Esub002736.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eupithecia subumbrata
Gene Symbol
-
Assembly
GCA_949316285.1
Location
OX438629.1:8668733-8688232[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.00012 0.01 17.1 0.1 3 23 126 146 125 146 0.97
2 19 1.1e-06 9.3e-05 23.6 1.2 1 23 152 174 152 174 0.99
3 19 6.8e-06 0.00058 21.1 2.7 1 23 180 202 180 202 0.99
4 19 6e-06 0.00051 21.2 2.4 1 23 217 239 217 239 0.98
5 19 0.00017 0.015 16.6 0.6 1 23 254 276 254 276 0.98
6 19 6.2e-05 0.0053 18.1 3.1 1 23 291 313 291 313 0.98
7 19 7.7e-07 6.6e-05 24.0 1.5 1 23 328 350 328 350 0.99
8 19 0.00019 0.016 16.5 2.8 1 23 356 378 356 378 0.98
9 19 0.0001 0.0085 17.4 0.6 1 23 385 407 385 407 0.98
10 19 1.4e-05 0.0012 20.1 2.1 1 23 413 435 413 435 0.99
11 19 0.044 3.7 9.1 1.8 1 23 442 464 442 464 0.98
12 19 7.3e-07 6.3e-05 24.1 2.3 1 23 470 492 470 492 0.99
13 19 0.051 4.3 8.9 1.8 1 23 499 521 499 521 0.98
14 19 3e-06 0.00026 22.2 1.5 1 23 527 549 527 549 0.99
15 19 0.00057 0.049 15.0 0.7 1 23 556 578 556 578 0.99
16 19 3.3e-06 0.00028 22.1 1.9 1 23 584 606 584 606 0.98
17 19 0.0024 0.21 13.0 0.3 1 20 612 631 612 634 0.93
18 19 4e-05 0.0034 18.7 1.3 2 23 641 662 640 662 0.96
19 19 4.3e-06 0.00036 21.7 1.4 1 23 668 691 668 691 0.97

Sequence Information

Coding Sequence
ATGTTCGAACAGCAAATCAAAGCTGAACCCATgaaCTTCTACCACCCACACGTCCCCCACGTGCACCCCGGGCCGCCTACGATAGGGCGCTCGGAGTCGAATCACCACCTCATGAACCCGCATCACCACGAAGACTCCAAGGACAGCCTCATACAACATCAAGTACAACATCAGCAGGATCTCATGGAACAACATCAACAACAGGAAATGCAACAAGATGATGAGCTGAGCTTCAAAGGAATGGAAGATGAAGGTGTGGATATGGATATGGATGGCAGACAGTGTTCACagGATTTGGTGATGGACATGGGTGCAGTTCAAACAAAAATGGAAGTCAACGGTGGTCAATCCACACCAAGATCTAAACCACAAGCCTGTAAGGTTTGCGGCAAAGTCCTTTCGTCCGCTTCTTCATATTACGTCCACATGAAGCTTCATTCGGGAAACAAGCCTTTCCAATGCACAGTGTGCGACGCTGCGTTTTGCCGGAAGCCTTACCTCGAAGTCCACATGCGCACACACACAGGCGAACGCCCGTTCCAATGCGATTTGTGCCTAAAGCGCTTTACACAGAAGTCAAGTTTGAATACGCACAAGCGAGTGCACACGGATGAGCACTTGCACGCGTTGGTGGTGAAGGACCGGCCCTACAGGTGTGAACTCTGTCAGATGCGGTTCACGCAGAGTTCCAGCCTCAACAGACACAAGAAAATACACACGGAGGAACACAGACGCGCTCTGCTGGTCAAGGACCGGCCCTACCAATGCGGAATCTGCTTTGTGAGATTCACCCAGAGATCGAGTTTGGGCCGGCACGGGAAAATACATACCGAGGAGCACAGACGAGCCCTGTTAGAGAAAGTGCGGCCGTACCAGTGCCACATCTGTTTTATGCGCTTCACTCAGAAGTCCAGCCTCGGACGTCATGGGAAAATACACACTGAGGAGCACATCCAATCGCTGATCAACAAAGTGCGTCCGTATCAGTGCGACGTCTGTGACAAGCGGTTCACGCAGAAGTCCAGCCTTGGTACTCATAAGCGTATACACACCGGGGAGCGGCCGTTCCAGTGCACCGTCTGCCTCAAGTCCTTCACGCAGAAGTGCGCGCTCAATTTGCACGAAAAGATACATACGGTGCAAGGGCGTCCGTTCGCGTGCTCGCACTGCCCGGCGGCCTTCGTCCGCCGCGTCTATCTGGACACTCACTTGCGCACGCACACAGGCGAGCGGCCCTATCAGTGCGACGCCTGTCTCAAGCGATTCACGCAGAAGTCGAGCCTCAATATACATAAGAGGACGCATTCAGTCCAGGGCAGACCGTTCCAGTGCCTGTCGTGCCCCGCCGCCTTCACCTGCAAGCAATACCTGGAGATACACACGCGCACGCACACCGGCGAGCGCCCCTATCAGTGCGACATCTGCCTGAAGCGCTTTACGCAGAAGTCCAGTCTCAACATCCACAAGCGGACGCACTCAGTCCAAGGCCGGCCCTTCCAGTGCCTGCAGTGCCCGGCCGCGTTCACCTGCAAACAGTACTTGGAGATTCACAACCGCACGCACACGGGAGAGCGACCCTACCAATGCGACGTTTGCCTCAAACGATTCGCGCAAAAGTCCACACTCAACATTCACAAACGAACGCACACAGTGCAAGGGCGGCCGTACCAATGCATGGAGTGCCCAGCCGCGTTCACTTGCAAGCCGTATCTGGAGATTCACATGCGCACGCACACCGGGGAGCGCCCGTTCGAGTGCGATGTCTGTTACAAACGGTTCACGCAGAAATCTACGCTCAACATCCACAAGCGAATTCACACTGGCGAACGCCCTTACGCTTGCGATATTTGCCAGAAGCGTTTTGCTGTGAAGAGCTACGTAACAGCTCACCGATGGTCCCACGTCGCAGACAAGCCTCTGAACTGCGACCGCTGCTCGATGTCGTTCACGTCCAAGTCTCAGTTCGCGCTGCACATCCGCACGCACACGGCAGGGCCGTGCTACGAGTGCAGCGTGTGCGGACGGACCTTCGTCAGGGACAGCTACCTTATACGTCACCACAACCGCGTTCACCGCGACAACCACAGCAACATGTCAGCGAACAGTATCGGCAACTTGAACTCCGTCGCTACCAACACTAACTCCAACAacggcgggttcgattctcccGGTGGCGTCTGTGATTTGAGCTTTGTCCCGATGGTGAATCGTTATATGACGTCCCAGGGTACACAGGTGTCGATGCAAGATGCCCAGAAGATGCAGGCCATGTCACCGCAATCCATCGCCTCTATTTCCTCGCCCCCGCCACCTCATACCCCGACGCCACAGCCCCAGATGTCTGGCCCACTGCACATGGCAGACTGA
Protein Sequence
MFEQQIKAEPMNFYHPHVPHVHPGPPTIGRSESNHHLMNPHHHEDSKDSLIQHQVQHQQDLMEQHQQQEMQQDDELSFKGMEDEGVDMDMDGRQCSQDLVMDMGAVQTKMEVNGGQSTPRSKPQACKVCGKVLSSASSYYVHMKLHSGNKPFQCTVCDAAFCRKPYLEVHMRTHTGERPFQCDLCLKRFTQKSSLNTHKRVHTDEHLHALVVKDRPYRCELCQMRFTQSSSLNRHKKIHTEEHRRALLVKDRPYQCGICFVRFTQRSSLGRHGKIHTEEHRRALLEKVRPYQCHICFMRFTQKSSLGRHGKIHTEEHIQSLINKVRPYQCDVCDKRFTQKSSLGTHKRIHTGERPFQCTVCLKSFTQKCALNLHEKIHTVQGRPFACSHCPAAFVRRVYLDTHLRTHTGERPYQCDACLKRFTQKSSLNIHKRTHSVQGRPFQCLSCPAAFTCKQYLEIHTRTHTGERPYQCDICLKRFTQKSSLNIHKRTHSVQGRPFQCLQCPAAFTCKQYLEIHNRTHTGERPYQCDVCLKRFAQKSTLNIHKRTHTVQGRPYQCMECPAAFTCKPYLEIHMRTHTGERPFECDVCYKRFTQKSTLNIHKRIHTGERPYACDICQKRFAVKSYVTAHRWSHVADKPLNCDRCSMSFTSKSQFALHIRTHTAGPCYECSVCGRTFVRDSYLIRHHNRVHRDNHSNMSANSIGNLNSVATNTNSNNGGFDSPGGVCDLSFVPMVNRYMTSQGTQVSMQDAQKMQAMSPQSIASISSPPPPHTPTPQPQMSGPLHMAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00010401;
90% Identity
iTF_00737671;
80% Identity
-