Basic Information

Insect: Eupithecia abbreviata
Gene Symbol: ZEB2
Assembly: GCA_943735975.1
Location: CALSER010000167.1:2704-12747[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 37 0.0015 0.09 13.5 0.8 2 21 159 178 158 179 0.95

2 37 8.4 5e+02 1.7 0.4 3 23 187 207 186 207 0.89

3 37 0.17 10 7.1 0.1 1 23 212 235 212 235 0.94

4 37 1.4 83 4.2 0.3 2 23 241 262 240 262 0.94

5 37 0.093 5.5 7.9 3.7 3 21 267 285 266 286 0.93

6 37 0.0037 0.22 12.3 0.8 2 23 324 346 323 346 0.95

7 37 0.17 10 7.0 0.6 3 23 354 373 353 373 0.95

8 37 0.0097 0.57 11.0 1.5 1 23 378 400 378 400 0.98

9 37 0.0038 0.22 12.3 3.7 1 23 406 429 406 429 0.97

10 37 0.0027 0.16 12.7 0.4 2 23 439 461 439 461 0.95

11 37 1.3 77 4.3 0.6 1 16 471 486 471 488 0.90

12 37 0.0026 0.16 12.8 0.0 1 20 598 617 598 619 0.94

13 37 0.89 53 4.8 3.8 1 23 649 671 649 671 0.97

14 37 0.0013 0.078 13.7 1.4 2 23 676 698 675 698 0.95

15 37 0.16 9.5 7.1 4.9 3 21 703 721 702 722 0.92

16 37 0.003 0.18 12.6 3.1 1 23 731 754 731 754 0.97

17 37 0.0091 0.53 11.1 5.6 1 23 760 782 760 782 0.98

18 37 0.0013 0.077 13.7 1.7 1 23 789 812 789 812 0.97

19 37 0.013 0.74 10.6 0.1 2 21 926 945 925 946 0.93

20 37 0.034 2 9.3 1.6 1 23 976 999 976 999 0.94

21 37 0.0006 0.036 14.8 0.9 3 23 1006 1026 1004 1026 0.98

22 37 1.9 1.1e+02 3.8 5.5 1 20 1029 1048 1029 1050 0.91

23 37 0.00044 0.026 15.2 1.3 1 23 1062 1085 1062 1085 0.94

24 37 0.00022 0.013 16.2 1.7 1 23 1091 1113 1091 1113 0.98

25 37 0.18 11 7.0 1.0 5 23 1123 1141 1121 1141 0.97

26 37 0.0025 0.15 12.8 0.9 1 23 1147 1170 1147 1170 0.98

27 37 0.022 1.3 9.9 0.2 3 23 1180 1201 1179 1201 0.96

28 37 0.00073 0.043 14.5 0.1 2 21 1324 1343 1323 1344 0.94

29 37 2 1.2e+02 3.7 0.0 3 23 1351 1372 1349 1372 0.95

30 37 0.15 8.9 7.2 0.0 3 23 1379 1400 1378 1400 0.92

31 37 6.4e-05 0.0037 17.9 0.6 2 23 1406 1427 1405 1427 0.95

32 37 0.038 2.2 9.1 3.2 2 20 1431 1449 1430 1450 0.94

33 37 2.3e-05 0.0013 19.3 0.3 1 23 1475 1498 1475 1498 0.95

34 37 0.001 0.061 14.0 2.2 1 23 1504 1526 1504 1526 0.96

35 37 0.063 3.7 8.4 0.2 1 23 1532 1554 1532 1554 0.98

36 37 0.037 2.2 9.2 0.1 1 23 1560 1583 1560 1583 0.94

