Basic Information

Gene Symbol
-
Assembly
GCA_035586675.1
Location
JAXIUT010000009.1:2305056-2311149[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.17 22 6.8 3.7 1 23 345 367 345 367 0.97
2 19 0.0077 0.98 11.1 0.3 1 23 416 438 416 438 0.98
3 19 0.021 2.7 9.7 0.2 1 20 488 507 488 509 0.93
4 19 0.00087 0.11 14.0 1.7 3 23 551 571 549 571 0.96
5 19 0.00017 0.022 16.3 0.1 1 23 613 635 613 635 0.97
6 19 0.00034 0.044 15.3 0.1 1 23 641 663 641 663 0.97
7 19 7.1e-05 0.0091 17.5 2.9 3 23 709 730 708 730 0.95
8 19 0.00047 0.06 14.9 2.4 2 23 738 760 737 760 0.95
9 19 0.00032 0.041 15.4 0.8 2 19 790 807 789 812 0.89
10 19 0.0002 0.026 16.0 1.6 1 23 844 866 844 866 0.93
11 19 0.047 6 8.6 0.1 2 20 924 942 923 942 0.95
12 19 0.00085 0.11 14.1 0.2 2 23 961 982 960 982 0.96
13 19 0.003 0.38 12.3 4.7 1 23 1017 1039 1017 1039 0.97
14 19 0.048 6.2 8.5 3.1 1 21 1058 1078 1058 1082 0.89
15 19 0.11 14 7.4 0.6 2 23 1140 1162 1139 1162 0.93
16 19 0.025 3.3 9.4 3.6 3 23 1191 1212 1189 1212 0.90
17 19 0.00023 0.029 15.9 0.3 1 23 1219 1243 1219 1243 0.96
18 19 0.049 6.3 8.5 2.5 1 23 1248 1271 1248 1271 0.97
19 19 0.02 2.5 9.8 0.3 3 23 1303 1324 1301 1324 0.95

Sequence Information

Coding Sequence
ATGGACGACGTGGTGGAGATCAGCGGCTTGGAAAACGCCTGCAGGTTATGTCTCACGACCGAGCAGACGCGCTCCTCAATTTTTGGCGTGCCGCATGTATCTGTCCCCTTCGCCGAGAAGATACGTGCCTGTCTCTCGATTCAGatttctgCAAATGACAAGTTGTCAACACTAGTATGTGCGACTTGCATAAAGAATGTGAACCATTGGCATTCTTACAAAGATACATGCTTGAAATCACAGGAGAGGCTGCAGCAATGGTTAACCAAACAGAATTCTGTTCAAcctaTTGTCACAATAAAAGAAGAACCAGTAGATGTAGAATTTCAAGatgataatttacaaattccgGCAAATGATTCTAATTCTGCAAATGTACAACcaactttagaaaataatacagtTCAGGAAGCAGAGAATAATTCATCTATTGCAAATATTGCAGTTGAAGCATTACCACAAAATCATAAAGACAATGAAAGATTTGATAGAGAAAACTTTCCAGTATTACAAGTAAAAACTGAACCTCTTGATACAGAAGATGAAGATGACTGTAATGTGGATGTTGAGTCTATTAATAGTGGAGAACTTTTGATAAATCCATTAGCAGTGGGGGTAGTTAATAGTGTTAACAATGATCGAATCATGGAAGCTGATTCGACACAAAAATTCAAAGCGAAGAAGTATGGAAGAAAGAAATTCCGTCGTGGCCCTCATACTCATTTTAGAGGGGCTCGATTGttcaaaaaaaagtgtattcattgtaaaatttacttgcaCTCCAAGTATTCATATCAACAGCACATGTCTAGATACCATGGCATTGTCAACAATGTAGGAGCAAATAGTGCACCTAAGCTTCCTGCAGTAGCAGCACCATCGAAACAAAAGTCAAAATTGACTGAACATACAATCGATATGGAGGTTGAAGACATTGCTGATTATAGACCAGAAGAtgctgaatttataaaaatgataaaaactgATCCACTGACTccagttcaaaaaagtattatagGTCAACTTAAGACTTTTTCTTGCTACTCGTGTAAGCAAACATTCTTTGATCGACGCCAAACTCTAAATCACATAAGACAACACATGCCAGATTTACGGCCGTTCACTTGCATTGCTTGCCTTACTGAATTTTCAGATAGATCTATGTATAAGTTACACTGTGGAGCATCTTTTGAGTGTGCAATGAAAATTGCTCTAGTTGTTCCTAAAGTTGgccatgaaaaatatttcacttgcAACATGTGTTTGAAACCATTGAATAATCGGCAAGAGCTCTTGACTCACTTAGCTATGCATTCTGACAAACAAAACAAAGATTTACGGCCTCCACCAAAACTCAAGCCTATAACTCCAACAACAACTTCTAGAATTGATGCATCCACtttaaagaaatcaatttcaaatgtGGCAGGACCTTATATGAATGGAGATCCAGCACACAATCACATGTGCGATCTTTGTGGAATGATTTACAGATATAAGCCTAATATGATCAAGCATCGGGAACTCTGTTTAACTTTACCAGAAAATACTAGAACTTCCTACAGATGTGTTCAATGCAGTATGACTTATCTTGTGTTCAAGAAGTTTTATATTCACGTATTTTACGAACATAAAAAGCGAGAGATCATTTGCTTCATTTGTCATGAAAGATTCACCTCTGCTGATGAGTATCAAGTTCATCATGAAACACATCGTGAAATTGTCAACCCAGAAAATGCAGATGAAAACGTTAacgaaatatctcaaaatagTAGTGCTATGGATGCAGATCCGAATGATGCATCGCATCATACAGTCGACGAAAGTGGAAAGCCTTTTAACTGTGCACTCTgcggagaaaattttgcaacaaaGGGTGAACTTACTGAGCATAGAAATCTTCATCTCAAAGTAAAGATTTATTCATGCGTCATATGCCGAAGTATGTTTAGTAGCTCTGGAGCTTTGGAAGCACACATGAAGGATCACGGAATTGATGATGCTGCTGAACAAAATGCTAATAGTTCATGCGTTGAATATGGCCGAGGCCATCGGTCACAAAATTCATCGCTTAATGAGTCTTCTTTATCTGCTACATCGGACCCTGGAGGTCGATTCAATCACTGCTATCAATGTGGCAAAAACTTCTCGAATTATGCCAATCTGAAAAGACATGAAAGAAACCTGCACATTAAAGCAAGGCGGCGTTGGAGTTGCCATGATTGCAAGAGACGATTCAAATCATTAGAAACATATAATGAGCACTTGAGGCTGGAACACTCTTCAGAACCACAAGTACAACAATCTACTCCTAATatgCCTCCTGCCCAACCTCAAATATCAACGAGTACTGGTAAACCGCTGATGCAGTGTCCAAAGTGCCCAAAGACGTTCGCATACCAGGGTAATCTTATTCTACACTGTCAGAACGTGCATAAGGAGAATCATTTTGAACGTACAAAATCAGCCGCCCCTGCGGTTCGCCGATCGGCTCCTCCTTTGTCACGCATCTTACCAGTGGCTCGTGGCCATTCGTGTAATGTATGTGGCAAGACTTTCCGAGAAGAGCAATCACTGAAGACCCATCGTGGCTGGCATCTCCGAACGAATTACCGACTCAAGGCAgataaaaatacaagtttaAACGAAAACTTAATGACTGGACCCGGATATACAGTCAATCTAGCAAATACACCGAAACCAGCAAAAGCAAGGAAATCTTTCCCCAATAATCCTTCACAAAAGCAATTGAACTTGATTGGACCATTACAGTGTCAAGTCTGTGACGATCGTTTTTCGGATGTAGCAGAGTTGAGAAAACATCTCTGGGATGTTCACTGCGCCCGCAATAAACCTGAGAAGAATTTCGCAAGCGAGTTACAGTGTGAACTGTGTACTAACAAATTTTCTGATGAGGAGGCATTAAAAGAACACATGCAGTGGCATTCGGAAAATCCTATTCTTAGTTCTCCCAATACTAACAGTGGTAACATTAACAGCATCGTTCAAGAAGCAAACTCTATTGTTCCTGAACCaccaaaaaagaatttccatTGTGATGTTTGCGGTAAATATTACAGCAATCGCAAACTCTTCTTACGCCACAAAAAACTTCACAAAGTTCTTCCTGCTTCAACGATGATGAACTTCCAGTCTTTACAAAACAAACGACATTACTGTGTTACTTGTCAGAAAAACTTTGCTAATGATGCTTCGTTAAAGAGACACAAGGCTTCTCCTTGTCATTTAAGTAATGTCCGCGCACAAACGGCTATGCCAATCAAGAAGATAACAACAACAGCACTTGTACACCAGCCACCCGATGGAGATTTTGATCTATCGACTGTAAAGAAGGAACCAGGCGTTGAAGATGAGGCACCGAATCAGCCGGTACCAGCTGCAAAGAAGAGGCCCGTCACATGTCATATTTGCAGAATGATCTTTCCCAATATGAGCGTATTGTATCAACATAAACAACTTGTGCACAAAGTGCATCCTAGTAAAGATAGGCTCGGTGCTCCAAGCACGAATGAATGTGTACCTCTTATGAGTCCCGAAGGTTTAGTTTGCTGCAATTTGTGCGGTAAGCAATTCCCTGGAATCTCAAATCTCAAACAGCATTTCTCTCATAAACACAAAGTAAAAACTGCAACGTTTCCTTGCACTTCATCAGGCTGTAAACTCGTTTTCAGTAGTGCAAGCTCTCTCAAAAGTCACGAGTTGACGCACTCAAGTATAATGTTTAATTGCCGTATGTGCGATAAGCacgttttttcaaaagttgCCATTACCAAACACATGACGACCATGCACAAAGCGATTTATCAATCCGGAGTTGCTAAGAACACATTGTGGGCTGAAACAGACTTGGCATCTTACAACGTTAAGAATTGTCAAAGCACCGCCTGTCCGAAATGTAAAGTCAAGTATCCTAATTTACGAGCGCTGAAAATTCACTACAtcaaatttcatgaaaatggAGTGTAG
Protein Sequence
MDDVVEISGLENACRLCLTTEQTRSSIFGVPHVSVPFAEKIRACLSIQISANDKLSTLVCATCIKNVNHWHSYKDTCLKSQERLQQWLTKQNSVQPIVTIKEEPVDVEFQDDNLQIPANDSNSANVQPTLENNTVQEAENNSSIANIAVEALPQNHKDNERFDRENFPVLQVKTEPLDTEDEDDCNVDVESINSGELLINPLAVGVVNSVNNDRIMEADSTQKFKAKKYGRKKFRRGPHTHFRGARLFKKKCIHCKIYLHSKYSYQQHMSRYHGIVNNVGANSAPKLPAVAAPSKQKSKLTEHTIDMEVEDIADYRPEDAEFIKMIKTDPLTPVQKSIIGQLKTFSCYSCKQTFFDRRQTLNHIRQHMPDLRPFTCIACLTEFSDRSMYKLHCGASFECAMKIALVVPKVGHEKYFTCNMCLKPLNNRQELLTHLAMHSDKQNKDLRPPPKLKPITPTTTSRIDASTLKKSISNVAGPYMNGDPAHNHMCDLCGMIYRYKPNMIKHRELCLTLPENTRTSYRCVQCSMTYLVFKKFYIHVFYEHKKREIICFICHERFTSADEYQVHHETHREIVNPENADENVNEISQNSSAMDADPNDASHHTVDESGKPFNCALCGENFATKGELTEHRNLHLKVKIYSCVICRSMFSSSGALEAHMKDHGIDDAAEQNANSSCVEYGRGHRSQNSSLNESSLSATSDPGGRFNHCYQCGKNFSNYANLKRHERNLHIKARRRWSCHDCKRRFKSLETYNEHLRLEHSSEPQVQQSTPNMPPAQPQISTSTGKPLMQCPKCPKTFAYQGNLILHCQNVHKENHFERTKSAAPAVRRSAPPLSRILPVARGHSCNVCGKTFREEQSLKTHRGWHLRTNYRLKADKNTSLNENLMTGPGYTVNLANTPKPAKARKSFPNNPSQKQLNLIGPLQCQVCDDRFSDVAELRKHLWDVHCARNKPEKNFASELQCELCTNKFSDEEALKEHMQWHSENPILSSPNTNSGNINSIVQEANSIVPEPPKKNFHCDVCGKYYSNRKLFLRHKKLHKVLPASTMMNFQSLQNKRHYCVTCQKNFANDASLKRHKASPCHLSNVRAQTAMPIKKITTTALVHQPPDGDFDLSTVKKEPGVEDEAPNQPVPAAKKRPVTCHICRMIFPNMSVLYQHKQLVHKVHPSKDRLGAPSTNECVPLMSPEGLVCCNLCGKQFPGISNLKQHFSHKHKVKTATFPCTSSGCKLVFSSASSLKSHELTHSSIMFNCRMCDKHVFSKVAITKHMTTMHKAIYQSGVAKNTLWAETDLASYNVKNCQSTACPKCKVKYPNLRALKIHYIKFHENGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01380793;
90% Identity
iTF_00713126;
80% Identity
-