Eint023943.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eupithecia inturbata
Gene Symbol
Btbd7
Assembly
GCA_963662085.1
Location
OY759204.1:1928032-1953129[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 1.5e-08 4.8e-06 27.3 0.0 6 57 132 187 129 227 0.74
2 4 3.3e-08 1.1e-05 26.2 0.0 22 79 307 365 299 373 0.83
3 4 0.26 87 4.0 0.0 81 108 405 432 398 434 0.85
4 4 7.2 2.4e+03 -0.7 0.0 28 44 639 655 635 669 0.80

Sequence Information

Coding Sequence
ATGAGTCGGCTGCTGTGCTGTCTGCGCGGGCGCCGACGAGACATGGGCGCCGCGCTCTCGCATCCCcagGAGGGAGAGGCGTCCGAGGTGGTCGCGCCTCCCACTATGGCGGATGTCATACGGGAGCGTAAGAAAAAGGCAGGAGGCGCGAGCCTCGGGACTCTGCGGCGAAGGATCGCGAACGCGGCTCGGCGGCCGCGGGATAACAGACCTGATAGAGGTTGCGAGCATGCTCGTTTTATCCGGTCCGTAGTGTCCTCCTGGCGTCTGGCGGAGGTTTTCGTGCTATGCGAAGAGCTAGAGGCAGGCTCAGCGCTGCGTGACCTCAGCACGCAGGCCGACCTAGCTCGCGAGCCCGCGCCCGCGCTTCACACGCAACTGCCCATAGCTCGGCAGGAGAGATGGTGGTGCGACGTGGAGCTGGTAGGCGGGTCAGGTGCGGGTTCGTGGTCCACGCACGCGCACCGAGCGATCCTGGCGGCGCGATCCGCTTACTTTCGGGACCTTTTCCATAGATATCCACCTACGCAGTTTGTCTCCTGCGTCAGAATACCACTAGAGGGCGTCTGCAGTACAATGACGTTAGCGGAATGCGAAGCGTGTCTGCACGCACTGTACAGCGGGCAACCACTCACGGCGAGAGCAATCACCCAAGGCAACCACGCTACTCACAAATATGACAACGAGAACCAAGAGGCTGAACTGGACATTATAAATGGTGATAGTAATCCCCGTAACAACACCTGTACTTGCACCAACATCATCCCCCCGCGGATAGCAGCCGCCATCGACGCCACCACCTGCTCTGTACAGACATCTATGCACTATCTACTGGACTCTGGTGAAATGGCAGACACTCGGCTAGTATTTAGACTAGAGAACGGCTGCGGTTCCGCCTACGGCTTCCGGACGGCTTTGGAGCTGCCCTGCCATAGAGTTGTACTGGCTGCTAGGTCGAGGTTCTTCAAGTCCCTATTGTCTCGCCGAGGCGCTTCCAGCACTTCAGGCGCTGTATGCGTCGACGAGACAGTACTGCCGAGGAGATATGCTAGAGCATTGCTACACGCCGCCTACACCGACCAGATTGATCTCAGTTTGATTGGAAGAAATACATCGTCACCGCCCTCAACCAACAGCGGGAGTACTTCAGCTTGGACAGGAGTGGGCAGGAGTAGCAACAACGCTTCTCGGCCTACAAACTGCGCCATGTTGGATGACGCCTTCCAGTTGTATGAGATAGCCAGGTTTCTAGAGATGCCAATAGTGGTGCAAGGCTGCGAAGATTCTATTGTGGAGGCCCTCACTCCGGAAACACTGCACCATGTGCTGCGctgggccgccgcgccgcacgccAGCCAGTGGGTGCTGAGACAAGCAATGCGCTACCTCCTCGACGAATTCACGCAAATAATGTCACACTCAAACGCGTGTCGCATCCCCCGAGCAGCGCTCACTCAAGCATTGGCCAGCGACCACCTGCAGGCGTCGGAGCAGCAGATATTGCGAGCCATAGTCAAGTGGAGCGCCGACCAGCCGCCCCCAAGAGAACCAAACGTGGTCTGGCACACGGCGCACTCTGTGTCACgacgcggcgcgcggcggcgctccAACTCCGACGCGGCGCTCCGAGAGACGCTAGCGTCGTTGGTGCCTTTAGTGCGCACCGAGCATCTGCCGGCTGACTGTATGACGTTACATCAGTTGGTCCGTCGAGGCATCATCCCCTCCCCGCCGCCGCCCGCTGAAGAAGGCTCGACGGCGCACGCGTGGCTCGGACGGGGGTCTTACAGACCTGCGCGCTGCTTTCTACCTTATTTAGATGAGATTAAGGCTTTACTAGAGGACCAAGCGGTACCGGAAGCAGAACTGGCGCGAGCGAGACGCGCGCGGTACCTGCACCGGATACCGGACACGTTGTATATGGTGAGTCATTCACAATACTTTTATACGTGTCTTTGTGTCCAATACGGCGCCAGCCCTCTTCAAGAGTCAAGGACTTACCGCCGAATACTAATAAGCAACTCTTATAATATGTGA
Protein Sequence
MSRLLCCLRGRRRDMGAALSHPQEGEASEVVAPPTMADVIRERKKKAGGASLGTLRRRIANAARRPRDNRPDRGCEHARFIRSVVSSWRLAEVFVLCEELEAGSALRDLSTQADLAREPAPALHTQLPIARQERWWCDVELVGGSGAGSWSTHAHRAILAARSAYFRDLFHRYPPTQFVSCVRIPLEGVCSTMTLAECEACLHALYSGQPLTARAITQGNHATHKYDNENQEAELDIINGDSNPRNNTCTCTNIIPPRIAAAIDATTCSVQTSMHYLLDSGEMADTRLVFRLENGCGSAYGFRTALELPCHRVVLAARSRFFKSLLSRRGASSTSGAVCVDETVLPRRYARALLHAAYTDQIDLSLIGRNTSSPPSTNSGSTSAWTGVGRSSNNASRPTNCAMLDDAFQLYEIARFLEMPIVVQGCEDSIVEALTPETLHHVLRWAAAPHASQWVLRQAMRYLLDEFTQIMSHSNACRIPRAALTQALASDHLQASEQQILRAIVKWSADQPPPREPNVVWHTAHSVSRRGARRRSNSDAALRETLASLVPLVRTEHLPADCMTLHQLVRRGIIPSPPPPAEEGSTAHAWLGRGSYRPARCFLPYLDEIKALLEDQAVPEAELARARRARYLHRIPDTLYMVSHSQYFYTCLCVQYGASPLQESRTYRRILISNSYNM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00699403;
90% Identity
iTF_00699403;
80% Identity
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