Basic Information

Insect: Eupithecia insigniata
Gene Symbol: zfh1
Assembly: GCA_947859395.1
Location: OX402021.1:598787-605545[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 37 0.0037 0.24 12.3 1.0 2 21 159 178 158 179 0.95

2 37 0.28 19 6.4 0.4 1 23 212 235 212 235 0.94

3 37 0.15 9.7 7.3 0.5 2 23 241 262 240 262 0.96

4 37 0.047 3.1 8.9 1.4 2 21 266 285 266 286 0.93

5 37 0.0014 0.094 13.6 0.9 2 23 324 346 323 346 0.95

6 37 0.18 12 7.0 0.6 3 23 354 373 353 373 0.95

7 37 0.0031 0.2 12.6 1.4 1 23 378 400 378 400 0.98

8 37 0.004 0.26 12.2 3.7 1 23 406 429 406 429 0.97

9 37 0.0014 0.089 13.7 0.1 1 23 438 461 438 461 0.96

10 37 0.54 36 5.5 0.6 1 17 471 487 471 488 0.93

11 37 0.002 0.13 13.2 0.1 1 20 601 620 601 622 0.95

12 37 1.1 72 4.6 1.3 1 23 652 674 652 674 0.96

13 37 0.0078 0.51 11.3 0.4 2 23 679 701 678 701 0.95

14 37 0.093 6.1 7.9 5.1 3 21 706 724 705 725 0.93

15 37 0.0017 0.11 13.4 1.6 1 23 734 757 734 757 0.96

16 37 0.01 0.67 10.9 4.5 1 23 763 785 763 785 0.97

17 37 0.00058 0.038 14.9 0.6 1 23 792 815 792 815 0.98

18 37 1.8 1.2e+02 3.9 4.4 2 23 829 852 828 852 0.90

19 37 0.023 1.5 9.8 0.2 2 21 953 972 952 973 0.94

20 37 0.016 1.1 10.3 1.6 1 23 1003 1026 1003 1026 0.93

21 37 0.00074 0.049 14.5 1.4 3 23 1033 1053 1031 1053 0.97

22 37 2 1.3e+02 3.7 2.5 3 20 1058 1075 1056 1077 0.90

23 37 0.0005 0.033 15.1 0.5 1 23 1089 1112 1089 1112 0.94

24 37 4.9e-05 0.0032 18.2 2.0 1 23 1118 1140 1118 1140 0.98

25 37 0.12 7.6 7.6 1.2 5 23 1150 1168 1148 1168 0.97

26 37 0.022 1.4 9.9 1.2 1 23 1174 1197 1174 1197 0.96

27 37 0.023 1.5 9.9 0.2 3 23 1207 1228 1206 1228 0.96

28 37 0.00028 0.019 15.8 0.3 2 21 1350 1369 1349 1370 0.94

29 37 6.5 4.3e+02 2.1 0.0 3 23 1377 1398 1375 1398 0.93

30 37 0.03 2 9.5 0.0 3 23 1405 1426 1404 1426 0.96

31 37 0.0007 0.046 14.6 0.3 3 23 1433 1453 1431 1453 0.95

32 37 0.13 8.4 7.5 2.5 2 20 1457 1475 1456 1477 0.92

33 37 2.4e-05 0.0016 19.2 0.3 1 23 1501 1524 1501 1524 0.95

34 37 0.0011 0.07 14.0 2.2 1 23 1530 1552 1530 1552 0.96

35 37 0.066 4.3 8.4 0.2 1 23 1558 1580 1558 1580 0.98

36 37 0.021 1.4 9.9 0.1 1 23 1586 1609 1586 1609 0.94

