Basic Information

Gene Symbol
-
Assembly
GCA_951509635.1
Location
OX608075.1:129323356-129325488[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.62 1.2e+02 4.9 1.0 1 23 190 215 190 215 0.92
2 12 0.00015 0.03 16.3 2.3 1 23 221 243 221 243 0.98
3 12 0.65 1.3e+02 4.9 1.4 3 11 279 287 278 301 0.89
4 12 0.00017 0.034 16.1 6.0 1 23 307 329 307 329 0.98
5 12 7.6e-06 0.0015 20.4 0.3 1 23 335 357 335 357 0.98
6 12 8.9e-05 0.018 17.0 4.3 2 23 363 384 362 384 0.97
7 12 0.008 1.6 10.9 1.0 3 20 393 410 392 414 0.88
8 12 6.6e-05 0.013 17.4 1.0 1 23 439 461 439 461 0.99
9 12 0.00075 0.15 14.1 2.3 1 23 467 490 467 490 0.96
10 12 9.7e-05 0.019 16.9 0.2 1 21 496 516 496 519 0.90
11 12 3.5e-05 0.007 18.3 0.3 1 23 525 547 525 547 0.96
12 12 8.9e-06 0.0018 20.2 2.1 1 23 553 575 553 575 0.98

Sequence Information

Coding Sequence
atgagTGCTGGAGACAAGATTTGCCGAACGTGCGGCAAAGGATCCGATTTAAAAGACGAAACAGTTCTCTTTCCAATCTTTAACTCACCCAATTTTGAGTCGgaactaaaaattatattagaaGAATTTGAAACGTGGAATTTAAATATATCCGAAAACGATGGTCTACCGCAACAAATTTGCTTAACTTGCTTTGATAGTTTTTGTCAAATTCATAATTTCCGTGTTTTGTGCGTGGAAACCCAAATGAATTTTGGAGAAATGTGCACGGGCTTGGACATAATTATTAAAGATAAAATCTCAGACGAAGATTATGATTCTCCGGAGCATTTTAATTTCGAAGAATTAGTGATTGTTCAAGAGCACTATAAATTTCCTGGTGATGAAGAACTCCCAGAACTTCCGAAACCATCACCAACActaacaccaacaccaacactaACAGATCCGATTGACACGATAAAACAAGAACTTCCAGACCCTGTTAAAAAACCAGAACCCAAAAAAATCATAAGGCCAAACTATGATCCAAGAGAAGTAAAAGATATTGTTCCCGAATATCGAGAGCATCAATGTGATTATTGTCTGGACGTTGTTTGTTTCGATAACGAAGAACAGCTGAATGAGCATGTAAATCTAATGCATTCAACAAGCGAGCCCTATACGTGCCCCAAATGTGACAAGCGTTTCGATAAAAAAGCCAAACGAAACAATCATTCTCGAATACACTTTGCGCCAGCTAGTGATTGTCAAACATGCGGCAGAAAAGTGAGAGGAGGCGAGAATATGATGTTGCAGCACATCGAATATTGTCACATTGAAAAGGACCGTGCCTGCCCGACTTGtggaaaagaatttaaaatggtCTCATTAAAAAGATTCAATTACCATCTGACGTGGCATGACGAATCCAAGTTGCACAAATGCAAATTTTGTGACAAAAAGTTCATTCAAACTACCCATTTGGTAGTGCACGAGAGAACTCATACCGGAGAGACTCCATACAAATGCGACAAATGTCAaatggCCTTTAAAAACCCAAATCTTTTAGCCAATCACATTAAAGGCCATGGAGGAAAAGACATCACATGTCCTGAGTGTCCTAAAAggtTTCATCATCGCCATGCTCTGACAATGCATATGACAATTCATGATCCAAGAAGAAAACGGCCTCATTGTGAGATATGCAACATAACTTATCGCACTGCAATAAACTTACGCTTGCACAACTACCAAAAGCACGATGGACCAGCATCAGAGTCAATACTCAACATATTGAGTAAACGACAAATAAAGCACCCGGTTATTAAGCCTTACAAATGCAATCTGTGTCCTGAGGCGTTTGTCCTGCACACACAGTTGGTAAAGCATTTGAAGATGCACACCGAGGATAGGCCGTTCTCGTGCAAACTCTGTATTAAGACTTTCAAAAGAGTGGCGCATTTAAAATTGCACATGGATTCGctgcatttaaacaaaaagccATTTAAGTGTGCTCTATGCGGATGGGCTTTCCCGCAGAGGAATAATTTAAAAGAGCACTTTGCTGCCAAGCATGcgaATACAAGAGACTTCAAATGTGATATTTGTTCAAAGGATTTTGCGACACCGAAGGCTCTTAGAATACATAAAGTATCACATTCTGAGAAGAAGCCATTTGTGTGTACAGTATGTAATAAGAGTTTCAAACAAATGTTTGTTCTGAAAAATCATATGAATCGTCATTTAAGGAAGAACGAAGCCGACATTGAAGGTGGTGATATAACGGATATTGTAGTTCGAGATGAAATTGATGATGAATTGTAA
Protein Sequence
MSAGDKICRTCGKGSDLKDETVLFPIFNSPNFESELKIILEEFETWNLNISENDGLPQQICLTCFDSFCQIHNFRVLCVETQMNFGEMCTGLDIIIKDKISDEDYDSPEHFNFEELVIVQEHYKFPGDEELPELPKPSPTLTPTPTLTDPIDTIKQELPDPVKKPEPKKIIRPNYDPREVKDIVPEYREHQCDYCLDVVCFDNEEQLNEHVNLMHSTSEPYTCPKCDKRFDKKAKRNNHSRIHFAPASDCQTCGRKVRGGENMMLQHIEYCHIEKDRACPTCGKEFKMVSLKRFNYHLTWHDESKLHKCKFCDKKFIQTTHLVVHERTHTGETPYKCDKCQMAFKNPNLLANHIKGHGGKDITCPECPKRFHHRHALTMHMTIHDPRRKRPHCEICNITYRTAINLRLHNYQKHDGPASESILNILSKRQIKHPVIKPYKCNLCPEAFVLHTQLVKHLKMHTEDRPFSCKLCIKTFKRVAHLKLHMDSLHLNKKPFKCALCGWAFPQRNNLKEHFAAKHANTRDFKCDICSKDFATPKALRIHKVSHSEKKPFVCTVCNKSFKQMFVLKNHMNRHLRKNEADIEGGDITDIVVRDEIDDEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00694090;
90% Identity
iTF_00694090;
80% Identity
-