Ehis031364.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eustalomyia histrio
Gene Symbol
ZFY
Assembly
GCA_949748255.1
Location
OX456525.1:141534537-141544020[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00012 0.012 17.4 3.1 3 23 207 227 206 227 0.97
2 12 6.5e-06 0.00068 21.4 2.1 1 23 233 256 233 256 0.97
3 12 0.00049 0.052 15.5 0.8 1 23 269 291 269 291 0.95
4 12 6.2e-05 0.0065 18.3 0.8 1 23 296 319 296 319 0.98
5 12 2.5e-06 0.00026 22.7 2.7 1 23 325 347 325 347 0.98
6 12 2.1e-06 0.00022 22.9 1.0 1 23 353 375 353 375 0.98
7 12 0.083 8.7 8.5 0.8 1 23 381 403 381 403 0.94
8 12 0.00048 0.051 15.5 0.4 2 23 409 430 408 430 0.97
9 12 0.00011 0.012 17.5 1.6 1 23 436 458 436 458 0.95
10 12 0.00043 0.045 15.6 5.1 1 23 464 486 464 486 0.98
11 12 3.2e-06 0.00033 22.4 1.0 1 23 492 514 492 514 0.98
12 12 5.8e-05 0.0061 18.4 0.5 1 23 520 542 520 542 0.97

Sequence Information

Coding Sequence
atgtTATTGGGTCGTATATGTCGAACCTGTTTAGAAAAATCTTCAGAAATGCATAAACTACGGGAATTTATTGAAGATGATTTACAAATCGAAGATATGCTTAATCAAGCTATACCCGACTTTGATCTGGAACTTGAGGAAACACCACTACCAGTAGAAATATGTAAAGAGTGCTTGGACAAGTTACGTGTATCATACAATTTCCACAACAAGTgtatggaaacaaataaacaactaaGAGAGATGTTGACTAAACATGCAAATGAAGAGGAGGATGAGGTGCCAGCTGAACTAAATGATATCCTACGGGAAGACGATATTTTAATGGATAATCTCAAAAAAGAACCTTTAGATGAAGGTTCAAATGGTAGCAATAATTTTCCTAATGCTCCAATGACAGAGTTTGCCGATGTTTTAAGTCCAAGTTTCCAAATGGATCCCGTAAAGGTTGAAACTGCTTTGGATGATGAAGAAAAGATGGCTGCTGATAGTGACGATGGCAATAGTTCGGATGATTATTGGCCTAACGATGATAAGGAGGATAGTGAAAGcaatttattCGAAACTGCCGATATTAAATCTAagagaaaatattgtaaaaaagccATTACTAAAATTTGTACTCAGTGCAATAGATCATATACGAATAATTTCCATTTCGCACGACACATGTCGGTACATTCATTGGAAAACGAATTTGTGTGCAATATATGTCAATACCGTTATAGCAGTGATTCAGAATTGAAAAGACacatgaaaagaaaacatactgTTAGTAAAACTAATAATATTGCTGATGAACCACATCCCTGTCCCGATTGCCCCatgatatttaaacataaaaattcattGGCAGGGCATAGAGTAATGCATATGGAAAGAGattttaaatgtgaaatttgTGGTGCTACTTGTAAAGTAATGGCAGCGCTAACCAGACATATGAATAGTAAACATCCTGATGTTTTGCCATACAAATGTCACAAATGTGATAAGGCTTTTGCAGTAGAATCACATTTAAAAGATCATATCAATGAGCATTTGGGACAGAAAAGACATAAGTGTCAAATGTGTGAAAAAAGTTTTGCTACCCCTGGCTTCTTAGAGGATCACATACGTACGCATACTGGAGAAACACCATTTTTATGTTTCCACTGCGGTGCAGGATTTAAAGCGTTAAATGTTTTGCGACAGCATTTACAATTacatggtgaaaaaaaaattcaatgtccTCAATGTCCTatgaaattttatgcccaaGGCTTTTTAACAAAGCATTTGAAGTCACATGCACCAGTTAAACTTCATGCTTGTGATATATGTGATGCGACTTTTACCCGAAAGGGTTCTTTGAATgaacataaatttaaacataCAGGACTAAGACCTTTCAAATGTGAAGAATGCAATTTAAGttttgtttttaaacgccattttaaaaaacataaacttgTTCATACCGGCGAAAAGCCTCACCAGTGCAATTATTGTGAACGTGCTTATGCTTCGAGTGGAGATTTGGTAAAACATTTACGTACTCATTTGGgtgaaaaaacctatttttgtaACGAATGCCCGgaagcttttaaatatttaaaagatttaaatgccCATAGAAATCAACATTACAGAGATAATTTGGCATTACAACAAAATCAAGAGGATAATGTTGCAAATATGTAA
Protein Sequence
MLLGRICRTCLEKSSEMHKLREFIEDDLQIEDMLNQAIPDFDLELEETPLPVEICKECLDKLRVSYNFHNKCMETNKQLREMLTKHANEEEDEVPAELNDILREDDILMDNLKKEPLDEGSNGSNNFPNAPMTEFADVLSPSFQMDPVKVETALDDEEKMAADSDDGNSSDDYWPNDDKEDSESNLFETADIKSKRKYCKKAITKICTQCNRSYTNNFHFARHMSVHSLENEFVCNICQYRYSSDSELKRHMKRKHTVSKTNNIADEPHPCPDCPMIFKHKNSLAGHRVMHMERDFKCEICGATCKVMAALTRHMNSKHPDVLPYKCHKCDKAFAVESHLKDHINEHLGQKRHKCQMCEKSFATPGFLEDHIRTHTGETPFLCFHCGAGFKALNVLRQHLQLHGEKKIQCPQCPMKFYAQGFLTKHLKSHAPVKLHACDICDATFTRKGSLNEHKFKHTGLRPFKCEECNLSFVFKRHFKKHKLVHTGEKPHQCNYCERAYASSGDLVKHLRTHLGEKTYFCNECPEAFKYLKDLNAHRNQHYRDNLALQQNQEDNVANM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00892989;
90% Identity
-
80% Identity
-