Basic Information

Insect: Eupithecia subumbrata
Gene Symbol: Bcl11a
Assembly: GCA_949316285.1
Location: OX438635.1:6766695-6774257[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.26 22 6.7 1.6 1 23 220 243 220 243 0.94

2 11 1.9 1.6e+02 3.9 0.2 2 23 251 271 250 273 0.87

3 11 4.9 4.2e+02 2.6 2.1 2 23 276 298 275 298 0.87

4 11 0.03 2.6 9.6 4.9 1 23 308 330 308 330 0.98

5 11 0.00013 0.011 17.0 0.2 2 23 335 357 334 357 0.95

6 11 0.0039 0.34 12.4 6.5 1 19 364 382 364 387 0.91

7 11 0.0089 0.76 11.3 6.6 3 23 394 414 393 414 0.97

8 11 2.8e-05 0.0024 19.1 0.1 1 23 425 448 425 448 0.94

9 11 1.5e-05 0.0013 20.0 2.9 1 23 454 477 454 477 0.95

10 11 0.00031 0.027 15.8 0.1 3 23 488 508 487 508 0.98

11 11 0.00025 0.022 16.1 0.1 2 23 515 537 514 537 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.26	22	6.7	1.6	1	23	220	243	220	243	0.94
2	11	1.9	1.6e+02	3.9	0.2	2	23	251	271	250	273	0.87
3	11	4.9	4.2e+02	2.6	2.1	2	23	276	298	275	298	0.87
4	11	0.03	2.6	9.6	4.9	1	23	308	330	308	330	0.98
5	11	0.00013	0.011	17.0	0.2	2	23	335	357	334	357	0.95
6	11	0.0039	0.34	12.4	6.5	1	19	364	382	364	387	0.91
7	11	0.0089	0.76	11.3	6.6	3	23	394	414	393	414	0.97
8	11	2.8e-05	0.0024	19.1	0.1	1	23	425	448	425	448	0.94
9	11	1.5e-05	0.0013	20.0	2.9	1	23	454	477	454	477	0.95
10	11	0.00031	0.027	15.8	0.1	3	23	488	508	487	508	0.98
11	11	0.00025	0.022	16.1	0.1	2	23	515	537	514	537	0.95

Sequence Information

Coding Sequence: ATGGAATTCCAATCGGCAAGTTCGGCAACATCTATAACGGAACATTACAGTTCGTTCTACGATGAAGCAATGAAAATGAATTGTCACAAGATTTGTTGCTGCTGTCTGTCAAAGAATGCAAGAATGGTCGGCCTCCAATATTGCAAACATGCTGATTTCTTACAAAACTTTCCACAGATGGATCTGTCACGGAAGACTGTATGCCTGCTCTGCCACAGTATGcttgagaaaataaaaatatttcggaAACAAATCATAGATAGCACCAACATTTTAAACAGTCGGTTACCCCACATTTTACCAACAAGGTTGCATAAACTACAGATAACAGAGATAAAAACAACTTCGAAATCTGAATTTGAAGACGAAACAACAGAAGAAGTTACTCTGAAATTAGAGCTTGACCCGACGAGCTCCTTAGCATTCGAAACAGAAGTAAAAATAGAACACACCTCCAGTTCAGAAGAATGTGAAAACGACACATCGCCATGTATAGCGGAAAACGTCAAAAATGATACTAAAAGGAAAAGATGCAAACAATCTCATGAAGATGATGATAAATACAAAGGGAAAATACTGATCTACAATTTAACAAGAGATGAGTTGGAAGAAGAAAGAGATATAGAGAGGAAGAAGGAGACTTACGTAAAACTTccttataaatgtgaaagttgtATCAAAGGATTTGATCATGAGGTCACTTTGATGAAACATAATGAGAAACAACATCGTCAGaaaaaaggtGGTATTCAATGTGACGTCTGCAAAACTATACTGGTACCGCTTTCATACAAGGAGCACATACGAAGACATTACAGAAGACTTCAATGTGCGCTCTGCGGGAAGCGCTCCCATGACATCTACTCCATCTCTCATCACTTCAACCAGGAGCACAGCGAGGCAGGAGTCATCCCTCACCAGTTTCAATGCAGTGACTGCGAGTTTACTTGTAGTTCCAACCGCGCCTACCGCTATCACCGCGACAAACACAAGCAGAAGTCGCAATGCACAGAGTGTGGCAACACTTATGTCAACGCGACGACGCTACGCGTGCATATGCTTAACGTGCATGATCAAACAACAGGGAAATACAAATGCTCGCAATGTGACAAGTCGTACTGCAGTAAGTCAGGTTTGTTCAGCCACTGTTCTTCAGCGCACTCGGACAGCGGCGCGTACTGCGTGGAGTGCAAGACGCACTTCCGGACAAGGCACGGCCTTGCGCATCATCTCAACACGCATTCTAAACATGTCGAtgtgaaccgtaaaagATTTGAATGTGCTGACTGCGATGCCAAGTTCATACGGAAGTCCTCACTCCAAGAGCACATCGACTGGAGCCATCTCAAGAACGTCGCTCATCAGTGCAGTCAATGTGATAAGGTGTTCAAAAGTGTAAAGTCTCTGAAGAAGCACATAAGCTATGTGCACGAGAAGAAGCGACCTCCGCGGGACAAGATCTGTGACTATTGTGGCCGAGGGTTCACGACAATTCCGATCCTCCGTAACCACATCCGCACGCATACAGGCGAGCGACCGCTGACCTGCCCGCTTTGCGACGCTACCTTCGCGCAGTCCGCCTCCTTGTATACCCACACAAAACTAGTTCATAAGCAGTCTATAGCTAACCACTGA
Protein Sequence: MEFQSASSATSITEHYSSFYDEAMKMNCHKICCCCLSKNARMVGLQYCKHADFLQNFPQMDLSRKTVCLLCHSMLEKIKIFRKQIIDSTNILNSRLPHILPTRLHKLQITEIKTTSKSEFEDETTEEVTLKLELDPTSSLAFETEVKIEHTSSSEECENDTSPCIAENVKNDTKRKRCKQSHEDDDKYKGKILIYNLTRDELEEERDIERKKETYVKLPYKCESCIKGFDHEVTLMKHNEKQHRQKKGGIQCDVCKTILVPLSYKEHIRRHYRRLQCALCGKRSHDIYSISHHFNQEHSEAGVIPHQFQCSDCEFTCSSNRAYRYHRDKHKQKSQCTECGNTYVNATTLRVHMLNVHDQTTGKYKCSQCDKSYCSKSGLFSHCSSAHSDSGAYCVECKTHFRTRHGLAHHLNTHSKHVDVNRKRFECADCDAKFIRKSSLQEHIDWSHLKNVAHQCSQCDKVFKSVKSLKKHISYVHEKKRPPRDKICDYCGRGFTTIPILRNHIRTHTGERPLTCPLCDATFAQSASLYTHTKLVHKQSIANH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00699537;
90% Identity: iTF_00703340;
80% Identity: -