Basic Information

Transcription Factor Domain

TF Family: PC4
Domain: PC4 domain
PFAM: PF02229
TF Group: Unclassified Structure
Description: This domain is found at the C-terminal end of Activated RNA polymerase II transcriptional coactivator p15 from humans, YdbC from Lactococcus lactis, and other PC4 family members. p15 has a bipartite structure composed of an N-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain [1-4]. Activity is controlled by protein kinases that target the regulatory domain.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 7.9e-05 1.6 9.4 0.1 9 25 12 28 5 33 0.92

2 9 0.01 2.1e+02 2.7 0.0 9 25 34 50 29 53 0.89

3 9 0.0041 85 3.9 0.0 9 25 45 61 40 63 0.91

4 9 0.0041 85 3.9 0.0 9 25 67 83 62 85 0.91

5 9 0.005 1e+02 3.7 0.1 9 25 89 105 84 107 0.91

6 9 0.0043 90 3.9 0.0 9 25 111 127 107 129 0.92

7 9 0.0042 86 3.9 0.0 9 25 133 149 128 151 0.91

8 9 0.0052 1.1e+02 3.6 0.1 9 25 155 171 151 173 0.91

9 9 0.0042 86 3.9 0.0 9 25 177 193 172 195 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	7.9e-05	1.6	9.4	0.1	9	25	12	28	5	33	0.92
2	9	0.01	2.1e+02	2.7	0.0	9	25	34	50	29	53	0.89
3	9	0.0041	85	3.9	0.0	9	25	45	61	40	63	0.91
4	9	0.0041	85	3.9	0.0	9	25	67	83	62	85	0.91
5	9	0.005	1e+02	3.7	0.1	9	25	89	105	84	107	0.91
6	9	0.0043	90	3.9	0.0	9	25	111	127	107	129	0.92
7	9	0.0042	86	3.9	0.0	9	25	133	149	128	151	0.91
8	9	0.0052	1.1e+02	3.6	0.1	9	25	155	171	151	173	0.91
9	9	0.0042	86	3.9	0.0	9	25	177	193	172	195	0.91

Coding Sequence: ATGAATGTACGGGACTGGCAAGCTATTCTAGCTGTAAATATACGGGACTGGCAAGATATTGTAGCTGTAAATATACGGGACTGGCAAGCTATTCTAGATATAAATATACGGGACTGGCAAGCTATTCTAGCTGTAAATGTACGGGACTGGCAAGCTATTCTAGATATAAATATACGGGACTGGCAAGCTATTCTAGCTGTAAATGTACGGGACTGGCAAGCTATTCTAGATATAAATATACGGGACTGGCAAGCTATTCTAGCTGTAAATGTACGGGACTGGCAAACTATTCTAGATATAAATATACGGGACTGGCAAGCTATTCTAGCTGTAAATGTACGGGACTGGCAAGCTATTCTAGATATAAATATACGGGACTGGCAAGCTATTCTAGCTGTAAATGTACGGGACTGGCAAGCTATTCTAGATATAAATATACGGGACTGGCAAGCTATTCTAGCTGTAAATGTACGGGACTGGCAAACTATTCTAGATATAAATATACGGGACTGGCAAGCTATTCTAGCTGTAAATGTACGGGACTGGCAAGCTATTCTAGATATAAATATACGGGACTGGCAAGCTATTCTAGCTATAAATGTACGGGACTGA
Protein Sequence: MNVRDWQAILAVNIRDWQDIVAVNIRDWQAILDINIRDWQAILAVNVRDWQAILDINIRDWQAILAVNVRDWQAILDINIRDWQAILAVNVRDWQTILDINIRDWQAILAVNVRDWQAILDINIRDWQAILAVNVRDWQAILDINIRDWQAILAVNVRDWQTILDINIRDWQAILAVNVRDWQAILDINIRDWQAILAINVRD

Sequence clustering based on sequence similarity using MMseqs2