Basic Information

Gene Symbol
-
Assembly
GCA_030522745.1
Location
JAPYZB010005270.1:5208-8096[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.45 1.1e+02 5.5 0.0 3 20 121 137 120 139 0.93
2 14 0.0013 0.33 13.5 2.3 1 20 146 165 146 168 0.94
3 14 0.0014 0.36 13.4 0.7 1 23 174 197 174 197 0.90
4 14 8.2e-06 0.0021 20.5 0.9 1 23 203 225 203 225 0.98
5 14 2.4e-05 0.0059 19.0 0.6 1 23 372 394 372 394 0.98
6 14 0.0068 1.7 11.3 0.1 2 20 403 421 402 423 0.93
7 14 0.00043 0.11 15.1 2.6 1 20 445 464 445 467 0.92
8 14 0.024 5.9 9.6 0.4 1 23 472 495 472 495 0.95
9 14 8.8e-06 0.0022 20.4 0.4 1 23 501 523 501 523 0.98
10 14 0.0029 0.74 12.4 6.3 1 23 530 552 530 552 0.98
11 14 0.0005 0.13 14.8 0.4 3 23 560 580 558 580 0.97
12 14 0.0025 0.63 12.6 0.1 1 23 586 609 586 609 0.96
13 14 0.0057 1.4 11.5 0.2 1 23 623 645 623 645 0.97
14 14 0.02 4.9 9.8 0.0 2 23 898 919 897 919 0.96

Sequence Information

Coding Sequence
atggaGACAAACGACAGCGAGTATGTTACGTTTCCACTTGATGGTGTGCACGAAGggaTTCAAGATAATATATCACACGAAGAAATTTGTGAACCTGTTGATGACGACTGTGTGCTACAAGAAGATTTAACCGAAGTTACAGTTGGCGATGTAAGTCAAGATATGACAGAAACTCAAGTTGTGgaaattttaactgaaaattcTGAAGATGAAGGAGAACAGAATGCAGTTGTGTAtcctatttatataaaaagtaaaaagtcttCTCAGCAATTCACAAGTGGTGATGAATCAATGGCTGTTGAAGCTTTACGTCAATTGGGTGGAATGTATCcttgttttgaagataaaaaagttGCTTGTCCTAATTGCGCCAATATGTTTACTCAGGCAGAATTGACTAAACATCAAGCTTTGTGTGCCTCCAGCAACAAACATGCTTGTAGTACATGTggtgaaaaatttgaaagaaaaatagatttaaataatcaCATGGTTTGTCATCAGGTGGATCGGCCTCATGCTTGCAGAACTTGTGGAAATTTATTCCGTTCCAAAGCCAATTTACAAACACACATGGTAGAAGTTCATCAAGTTGAAAGACCACATAAATGTACAGTGTGTGGAGCAGATTTCCAAAGGCCATCAAGTTTGTCAAATCACATGAAAATCCACAGTTATGTTGCAGGAAGAGCTTTAATGCAAAATCAAGGAAATAATGCATCTACAAATgctgaaacaataaaaactgattCTGAGGTGCAAGAAGTTTTGACAGGTACTGTacaaacaatacaaaattttgaaatacctCAGGTACAGTGGGCTGTACAGACATATAATTTTACTACTGACCAAAGCACTGTTGATGGTCTTGTGACACAGACTGATAAAATGGATACATTACAAGAATTTACTGTGTTACCTAATGGAGAAGTAGCACAGTTTGAATATACTCCACAGAACTCAGGGACTAATCAAATTGGTCAACAGTATAGtttaactttaaattctttcaataacTCTGAAACTTTAGTGAAAGTAGAAgcttctaatattaataatgataataaaagagCATACATTGAAATAGATTTACAAGATAATAAAGTACATACATGTAGTCAATGTGGTGTCAGTTTTGCACGTGCAGCCTCTTTAACTTTACATGAAAAGACACATTCAAAGGAATGGGCTTCTCCAGTAGAATGTGAATATTGTGATAAACAGTTTCAAGATGCTAACTTTTTAGCTACTCATCAAGCATCATGTACCAAAAAATTGATGCAAAATAGTACAGAACCAAATACTTCTAATGCAAAATGGGGAAAACATGCTTGTTCTGAATGTGGTAAAAAATTTACcaccaaacaaaaaatgttCAGACATCAATGGattcatagaaaaaaaacacattctTGTGAGGTTTGTGGTTCACAGTATGAGAAACAGTCTGAACTTGATGAGCATAGATTATCAGCCCATCCAGGAGATTCACCATTTACCTGTTTTGTATGTGGAAAAAGTTTTGTGTCTCGACAAGGACTTTGGGAACATGGTAGAACACATGCAGGAAGTCCAGCCTATTTTCATTGTGATACGtgttcaaaaactttttcatctAGGCAAGGGTATTTAATACATCACCGCACACATACAGGGGAACGTCCATATGGTTGTAAGTTTTGTTGGAAAGCTTTTCGGGATGGTGGTACTTTGAGGAAACATGAAAGAATACATACCGGTGAAAGACCTCATGTTTGTCCTTTGTGTGCAAGAGCATTTAATCAAAAAGTAGTTTTACGTGAACATGTCAGATGGGTTCATGCTGCAGGAAAAAATGAAACTGAAGCTGTTGATCCACCATTTCCATGTCCTTTATGTGGAACTTTGACTCAAGACAGAGATGAATTGTGTGCTCATATTGTTAAACATTCTGACCAGATGATAGCTGAAGCTAAAACTAAAAGTAATAATGTGGTTGCAAAGCCTAAACcacaaaaaaagaaaggaaaagctTCAGAAGGGAAGACAAAAGCAGCACAAGCAAAAGTACCAGGAGGAAGAGTAATTACTGCTTCAGAACAAAATGAAGCTTTACTTTCTATTACAGAACATGTGGAGCAGGTAGAGGAAATAGATACCTCAGAACCAACAGAAACACAAGATACTTATTTAGTtgtaaaaaatgagtttaatgATACAGTATGCATAAAAGCTTATACATCTGATGATATTTGTCAAACAGATCAAAATGAGTCCATTAATTTAATAGCAATTGCTAAATCTGAAATTAAAGAGCAAGAAGGAACAGTCAATGTTATAAATAGGCAAGGTAATATTAATACTATGCATTTGATACCTTTTACTACAGCTGGAGAAACAATTCATCTTATTTCTAATAAGCAAAATAATACTTTACATTTAATatcaaaacaaaatgaaaatttgccAGTTTTGACAATTCCTAATCCTCAAACAAATGAAGGCTTTTCAGATGATATGTCACAAATCGATAATTCTGAGGCAACAATTGAAGTGCATACTAGTGATTCTCCAATAAATGCCGAAGAATGTGAAGAAATTCACACAGAAACTATGATAATTGAAAGTGTTGATCTAAAGTCTGAATTTATTAAACATGAGCAAACTATGAACGAAGAAGAAAGTGATGATGAAAGTGAGGAATTAGTGTGTGGCATTTGTGGAAATGATTTTGATGACAAGAATGTGCTGATGGAGCATGTGAAGAttcacatataa
Protein Sequence
METNDSEYVTFPLDGVHEGIQDNISHEEICEPVDDDCVLQEDLTEVTVGDVSQDMTETQVVEILTENSEDEGEQNAVVYPIYIKSKKSSQQFTSGDESMAVEALRQLGGMYPCFEDKKVACPNCANMFTQAELTKHQALCASSNKHACSTCGEKFERKIDLNNHMVCHQVDRPHACRTCGNLFRSKANLQTHMVEVHQVERPHKCTVCGADFQRPSSLSNHMKIHSYVAGRALMQNQGNNASTNAETIKTDSEVQEVLTGTVQTIQNFEIPQVQWAVQTYNFTTDQSTVDGLVTQTDKMDTLQEFTVLPNGEVAQFEYTPQNSGTNQIGQQYSLTLNSFNNSETLVKVEASNINNDNKRAYIEIDLQDNKVHTCSQCGVSFARAASLTLHEKTHSKEWASPVECEYCDKQFQDANFLATHQASCTKKLMQNSTEPNTSNAKWGKHACSECGKKFTTKQKMFRHQWIHRKKTHSCEVCGSQYEKQSELDEHRLSAHPGDSPFTCFVCGKSFVSRQGLWEHGRTHAGSPAYFHCDTCSKTFSSRQGYLIHHRTHTGERPYGCKFCWKAFRDGGTLRKHERIHTGERPHVCPLCARAFNQKVVLREHVRWVHAAGKNETEAVDPPFPCPLCGTLTQDRDELCAHIVKHSDQMIAEAKTKSNNVVAKPKPQKKKGKASEGKTKAAQAKVPGGRVITASEQNEALLSITEHVEQVEEIDTSEPTETQDTYLVVKNEFNDTVCIKAYTSDDICQTDQNESINLIAIAKSEIKEQEGTVNVINRQGNINTMHLIPFTTAGETIHLISNKQNNTLHLISKQNENLPVLTIPNPQTNEGFSDDMSQIDNSEATIEVHTSDSPINAEECEEIHTETMIIESVDLKSEFIKHEQTMNEEESDDESEELVCGICGNDFDDKNVLMEHVKIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00309683;
90% Identity
iTF_00693230;
80% Identity
-