Ehis031366.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Eustalomyia histrio
Gene Symbol
ZNF275_1
Assembly
GCA_949748255.1
Location
OX456525.1:141554875-141558845[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 6.4e-05 0.0068 18.2 0.2 1 23 185 207 185 207 0.95
2 15 0.0012 0.13 14.2 0.3 1 23 213 235 213 235 0.99
3 15 7.8e-06 0.00082 21.1 0.4 1 23 280 302 280 302 0.98
4 15 1e-05 0.0011 20.8 0.3 1 23 423 445 423 445 0.96
5 15 0.05 5.2 9.1 0.5 1 23 451 473 451 473 0.95
6 15 5.9e-06 0.00062 21.5 0.3 1 23 490 512 490 512 0.98
7 15 0.021 2.2 10.3 0.3 1 23 521 544 521 544 0.95
8 15 0.0033 0.35 12.9 4.8 1 23 550 572 550 572 0.98
9 15 0.00026 0.027 16.3 0.4 2 23 579 600 578 600 0.97
10 15 3.2e-08 3.4e-06 28.6 0.7 1 23 606 628 606 628 0.96
11 15 0.0022 0.23 13.4 2.1 1 23 634 656 634 656 0.99
12 15 5.8e-05 0.0061 18.4 1.6 1 23 662 684 662 684 0.96
13 15 4.9e-05 0.0051 18.6 3.2 1 23 690 712 690 712 0.99
14 15 3.1e-06 0.00033 22.4 0.7 1 23 718 740 718 740 0.99
15 15 8.1e-05 0.0085 17.9 0.3 1 23 746 768 746 768 0.97

Sequence Information

Coding Sequence
ATGTCCGGTGATTTAAGCAAAAAGTGTCGTACCTGCTTATGCGATTCCCATATATTCCACCAACTGGATGATTATTTGGaaggaaattataaaattttggaaatgttGGATGAAATAGTGccgcaaatatttataaagaacacCTCGAATTTTTCCACATTGGTGTGTCAATCTTGTGTTGATAAATTGGAAACCAGttataaatttcaacaattgTGTATTGTAACCAACAATCGTCTACATGATTTAATGGGCATAGAAACTGCCGAACCGAAATTGGAGAAGTTGCTTGATCCTCTGACGGGAGATGatagttttaaaatgaaacaagaAATTATGGATGATGCTTGCTTTGAATGTGAAATTAATCCTGAAGATTTAGAGGAAGTGATGAAATCAGATAATGATTGGGGACCGTTCCAAGATAATGATTATGATACAGATTctagcaatgaaaaattatcagttttaaaagaaagaaaaaccaaaaaaactcctttaaaaattgaagaaattgaaaagcccaataaaaaaaatcgtcgtAAAGGACATTTTCCTTGTACTGAATGTGGTAAAGTATTTGATCGTATATATCGTCTAAAACGTCATGGAGCTGTACACACAAAATTGCGTCCTTATCGttgtgaaatttgtaaatatagttATGCAGCCGAAAAAACTTATAATGCTCATATATTAACTCatgaaaatggaaaagttaTTAATAAGGTGGAGGAGCTAGAGGACGATGACAAAAATGAAAGTAAAGAACTCAATGTTAGTATTAAAACTAATGAGAGTAAAGAAGAAAATGATACTGCTAAGGAATCGCAGACATTTCAATGTCCTGACTGTCCTaaatattttgagaaaaaagcTTCTTTATCGGCTCACTATAAAGTTCATACGAAAAAACCtaaaagtatttcaaataaacaatttaaaaatgaaattagtttaGAAATGGAAAAATTGGCAGAAAATTTAGAGAATAACAAGGAAATGGAAGTTTCAGATATGGAGGATGTACCCAAGGTTATTGTAAAAGAGGAAATAGAAGTGACACCACAAATCTATGAAGAACCTATGAACGATTTTGATGACAATATGGAATGGTTTAATAATGATTATGATGATTCCGAtgatgactcggaaaaaaatgtatttgataaACCCGGAGCTAAACAGCCTAAAAATATCGATTTTGTGGACACAGGCATAGGAGAAATAGAAAAaCCCAACAGCAGTAATAAAAGAAATGGTACTTTTCCTTGCGAAGTATGTGGTAAAGTTTTCGATCGTCCTTATCGTTTAAAACGCCATAGTTCCGTACATTCCCTGGCTAGACCACATGAatgtgaaatttgtaaatatcgtTTTGCCACCATCAATATTTTAAAGGCCCATTTGATACAACACGAAGGTGATGGCACTGGTAACTTGGCTTCCCAATCAAGGCCAGAAGGTTTCAAGTGTCCAGACTGTCCAAGACGTTTTGAAAAGCAAGCTTCTTTGTCGGCTCATCGTCAAATACATACCCGCAATGCAACAGAAGCTAATTATCCCTGTATGGTTTGTCAACGTCCCTTCATGTCGGTTAGATCTTTAACCGAACACATTACCAATAAACATCCCGAAGTAGAAAAACACAAATGCGATCAATGTGAAAAAACCTTCGTACTACATGCTCATCTGGTGGAACATTTAAATAGGCACAAAGGCAatagaaatttggtatgctTAATATGTGAAAAAGAATTTGGTTATACGAATACTTTGAAGGAACATATGCGTACGCATAGTGGTGAAAGTCCATATTTATGTCCTCAATGTGGTAAAACATTTCGTAGTGCTAGTAATTTACGCCAACATATGGAACGACATACGGGATTAAAGAAATATCAATGTCCGGAATGTCCTAGTCGTTTTAACTGTCGCTCCGATTTGATTAAACATACATCAACACATTCTAATGCTAAGCCTCACGTATGTGATATATGTGGTTCCCGTTTTACGCGAGCTTATTCATTACAAAAACACAAGCTGTTACATTCTGGAGAGCGACCATTTAAATGTGATCAATGTAGTATGACaTTTGCTATTATTTATCATTTGCGACGACACATGCGTACCCATACAGGCGAAAAACcttataaatgcaaatattgcGAACGTGCCTATGCAGAAAGTGGAgatttaacaaaacatttaaggACTCATGTTGGTGAAAATACCTATATGTGTGATCAATGTCCTATGGCTTTTAAATATCAAGCCGAGTTAAGACAACATCAATCGGAACATTATAAAATGGCCCAAAAACTCCTACTAGAACAAGCACAAAAGATGTCTGAAGAAGCGCAACAACAAGAAATGACTGAACTGGCACATCAGCCACAGCACCATGAGCAGCCACAACAACTGCCCATACGAGATCATAACCAACAATTAAATGTAACAGATCAAAATCAACATTTAACAATTGGACTACCATGTCAACAGCAGCAAATGTCATTGATAGATCACACTCATCAACAATTACCGACAATACAAGAGCAAACACAGCAGCATCATATAAAAATTGATGAAGTAGCCCAACAAGGCAATTTAGATATAAAGAATCTCACAgcttaa
Protein Sequence
MSGDLSKKCRTCLCDSHIFHQLDDYLEGNYKILEMLDEIVPQIFIKNTSNFSTLVCQSCVDKLETSYKFQQLCIVTNNRLHDLMGIETAEPKLEKLLDPLTGDDSFKMKQEIMDDACFECEINPEDLEEVMKSDNDWGPFQDNDYDTDSSNEKLSVLKERKTKKTPLKIEEIEKPNKKNRRKGHFPCTECGKVFDRIYRLKRHGAVHTKLRPYRCEICKYSYAAEKTYNAHILTHENGKVINKVEELEDDDKNESKELNVSIKTNESKEENDTAKESQTFQCPDCPKYFEKKASLSAHYKVHTKKPKSISNKQFKNEISLEMEKLAENLENNKEMEVSDMEDVPKVIVKEEIEVTPQIYEEPMNDFDDNMEWFNNDYDDSDDDSEKNVFDKPGAKQPKNIDFVDTGIGEIEKPNSSNKRNGTFPCEVCGKVFDRPYRLKRHSSVHSLARPHECEICKYRFATINILKAHLIQHEGDGTGNLASQSRPEGFKCPDCPRRFEKQASLSAHRQIHTRNATEANYPCMVCQRPFMSVRSLTEHITNKHPEVEKHKCDQCEKTFVLHAHLVEHLNRHKGNRNLVCLICEKEFGYTNTLKEHMRTHSGESPYLCPQCGKTFRSASNLRQHMERHTGLKKYQCPECPSRFNCRSDLIKHTSTHSNAKPHVCDICGSRFTRAYSLQKHKLLHSGERPFKCDQCSMTFAIIYHLRRHMRTHTGEKPYKCKYCERAYAESGDLTKHLRTHVGENTYMCDQCPMAFKYQAELRQHQSEHYKMAQKLLLEQAQKMSEEAQQQEMTELAHQPQHHEQPQQLPIRDHNQQLNVTDQNQHLTIGLPCQQQQMSLIDHTHQQLPTIQEQTQQHHIKIDEVAQQGNLDIKNLTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00892977;
90% Identity
-
80% Identity
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