37 37 0.00011 0.0063 17.1 2.0 1 23 1589 1611 1589 1612 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	37	0.0015	0.09	13.5	0.8	2	21	159	178	158	179	0.95
2	37	8.4	5e+02	1.7	0.4	3	23	187	207	186	207	0.89
3	37	0.17	10	7.1	0.1	1	23	212	235	212	235	0.94
4	37	1.4	83	4.2	0.3	2	23	241	262	240	262	0.94
5	37	0.093	5.5	7.9	3.7	3	21	267	285	266	286	0.93
6	37	0.0037	0.22	12.3	0.8	2	23	324	346	323	346	0.95
7	37	0.17	10	7.0	0.6	3	23	354	373	353	373	0.95
8	37	0.0097	0.57	11.0	1.5	1	23	378	400	378	400	0.98
9	37	0.0038	0.22	12.3	3.7	1	23	406	429	406	429	0.97
10	37	0.0027	0.16	12.7	0.4	2	23	439	461	439	461	0.95
11	37	1.3	77	4.3	0.6	1	16	471	486	471	488	0.90
12	37	0.0026	0.16	12.8	0.0	1	20	598	617	598	619	0.94
13	37	0.89	53	4.8	3.8	1	23	649	671	649	671	0.97
14	37	0.0013	0.078	13.7	1.4	2	23	676	698	675	698	0.95
15	37	0.16	9.5	7.1	4.9	3	21	703	721	702	722	0.92
16	37	0.003	0.18	12.6	3.1	1	23	731	754	731	754	0.97
17	37	0.0091	0.53	11.1	5.6	1	23	760	782	760	782	0.98
18	37	0.0013	0.077	13.7	1.7	1	23	789	812	789	812	0.97
19	37	0.013	0.74	10.6	0.1	2	21	926	945	925	946	0.93
20	37	0.034	2	9.3	1.6	1	23	976	999	976	999	0.94
21	37	0.0006	0.036	14.8	0.9	3	23	1006	1026	1004	1026	0.98
22	37	1.9	1.1e+02	3.8	5.5	1	20	1029	1048	1029	1050	0.91
23	37	0.00044	0.026	15.2	1.3	1	23	1062	1085	1062	1085	0.94
24	37	0.00022	0.013	16.2	1.7	1	23	1091	1113	1091	1113	0.98
25	37	0.18	11	7.0	1.0	5	23	1123	1141	1121	1141	0.97
26	37	0.0025	0.15	12.8	0.9	1	23	1147	1170	1147	1170	0.98
27	37	0.022	1.3	9.9	0.2	3	23	1180	1201	1179	1201	0.96
28	37	0.00073	0.043	14.5	0.1	2	21	1324	1343	1323	1344	0.94
29	37	2	1.2e+02	3.7	0.0	3	23	1351	1372	1349	1372	0.95
30	37	0.15	8.9	7.2	0.0	3	23	1379	1400	1378	1400	0.92
31	37	6.4e-05	0.0037	17.9	0.6	2	23	1406	1427	1405	1427	0.95
32	37	0.038	2.2	9.1	3.2	2	20	1431	1449	1430	1450	0.94
33	37	2.3e-05	0.0013	19.3	0.3	1	23	1475	1498	1475	1498	0.95
34	37	0.001	0.061	14.0	2.2	1	23	1504	1526	1504	1526	0.96
35	37	0.063	3.7	8.4	0.2	1	23	1532	1554	1532	1554	0.98
36	37	0.037	2.2	9.2	0.1	1	23	1560	1583	1560	1583	0.94
37	37	0.00011	0.0063	17.1	2.0	1	23	1589	1611	1589	1612	0.96

