Basic Information

Insect: Eupithecia exiguata
Gene Symbol: Hr39
Assembly: GCA_947086465.1
Location: OX352227.1:3082665-3099307[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.13 9.2e+02 -0.8 3.0 118 163 261 306 135 359 0.57

2 3 4.2e-08 0.00031 20.6 0.1 1 21 438 458 438 471 0.91

3 3 1.3e-63 9.6e-60 203.4 0.0 164 408 500 757 473 757 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.13	9.2e+02	-0.8	3.0	118	163	261	306	135	359	0.57
2	3	4.2e-08	0.00031	20.6	0.1	1	21	438	458	438	471	0.91
3	3	1.3e-63	9.6e-60	203.4	0.0	164	408	500	757	473	757	0.84

Sequence Information

Coding Sequence: ATGAACACCGCGATGTCAAGCGACGCTGACGCGGTGAAGGTTGAGGGGGGTCACGTGTCAGTCACCACGATCAGCATGTCCGGCCCGGAAACGAGCAATGGCCAATTCTCGTATAGCTCGAGTGGGGTCCGCATCAGTGTGTCTTCGGTTCCTCACGACGAAGACTCTACTGATGCTGAAATCTCCAAGATTGACTTCTCTCAACATCAGTACGAGGTCAACATGCGAAACAAGAAGGCTCTGTCTTCGAGTGGGCAGTACGAGGCGAACGATCGCGAACGACCCATGTCTTGGGAAGGAGAGCTCTCCGACTCAGAGATGGTTATCGACACCTCTGCCAATAACGACGAAACCTGCAACTCAACCGATCTCCAATCCTCCCGCGATTCCATCGACACGCTCCGTAACGTGGTCATCAAGCAGGAGCCGATGAAGAGCGAAGGCTTCCAGAGTCTCGACGACCAGCGGGTACTAGATCTCAAGTACCCACCGCTGCAGCAGCATCAGAGAAGCCTCAGTATGAATCGGATACCACTGCTAACCGACACCCCCCTATCTCTACCGCGAAGACCGTCTTCTCCCACAAACTCCGCTAAATCCCTGGCGTTATCCGACCAGGGTACGATGCCAATGCCTCAGACAACCATTGGGGAGATACAGAACCTTACAATCAAGAAGGAGATGTTATCAGAGTTGAAATGCGAACCGTCCTTAGGCATGGAGAAGCTTCTAGGCACAGCATTAGGCTCACCACTCACAGGCAGAATGCAGCGCGTCCAATCCAGTGCCAGTACCGATTCCGCCGTACATTCCATGTACACACACAGTGTGTACAGCAGTCCGTCCGCCAGCCCGCGTGCCAATCGCCACTACACGCCGTCTCTTTCTCGCAACAACAGCGACGCATCGCACTCTTCCTGTTACTCCTACAGCTCTGAGTTCTCGCCTACTCATTCCCCGGTTCAGGGTCGTCACCCCCACGTAGTATACAGAGAAGCCACTGCCGCGTTCCCTGCATCACCAGCTCATGATGAAGATGCCGAGACAGACGACAGACTGCATCATCACCAGGGGATCAGTCGACAACAGCTTATCAACAGTCCATGTCCGATATGCGGCGACAAAATCAGTGGTTTCCACTACGGGATCTTCTCCTGCGAATCCTGTAAGGGTTTCTTCAAGCGAACGGTTCAGAATCGGAAGAACTACATGTGTTTACGCGGCAGCAACTGTCCAGTTACTGTTGCTACACGGAAGAAGTGTCCCGCTTGTCGGTTTGACAAGTGTCTGCAGTGTGGCATGAGGTTGGAAGCAATAAGAGAAGACAGAACACGAGGAGGCAGATCAACATACCAATGTTCGTACACACTATCAGGCGCGGCCTCAACCGGATCCCTGCTGTCCGCGCACGTCCCAACCACATTACGGCACGCTTCAAGTCTCAACTGTGTAAACGGTCCTGGTTCATACAACAGCAGAGGGGAATCAAGCAATAGCCGACTAACGCCCGAAATTCCACCGTTATTGCAAGAAATAATGGACGTGGAACACTTATGGCAATACAACGTGTCAGAAGTAAACCGGCTCGGCAAGTCCACCGGTGGGAGTCCCTCGGCCAATCCCTTGCTAGCAGCGAGTGGGATCACGGCACAGAACTCGAGCCCTGACTTCCTAGCGGACTTGTGCGATATAGCTGACCATAGGCTATACAAAATTGTGAAGTGGTGCAAGAGTCTTCCCTTGTTCAAGAACATCTCGATAGATGATCAAATAAACCTACTAATAAACAGCTGGTGCGAGCTCCTCGTGCTGTCGTGCTGCTACCGCGGTGTCAGCACGCCGGGCGAGGTGCGCGTGGGCGGCGGACGCGGCATCACGCTGCAGCATGCGGCCAAGCTAGGCTTGACGCCGTGCATAGAGCGTATGCTGAGTTTCACGGACCACTTGCGGCGGCTAAGAGTGGATAGATACGAGTACGTGGCGTTGAAGGTCATTGTACTTCTGACCTCAGACGCACCAGATCTTCGTGAATCAGAGAAGGTTAGAGCGTCACAAGAGAAAGCGCTGGCCGCATTACAAGCATACATCGCCACGCACTCGCCGCAAACTCCGGCCAAGTTCGGAGAGTTGCTGCTGAGGATTCCTGAACTGCAGCGGACTTGCCAATTCTTCATGCAAGTCGGCAAAGAGATGCTGAATCCAGCAAATAAAAACAAAGATGGCGAAGGACCGAGCTTCAATCTACTCATGGAACTGTTGCGAGGTGACCATTGA
Protein Sequence: MNTAMSSDADAVKVEGGHVSVTTISMSGPETSNGQFSYSSSGVRISVSSVPHDEDSTDAEISKIDFSQHQYEVNMRNKKALSSSGQYEANDRERPMSWEGELSDSEMVIDTSANNDETCNSTDLQSSRDSIDTLRNVVIKQEPMKSEGFQSLDDQRVLDLKYPPLQQHQRSLSMNRIPLLTDTPLSLPRRPSSPTNSAKSLALSDQGTMPMPQTTIGEIQNLTIKKEMLSELKCEPSLGMEKLLGTALGSPLTGRMQRVQSSASTDSAVHSMYTHSVYSSPSASPRANRHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHVVYREATAAFPASPAHDEDAETDDRLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGSNCPVTVATRKKCPACRFDKCLQCGMRLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHVPTTLRHASSLNCVNGPGSYNSRGESSNSRLTPEIPPLLQEIMDVEHLWQYNVSEVNRLGKSTGGSPSANPLLAASGITAQNSSPDFLADLCDIADHRLYKIVKWCKSLPLFKNISIDDQINLLINSWCELLVLSCCYRGVSTPGEVRVGGGRGITLQHAAKLGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPDLRESEKVRASQEKALAALQAYIATHSPQTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKNKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01161468;
90% Identity: iTF_00702959;
80% Identity: iTF_00699324;