Eint020867.1
Basic Information
- Insect
- Eupithecia inturbata
- Gene Symbol
- -
- Assembly
- GCA_963662085.1
- Location
- OY759198.1:7264177-7264671[+]
Transcription Factor Domain
- TF Family
- Fork_head
- Domain
- Fork_head domain
- PFAM
- PF00250
- TF Group
- Helix-turn-helix
- Description
- The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.11 1.3e+02 3.4 0.0 13 38 14 39 8 41 0.77 2 9 0.013 15 6.4 0.1 9 39 23 53 17 60 0.71 3 9 0.017 20 6.0 0.1 9 38 36 65 33 71 0.68 4 9 0.021 24 5.7 0.1 9 38 49 78 45 82 0.73 5 9 0.02 23 5.8 0.1 9 38 62 91 57 95 0.73 6 9 0.013 15 6.4 0.0 9 39 75 105 70 113 0.70 7 9 0.02 23 5.8 0.1 9 38 88 117 83 121 0.73 8 9 0.01 12 6.7 0.1 9 40 101 132 97 146 0.69 9 9 0.68 7.9e+02 0.9 0.0 9 26 127 144 123 156 0.78
Sequence Information
- Coding Sequence
- ATGGATTGGTTTGTGCCGCACATGCTGCAGCTGCGGCAAAATGAAATAACCGCTTCTCCGCACAGGCAGTTGACGTACAATGAAATAACCGCTTCTCCGCACAGGCAGTTGACGTACAATGAAATAACCGCTTCTCCGCACAGGCAGTTGACGTACAATGAAATAACCGCTTCTCCGCACAGGCAGTTGACGTACAATGAAATAACCGCTTCTCCGCACAGGCAGTTGACGTACAATGAAATAACCGCTTCTCCGCACAGGCAGTTGACGTACAATGAAATAACCGCTTCTCCGCACAGGCAGTTGACGTACAATGAAATAACCGCTTCTCCGCACAGGCAGTTGACGTACAATGAAATAACCGCTTCTCCGCACAGGCAGTTGACGTACAATGAAATAACCGCTTCTCCGCACAGGCAGTTGACGTTGCGTAGTGATGCTATGTTTTGCCGCATACGCAGCGTGGTGCGTTGCGaacaagagaccaaggcttaa
- Protein Sequence
- MDWFVPHMLQLRQNEITASPHRQLTYNEITASPHRQLTYNEITASPHRQLTYNEITASPHRQLTYNEITASPHRQLTYNEITASPHRQLTYNEITASPHRQLTYNEITASPHRQLTYNEITASPHRQLTYNEITASPHRQLTLRSDAMFCRIRSVVRCEQETKA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -