Basic Information

Insect: Eupeodes corollae
Gene Symbol: topi
Assembly: GCA_945859775.1
Location: CAMAOS010000314.1:756176-766435[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 1 1.3e+02 4.1 1.7 1 23 250 274 250 274 0.92

2 13 0.079 10 7.6 4.0 1 21 280 300 280 303 0.80

3 13 6.5 8.4e+02 1.6 0.5 1 9 308 316 308 318 0.87

4 13 0.68 88 4.7 4.1 1 13 337 349 337 361 0.77

5 13 3.1e-06 0.0004 21.5 3.6 1 23 367 389 367 389 0.98

6 13 0.0032 0.42 12.0 1.2 1 23 395 417 395 417 0.96

7 13 3.1e-05 0.004 18.3 0.9 1 23 423 445 423 445 0.99

8 13 2.4e-05 0.0031 18.7 1.1 1 23 451 474 451 474 0.92

9 13 0.00028 0.036 15.3 2.6 1 23 489 511 489 511 0.98

10 13 6.7e-05 0.0087 17.3 1.8 1 23 516 539 516 539 0.97

11 13 0.00016 0.021 16.1 1.9 1 23 545 567 545 567 0.97

12 13 3.7e-05 0.0048 18.1 2.0 1 23 572 594 572 594 0.99

13 13 3.1e-07 4e-05 24.6 2.4 1 23 600 622 600 622 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	1	1.3e+02	4.1	1.7	1	23	250	274	250	274	0.92
2	13	0.079	10	7.6	4.0	1	21	280	300	280	303	0.80
3	13	6.5	8.4e+02	1.6	0.5	1	9	308	316	308	318	0.87
4	13	0.68	88	4.7	4.1	1	13	337	349	337	361	0.77
5	13	3.1e-06	0.0004	21.5	3.6	1	23	367	389	367	389	0.98
6	13	0.0032	0.42	12.0	1.2	1	23	395	417	395	417	0.96
7	13	3.1e-05	0.004	18.3	0.9	1	23	423	445	423	445	0.99
8	13	2.4e-05	0.0031	18.7	1.1	1	23	451	474	451	474	0.92
9	13	0.00028	0.036	15.3	2.6	1	23	489	511	489	511	0.98
10	13	6.7e-05	0.0087	17.3	1.8	1	23	516	539	516	539	0.97
11	13	0.00016	0.021	16.1	1.9	1	23	545	567	545	567	0.97
12	13	3.7e-05	0.0048	18.1	2.0	1	23	572	594	572	594	0.99
13	13	3.1e-07	4e-05	24.6	2.4	1	23	600	622	600	622	0.98

