Edod007939.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eupithecia dodoneata
Gene Symbol
-
Assembly
GCA_947044255.1
Location
CAMRHC010000039.1:5030135-5036943[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 3.6e-07 2.2e-05 25.0 1.5 1 23 435 457 435 457 0.99
2 8 8.5e-07 5.2e-05 23.8 1.4 1 23 463 485 463 485 0.98
3 8 8.7e-06 0.00053 20.6 0.5 2 23 494 515 494 515 0.98
4 8 9.5e-06 0.00058 20.5 0.6 1 23 521 543 521 543 0.99
5 8 9e-08 5.5e-06 26.9 2.1 1 23 549 571 549 571 0.98
6 8 1.4e-06 8.3e-05 23.1 2.6 1 23 577 599 577 599 0.97
7 8 1.3e-05 0.00079 20.1 6.3 1 23 605 627 605 627 0.97
8 8 0.00013 0.0079 16.9 2.1 1 21 633 653 633 654 0.95

Sequence Information

Coding Sequence
ATGTGTGAATGGCTGTCGTTGGGAGAATGGAGCGACGTGCAACTTTTGTGTGGCGGTCGCTCTTTTAGCGCCCACAGAGCAGTCCTTGCAAGTGTCAGTACTTTCCTAAGGCGTATCCTGCTAACAAGCCCTGATGAAGCAACAACATTCATAGTTCTACCCGACTTTGATTTAGAAGCAATGTCTTCAGTTTTGTATTACATATACAACGGAGAAGTGGTCCTTCAAAAGAACAAGTTGGGTCTGTTTTTGGAGATAATTCATGCAATGCAGATTTATATTGATTCCCAATATTTGTCAAAAATATGTGCTAAAATTCAGGATATAGAAGAGAAATATGTAGAATTAGCAAAATATTGTCAAAGAAAATCCTTGCCTAGTCAGATATTCACTCTCGGATTGAATGTCGATAGTGAGcaaatgtttaatattaaaaaatgtaaagagACACAGAGACCTATTGTGAAATATTCACAGAGCAACATAGATTTGAACGATTACAACGTACGATATCTGAATAAGAGTGAGCTCGACGAGTCTCGTTTAGGCAATCTGAAATCGCCATACGAAGACCGACAAAGGAACACTTTACTACGTGATTTATTTATCGAGACATATCCTCGAAACGGTAATGTTAACGGTCTGACGGAAAGCGTGCTGGCAATATCAAACGAATGCTATCAGTCTCCGGCATCTGAGCTCTTAGAGAATGCAAATAGCAGACATCTCAGCAttggcggcgcgcgcgcaggaCGCCCTAAAACAGCATCTTGTCATTCTTTACATTCGCCGGCCGTCGACAAATTGCAACTGACTTACAACACCAGTTCGGAATGTAGCAAACCAATTGATGCAGCAGATTTTCTAGCTAATCGATACCCAACAGATTTTCAAGACATCTTGCGATTTTACAAATTTAACAAACCTATTTTGGATGTAGACAGACATGTCTTTGACAATGCAGTGCAGACCACATCAGGAACAGATgtcaataaattacttttggaTCCAATTAAGTATCGCCAAAATAcagaaaactttataaaacagAGTAATATACCAGTAGAAAATGAAAGAGAAAACAAAACGGAAACTACGAAATCAAAAGCTCCTTCAAAAGTTATATTCAATCAAGTCTTGGAAAGCCCTTGGCATgacCAAAATATAGAGAATCGAAATGATACGAACAACAATGTCAAGATACCAGCATCTTTAGCAGAAAGAGAGTTGTCTGAAAGGCAATTAGAACAACCCGTGCAAGAGTTTGATAACAGTCCTGCAGTTATTGAAAACAGGGAATGTTTCAAATGCACCAGTTGTGAccagGTATTCACAACCAACGAGTCCCTCACTATCCACATGCGTCGCCACTCCTCCAGCGCGCGTTACTCTTGCGGCGAGTGCGGGAAGACGTTCTCTCAGCTACGGAACTTCAAGTACCACATGTCCATACACAGAGGCACTCGCGAGTTCGCGGCGACTTGCAGTGTCTGCGGGAAGTATTTCAATGATAGGGGATACTTGAGCAGCCATATGAAGATTCATAGAAATCGCAAGGAATATAAATGCTCGCTGTGCCCCAAGTCGTTCAATCAGCGAGTCGCCTACAACATGCATGTGCGGATTCACACAGGAGTAAAACCGCACGTTTGCGAGGAATGTGGCAAGGCGTTCTCCCGCAAGATGCTTCTGAAGCAGCATCAGCGCACGCACTCCGGTGAGCGCCCCTACGCCTGCCCGCACTGCGATAAGTGCTTCGCTGATCGTTCTAACATGACTCTGCATGTTAGATTGCACACTGGCGTAAAACCATTCTCCTGCCCTATGTGCCCAAAGTCGTTCACAAAGAAGCACCATCTGAAATCTCACCTGAACTTCCACACGGGATCCAAGCCTTACTCCTGTCCGCGCTGCCATCTTGCCTTCACACAGTCTTCGAACATGAGGACTCATTACAAGAAGTGTACCGCAGAGCCTAGTACCAGCGAATCTATATCTCAGTAG
Protein Sequence
MCEWLSLGEWSDVQLLCGGRSFSAHRAVLASVSTFLRRILLTSPDEATTFIVLPDFDLEAMSSVLYYIYNGEVVLQKNKLGLFLEIIHAMQIYIDSQYLSKICAKIQDIEEKYVELAKYCQRKSLPSQIFTLGLNVDSEQMFNIKKCKETQRPIVKYSQSNIDLNDYNVRYLNKSELDESRLGNLKSPYEDRQRNTLLRDLFIETYPRNGNVNGLTESVLAISNECYQSPASELLENANSRHLSIGGARAGRPKTASCHSLHSPAVDKLQLTYNTSSECSKPIDAADFLANRYPTDFQDILRFYKFNKPILDVDRHVFDNAVQTTSGTDVNKLLLDPIKYRQNTENFIKQSNIPVENERENKTETTKSKAPSKVIFNQVLESPWHDQNIENRNDTNNNVKIPASLAERELSERQLEQPVQEFDNSPAVIENRECFKCTSCDQVFTTNESLTIHMRRHSSSARYSCGECGKTFSQLRNFKYHMSIHRGTREFAATCSVCGKYFNDRGYLSSHMKIHRNRKEYKCSLCPKSFNQRVAYNMHVRIHTGVKPHVCEECGKAFSRKMLLKQHQRTHSGERPYACPHCDKCFADRSNMTLHVRLHTGVKPFSCPMCPKSFTKKHHLKSHLNFHTGSKPYSCPRCHLAFTQSSNMRTHYKKCTAEPSTSESISQ