Basic Information

Gene Symbol
-
Assembly
GCA_955876795.1
Location
OY041605.1:10543521-10566601[-]

Transcription Factor Domain

TF Family
AF-4
Domain
AF-4 domain
PFAM
PF05110
TF Group
Unclassified Structure
Description
This family consists of AF4 (Proto-oncogene AF4) and FMR2 (Fragile X syndrome) nuclear proteins. These proteins have been linked to human diseases such as acute lymphoblastic leukaemia and mental disabilities [1]. The family also contains a Drosophila AF4 protein homologue Lilliputian which contains an AT-hook domain. Lilliputian represents a novel pair-rule gene that acts in cytoskeleton regulation, segmentation and morphogenesis in Drosophila [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 7.9e-11 2.7e-06 27.8 0.0 3 81 45 125 43 157 0.83

Sequence Information

Coding Sequence
ATGAACGCCCCGGaggtgccgccgccgccgttccgACTGTGTCTTAGATACGACAAGTGGGACCGAGACCGGGACCGGGGCGGGGGCGGCAGTGGCGGCGGCGgctcgggcgcgggcggcgcgtgGTCGAGCCGCGACCGGGAGCGCGACCGCGAGCGCGAGCGCCAGGCGCGTGCTCACCAGATGTCGCACGCTCACGCCGCCGAGCCCGACGCCTCGTCTCTGTTCCCGGCACCAGTTAGGGTGACTGGCCAGCGAGACAAAGTCAGCCAGCAGATCCAGCATAAACTCGGCGACTACTATCTCGCGCAGACGTTCATCGACGACCCTAGCAAGTCGATCGGCATTTGCGCGGAACCACCAAGTCCTGCTCCATATTTCCTTGAGCCGGCGAGACCGGAGCCTCGCATAAAAACGTGTGTACACAAGAAAAGGCTACACATTATGCCGGTGCCCCTCGCGGAGAATATGCCGCTATTTGTCCATGTCTGA
Protein Sequence
MNAPEVPPPPFRLCLRYDKWDRDRDRGGGGSGGGGSGAGGAWSSRDRERDRERERQARAHQMSHAHAAEPDASSLFPAPVRVTGQRDKVSQQIQHKLGDYYLAQTFIDDPSKSIGICAEPPSPAPYFLEPARPEPRIKTCVHKKRLHIMPVPLAENMPLFVHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00700133;
90% Identity
iTF_00703975;
80% Identity
-