Esub023241.1
Basic Information
- Insect
- Eupithecia subumbrata
- Gene Symbol
- e2f4
- Assembly
- GCA_949316285.1
- Location
- OX438646.1:13135531-13139146[-]
Transcription Factor Domain
- TF Family
- E2F
- Domain
- E2F_TDP domain
- PFAM
- PF02319
- TF Group
- Helix-turn-helix
- Description
- This family contains the transcription factor E2F and its dimerisation partners TDP1 and TDP2, which stimulate E2F-dependent transcription. E2F binds to DNA as a homodimer or as a heterodimer in association with TDP1/2, the heterodimer having increased binding efficiency. The crystal structure of an E2F4-DP2-DNA complex shows that the DNA-binding domains of the E2F and DP proteins both have a fold related to the winged-helix DNA-binding motif. Recognition of the central c/gGCGCg/c sequence of the consensus DNA-binding site is symmetric, and amino acids that contact these bases are conserved among all known E2F and DP proteins.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 2.1e-29 1.8e-25 89.3 0.4 2 65 10 74 9 74 0.98 2 2 0.014 1.3e+02 3.4 0.0 12 34 171 193 168 213 0.84
Sequence Information
- Coding Sequence
- ATGACTGatttaaaatacaaaagatACGAAAAATCACTAGGCTTACTTACAACAAAATTTGTATACCTTCTTCAAAAAGCCAAGGATGGCGTCTTAGATTTAAAAACCGCGACTAATTTATTGGCTGTGCGCCAAAAGAGAAGAATTTACGACATTACCAATGTTTTGGAGGGAATCGGGTTGAttgagaaaaagagcaaaaacAGCATTCAATGGAAAGGAGCTGGTCCTGACTGCAATAGTACTGATATCGCCAAAAGAGTTATTACTATGCGTAAACAACTAAGCCAACTTGATCAGTATGAAACAATGCTCAACAACCAGTTGCACTATATCGAAAAAAGTGTTAAAAATGTGCTGGATGACTCAGACAACCAGGACTTTTGCTATGTTTCAAAAACGGAcattcaaaattgttttaaagaCAACCAACTGCTTGTTTTGGAGGCACCTTTGGGTGCTAATTTATCTGTTGGCACTGGAGCTAATATGgaTAACGAAATGAACTTTTTCCTGCATTTAAAAGCAAATGAATCAATGGGAGTGATACATTTGAATGAAATATCAAAGAAGTTAGAagagactgatgatgatgactccaTGGACAGTGAAGTGGAAGGATTCAATACAAATTGTACCCTTAGTGCAAAACATTGTGTCCCAAGATTGAGCCCTCCAATAAGAAAATGTGACTTTGCATTCTCATTGCATGGGTCAGAAGGCTTGTGTGATCTGTTTGATATTCCTTGCTAG
- Protein Sequence
- MTDLKYKRYEKSLGLLTTKFVYLLQKAKDGVLDLKTATNLLAVRQKRRIYDITNVLEGIGLIEKKSKNSIQWKGAGPDCNSTDIAKRVITMRKQLSQLDQYETMLNNQLHYIEKSVKNVLDDSDNQDFCYVSKTDIQNCFKDNQLLVLEAPLGANLSVGTGANMDNEMNFFLHLKANESMGVIHLNEISKKLEETDDDDSMDSEVEGFNTNCTLSAKHCVPRLSPPIRKCDFAFSLHGSEGLCDLFDIPC
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00701749;
- 90% Identity
- iTF_00696294;
- 80% Identity
- -