Sequence Information

Coding Sequence: ATGTGCAGTGTGTTCAAATTAGATTTAAATAAATATAGTATTGAAGATGTGTGCAGAACTTGTGGTAGATGTGACGTTATAACATCTGCAAGTCTAGTGAATATTTTCGCTTCCGACTCTGAAGCTGTTCTAAATATTCTTCGGCAATTCAATTTATGGAAATTAAATATATCTGAAGATGACAGCCTGCCCCAAAAAATGTGTAAACAATGTGTTGGCAAATTCACCCTGGTCGACAATTTTCGCAAGCAATGTGAAAATATTCAAAATGCTTTTAAAATACTCCTATTTGAGCAACGTAGGTTGAAATCAATGAAAAAGGTTGAAAAATTACCCAATGTTCAGCCAAAACTGGAGCAGCAATTCACGGCCGATGAGAGCCAGTCATTTGAGTGTTTTGACGAGATTCCTTTTGAAGATGGAGAGTTTAAGAGTGTTCAGTACTTTGAGCTCGAGCCCCACAAACCTTTAGACTCGAACAGTGAATTTGTTAAAGGGAAGTCCTCGGAAGGAAAACAAAAACCTGAAATGCCAACGGCGGCGCCTATTGATGGTACATCAGATTTGTTTTATGATGATAACAATGACGATGGAGCCATCGAAGACGACGATTGGAATACGGTATCAGAGGACGTGGTTCCAAAACTAGAGCGAAATGATGATGATGAATCAAGCTTAGATTCCGATTTGCTAAGCTCAGATGATGAACGCAAAATTAACCGTAAAAGCAAAGTAAGGCCCAATCAGTTTAAATGTGAATATTGTAAAAACTTCTGCTTGGAAAATCAAGAGGATCTGGATAATCATGTTAAAGAAATCCATTCAACTGAAACCCCATACACATGCTCTCTTTGTACAAAAACCTTTACAAATGCCAAACAACGAAATTGCCATTTTATGGTGAGCCATAAGTGGAAGTCACATGAATGTGATGTATGTCACAAAATGATAAAAGGCGGCAAGCCAGGTCTGAAAAATCACAAAGATAATGTTCACAATAAATCCGACCATGAGTGTACTATTTGCCATAAAAAGTTCGAAAATATCTCCTTGAGTCGGTTTAGGTATCATTTAAGGTGGCATGATAGCTCCAAGTTGTTTTCGTGCAAATCCTGCGATAAAAGTTTTGTCACTCGATATCACCTCGAAGAACATGAACGTACACACACGGATGAAAAGTCCTTCCTGTGCAATATATGCGGTCTAGGACTGCGGTGCAAGCAAAATTTAATTTGGCACATGAAGACACATACGGGAGAAAGGACGTATCAGTGCAATCAATGCAATAAAGCTTTTCCAACACCAACTGCGCTAGCGTGTCATATAAAAACTCACAGTAACGAAAAAAAACACGAATGTGAAATTTGCAATAAACTCTTTAAAACAAAAGGAAGCCTCAAAACGCACATTGGTAATGTACACAAAGTCGATTTTAATGATGGAACTCCAAACTCTTCGCCACGCTATTGTTGTCAATTGTGTCCGAGAAATTTCATCTTCGAACGCGATCTCATTAAGCATTTAAAAACGCACGAACATAGGCGCCATGTTTGTGAGGTATGCGGATTGTCCTACCTACAATCTTCCCACCTTAAAAAACATATGGATACTGTGCATCTGAATATTAAACCTCATGTATGTTCTATTTGTGGTCATGCGTTTCCATTTGAATTTAATCTTAAACAACACGAGCTTACACATAAGGAAAAGGGGTTTAAGTGTATGATGTGCGATAAGGCCTTTACGTTGCATCCATCATTGGTTTCCCATCAGAGAACTCACACCGGCGAAAAACCATACCAATGCCATATATGTCAAAAGGCATTCACAAATAGAGGAAATCTTAAAAGTCATGTGGAGAAACATTTAATAGAGCAGAAACAAAATCAGACTTTTACACAAATTGTCTTACCAGTTATCCCTGCTTCAGCAGAAATTCCGCAACCGTCAGAGCTGAATATATTTGATATAAACAGTTCGTGTGATCAAACAGAACAGGAAGATTTTAGCAATCAGCTTATCAATCAATGTGAACTGGAATCATTAAAATAA
Protein Sequence: MCSVFKLDLNKYSIEDVCRTCGRCDVITSASLVNIFASDSEAVLNILRQFNLWKLNISEDDSLPQKMCKQCVGKFTLVDNFRKQCENIQNAFKILLFEQRRLKSMKKVEKLPNVQPKLEQQFTADESQSFECFDEIPFEDGEFKSVQYFELEPHKPLDSNSEFVKGKSSEGKQKPEMPTAAPIDGTSDLFYDDNNDDGAIEDDDWNTVSEDVVPKLERNDDDESSLDSDLLSSDDERKINRKSKVRPNQFKCEYCKNFCLENQEDLDNHVKEIHSTETPYTCSLCTKTFTNAKQRNCHFMVSHKWKSHECDVCHKMIKGGKPGLKNHKDNVHNKSDHECTICHKKFENISLSRFRYHLRWHDSSKLFSCKSCDKSFVTRYHLEEHERTHTDEKSFLCNICGLGLRCKQNLIWHMKTHTGERTYQCNQCNKAFPTPTALACHIKTHSNEKKHECEICNKLFKTKGSLKTHIGNVHKVDFNDGTPNSSPRYCCQLCPRNFIFERDLIKHLKTHEHRRHVCEVCGLSYLQSSHLKKHMDTVHLNIKPHVCSICGHAFPFEFNLKQHELTHKEKGFKCMMCDKAFTLHPSLVSHQRTHTGEKPYQCHICQKAFTNRGNLKSHVEKHLIEQKQNQTFTQIVLPVIPASAEIPQPSELNIFDINSSCDQTEQEDFSNQLINQCELESLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00894292;
90% Identity: iTF_01318490;
80% Identity: -