Sequence Information

Coding Sequence: ATGAGTCGGCAAGTGGACGTAAAGGCTCTTATATCACATATCGTGAAAGGCGACGGCTTAGACAAATGCAGAGTTTGCATGGGAGATACATCACAAGGACAAGTCCACCTCACTGACACAGTAATGATGGACGGAGACAAAGCTGTTACGCTCTCAGAGCTTCTTGAAGTTATCACAGGTGTTGAGGTGGAGTTGGAAAATGCGCTACCATCCTCCTTATGCCTAACCTGCTCCGTAGCTGCCTTCGAGGCAGCCGAGTTCAAGACCCTGGTCCTAAGGGCGCAGCGGCAGTGGAACAGCACTGTCAACATGTTAAACCACATTCCTGATCATAAATACGCCCCAACTAGTCATAAGATCCTCGCAGTCCTATCCAATAACTATATTAAAATTTGTGACGAAGGAATAAAACCACCTGTTGAGAAGCCGAGAGACATTCCAATTCTGAAAAGACCGGGAAAGTTACAAGAATGTCAATGCCCAACTTGTGGGAACACGTTTCAGTATGCTGTGCAGCTTAATAAGCATTTGAGGGACTCCGTAGACTTGCTCCGGGCTTGTCACATCTGTGCTGAAGTCATGAGTAGAAGCAAACTGATAAAACATGTCAAAGAGGAGCATAATATAAAAACATACCCATGTAAGAAATGCCCAGCCATACTAACTAATGCCAAACTGTTATCTGATCATAATTTGAAAGCACATGCAAAAGGGAGTATTAAGTGTGTCGATTGTAGTTATACATTCCTAACACCACAAGCAATATACGCTCATCAACACATACATACTCAAAGATGCTGTCCAAACTGCGACAGAGTCTTTCGAAACCGACCATGTTATTCCTACCACATCAAAAAATGCTGCAAACTAGACCTTAAACACAAGAGCAAACATGTACCAGTAACCTTACAGAACAAAGAAAACAAAAAGGTTACAATGGGAAAGCGAGGCAGCATCAACCATAAATGCATCTGCGATTATTGTAATAAAACTTATGCTGCCAAAAAGTTCTTATCAGCTCATATACAGATAGTCCACTTGAAGAATACACACAGACCTTGTGTTTACTGCGGCAAGCAGTTTGCGGCTGCTCACATGTCCACACATTTAAAGAGTCATAAGAAATCAAGCTTTAAGTGTGACCATTGTGGGGTAGAGCTTAAGTCTAAACTAGGTTTCATGCAGCACTTAAGACTTCACACGGGAGAGCGACCTTACAAATGCAGTCTCTGCGGAGAACACTTCTCATCTTCATCGAGGATGTCAGAGCACAAACGGAACAAACACTTTAAATCTCAAATAGTCTTAAAAAACGTCTGCACAATTTGCTCGGCTAAGTTCAGACTGCCATCTAAACTTAAAATGCATATGGATAAGGTCCATAAATGCAATGGAATGGAAGAAGTCTGTTATAAATGCGAGTTATGCCGTGAGATGTTTGACAGCTGCCAAAGTCTGATGGAAGATGGCAACACTCCGCGACAGCTGTGCCAACAATGTATGTCCGATATCACCGCCTTTCTACCATTCCTGAGACTCTGCAAACAATCCGCCGCATATTGGAGCTTTCTATCCGAAAATTTGATCAACCTTTCTTCCCAGAAGACTTTTAACACAGCTTTCATCTTTGTCAACGATAAAATAGATAAAGTTACCAACGTGTTCGAGAAAAGGGATAGAAACAAGAATAAGTTGTGGCATGTCGTGACAAAGCGGATTAACCAGCTGGAGTCGGCGAGACGGACACTAGAGTCCGACGACAATGAACCAACGAAGCCGGGAAAGTTTCTCTACACTTGCGTAGAGTGCGGTGCGAAGTTTACCCGGTTGGAGAACATTAACAATCATTTAGCGAGCCAAAACAAGCGTTTCTGTGCTCATTGCGAGCAGATTATCGAGCTTAAAGCTTTTGGAGCGCATCTGGAGTCGCATTCAATCCCTTTCTATACCTGCAAGATGTGCTCTGTACCCTTTGAGTGTAAATACCAGTTTATAAAACACAAAAGTGTGCATCAAGGTAGAATCATGTGTGGGGAATGCAAGATCACCTTTCCCTCAGCGCATCACCTAAATATTCACGTTAACAGGAAGCATGAGCGCGCTTCATGCGTCAAATGTAATAAAAAGTTTTCTAATCGCATATGTTTTAACAAGCATCGAAGTAAATGCAAGTCTAGGATCTCTGAGAAGTATATTTGTGATCACTGTTCAAAGGAGTTCAGTGAGAAGGGGCATATTAAGCTGCACATTTATACAATGCATTCAAAGGTCTCGTCCCATCAATGCGAACTGTGCGGGAGAAAGTTTAACAGTGCGTGTCACTTGGACGAACATAAAGAAACCCATAATGTGATACCAGATAGATATGTCTGCCCATTTTGTGGCGGGCGCTATAGCTCCTCGGGAGGCTATCGAAAGCATTTGAGACATAAGCATTATAGAACTAATCCAGAACTGAAGATGGATATGATATGCACGTGCGATGTGGACGACGGGCCAGCGCTCCCGCCGGGGCTCTGCGGCGTCTGCGCAGGCGACGCTATATCTGCCGCTAAATTCAGAAAACTCACCGAAAAGTCTGCGAAATGCTGGAGCGAAGCCGCCCAATACCTCTCACGAATAGACAGCGAGAGCAACGACACGAAAACACTGCTTTACGTCCACGAAGAACACACTTTGATATTCTACGAGAAACGGGCCAAGAGTGCTAAATCTGCGGTCAAAGCTCTCGGAAACTACGAGAAGGCACCAACGTTCAATAGAAAGAACCCGATTTCATGCCCATTCTGCGGTAAGCGGGTGATTTCTGTGCAGAATCTTAACCAACATCTTCAAAACAGCTCGAAAGCAGTGTGTATTTGCGGTTCCCTTATGGAGAAATCGGAAATCTGTGAACACTTGCGAGAGATACACCAGATCGAGGTCTTCGAATGCAGCATCTGTCATGAGCAGTTTCAGAGTAATGAGGTTTTAAAGTGGCATAGCAGTAAATCCCACGGCTCTAAGTCGTTCGGTTGCGAGCATTGCGGACGTGGTTACAGAAACGAGAGAGCCTTGCGGGCCCATTACTACACCCACACTTTGTTCGACTGCTCCGCTTGCGGGAGAACTTTCGAGAACAGCCGATGTTACCACCACCACAAGACTACATGCAAAACTAAACATAACAATGATTTCAGTATCTTTGAGTGTCATGACTGCGGACAGAAATACGACAAGAAAGGATCTCTCAGGATACATGTGATACAAAAACATTTGAATATCTTGCCTTACGTTTGTCAGGTCTGCGGGAAGCAAACTTCTACCATAAGCCATTTGAAATCACACTCTAAAGTTCACGACGTAGATAGGAAGACTCTAGAATGCCACTGCGGGGCCAAGTTCCGGACTGATATAGGGTACCGTTTACATATGAGAATCCACAGCGGTTTGAGGCCTTTTAAATGTGAGGAGTGCGAGGAGAGTTTCATATCGGCGTCTCGACGCTCCGATCATATGAAGAGACGTCATAAGAGTGTGAAAGATATGGCGCATGGTTGCGAGCAATGCTTGGCTCGGTTCATCAGGCCTTGGGAGCTGAAGAAGCATTACAAGCTGTCGCATTGTTCGATAGTGGATGTGCAGCCAGCGAAGCGGCAGAGGTCGACTATAAAAGAAGAAACCTTCTGTCCGGGCGGTGTTTGCGTGGCTTGCGCAAGTGCAGCGCTGGCCGCGGAAGAGTTCCGTTTATTCGTCCGCAACGCCGCCTCGCTCTGGCGCCGCGCCATCATCAACCTCTCCCAGCTGCCCTACGAGGCTTCCGACAACGCAAAATCAGTTTGCGCGGTCGTTTCCCCCAACATAACTGTCGATACACACAGCGATCTAGACGCCGGCGATGCGACTGAAGTCATCGATAAATTGCAGTCGAAGTTGATTAAGAAGAAAAACGAGAGAAAACCCCGCGTTCTCCGCACCGGGCTGAACGTAACCTGCCCTGACTGTAACAAGCAGTTCGCAGGTCCTCATTTACTGCAAACGCATCTTCAGAACAGCGATAGGAAAGATGCTTGTGGAATTTGCGGCGCCGTCGTTGTTAAAGGTGCTGGGTTGAAATATCACCTCGCAACGGTGCATAGAGAACCCGCGATCCTGTGCAAAGAATGCCCGACCGTTGTGATCACAGAGGCTGAGCTCAAAGCACATGAGAGCTTAGCTCACAAACCTGGGGCACTAAACTGCACCGCTTGCGGTAGAACCTTTACCCGCAAAGGGTCGTACGAAAGCCATATCCAGATGCACGTCGTCTTGACCTGCAGACTCTGCGGTACGCAATTCTCTAACAGAAGCTGCTTCCGCCAACATAGATCCTGTTGCGAACCCAACGCAAAACCTACATCTATCCCCCGCATACGTCGTTCGAACAACCGCGACCCGGGCCAATACGTCTGCGACTACTGTCAAAAGATGTACAGCTCTCGGCCGCAATTGAAGAATCATATCCTCTGGATCCACTTGGATCACAGGCCGCACCAGTGCTCCTTCTGCGGGAAGCGATTCTACACATCAGCGAGGTTGAACGAGCACACCGTTGTCCATACGAGAGTTAGGAACTTTGAGTGTGACCTATGTGACGCGAAGCTAGTATCGAAAAGTGCTGCGATTTACCACAGACGAAGGCATACGGGGGAGAAGCCCTACATTTGTGACGACTGTGGAGCAGCCTTCATCTCCTCGTCGAGGAGGCTAGAACACGCTAAACGGAAACACAATAGAGGGATTCGGTTCAAGTGTACGGAGTGCACCGCTAGCTTCGTAAGGAGACGGGAGCTTGAGAAACACGTGGCGAAACATCATACAGCCACGGGAAAATCTGAGGCATTAGTAAGGCTCTTCAAGCTTGATGTTATTTCTTAG
Protein Sequence: MSRQVDVKALISHIVKGDGLDKCRVCMGDTSQGQVHLTDTVMMDGDKAVTLSELLEVITGVEVELENALPSSLCLTCSVAAFEAAEFKTLVLRAQRQWNSTVNMLNHIPDHKYAPTSHKILAVLSNNYIKICDEGIKPPVEKPRDIPILKRPGKLQECQCPTCGNTFQYAVQLNKHLRDSVDLLRACHICAEVMSRSKLIKHVKEEHNIKTYPCKKCPAILTNAKLLSDHNLKAHAKGSIKCVDCSYTFLTPQAIYAHQHIHTQRCCPNCDRVFRNRPCYSYHIKKCCKLDLKHKSKHVPVTLQNKENKKVTMGKRGSINHKCICDYCNKTYAAKKFLSAHIQIVHLKNTHRPCVYCGKQFAAAHMSTHLKSHKKSSFKCDHCGVELKSKLGFMQHLRLHTGERPYKCSLCGEHFSSSSRMSEHKRNKHFKSQIVLKNVCTICSAKFRLPSKLKMHMDKVHKCNGMEEVCYKCELCREMFDSCQSLMEDGNTPRQLCQQCMSDITAFLPFLRLCKQSAAYWSFLSENLINLSSQKTFNTAFIFVNDKIDKVTNVFEKRDRNKNKLWHVVTKRINQLESARRTLESDDNEPTKPGKFLYTCVECGAKFTRLENINNHLASQNKRFCAHCEQIIELKAFGAHLESHSIPFYTCKMCSVPFECKYQFIKHKSVHQGRIMCGECKITFPSAHHLNIHVNRKHERASCVKCNKKFSNRICFNKHRSKCKSRISEKYICDHCSKEFSEKGHIKLHIYTMHSKVSSHQCELCGRKFNSACHLDEHKETHNVIPDRYVCPFCGGRYSSSGGYRKHLRHKHYRTNPELKMDMICTCDVDDGPALPPGLCGVCAGDAISAAKFRKLTEKSAKCWSEAAQYLSRIDSESNDTKTLLYVHEEHTLIFYEKRAKSAKSAVKALGNYEKAPTFNRKNPISCPFCGKRVISVQNLNQHLQNSSKAVCICGSLMEKSEICEHLREIHQIEVFECSICHEQFQSNEVLKWHSSKSHGSKSFGCEHCGRGYRNERALRAHYYTHTLFDCSACGRTFENSRCYHHHKTTCKTKHNNDFSIFECHDCGQKYDKKGSLRIHVIQKHLNILPYVCQVCGKQTSTISHLKSHSKVHDVDRKTLECHCGAKFRTDIGYRLHMRIHSGLRPFKCEECEESFISASRRSDHMKRRHKSVKDMAHGCEQCLARFIRPWELKKHYKLSHCSIVDVQPAKRQRSTIKEETFCPGGVCVACASAALAAEEFRLFVRNAASLWRRAIINLSQLPYEASDNAKSVCAVVSPNITVDTHSDLDAGDATEVIDKLQSKLIKKKNERKPRVLRTGLNVTCPDCNKQFAGPHLLQTHLQNSDRKDACGICGAVVVKGAGLKYHLATVHREPAILCKECPTVVITEAELKAHESLAHKPGALNCTACGRTFTRKGSYESHIQMHVVLTCRLCGTQFSNRSCFRQHRSCCEPNAKPTSIPRIRRSNNRDPGQYVCDYCQKMYSSRPQLKNHILWIHLDHRPHQCSFCGKRFYTSARLNEHTVVHTRVRNFECDLCDAKLVSKSAAIYHRRRHTGEKPYICDDCGAAFISSSRRLEHAKRKHNRGIRFKCTECTASFVRRRELEKHVAKHHTATGKSEALVRLFKLDVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00700316;
90% Identity: iTF_00698500;
80% Identity: -