatgatGAGGCAGAGGCAATTAGCTCTTCAAGCGATAAGAGGCTCAATGGGCTCGACGGAGATCAAGCCAGGACAACTGTCGCCGACCGCGGGGTACCAGCAGACCTACCCGAGTATGAACATAAAGCAAGAAATCCAAATTCCACAGGTGTCGTCGTTAACACAGTCTCCAGATTCATCACCGAGTCCCATGGCCATTGCCCTCGGCCAAGTGAATCCCAACGCGGCGGCCATCGCGACCTCCCTGAGCGGAAACAGTGGCGGCGGAACGAACACGACGACGGTGACCGGGGCCGGCGGCGGAGCGGGCGGCGGAGGCTGCCCCCAGGGATCGGGTTCGGGAACGTCGCTGCAAGAAACATCAGATTCCAAATTGTGCTTCGACACGGGTACCAATCCTTCGAGTACTGCGGACTCAGTCAGTAGTGAACCACTTAGAGTATCTCCTATGATAAGGGAATTTGTCCAGTCGATCGACGACAGAGAGTGGCAGGCTCAACTATTCACATTACTCCAAAAACAGTCGTACAACCAGTGCGAGGTGGATCTCTTCGAGTTGATGTGCAAAGTGCTTGACCAAAACTTATTTTCGCAAGTTGACTGGGCGCGAAATACTGTGTTCTTTAAAGATCTCAAGGTGGACGATCAAATGAAGCTGCTTCAACATTCTTGGTCAGATATGCTTGTGCTGGACCACCTGCATCAGAGATTGCACAACAATCTGCCTGATGAGACCCCACTTCACAACGGGCAAATTTTCAATCTGCTGGACCTGGGCCTTCTGGGCGTACCCCAGCTCGcggattattttaatgagCTCCAAAACAAGCTGCAGGAATTGAAGTTCGATATGGGCGACTACGTTTGTATGAAATTCCTAATCCTACTTAATCCAAATGTACGAGGAATCATAAACAAGAAAACCGTCCTGGAGGGACACGAAAATGTTCAAGCAGCCCTCCTGGATTACACCTTGACCTGCTATCCTTCAGTGACGgATAAATTTAGTCGACTGCTGAGCATACTGCCTGAAATCCATGCCATGGCAGCCCGAGGAGAGGAGCACTTATACCTGAAACACTGCGCGGGAAGTGCCCCTACACAGACCCTCCTCATGGAAATGTTACACGCGAAGCGGAAGGTGTAA
Protein Sequence: MRSCDELRRRELVAAAVRADRMRGGRNKFGPMYKRDRARKLQMMRQRQLALQAIRGSMGSTEIKPGQLSPTAGYQQTYPSMNIKQEIQIPQVSSLTQSPDSSPSPMAIALGQVNPNAAAIATSLSGNSGGGTNTTTVTGAGGGAGGGGCPQGSGSGTSLQETSDSKLCFDTGTNPSSTADSVSSEPLRVSPMIREFVQSIDDREWQAQLFTLLQKQSYNQCEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHQRLHNNLPDETPLHNGQIFNLLDLGLLGVPQLADYFNELQNKLQELKFDMGDYVCMKFLILLNPNVRGIINKKTVLEGHENVQAALLDYTLTCYPSVTDKFSRLLSILPEIHAMAARGEEHLYLKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01431946;
90% Identity: iTF_00937379;
80% Identity: iTF_00717878;