Esub020603.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eupithecia subumbrata
Gene Symbol
L
Assembly
GCA_949316285.1
Location
OX438644.1:28487498-28517205[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.8e-06 0.00015 22.9 1.7 1 23 84 106 84 106 0.99
2 16 0.75 64 5.2 5.8 1 23 112 134 112 134 0.97
3 16 1e-05 0.00086 20.5 4.1 1 23 140 162 140 162 0.99
4 16 3.1e-05 0.0026 19.0 0.1 1 23 168 190 168 190 0.98
5 16 2.7e-05 0.0023 19.2 0.1 2 23 206 228 205 228 0.95
6 16 3.6 3.1e+02 3.1 0.3 3 23 252 274 250 274 0.79
7 16 0.36 31 6.2 0.0 3 23 321 341 320 341 0.97
8 16 0.2 17 7.0 0.0 3 23 356 376 355 376 0.91
9 16 5.5e-05 0.0047 18.2 0.6 1 23 384 407 384 407 0.94
10 16 0.014 1.2 10.7 0.1 1 23 412 435 412 435 0.92
11 16 0.0019 0.16 13.4 0.2 1 23 489 513 489 514 0.96
12 16 0.0012 0.1 14.0 0.0 2 23 564 585 563 585 0.96
13 16 0.069 5.9 8.5 0.0 1 23 593 615 593 615 0.97
14 16 1 89 4.8 0.3 1 23 719 741 719 741 0.94
15 16 0.0041 0.35 12.3 0.1 1 20 749 768 749 771 0.95
16 16 0.14 12 7.5 0.3 1 23 778 800 778 800 0.94

Sequence Information

Coding Sequence
ATGCTATTCAAGGGGAACAGCAGCCGGCTGGAGCACCTCATCGAGAAGATACAGGCTAACAAAGAGAACCACGACGTCATCGCTGAAGATTTAAAAGAGGCGCTGGGCAGCGTGGGCAGCGCGGCGGGAAGCTCCTGGCCGTCGTCGACGCCGGAGCCGTCCCCGTCGCCGGCGTCCACGCCCTCCGCCGACGCCGCCGAAGCCGACGCCGAACCGCCCTTCACCATCGGCGCTACGGAACACACACCTTACCAGTGCCAGTTCTGCGACAAGGCTTTCCCGAGGCTGTCTTATCTGAAGAAACATGAACAGACCCACTCGGACCAAATGCCGTTCCGCTGCGAATTCTGCTCGCGCCTGTTCAAGCACAAGCGCTCCCGCGACCGGCACGTGAAGCTGCACACGGGGGACAGGAAGTACCGCTGTGCTCATTGCGAGTCTGCCTTTTCAAGGAGCGACCATCTAAAAATCCACATGAAAACCCACGACAACCAGAAGCCCTTCCAATGCACGGTGTGCAACCGCGGCTACAACACCGCGGCGGCTCTGACGTCACACATGCAAGGACACAAGAGGGATAGAGAGGGGCGCGAGCCTGACAAAAGGAGGTCGATGCGTTGCCTGCGATGCGGGGAAGCTTTCCGGAGACCGGATCTACTGCAGGCTCACATGGCCAGCACCCACGGCGTGGAGGCGGCCGCCCTCACTCCGCCTCGCCGCGTCGCCTCTCAACCACCGCCAACACTCCTCGCCTGCATGTACTGCACTCGAGACACCTTCACCAGCATGGAGCAACTACAGCTACACGTCCGAGCCTCTCACTCTGCCCTACTCAACGGTGGCTCTCCGGAGCAGCCGACTCCGACCGATCTTAGTCGAAGACCGTCCGAAGACGCTCCACCCGCCAAACGACCACGCTCCGGAACTCCTCAAACTACACTATCCCCCAACACGCTTCTATGCAACCAGTGCGACGCAGCGCTACCGGACTTCGAAGCGTTCCGGGCACATTTGAAAGGTCATATCGACGAAGGGGGAGAGTTAACCAGAACAAGCCCGGCTCCATGCGTCCACTGTGGTGCTACCTTCGCTGATGCGGCCGCATCGGAACGTCACCTCACTGCGCATTACTTGGCAGTCTCCTGTGAATACACTTGCCACAGCTGCGCTAGAAGTTTCCCTACTCCAGATGATCTGCAGAAGCACCTGTTGGATCTGCATGCTCATCATCTGTACCGGTGTTCGCTTTGCAAGGAGGTGTTTGACTCTAAAGTAGCGATTCAGGTTCATTTCGCCGTAGCACACAGTGGTGAGAATAAAGTGTGGGTTTGCCGAGGGTGCGGCAGCGGCGCCGGAGCCCTACGCTCGGAGGCCGACGGCGTCGCCCACGTGCGGTCCCGGCACGCGGGCGCAAGGTGCTCCTGCGGCGCCCTGCTGGGAGGCCCGAGGCTGCGTCCCAGGGCTTACAGGTGTCCGGTGCCGACCTGCACTGATGCATTTGCCGTTCAGTATCTGCTAGAAAGGCATATGCAAGTGCATCATGCTATGGCGCAACAGGTGCTCAACGGCGAGATAGGCCGACCAAAGCGCGTGGAAAACAACAACGGCATAGAAGATGGCGCCTGTTCCCCTTGCACCGCCGAGCCGGTAGCCGAGGAGCGCAGACGGAAGAACGGAGCAGTGGCGCTGCAGTGCGCGTACTGCGGGGAGCGGGCAAGGTCCCGGGCGGAGTTAGAGGCGCACACTAGGGCTCACTCGGGGGCCGCGGCCGCGCGGCACAAGTGTCTCATATGCGACGAGGTGCTGCCCTCCGCTGCCGTGCTGGCTGAGCACAAACTGACGCACTGCAAGGTGGTGGCCGGTGATACTTGCTCCCGCTGCCGCGCGCGGCTCCTCTCCGAGGAGTCGTTCCTGGCGCACATGGCGCGGCACCAGCCCGCGCTGCCCGCGCCCTGCGTCGTCTGCCGGCAGACGCTCGCCTCCGAGGCCGAGGCCAGGCTGCACGCGCGCTTCCATCTGCGACCCAGCGACACTGACCAAAGATGTGCAATCTGCCTGCGCGCGCTCCCGGAAGGCGAGGGCGGCGAGGGCGCGCGCGCTTGCTCGTCGTGCTACGCGCGCCACGCCGCCCCGCGCTCCGCGCCGCCCGCCGACCACGACTGCCGGCTCTGTCGCCGGGCCCTCGGCTCCCCCACGAGGCTGCAAGCCCATCTCATAGAACACACCTTCGCCGGCATAGGGGCTTTTACTTGCTACCTCTGCTCGGCGGTGTTCACGAGCGCGGCGGGCCTGCAGCGGCATCTACCGGAGCACGCCTCGGCGCCGCGGCCGTACGACTGCGCCCGATGCGGTATGAAATTCTTCTTCCGAGCAGAGTTAGATAATCACGCCTTCGTGCATTTGGAAGAGGCCGAGATAGCGCAGCGAGCGTTCTACGAGGCCTACGCGCGTGGAGCGGCCAACGCCTGGGCGGCCCTAGCGCCTCCGGAGCCGGCCCACGTGACCACTCCGGCGCCGGAGGTGAAACAGGAACCAGAGATAAAGGAGGAACGTAACGATGAGTATATCGAGGTTGGATCACCGCCGCCTGTGACGCAGCCGGTGACTACTCCCCCGCCCGTCGTCAAACAAGAGAAGCCTGATGAAGATTGA
Protein Sequence
MLFKGNSSRLEHLIEKIQANKENHDVIAEDLKEALGSVGSAAGSSWPSSTPEPSPSPASTPSADAAEADAEPPFTIGATEHTPYQCQFCDKAFPRLSYLKKHEQTHSDQMPFRCEFCSRLFKHKRSRDRHVKLHTGDRKYRCAHCESAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQGHKRDREGREPDKRRSMRCLRCGEAFRRPDLLQAHMASTHGVEAAALTPPRRVASQPPPTLLACMYCTRDTFTSMEQLQLHVRASHSALLNGGSPEQPTPTDLSRRPSEDAPPAKRPRSGTPQTTLSPNTLLCNQCDAALPDFEAFRAHLKGHIDEGGELTRTSPAPCVHCGATFADAAASERHLTAHYLAVSCEYTCHSCARSFPTPDDLQKHLLDLHAHHLYRCSLCKEVFDSKVAIQVHFAVAHSGENKVWVCRGCGSGAGALRSEADGVAHVRSRHAGARCSCGALLGGPRLRPRAYRCPVPTCTDAFAVQYLLERHMQVHHAMAQQVLNGEIGRPKRVENNNGIEDGACSPCTAEPVAEERRRKNGAVALQCAYCGERARSRAELEAHTRAHSGAAAARHKCLICDEVLPSAAVLAEHKLTHCKVVAGDTCSRCRARLLSEESFLAHMARHQPALPAPCVVCRQTLASEAEARLHARFHLRPSDTDQRCAICLRALPEGEGGEGARACSSCYARHAAPRSAPPADHDCRLCRRALGSPTRLQAHLIEHTFAGIGAFTCYLCSAVFTSAAGLQRHLPEHASAPRPYDCARCGMKFFFRAELDNHAFVHLEEAEIAQRAFYEAYARGAANAWAALAPPEPAHVTTPAPEVKQEPEIKEERNDEYIEVGSPPPVTQPVTTPPPVVKQEKPDED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00635642;
90% Identity
iTF_01429280;
80% Identity
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