37 37 0.0004 0.026 15.4 1.4 1 23 1615 1638 1615 1638 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	37	0.0037	0.24	12.3	1.0	2	21	159	178	158	179	0.95
2	37	0.28	19	6.4	0.4	1	23	212	235	212	235	0.94
3	37	0.15	9.7	7.3	0.5	2	23	241	262	240	262	0.96
4	37	0.047	3.1	8.9	1.4	2	21	266	285	266	286	0.93
5	37	0.0014	0.094	13.6	0.9	2	23	324	346	323	346	0.95
6	37	0.18	12	7.0	0.6	3	23	354	373	353	373	0.95
7	37	0.0031	0.2	12.6	1.4	1	23	378	400	378	400	0.98
8	37	0.004	0.26	12.2	3.7	1	23	406	429	406	429	0.97
9	37	0.0014	0.089	13.7	0.1	1	23	438	461	438	461	0.96
10	37	0.54	36	5.5	0.6	1	17	471	487	471	488	0.93
11	37	0.002	0.13	13.2	0.1	1	20	601	620	601	622	0.95
12	37	1.1	72	4.6	1.3	1	23	652	674	652	674	0.96
13	37	0.0078	0.51	11.3	0.4	2	23	679	701	678	701	0.95
14	37	0.093	6.1	7.9	5.1	3	21	706	724	705	725	0.93
15	37	0.0017	0.11	13.4	1.6	1	23	734	757	734	757	0.96
16	37	0.01	0.67	10.9	4.5	1	23	763	785	763	785	0.97
17	37	0.00058	0.038	14.9	0.6	1	23	792	815	792	815	0.98
18	37	1.8	1.2e+02	3.9	4.4	2	23	829	852	828	852	0.90
19	37	0.023	1.5	9.8	0.2	2	21	953	972	952	973	0.94
20	37	0.016	1.1	10.3	1.6	1	23	1003	1026	1003	1026	0.93
21	37	0.00074	0.049	14.5	1.4	3	23	1033	1053	1031	1053	0.97
22	37	2	1.3e+02	3.7	2.5	3	20	1058	1075	1056	1077	0.90
23	37	0.0005	0.033	15.1	0.5	1	23	1089	1112	1089	1112	0.94
24	37	4.9e-05	0.0032	18.2	2.0	1	23	1118	1140	1118	1140	0.98
25	37	0.12	7.6	7.6	1.2	5	23	1150	1168	1148	1168	0.97
26	37	0.022	1.4	9.9	1.2	1	23	1174	1197	1174	1197	0.96
27	37	0.023	1.5	9.9	0.2	3	23	1207	1228	1206	1228	0.96
28	37	0.00028	0.019	15.8	0.3	2	21	1350	1369	1349	1370	0.94
29	37	6.5	4.3e+02	2.1	0.0	3	23	1377	1398	1375	1398	0.93
30	37	0.03	2	9.5	0.0	3	23	1405	1426	1404	1426	0.96
31	37	0.0007	0.046	14.6	0.3	3	23	1433	1453	1431	1453	0.95
32	37	0.13	8.4	7.5	2.5	2	20	1457	1475	1456	1477	0.92
33	37	2.4e-05	0.0016	19.2	0.3	1	23	1501	1524	1501	1524	0.95
34	37	0.0011	0.07	14.0	2.2	1	23	1530	1552	1530	1552	0.96
35	37	0.066	4.3	8.4	0.2	1	23	1558	1580	1558	1580	0.98
36	37	0.021	1.4	9.9	0.1	1	23	1586	1609	1586	1609	0.94
37	37	0.0004	0.026	15.4	1.4	1	23	1615	1638	1615	1638	0.96

