Ejap042023.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eumeta japonica
Gene Symbol
L
Assembly
GCA_005406025.1
Location
BGZK01001257.1:108826-118316[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.47 1.1e+02 5.3 5.8 1 23 3 25 3 25 0.97
2 16 7.7e-07 0.00017 23.5 4.3 1 23 31 53 31 53 0.99
3 16 2e-05 0.0044 19.1 0.1 1 23 59 81 59 81 0.98
4 16 0.00023 0.051 15.8 0.1 2 23 94 116 93 116 0.96
5 16 2.1 4.7e+02 3.3 0.2 3 23 140 162 138 162 0.79
6 16 0.22 50 6.4 0.0 3 23 228 248 227 248 0.97
7 16 0.012 2.6 10.4 0.0 2 23 263 284 262 284 0.91
8 16 0.00017 0.038 16.2 0.6 1 23 292 315 292 315 0.95
9 16 0.073 16 7.9 0.0 1 23 320 343 320 343 0.92
10 16 0.012 2.7 10.4 0.2 1 23 403 427 403 428 0.93
11 16 0.00052 0.12 14.6 0.0 2 23 483 504 482 504 0.96
12 16 0.043 9.7 8.6 0.0 1 23 512 534 512 534 0.98
13 16 4.5 1e+03 2.3 1.0 2 23 542 563 541 564 0.91
14 16 0.65 1.5e+02 4.9 0.3 1 23 639 661 639 661 0.94
15 16 0.0025 0.55 12.5 0.1 1 20 669 688 669 691 0.95
16 16 0.039 8.7 8.8 0.6 1 23 698 720 698 720 0.94

Sequence Information

Coding Sequence
ATGCCCTTCCGGTGCGAGTTCTGCTCGCGGCTGTTCAAGCACAAGCGGTCGCGCGACCGCCACGTCAAGTTGCACACGGGCGACCGCAAGTACCGCTGCACGCACTGCGAGGCGGCGTTCTCGCGCAGTGACCATCTAAAGATTCACATGAAGACGCACGACAACCAAAAGCCGTTCCAATGCACAGTATGCAACCGCGGATACAACACGGCTGCCGCGCTCACCTCGCACATGCAGGGGCACAAGCGCGAGCGGGAGCCCGAGCGCCGGCGCGCGTTGCGCTGCCTACGCTGCGGTGACGCCTTCCGACGCCTCGACTTGCTGCAGGCGCATATGAATACGGCGCACGGTCTCGAAGCGGCGATGCTGACGCCACCCCGACGGGTCGCCTCACATCCCGCTCCGACTCTGCTTGCTTGCATGTATTGTACACGAGATACTTTTACGAGTATGGAGCAGCTGCAGTTGCACGTGCGCGCCGCGCATTCCGCGCTGCTCAACGGCGAGACAACAGACTCTGCGTCCCCCGCGGCGCCGGTCTCTCTGCCGGACCAGCCTTTGCCGACGGACTTGAGCCGGCGGGCTGCGGCCCCTACCGACGACACGCCTCCGGCGAAACGGCCACGTTCCGGCTCCGGCTCCGGTACCCCGCAGACGGCGCTCTCTCCCAGCACTTTGCTATGCAATCAATGCGATGCCGCTCTACCCGATTTCGAAGCTTTTCGAGCACATCTAAAGGCCCACCTCGAGGAAGCCGGTTCGGAAGTAGGTAACGAGAGTCCGACGCCGTGTCCACACTGTGGCGCCACGTTCGCAGACGCGGCAGCGAGCGAGCGACATCTGGCGGCGCACTACTTGGCAGCTTCGTGCGAGTACACATGCCATAGCTGTGCGCGTAGCTTCTCCGCTCCGGACGACCTACAAAAGCATCTGCTGGAACTGCACGCGCATCATCTCTACCGTTGCGCACTTTGCAAGGAGATCTTCGACTCCAAAGTAGCGATACAAGTACATTTTGCGGTGGCACATAGCGGCGAGAGCAAAGTGTGGGTGTGCCGAGCGTGCGGCGCGGCCGGTGGCGCGCTGCGCTCCGAAGCGGAAGGCGCGGCGCACGTGCGCGCGCGCCACGCCGCCCGGCGGTGCACGTGCGGAGCTGTACTGGCGGGCGAGCGCGCACTGCGAGCGCATGCTGCTGCGCACGCTCACTACCGCTGTCCCGTGCCGGCCTGCACCGACACCTTCGCGGTCCAATATTTGCTCGAGCGGCATATGCAGGCACACCACGCAGGGCCGCCGCATCAGGGCATGAACGGCGAGGCGAGCAGAACAAAAAGGCCAGATAACAATAACATCCCCGAGCTGGGTGACAGGACTTGCTCACCGTGCTCGGGCGGCCCCGCAGGCGTCGGCGAAGAGCGCAGACGCAAAAACGGCGCAGTAGCTCTACAATGTGCTTACTGCGGGGAGCGTGCGCGCACCCGCGCCGAGCTGGAGGCGCACACGCGTGCCCAttccggcgcggcggcggcccgACACAAGTGTCTCATCTGTGATGAAGTGTTGCCCTCGGCTGCTGTACTCGCTGAACATAAACTTACACACTGCAAGGTGGTGGCTGGTGATACTTGTGCTCGGTGCCGCTCTCGTCTGCCCTCTGAAGAATCATTTTTATCGCACATGGCGCGGCATCATCCCACGTTGCCTGCGCCCTGTGTGGTCTGCAGACAGACTCTCGCTTCGGAAGCGGAAGCGCGCTTGCACGCGCGATTTCATCTCCGCCCGTCCGGGGACGAGCAACGCTGCGCCATATGCTTGCGGCCTCTCGGCGAGGGCGAAGGCGGCGAGGGGGCGCGCGCGTGTGCTTCGTGTTACCGGCGACACGCCGCCCCCGCAcacccgccgccgcccgccgagCACGACTGCAGGCTGTGCCGTCGAGCTCTCGGTTCTCCCACGCGCCTCCAGGCCCACTTAATAGAGCACACTTTCGCGGGTATCGGTGCGTTCACGTGCTATCTATGTTCGGCGGTGTTCACAAGCGCGGGCGGCCTGCAGCGCCACCTCCCTGAACATTCCACCGCGGCGCGACCTTACGATTGCACTCGATGTGGACTTAAGTTTTTCTTTCGCGCCGAACTGGATAATCATGCGTTCGTTCATCTCGAGGAGGCGGAGATCGCTCAGCGTGCTTTCTATGAGGCGTACGCGCGCGGTGCGGCCTGGGCCGCTCTCGCTCCACCCGAAGCACAGCCGCCCGAGATACCCGCGCCGTCTGTACCTTCTATTGCCGACCCGTCTGTCAAGCGTGAACCCGAAGTTAAAGAGGAAAAAGTCAGCGAAGAGTACATCGAAGTggcgtcgccgccgccgccgccgccgccgcccgcgtcGCCGCCGACCGCAGCGCCGCCGGTCGTCAAACAAGAAAAACCAGACGAAGACTGA
Protein Sequence
MPFRCEFCSRLFKHKRSRDRHVKLHTGDRKYRCTHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQGHKREREPERRRALRCLRCGDAFRRLDLLQAHMNTAHGLEAAMLTPPRRVASHPAPTLLACMYCTRDTFTSMEQLQLHVRAAHSALLNGETTDSASPAAPVSLPDQPLPTDLSRRAAAPTDDTPPAKRPRSGSGSGTPQTALSPSTLLCNQCDAALPDFEAFRAHLKAHLEEAGSEVGNESPTPCPHCGATFADAAASERHLAAHYLAASCEYTCHSCARSFSAPDDLQKHLLELHAHHLYRCALCKEIFDSKVAIQVHFAVAHSGESKVWVCRACGAAGGALRSEAEGAAHVRARHAARRCTCGAVLAGERALRAHAAAHAHYRCPVPACTDTFAVQYLLERHMQAHHAGPPHQGMNGEASRTKRPDNNNIPELGDRTCSPCSGGPAGVGEERRRKNGAVALQCAYCGERARTRAELEAHTRAHSGAAAARHKCLICDEVLPSAAVLAEHKLTHCKVVAGDTCARCRSRLPSEESFLSHMARHHPTLPAPCVVCRQTLASEAEARLHARFHLRPSGDEQRCAICLRPLGEGEGGEGARACASCYRRHAAPAHPPPPAEHDCRLCRRALGSPTRLQAHLIEHTFAGIGAFTCYLCSAVFTSAGGLQRHLPEHSTAARPYDCTRCGLKFFFRAELDNHAFVHLEEAEIAQRAFYEAYARGAAWAALAPPEAQPPEIPAPSVPSIADPSVKREPEVKEEKVSEEYIEVASPPPPPPPPASPPTAAPPVVKQEKPDED*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01545077;
90% Identity
-
80% Identity
-