Basic Information

Transcription Factor Domain

TF Family: PC4
Domain: PC4 domain
PFAM: PF02229
TF Group: Unclassified Structure
Description: This domain is found at the C-terminal end of Activated RNA polymerase II transcriptional coactivator p15 from humans, YdbC from Lactococcus lactis, and other PC4 family members. p15 has a bipartite structure composed of an N-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain [1-4]. Activity is controlled by protein kinases that target the regulatory domain.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.27 8.2e+03 -2.9 0.2 26 37 43 55 41 55 0.67

2 3 0.45 1.3e+04 -3.6 0.9 28 37 69 79 67 79 0.70

3 3 1.7e-23 5.1e-19 68.2 0.4 1 50 84 135 84 137 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.27	8.2e+03	-2.9	0.2	26	37	43	55	41	55	0.67
2	3	0.45	1.3e+04	-3.6	0.9	28	37	69	79	67	79	0.70
3	3	1.7e-23	5.1e-19	68.2	0.4	1	50	84	135	84	137	0.96

Coding Sequence: ATGCCCAAATCAAAGGAAATGATTTCTGATGATGATAGCAGCGCCAGTTCATCTGACCAAGAAAAGGAGAAGAGCAAGCCCAAGaagcaagaaaagaaaaagcctGAAAGTTCAGCAAGCGAAGTATCTGAGGACGAGtcagaagaagaaaagaaatctaaaaagAGACCAAAGAAAGCTAGCGATGATAAAACATCAAACAAAAAAGCTAAGAAAGAAACGAAACCTAGTGATAAAGAGGAAGAGTCTTGGGATATAGGTAACAGAAAGATGGTTACTGTGCGTCCCTTTAGGGGAAAATACTATGTTGACATTCGGGAAATGTACATCGATAATAGCTCAGGAGAAATGAAGCCTGGAAAAAAAGgTATATTTATGTCACAAGAAAACTGGAAAGCTTTAAAAGGTGTGATGGATGAAGTAGACGAGTTTTTGAAGTCCAAGTGttaa
Protein Sequence: MPKSKEMISDDDSSASSSDQEKEKSKPKKQEKKKPESSASEVSEDESEEEKKSKKRPKKASDDKTSNKKAKKETKPSDKEEESWDIGNRKMVTVRPFRGKYYVDIREMYIDNSSGEMKPGKKGIFMSQENWKALKGVMDEVDEFLKSKC

Sequence clustering based on sequence similarity using MMseqs2