Sequence Information

Coding Sequence: ATGAGTCGCCAAGTGGACGTAAAGGCTTTGATATCACATATCGTGAAAGGTGATGGCTTAGACAAATGCAGAGTTTGCATGGGAGATACATCACAAGGACAAGTCCACCTCTCTGACACAGTAATGATGGACGGAGACAAAGCTGTTACGCTCTCGGAGCTTCTTGAAGTCATCACAGGAGTCGAGGTGGAGTTGGAAGAAGAGCTACCACCTTCATTATGCCTAACTTGCTCCGTTGCTGCCTTCGAAGCAGCTGAATTCAAGACCCTGGTCCAAAGGGCCCAGCGGCAGTGGAACAGCACCGTCAACTTGTTAGACCACATTCCTGACCACAAATACGCGCTGACTAGTCGTAAGATCCTCGCAGTTCTATCCAATAACTGTATAGAGATTTGTGATGAAGGAATAAAACCACCTGTTGAGAAACCAAGAGAGAATCCAATACTGAAAAGACCGGGAAAGTTACAAGAATGTCAATGCCCAACTTGTGGTAATAAGTTTCAGTATGCAGTGCAGCTTAATAAGCATTTGAGGGACTCTGTGGACCTACTCCGGGCTTGTCACATCTGTGCTGAAGTTATGAGTAGAAGCAAACTGTTAAAACATGTCAAAGAAGAGCATAATATAAAAACATACCCCTGTAAGAAATGCCCAGCTATATTAACTAATTCCAAACTGTTTTTCGACCATAATTTAAAAGCTCATGCAAAAGGGAGTATTAAATGTGTAGATTGTAGCTATACATTCCTGACCCCACAAGCGATGAACGCTCATCAACACATACATACGCAAAGATCCTGTCCAAATTGCGACAAAGTCTTTCAAAACCGACCATGCTATTCCTACCACATTAAAAAATGCTGCAAACTAGACCTTAAACACAAGAGCAAACAAGTACCAGTAACCTTACAGAACAAAGAAAACAAAAAGGTTAAAATGGGAAAGCGAGGCAGCATTAACCATAAATGCATCTGTGACTATTGCAATAAAACATATGCTGCCAAAAAGTTCTTGACCGCTCACATACAAATAGTTCACTTAAAGAATACACACAGACCTTGTGTTTACTGCGGCAAGCAGTTTGCGGCTGCTCACATGTCAACACATTTAAAGAGTCATAAGAAATCCAGCTTTAAGTGTGAACATTGTGGGGTAGTGCTTAAGTCTAAACTAGGTTTCATGCAGCATTTAAGACTTCACACTGGAGAGAGACCTTACAAATGCAGCCTCTGTGGAGAACACTTCTCATCTTCATCGAGGATGTCAGAGCACAAACGGAACAAACACTTTAAATCGCAAATAGTCCTAAAATACGTCTGCACAATTTGCCCAGCTAAGTTCAGACTGCCAGGTAAACTTAAAATGCATATAGATAAGGTCCATACTTGCAATGGAACGGAAGAAGTCAGTTATAAATGCGAGTTATGCCGTGAGATGTTTGACAGCTGTCAAAATCTGATGGAAGATTGCAATGCCTGCAACACTCCGCAACAGCTGTGCCAGCAATGTATATCCGATATCACCGCCTTTCTACCATTCCTGAGACTCTGCAAACAATCCGCCGAACATTGGAACTTCTTATCCGAGAATTTGATCAACCTTTCTACCCAGAAGACTTTTAACACAGCTTTCATCTTTGTTAACGAAAAAAGTGACAAAGTTACCACTGTGTACGAGAAAAGGGATAGAAGCAAGAATAAATTGTGGCATGTCGTGACGAAGCGGATTAACCAACTAGAGTCTGCAAGACGGACACGAGAGGCCAGCGACAATGAACCAACTAAGCCTGGAAAATTTCTCTACACTTGCGTAGAGTGCGGCGCGAAGTTTAGCCGGTTGGACAACATAAATAACCACTTAGCGAACCAGAAAAAGCGTTTCTGTTCTCATTGCCACGAGATTATCGATCTAAAAGCTTTTGGAGTGCATCTTGAGTCGCATTCAATCCCTATCTATACCTGCAAGATCTGTTCCTTACCTTTAGAGTGTAAAGAACAGTTGATAAAACACAAAAGTGTCCATAAAGGTAGAATCATGTGCGGGGAATGCAAAATGGGCTTTCCATCAGCGCACTACCTAAATATTCACGTCAATAGAAAGCATGAGCGAGCTTCCTGCGTCAAATGTAATAAAAAGTTTTCCAATCGCATATGTTTTCAGAAGCATCGAAACAAATGCACATCAAGGAAGCCAGAGAAATATATTTGTGATCACTGCTCAAAGGAGTTCAGTGAGAAAGGCAATATTAAGTTGCACATTTATAAAATGCATTCAAAGATCTTTTCCCATCAATGCGAGGTGTGCGGAAGGAATTTTAACAGTGCATGTCACTTGGACGAACATAAAGAATCCCACAATGTGGTACTAGATAGATATGTCTGCCCGTTTTGTGGTGGGCAGTATAGTTCTTCGGGAGGCTATCGAAAGCACTTGAGACGTAAACATTATAGCACTAATCCCGAACTGAAGATGGATATGAAATGCACGTGTGATATCTGTGATATTGAGTTTATAAGTTTTAAGAACCACCAGAATCATTTGAGATCTAAGAAACATAAAGATAAAGTAGACGACGGCCTCGCGCTCCCGCCAGGGCTCTGCGGCGTCTGTGCAGGCGACGTTATATCCGCCGCCAAATTCAGACAACTTACCGATAAGTCCGCGCAATGCTGGAACGAAGCGGCTCAATACCTCTCACAAATAGACAGTGAGGGCAAAGACACCAAAACACTGCTTTACGTCTACGAAGAACACACTCTGATATTCTACGAGAAACGGGCCAAGAGTGTTAAATCTGCGGTCACAGCTCTCGCTAATTTCGAGAAGGAAACAACGGTCAATAAAAAGCATCCTACTTCATGCCCTTTCTGCGATAAACGGGTGATTTCTGTTCAGAATCTTAACCAGCATCTTAAAAACAGCTCTAAAAGAATGTGCATTTGCGGTTGGCTTATGGATAAATCAGAAATCTGTAAACACTTGCGAGATACACACAAGATCGAGGTCTTCGAATGCAGTGTATGTCATGAGCAGTTTCAGAGTAATGAGGGTCTAAAGTGGCATAGCACGAAATCCCACGGTCCTAAGTCGTTCGGTTGCGAGCATTGCGGACGTAGTTACAGAAACGAGAGAGCCTTGCGGGCCCATTCCTACACCCATACTTTGTTGGACTGCTCCGCGTGCGGGAGAACTTTCGAGAACATCCGCTGTTATCGTCACCACAAAACTACATGCAAATCTAAACAAAAAAATGACTTCAGTATCTTTCAGTGTAATGACTGCGGACAACAATATGAAAAGAAAGGATCTCTTCGAATACACGTGATACAGAAGCATTTGAATGTCCTGCCTTACGTTTGTCAGATCTGTGGCAAGCAAACTTCAACCTTAAGCCATTTGAAATCTCACTCTAAAGTTCACGAGGCAGATAGGAAGACTTTAGAATGCCACTGCGGGGCTAAATTCCGGACTGAATTAGGGTACCGTTTACATATGAGAATCCACAGCGGTTTGAGACCTTTTAAATGTGAGGAGTGCGAGGAGACTTTTATATCGGCGTCTAGACGCTCCGATCATTATAAAAGACGACATAAGAATGTGAAAGATATGGCGCATGGTTGCGAGCAGTGCTTGGCTCGGTTCATCAGGCCTTGGGAACTGAAGAAACATTACAAACTCTCGCATAGTTCGATAGTGGATGTGCAGCCAGCGAAGCGACAAAGGTCGACTATTAAAGAAGAGACCTTCTGTCCGGGCGGTGTTTGCGTAGCTTGCGCAAGCGCAGCGCTGGCCGCGGAAGAGTTTCGTCTATTCGTCCGCAACGCCGTCTCTCTCTGGCGCCGCGCCATCGTCAACCTCTCCCAACTACCCTACGACGCATCCGACAACGCCAAATCCGTTTGCGCGGTCGTTTCCCCCAACATTACTGTCGACACACACAGTGATTTCGACGCCGGCGATGCGACTGAAGTAATTGATAAATTGCAGTCGAAGTTGATTAAAAAACACGAGAGAAAACCCCGCGTTCTCCGAACCGGACCCACGGTAACCTGCCCTGATTGCAACAAGCAGTTCTCAGGTCCCCATTTATTGCAAACGCATCTACAGAACAGCGATAGGAAAGACGCTTGTGGAATATGCGGCGCCGTTGTTACTATAGGTGCTGGGTTGAAATATCATCTGACAACAGTGCACAGAGAACCTGCTATCCTGTGCAAAGAATGCCCGACCGTTGTGATCACAGAAGCTGAGCTCAAAGCACACGAGAGATTAGCTCATAAACCTGGGGCCCTAAACTGCGGCGCTTGCGGCAGGACTTTTACCCGCAAAGGATCCTACGATAGCCATATCCAAATGCACGTCGTCTTGACCTGCAGACTGTGCGGTAGCCAATTCTCTAATAGAAGCTGCTTCCGCCAACACAGATCCGTTTGCGAGCCCAACGCAAAACCTAAATCCATCCCCCGCATACGTCGTTCCAACAACCGCGACCCCGGTCAATACGTATGCGATTACTGTCAAAAGATGTACAGCTCTCGGCCGCAATTGAAGAACCATATACTCTGGATCCATTTGGACCACAGACCGCACCAATGCTCCTTTTGCGGGAAGCGATTCTACACATCAGCGAGGTTGAACGAGCATACCGTTGTCCATACGAGAGCTAGGAACTTTGAGTGTGATCTATGTGACGCGAAACTAGTGTCTAAAAGTGCTGCGATTTACCACAGACGAAGGCATACTGGGGAGAAGCCCTACGTTTGCGACGACTGTGGAGCAGCGTTTATCTCCTCATCAAGGAGGCTGGAACACGCTAAACGGAAACATAACAAAGGGATCCGGTTCAAGTGTACAGAGTGTACTTCTAGCTTCGTACGAAGACGGGAGCTTGAGAAACATGTGGAGAAAAATCATAAAGGCACTGTTAAGTCTGAGGTATTCAAAAGTGACTTCAAGGTCGAAAAACTTGAAGTAATTTCTTAG
Protein Sequence: MSRQVDVKALISHIVKGDGLDKCRVCMGDTSQGQVHLSDTVMMDGDKAVTLSELLEVITGVEVELEEELPPSLCLTCSVAAFEAAEFKTLVQRAQRQWNSTVNLLDHIPDHKYALTSRKILAVLSNNCIEICDEGIKPPVEKPRENPILKRPGKLQECQCPTCGNKFQYAVQLNKHLRDSVDLLRACHICAEVMSRSKLLKHVKEEHNIKTYPCKKCPAILTNSKLFFDHNLKAHAKGSIKCVDCSYTFLTPQAMNAHQHIHTQRSCPNCDKVFQNRPCYSYHIKKCCKLDLKHKSKQVPVTLQNKENKKVKMGKRGSINHKCICDYCNKTYAAKKFLTAHIQIVHLKNTHRPCVYCGKQFAAAHMSTHLKSHKKSSFKCEHCGVVLKSKLGFMQHLRLHTGERPYKCSLCGEHFSSSSRMSEHKRNKHFKSQIVLKYVCTICPAKFRLPGKLKMHIDKVHTCNGTEEVSYKCELCREMFDSCQNLMEDCNACNTPQQLCQQCISDITAFLPFLRLCKQSAEHWNFLSENLINLSTQKTFNTAFIFVNEKSDKVTTVYEKRDRSKNKLWHVVTKRINQLESARRTREASDNEPTKPGKFLYTCVECGAKFSRLDNINNHLANQKKRFCSHCHEIIDLKAFGVHLESHSIPIYTCKICSLPLECKEQLIKHKSVHKGRIMCGECKMGFPSAHYLNIHVNRKHERASCVKCNKKFSNRICFQKHRNKCTSRKPEKYICDHCSKEFSEKGNIKLHIYKMHSKIFSHQCEVCGRNFNSACHLDEHKESHNVVLDRYVCPFCGGQYSSSGGYRKHLRRKHYSTNPELKMDMKCTCDICDIEFISFKNHQNHLRSKKHKDKVDDGLALPPGLCGVCAGDVISAAKFRQLTDKSAQCWNEAAQYLSQIDSEGKDTKTLLYVYEEHTLIFYEKRAKSVKSAVTALANFEKETTVNKKHPTSCPFCDKRVISVQNLNQHLKNSSKRMCICGWLMDKSEICKHLRDTHKIEVFECSVCHEQFQSNEGLKWHSTKSHGPKSFGCEHCGRSYRNERALRAHSYTHTLLDCSACGRTFENIRCYRHHKTTCKSKQKNDFSIFQCNDCGQQYEKKGSLRIHVIQKHLNVLPYVCQICGKQTSTLSHLKSHSKVHEADRKTLECHCGAKFRTELGYRLHMRIHSGLRPFKCEECEETFISASRRSDHYKRRHKNVKDMAHGCEQCLARFIRPWELKKHYKLSHSSIVDVQPAKRQRSTIKEETFCPGGVCVACASAALAAEEFRLFVRNAVSLWRRAIVNLSQLPYDASDNAKSVCAVVSPNITVDTHSDFDAGDATEVIDKLQSKLIKKHERKPRVLRTGPTVTCPDCNKQFSGPHLLQTHLQNSDRKDACGICGAVVTIGAGLKYHLTTVHREPAILCKECPTVVITEAELKAHERLAHKPGALNCGACGRTFTRKGSYDSHIQMHVVLTCRLCGSQFSNRSCFRQHRSVCEPNAKPKSIPRIRRSNNRDPGQYVCDYCQKMYSSRPQLKNHILWIHLDHRPHQCSFCGKRFYTSARLNEHTVVHTRARNFECDLCDAKLVSKSAAIYHRRRHTGEKPYVCDDCGAAFISSSRRLEHAKRKHNKGIRFKCTECTSSFVRRRELEKHVEKNHKGTVKSEVFKSDFKVEKLEVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00698500; iTF_00696644;
90% Identity: -
80% Identity: -