Eint022438.1
Basic Information
- Insect
- Eupithecia inturbata
- Gene Symbol
- topi
- Assembly
- GCA_963662085.1
- Location
- OY759201.1:1791412-1813242[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.00021 0.016 16.3 2.2 1 23 240 262 240 262 0.98 2 10 0.00029 0.021 15.9 0.9 3 23 271 291 269 291 0.98 3 10 0.028 2.1 9.6 6.5 1 23 325 348 325 348 0.88 4 10 1.4e-05 0.0011 20.0 0.1 2 23 355 377 354 377 0.96 5 10 2e-05 0.0015 19.5 0.4 1 23 390 412 390 412 0.96 6 10 0.00011 0.0077 17.2 0.3 1 22 418 439 418 443 0.94 7 10 0.00016 0.012 16.7 1.8 2 23 452 474 451 474 0.96 8 10 1.3e-05 0.00097 20.1 0.8 1 23 480 503 480 503 0.97 9 10 2.5e-05 0.0018 19.2 0.4 1 23 512 534 512 534 0.98 10 10 0.04 3 9.1 0.2 1 23 540 563 540 563 0.95
Sequence Information
- Coding Sequence
- ATGGAGGTTACTGAAAATAACCAGTGTTGTTTTGGATGCTTGTCCACTGAAGATGAGTTTCATTTGCAGGAGTTTTCGCTCCAATGCGAGCCTCTAAAAACAATTTTCCAGGTTGATGTCATAGTTTTATGCACAGTTTGCAAAAGAATAGCTCAGCATGCGGAtttattcatacaaaatgtGCAGAGCAACCAGATCTTATTGCAGAACTTTCACAATGACCTCTCAGCTCTGCAAACAATCTGCCCTCAAGTCCAACCATGCATATCCCTCGCTCATGCACCACTGCCATACCTTGAGCTCCCCGGGACAGGCACCGAGGAATGCTGTATCGTCGTCGGCCCGGAGCAAAAAATTAAGATGGAGCCCAAAGAGGAATTTGATCAATTGGATGGAGAGTTTATAGATGGGAGTGATGATTTTCAGGACCCTTATGTCAAAGAGGAAGATTTTGCTCTTGCCAGCCTATTGAAAGaagaattagaactagtagacTGTAATGACTTGAAAACCCTCACTAAATCAATTAAGAAGAAACTCAAAAAGAAGGAAAGAAAtgaaaaaactaagaaaataagtaaaaagtgTAATGGTCGCCTGAAGACGACTATTTCTGATAATGatcaCTCAAACTATATTAGACTGGTAATAACGGAGAAGCAATGTAAGATGGAAAGAAAGAAGAGAATGCAGGAGGAGCCCTATTTGGGTAGCACTTATAAATGTGAAGACTGTATCAAGGGATTCTCACATAAGGAAGCATTTTACAAGCATATGATTTCACACAGTTTGAGTTGTGGAAAATTTTGGTGCCCCATTTGCAAGCAGCGGTTTCAATCGCCGGCAAAACTCCGTAACCATAAGCGATATCATTTTATCCGCTACAAATGCCTTGACTGCGGGGTGATGAGAGTCTGTCTGAACTCTATAAAGGAACACTACGCAAATAATCACAGTAGTTATGGaagtgtttttaaatgtacacaTTGCCCTAAAGTTTTCAACAATAAAACGACGCATCGTAAGCACGAGACAAACACACATTCGCGCATAGGCAGAGTGGTCTGCGACGTTTGTAACAAGAGCTACGTTAACAAGGATTCCCTGCTCGCACATATACTGAGGAAACACCCACCAGATGGCGCCATGGACAAGTTTCGCAAGCGTCACGTGTGTGCGGTGTGCGGGTGTGTGTTCGCAACGCCCTCTCAGCTGAAGAGCCATGCACTGGTGCACTCTGAGCATCGCGATTACTACTGCGTCGAGTGTGATAGAAGATTCAAAACTGCCGCCGTTTTAAAGCAACATTTGAAGACGGCTACGCCTCATGTCAACTATATGGAATTACCACTCTCCTGTGAGCACTGCGAGAAGAGGTTCTCCATAAAACGGGATGTAGAACGACACATGAACAGAGTTCATCTCAACATAAAGCCGTTCACGTGCGACAAATGTGATAGGGCTTATGTAAACAGCTGGTCTCTCCGTGACCACCAGCGGTACAACCACGAGGGTGTGAAGCGGCCGCTCCGATACCCCTGCGCGATGTGTGATAAAATGTTTGATcgCAGTTCCATCTTAAAGTCCCACGTGCGCACGCACACCGGGGAGCGCCCTTACCACTGCACACAATGCCCTGCGCAGTTCGCACAGGGCTCCGCACTGGGCACTCACGTGAAACTGGTCCACTTAAAGCTGACGAGAGACGGGCGGCCTAAGCAGGCCTGCATGAAATGA
- Protein Sequence
- MEVTENNQCCFGCLSTEDEFHLQEFSLQCEPLKTIFQVDVIVLCTVCKRIAQHADLFIQNVQSNQILLQNFHNDLSALQTICPQVQPCISLAHAPLPYLELPGTGTEECCIVVGPEQKIKMEPKEEFDQLDGEFIDGSDDFQDPYVKEEDFALASLLKEELELVDCNDLKTLTKSIKKKLKKKERNEKTKKISKKCNGRLKTTISDNDHSNYIRLVITEKQCKMERKKRMQEEPYLGSTYKCEDCIKGFSHKEAFYKHMISHSLSCGKFWCPICKQRFQSPAKLRNHKRYHFIRYKCLDCGVMRVCLNSIKEHYANNHSSYGSVFKCTHCPKVFNNKTTHRKHETNTHSRIGRVVCDVCNKSYVNKDSLLAHILRKHPPDGAMDKFRKRHVCAVCGCVFATPSQLKSHALVHSEHRDYYCVECDRRFKTAAVLKQHLKTATPHVNYMELPLSCEHCEKRFSIKRDVERHMNRVHLNIKPFTCDKCDRAYVNSWSLRDHQRYNHEGVKRPLRYPCAMCDKMFDRSSILKSHVRTHTGERPYHCTQCPAQFAQGSALGTHVKLVHLKLTRDGRPKQACMK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00703300;
- 90% Identity
- -
- 80% Identity
- -