Basic Information

Gene Symbol
-
Assembly
GCA_945859775.1
Location
CAMAOS010000208.1:227736-229886[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 1.5 1.9e+02 3.6 1.0 1 23 196 221 196 221 0.91
2 11 0.00014 0.018 16.3 2.3 1 23 227 249 227 249 0.98
3 11 0.6 78 4.9 2.0 2 11 284 293 284 307 0.88
4 11 0.00016 0.02 16.1 6.0 1 23 313 335 313 335 0.98
5 11 7.2e-06 0.00093 20.3 0.3 1 23 341 363 341 363 0.98
6 11 0.0075 0.98 10.8 1.0 3 20 403 420 402 424 0.88
7 11 6.2e-05 0.008 17.4 1.0 1 23 449 471 449 471 0.99
8 11 0.0007 0.091 14.1 2.3 1 23 477 500 477 500 0.96
9 11 9.1e-05 0.012 16.9 0.2 1 21 506 526 506 529 0.90
10 11 1.5e-05 0.002 19.3 0.3 1 23 535 557 535 557 0.98
11 11 1.9e-05 0.0024 19.0 2.0 1 23 563 585 563 585 0.98

Sequence Information

Coding Sequence
ATGAGTGCTGGAGACAAGATTTGCCGAACATGCGGCAAAGGATCCGATTTGAAAGACGAGACAGTTCTCTTCCCGATCTTTAACCCACCCAATTTTGAGTCGGAACTAAAAATTATATTAGAAGAATTTGAAACTTGGAATTTAAACATAGCCGAAAACGATGGTCTGCCGCAACAAATTTGCTTAACTTGCTTTGATAGTTTTTGTCAAATTCATAATTTCCGTGTTTTGTGTGTGGAAACCCAAATGAATTTCGGAGAAATGTGCACGGGCTTGGACATAATTATTAAAGATCAAATCTCAGACGAAGATAATGACTCTCCGGAGCATTTTAACTTCGAAGAATTAGTGATTGTTCAAGAGCACTATAAATTTCCTGGTGATGAAATTCCAGAACTTCCAGAACTTCCGAAACCAGAGCTTCCAGAACTTCCGAAACCATCACCAACACTAACACCAACAGACCCGGTCGACACGATAAAGCAAGAACCTCCAGAACCGGTTAAAAAACCAGAACCCAAAAAAATCATAAGGCCAAACTATGATCCAAGAGAAGTTAAAGATATTCTTCCCGAATATCGAGAGCATCAATGTGATTATTGTCTGGACGTGGTTTGTTTCGATAACGAAGAACAGTTGAGTGAACATGTAAATCTCATGCATTCAACAAGCGAGCCTTATACGTGCCCCAAATGTGACAAGCGTTTTGATAAAAAAGCCAAGCGAAACAATCATTCTCGAATACACTTTGCGCCAGCTACAAATTGTCAAACATGCGGCAGAAAAGTGAGAGGAGGCGAGAATATGATGTTGCAGCACATTGAATACTGTCACATTGAAAAGGACCGTGTCTGCCCGACTTGTGGAAAAGAATTTAAAATGGTCTCATTAAAAAGATTCAATTACCATCTGACGTGGCATGACGAATCCAGGTTGCACAAATGCAAATTTTGTGACAAAAAGTTCATTCAAACTACCCATTTGGTAGTCCACGAAAGAACTCATACCGGGGAGTCTCCATACAAATGCGACAAATGTCAAATGGCCTTCAAAAATCCAAATCTTTTAGCCAACCACATTAAAGGTCATGGAGGAAAAGACATCACATGTCCTGAGTGTCCTAAAAGTACTTACATTAGGTTTCATCATCGCCATGCTTTGACAATGCATATGACAGTTCATGATCCAAGAAGAAAACGGCCTCATTGTGAGATATGCAACATAACTTATCGCACTGCAATTAACTTACGTCTGCACAACTACCAAAAGCACGACGGGCCAGCATCAGAGTCAATACTCAACATATTGAGTAAACGACAAATAAAGCATCCGGTTATTAAGCCTTACAAATGCAATCTGTGTCCTGAGGCGTTCGTCCTGCACACACAATTGGTAAAGCATTTGAAGATGCACACCGAGGATAGGCCATTCTCGTGCAAACTCTGTATTAAGACTTTCAAAAGAGTGGCGCATTTAAAATTGCACATGGATTCGCTGCATTTAAACAAAAAGCCATTCAAGTGTGCTCTATGCGGATGGGCTTTCCCGCAGAGGAATAATTTAAAAGAGCACTTTGCTGCCAAGCATGCGAATACAAGAGACTTCAAATGTGATATTTGTTCAAAGGATTTTGCGACACCAAAGGCTCTTAGAATACACAAGGTAACACATTCTGAGAAGAAGCCATTTGTGTGTACAGTCTGTAATAGGAGTTTCAAACAAATGTTTGTACTTAAAAATCATATGAATCGCCATTTAAGGAAGAACGAAGCCGACATTGAAGGTGGTGATATAACGGATATTGTAGTTCGAGATGAAATTGATGAGGAATTGTAA
Protein Sequence
MSAGDKICRTCGKGSDLKDETVLFPIFNPPNFESELKIILEEFETWNLNIAENDGLPQQICLTCFDSFCQIHNFRVLCVETQMNFGEMCTGLDIIIKDQISDEDNDSPEHFNFEELVIVQEHYKFPGDEIPELPELPKPELPELPKPSPTLTPTDPVDTIKQEPPEPVKKPEPKKIIRPNYDPREVKDILPEYREHQCDYCLDVVCFDNEEQLSEHVNLMHSTSEPYTCPKCDKRFDKKAKRNNHSRIHFAPATNCQTCGRKVRGGENMMLQHIEYCHIEKDRVCPTCGKEFKMVSLKRFNYHLTWHDESRLHKCKFCDKKFIQTTHLVVHERTHTGESPYKCDKCQMAFKNPNLLANHIKGHGGKDITCPECPKSTYIRFHHRHALTMHMTVHDPRRKRPHCEICNITYRTAINLRLHNYQKHDGPASESILNILSKRQIKHPVIKPYKCNLCPEAFVLHTQLVKHLKMHTEDRPFSCKLCIKTFKRVAHLKLHMDSLHLNKKPFKCALCGWAFPQRNNLKEHFAAKHANTRDFKCDICSKDFATPKALRIHKVTHSEKKPFVCTVCNRSFKQMFVLKNHMNRHLRKNEADIEGGDITDIVVRDEIDEEL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00694890;
90% Identity
iTF_00694890;
80% Identity
-